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The map label for this gene is yafC [H]

Identifier: 120611241

GI number: 120611241

Start: 2823031

End: 2823942

Strand: Reverse

Name: yafC [H]

Synonym: Aave_2573

Alternate gene names: 120611241

Gene position: 2823942-2823031 (Counterclockwise)

Preceding gene: 120611246

Following gene: 120611239

Centisome position: 52.76

GC content: 66.34

Gene sequence:

>912_bases
ATGCAGCGACACTTTGAAGACCTGAAGCTGGGCGGCATCGAACTGTTCTGCACGACGGCGGAGCAGCAGAGCTTCACGGC
AGCGGCGAGGGCCATGGGATTGACGCCTGCCGCCGTCAGCCGCTCCATCAGCCGCCTCGAGGCGAGACTGGGCGTCCAGT
TGCTCGTGCGCACGACCAGGCAGGTGCGCCTGACCGAAGCCGGGCAGGCGTATTTCGAGCGTTGCCGCCAGGCCATCACG
CAATTGATCGATGCGGAAAGGGAGGTCACGGGCCAACAGCAGGCACCGACAGGCCTGGTGCGCATCAGCTTGCCTACCCC
CTATGGACACTATCGCGTGCTGCCCCTGCTACCGGCCTTCCGGACCAGGTATCCGGGCATCACGCTGGATGTCCAGCTCA
CCAATCGCAACATCGACTTCGCAGCGGAGGGGTTCGACCTCGCCGTGCGTGGCCGCACCCTGCCGGACTCGGGGCTGGTC
GCCCGCAAGCTGGAGGACGCCGAGCTGGTCGTCGTGGCTACGCCGGCGTACCTGAGCCGGCACGGGCGCCCCACGACGCT
GGAATCGCTGCAGGAGCACGATTGCATCCAGTTCCTGCTGCCCAGTACCGGCCAGCCCACGCCGTGGCTGTTTCGGCAGA
AAGGCGTGGATGTCGAACACCTGACCAGGGGCGGCATCTGCTGCGCGGAGGACATCCTCGGAACCGTGACCCTGGCCCGG
AACGGCGCGGGCCTGTTGCAGACCTACCGGTTCATCGTCGAGGAGGACCTGGCTCGGCGCACACTGGTGCCTGTGCTGTC
CGAGTGGGACGGAGCTTCGCGGCCGTTCTCGCTGCTGTATCCGGCGCAACGGCACATGCCGTTGCGGGTACGGGTGACGA
TCGAATTCTTGCTGGCCAGTCTGGCAGCATGA

Upstream 100 bases:

>100_bases
GATGAGAAGGCGTTTTCATCGTATTGATGACGCCAACGTCCAGAAAGGTGGGATCATTCAATTCACTATTGACACGGAAT
GCCGCAGTGCGGGGGACCTC

Downstream 100 bases:

>100_bases
CTCCCGGGGGCTCTCCCCGGCCTTTCTTCCGCCCGCCGGATCGCCATCGCTGCCGCAGTCAAGCCTGCGAACCTTGCCAG
TTCCCCCGGAGTTCCGCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MQRHFEDLKLGGIELFCTTAEQQSFTAAARAMGLTPAAVSRSISRLEARLGVQLLVRTTRQVRLTEAGQAYFERCRQAIT
QLIDAEREVTGQQQAPTGLVRISLPTPYGHYRVLPLLPAFRTRYPGITLDVQLTNRNIDFAAEGFDLAVRGRTLPDSGLV
ARKLEDAELVVVATPAYLSRHGRPTTLESLQEHDCIQFLLPSTGQPTPWLFRQKGVDVEHLTRGGICCAEDILGTVTLAR
NGAGLLQTYRFIVEEDLARRTLVPVLSEWDGASRPFSLLYPAQRHMPLRVRVTIEFLLASLAA

Sequences:

>Translated_303_residues
MQRHFEDLKLGGIELFCTTAEQQSFTAAARAMGLTPAAVSRSISRLEARLGVQLLVRTTRQVRLTEAGQAYFERCRQAIT
QLIDAEREVTGQQQAPTGLVRISLPTPYGHYRVLPLLPAFRTRYPGITLDVQLTNRNIDFAAEGFDLAVRGRTLPDSGLV
ARKLEDAELVVVATPAYLSRHGRPTTLESLQEHDCIQFLLPSTGQPTPWLFRQKGVDVEHLTRGGICCAEDILGTVTLAR
NGAGLLQTYRFIVEEDLARRTLVPVLSEWDGASRPFSLLYPAQRHMPLRVRVTIEFLLASLAA
>Mature_303_residues
MQRHFEDLKLGGIELFCTTAEQQSFTAAARAMGLTPAAVSRSISRLEARLGVQLLVRTTRQVRLTEAGQAYFERCRQAIT
QLIDAEREVTGQQQAPTGLVRISLPTPYGHYRVLPLLPAFRTRYPGITLDVQLTNRNIDFAAEGFDLAVRGRTLPDSGLV
ARKLEDAELVVVATPAYLSRHGRPTTLESLQEHDCIQFLLPSTGQPTPWLFRQKGVDVEHLTRGGICCAEDILGTVTLAR
NGAGLLQTYRFIVEEDLARRTLVPVLSEWDGASRPFSLLYPAQRHMPLRVRVTIEFLLASLAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=284, Percent_Identity=34.5070422535211, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=32.0689655172414, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=29.553264604811, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=27.681660899654, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787589, Length=275, Percent_Identity=29.0909090909091, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=30.7167235494881, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=29.3706293706294, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788706, Length=189, Percent_Identity=32.2751322751323, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789173, Length=191, Percent_Identity=32.9842931937173, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=35.8333333333333, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790011, Length=301, Percent_Identity=23.2558139534884, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790208, Length=178, Percent_Identity=33.7078651685393, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786448, Length=281, Percent_Identity=25.2669039145907, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=309, Percent_Identity=24.5954692556634, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33675; Mature: 33675

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRHFEDLKLGGIELFCTTAEQQSFTAAARAMGLTPAAVSRSISRLEARLGVQLLVRTTR
CCCCCCHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QVRLTEAGQAYFERCRQAITQLIDAEREVTGQQQAPTGLVRISLPTPYGHYRVLPLLPAF
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEECCHHH
RTRYPGITLDVQLTNRNIDFAAEGFDLAVRGRTLPDSGLVARKLEDAELVVVATPAYLSR
HHCCCCEEEEEEEECCCCCEEECCCEEEEECCCCCCCCCHHEECCCCCEEEEECCHHHHC
HGRPTTLESLQEHDCIQFLLPSTGQPTPWLFRQKGVDVEHLTRGGICCAEDILGTVTLAR
CCCCCHHHHHHHCCHHEEECCCCCCCCCCHHHHCCCCHHHHHCCCCEEHHHHHHEEEEEC
NGAGLLQTYRFIVEEDLARRTLVPVLSEWDGASRPFSLLYPAQRHMPLRVRVTIEFLLAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCEEEEEEHHHHHHH
LAA
HCC
>Mature Secondary Structure
MQRHFEDLKLGGIELFCTTAEQQSFTAAARAMGLTPAAVSRSISRLEARLGVQLLVRTTR
CCCCCCHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QVRLTEAGQAYFERCRQAITQLIDAEREVTGQQQAPTGLVRISLPTPYGHYRVLPLLPAF
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEECCHHH
RTRYPGITLDVQLTNRNIDFAAEGFDLAVRGRTLPDSGLVARKLEDAELVVVATPAYLSR
HHCCCCEEEEEEEECCCCCEEECCCEEEEECCCCCCCCCHHEECCCCCEEEEECCHHHHC
HGRPTTLESLQEHDCIQFLLPSTGQPTPWLFRQKGVDVEHLTRGGICCAEDILGTVTLAR
CCCCCHHHHHHHCCHHEEECCCCCCCCCCHHHHCCCCHHHHHCCCCEEHHHHHHEEEEEC
NGAGLLQTYRFIVEEDLARRTLVPVLSEWDGASRPFSLLYPAQRHMPLRVRVTIEFLLAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCEEEEEEHHHHHHH
LAA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]