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The map label for this gene is mauR [H]

Identifier: 120611274

GI number: 120611274

Start: 2853934

End: 2854821

Strand: Direct

Name: mauR [H]

Synonym: Aave_2606

Alternate gene names: 120611274

Gene position: 2853934-2854821 (Clockwise)

Preceding gene: 120611273

Following gene: 120611275

Centisome position: 53.32

GC content: 69.48

Gene sequence:

>888_bases
ATGGATTGGGAGAACCTTCGCTATTTCCTGGAACTGGCCCGGACCGGCACGCTGGCCGCCGCGGCACGCCGCACCGGCGT
GGAACACACCACCGTCGCGCGCCGCATCCAGGCCCTGGAGAAACAGATGGGTGAATCCCTGTTCGCCCGCGAAGCCGGCG
GGCACCGGCTCACCGAAGCGGGCCGGCACCTGCTTCCGGCCGTCGAGGCGATGGAGACGGCCGTGCTCGGCGTCGAGCGG
GTGCGGCCCGCCGGCATCGGTCCGGCAGGCCTCGTGCGCGTGGGCGCCACGGAGGGCTTCGGCACGCAGGTGCTCGCTCC
GCACCTCGCGCGCCTGACGCTGCAGTATCCGCACCTCAGCGTGGACCTGCTGGCCTTGCCCCGCATGCTGCATCTGTCCC
GGCGCGAGGCGGACATCGTCATTTCGCTCGAGCGTCCAACCCGGGGCGCCGTGATCGTCTCCAAACTGGCGGACTACACG
CTGCGCCTGTATGGCCAGCGGGACTACCTGGCCCGGCGCCCGGCCATCGCCCGCCGCGAGGACCTGCGCCACCACGCGTT
CGTCAGCTATGTGGACGACCTGCTGTTCACCAAGGAACTGCAGTTCCTCGACCAGCTTGTGCCGCCGGAGCGTTTCGCGT
TTCGCAGCACCAGCGTCGCGGCGCAATACGAGGCGGTACGCGCCGGTGCAGGGCTGGGGGTGCTGCCGGCTTTCCTGGCC
GACAGCGACCCGTTGCTGGAGCGCGTGCTGCCCGATGAGGCACGTTTCACCCGCACGTTCTGGATGAGCATGCCGGCCGA
AGCGAAGTACCAGGCCCGCACCCAGGCCGTGTGGGATTTCCTGAAGGATGTCGGGCTGCAGGAGGCTTCCAGGCTCATGC
CCTCCTGA

Upstream 100 bases:

>100_bases
CTATCCGTGCGAAATTGCAAGATCAATAGAGAAAAATCGCACGGGTGCTTTGCGAAATTGCACAACACAATCCCTGCATC
GAACACGACACCGCCGCCTT

Downstream 100 bases:

>100_bases
TACGCGGTGTTTCAATTCAAAGAAACATTAATGGCGTGCATGACCTGTCAGGTCAAGGTCTTTTCATTCCGGCGTGCAAT
CATGCAGCCATTGCATTCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDWENLRYFLELARTGTLAAAARRTGVEHTTVARRIQALEKQMGESLFAREAGGHRLTEAGRHLLPAVEAMETAVLGVER
VRPAGIGPAGLVRVGATEGFGTQVLAPHLARLTLQYPHLSVDLLALPRMLHLSRREADIVISLERPTRGAVIVSKLADYT
LRLYGQRDYLARRPAIARREDLRHHAFVSYVDDLLFTKELQFLDQLVPPERFAFRSTSVAAQYEAVRAGAGLGVLPAFLA
DSDPLLERVLPDEARFTRTFWMSMPAEAKYQARTQAVWDFLKDVGLQEASRLMPS

Sequences:

>Translated_295_residues
MDWENLRYFLELARTGTLAAAARRTGVEHTTVARRIQALEKQMGESLFAREAGGHRLTEAGRHLLPAVEAMETAVLGVER
VRPAGIGPAGLVRVGATEGFGTQVLAPHLARLTLQYPHLSVDLLALPRMLHLSRREADIVISLERPTRGAVIVSKLADYT
LRLYGQRDYLARRPAIARREDLRHHAFVSYVDDLLFTKELQFLDQLVPPERFAFRSTSVAAQYEAVRAGAGLGVLPAFLA
DSDPLLERVLPDEARFTRTFWMSMPAEAKYQARTQAVWDFLKDVGLQEASRLMPS
>Mature_295_residues
MDWENLRYFLELARTGTLAAAARRTGVEHTTVARRIQALEKQMGESLFAREAGGHRLTEAGRHLLPAVEAMETAVLGVER
VRPAGIGPAGLVRVGATEGFGTQVLAPHLARLTLQYPHLSVDLLALPRMLHLSRREADIVISLERPTRGAVIVSKLADYT
LRLYGQRDYLARRPAIARREDLRHHAFVSYVDDLLFTKELQFLDQLVPPERFAFRSTSVAAQYEAVRAGAGLGVLPAFLA
DSDPLLERVLPDEARFTRTFWMSMPAEAKYQARTQAVWDFLKDVGLQEASRLMPS

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=197, Percent_Identity=28.4263959390863, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=21.3793103448276, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994962, Length=172, Percent_Identity=30.8139534883721, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32952; Mature: 32952

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWENLRYFLELARTGTLAAAARRTGVEHTTVARRIQALEKQMGESLFAREAGGHRLTEA
CCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GRHLLPAVEAMETAVLGVERVRPAGIGPAGLVRVGATEGFGTQVLAPHLARLTLQYPHLS
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHEEECCCCC
VDLLALPRMLHLSRREADIVISLERPTRGAVIVSKLADYTLRLYGQRDYLARRPAIARRE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHH
DLRHHAFVSYVDDLLFTKELQFLDQLVPPERFAFRSTSVAAQYEAVRAGAGLGVLPAFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHC
DSDPLLERVLPDEARFTRTFWMSMPAEAKYQARTQAVWDFLKDVGLQEASRLMPS
CCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure
MDWENLRYFLELARTGTLAAAARRTGVEHTTVARRIQALEKQMGESLFAREAGGHRLTEA
CCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GRHLLPAVEAMETAVLGVERVRPAGIGPAGLVRVGATEGFGTQVLAPHLARLTLQYPHLS
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHEEECCCCC
VDLLALPRMLHLSRREADIVISLERPTRGAVIVSKLADYTLRLYGQRDYLARRPAIARRE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHH
DLRHHAFVSYVDDLLFTKELQFLDQLVPPERFAFRSTSVAAQYEAVRAGAGLGVLPAFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHC
DSDPLLERVLPDEARFTRTFWMSMPAEAKYQARTQAVWDFLKDVGLQEASRLMPS
CCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]