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The map label for this gene is ltrA [H]

Identifier: 120611211

GI number: 120611211

Start: 2791317

End: 2792252

Strand: Direct

Name: ltrA [H]

Synonym: Aave_2542

Alternate gene names: 120611211

Gene position: 2791317-2792252 (Clockwise)

Preceding gene: 120611209

Following gene: 120611212

Centisome position: 52.15

GC content: 71.9

Gene sequence:

>936_bases
ATGCAAGACCTGAACGACATGCTGTATTTCGCCGAGGTGGTGGAGCGGGGCGGCTTCGCCGCCGCGGGCCGCGCGCTCGG
CATCCCCAAGTCCCGGTTGTCGCGCCGCGTATCCGAGCTGGAGGCGCAATTGGGCGTGCGCCTGCTGCAGCGCACGACCC
GCAAGCTGTCGCTCACCGAGATCGGCGAGTCCTACCTGCGCCACTGCCAGGCGGTACGGGAGGCCGCGCAGGCCGCCTCC
GATGCGGTGGCAGAGGTCCAGACGGAACCGCGCGGCACGGTGCGCGTGAGCTGTCCGGTCACGCTCGCCCAGACGGTGCT
GGGAGAGCTGATGCCGATCTTCCTGGAGCGCCATCCCCAGGTGCGGGTGGAGATGCAGGTCACGAACCGGGCCGTCGATC
TGGTGGAGGAGGGCGTGGACGTGGCCCTGCGCGTGCGGCCGAATCTCGACGACAGCGGCAGCATGGTCGTCAAGCGGCTG
GACGACGTGCTGCAGGTGCTGGTCGCCAGCCCGGCCCTGCTGGCCCGGCAGGGCACGCCAGCCACCCTCGCCGAACTGAG
CCGTCTGGACAGCATGGCGATGTCCGCGCCCGACGGCCGCACCGCCCTGCGCCTGGTCGGGCCCGACGGCCGCGAGGAAG
CCGTGCAGCTCACGCCGCGGTACGTGGCGGACGATCTGCTCACCCTCAAGTTCGCCGCGCTGGCCGGCACCGGCATGTGC
TGGCTGCCCGACTACATGTGCCAGGCGGAACTGGGCGAGGGGCGGCTGGTGCGCATCCTGCCCGGCTGGTCCACGCCGCG
CGGGGTGGTGCATGCGGTGTTCCCCTCGCGCCGCGGCCTGGCTCCGGCCGTGCGGCGTTTCCTGGATTTCCTGGGCGAGA
CCGTTCCGGGCCACAACGAAGTGGTCTGCCGGCGCGGCGGCACGCGAACCGCGTGA

Upstream 100 bases:

>100_bases
TGGCGTGGATTGGATTGTGCGGCGGTGTGGATGCATTGATAAGGCGGAGCATTTACGATAGATCGTTCCATCCATGAGAC
GATGGGCAGGAGCCCTGGCC

Downstream 100 bases:

>100_bases
TTTTCGGCGCGTTGCATTACACGCGCTTTACATGGCTGCCTTACACTGGCTTGTAACCGATCGGTCACTCCATGGACTCA
TCGGTAAATTACGTACGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQDLNDMLYFAEVVERGGFAAAGRALGIPKSRLSRRVSELEAQLGVRLLQRTTRKLSLTEIGESYLRHCQAVREAAQAAS
DAVAEVQTEPRGTVRVSCPVTLAQTVLGELMPIFLERHPQVRVEMQVTNRAVDLVEEGVDVALRVRPNLDDSGSMVVKRL
DDVLQVLVASPALLARQGTPATLAELSRLDSMAMSAPDGRTALRLVGPDGREEAVQLTPRYVADDLLTLKFAALAGTGMC
WLPDYMCQAELGEGRLVRILPGWSTPRGVVHAVFPSRRGLAPAVRRFLDFLGETVPGHNEVVCRRGGTRTA

Sequences:

>Translated_311_residues
MQDLNDMLYFAEVVERGGFAAAGRALGIPKSRLSRRVSELEAQLGVRLLQRTTRKLSLTEIGESYLRHCQAVREAAQAAS
DAVAEVQTEPRGTVRVSCPVTLAQTVLGELMPIFLERHPQVRVEMQVTNRAVDLVEEGVDVALRVRPNLDDSGSMVVKRL
DDVLQVLVASPALLARQGTPATLAELSRLDSMAMSAPDGRTALRLVGPDGREEAVQLTPRYVADDLLTLKFAALAGTGMC
WLPDYMCQAELGEGRLVRILPGWSTPRGVVHAVFPSRRGLAPAVRRFLDFLGETVPGHNEVVCRRGGTRTA
>Mature_311_residues
MQDLNDMLYFAEVVERGGFAAAGRALGIPKSRLSRRVSELEAQLGVRLLQRTTRKLSLTEIGESYLRHCQAVREAAQAAS
DAVAEVQTEPRGTVRVSCPVTLAQTVLGELMPIFLERHPQVRVEMQVTNRAVDLVEEGVDVALRVRPNLDDSGSMVVKRL
DDVLQVLVASPALLARQGTPATLAELSRLDSMAMSAPDGRTALRLVGPDGREEAVQLTPRYVADDLLTLKFAALAGTGMC
WLPDYMCQAELGEGRLVRILPGWSTPRGVVHAVFPSRRGLAPAVRRFLDFLGETVPGHNEVVCRRGGTRTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=33.7837837837838, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=32.312925170068, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=28.135593220339, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=27.9863481228669, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=26.510067114094, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=28.8590604026846, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789440, Length=265, Percent_Identity=24.1509433962264, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082132, Length=303, Percent_Identity=23.7623762376238, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=118, Percent_Identity=31.3559322033898, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=202, Percent_Identity=25.2475247524752, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789173, Length=259, Percent_Identity=28.1853281853282, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33886; Mature: 33886

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLNDMLYFAEVVERGGFAAAGRALGIPKSRLSRRVSELEAQLGVRLLQRTTRKLSLTE
CCCHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGESYLRHCQAVREAAQAASDAVAEVQTEPRGTVRVSCPVTLAQTVLGELMPIFLERHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCC
VRVEMQVTNRAVDLVEEGVDVALRVRPNLDDSGSMVVKRLDDVLQVLVASPALLARQGTP
EEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCC
ATLAELSRLDSMAMSAPDGRTALRLVGPDGREEAVQLTPRYVADDLLTLKFAALAGTGMC
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCC
WLPDYMCQAELGEGRLVRILPGWSTPRGVVHAVFPSRRGLAPAVRRFLDFLGETVPGHNE
CCCHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCC
VVCRRGGTRTA
EEEECCCCCCC
>Mature Secondary Structure
MQDLNDMLYFAEVVERGGFAAAGRALGIPKSRLSRRVSELEAQLGVRLLQRTTRKLSLTE
CCCHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGESYLRHCQAVREAAQAASDAVAEVQTEPRGTVRVSCPVTLAQTVLGELMPIFLERHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCC
VRVEMQVTNRAVDLVEEGVDVALRVRPNLDDSGSMVVKRLDDVLQVLVASPALLARQGTP
EEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCC
ATLAELSRLDSMAMSAPDGRTALRLVGPDGREEAVQLTPRYVADDLLTLKFAALAGTGMC
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCC
WLPDYMCQAELGEGRLVRILPGWSTPRGVVHAVFPSRRGLAPAVRRFLDFLGETVPGHNE
CCCHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCC
VVCRRGGTRTA
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]