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The map label for this gene is ttdR [H]

Identifier: 120611202

GI number: 120611202

Start: 2780522

End: 2781544

Strand: Reverse

Name: ttdR [H]

Synonym: Aave_2533

Alternate gene names: 120611202

Gene position: 2781544-2780522 (Counterclockwise)

Preceding gene: 120611210

Following gene: 120611201

Centisome position: 51.96

GC content: 72.24

Gene sequence:

>1023_bases
ATGACCAATCCGTCCCTGCTCATGAACGGTGCCGACCGCATCGAGTTGCTGCAGACCTTCGTCCGCATCGTGGACAGCGG
CAGCCTGTCCGCAGCGGCGCGGCAGCTCGGCACCACCCAGCCCACCGTCAGCCGGCGCCTGCAGGCGCTGGAGCGCGGCA
TGGGCCTGCGGTTGCTGCAGCGCTCCACGCACGGCATGAAGCTCACGGAAGATGGCGAGCGCTGCTTCGCCCATGCCAGG
GAACTGCTGGCGCAGTGGCAGGCCATGGAGTCGGACCTGCGCGGCGCGCACGACACGCCCCGGGGCCTGCTGCGCGTGCA
GGCCCCGCACGCGTTCGGACAGGACCAGCTGATAGCGCCGCTGGCGGCCTTCCTGCGCCGCTATCCCGAGGTATCGGTCG
AATGGCTGCTGCACGACCGCCAGCCGGACTTCATCGCGGAGGGCATCGACTGCGCGATCCAGGTGGGGCCGGTGCGGGAT
CCGTCCGTCGTCGCCACGCACGTGGCCGAGGTGCCCCGCATCGTGGTGGCCTCGCCAGGCCTGCTGGAGGCGCACGGCGG
CGCGCCGCCGCACCCGCAGGACCTGGGCGCCCTGCCCTGGCTGGCCCTGCGCACCTATTACCTGCGCGAGGTGGAACTGC
ATCCGGAGGAAGGGCTGGCCACGGCACCCGCTGCGGCAGCGAAACCGGATGCCACCGCCGGACCGCAGGCCATCGCCATC
CGGCCGAGGATGGCCACCGACAGCCTGCATGCCCTGCGCAACGCGGCACTGTCGGGCCTGGGCGCAGCCCTCGTGTCCGC
CTGGGCGGTGCAGGACGACCTGCGCTCGGGCCGGCTGGTGCATGTCGTGCCAGGCTGGAGGGCGCAGCCCCTGCCCGTGC
ATCTGGTCTATCCGCCCACCCGCCACCCGCCGGCACGCCTGCGCGTCTTCCTGGAGGCGATGCGCGAAGCGATTCCGTCG
ATCGCCGGCATGCAGGCACGGCGCGTGGCACCATCCGGGCCATCCTTGCGACCACGGCGATGA

Upstream 100 bases:

>100_bases
GTCATAGGAATACGCCTGGGAAAGACAATGGCTGCAGTGTCCCCGCTCCTTAGGATATGCGGTAGCCTACCCGCGCGCAG
ATCAGATATACGCTACACGC

Downstream 100 bases:

>100_bases
GCGACACCCCCCCCCTCTCCCCTTCCGGATCTGGCCCCGCTGCGGGAGCGGATGGCCCACGCCAACCACGCCCCCGTGCG
CATCCTCATGGTCTGCATGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTNPSLLMNGADRIELLQTFVRIVDSGSLSAAARQLGTTQPTVSRRLQALERGMGLRLLQRSTHGMKLTEDGERCFAHAR
ELLAQWQAMESDLRGAHDTPRGLLRVQAPHAFGQDQLIAPLAAFLRRYPEVSVEWLLHDRQPDFIAEGIDCAIQVGPVRD
PSVVATHVAEVPRIVVASPGLLEAHGGAPPHPQDLGALPWLALRTYYLREVELHPEEGLATAPAAAAKPDATAGPQAIAI
RPRMATDSLHALRNAALSGLGAALVSAWAVQDDLRSGRLVHVVPGWRAQPLPVHLVYPPTRHPPARLRVFLEAMREAIPS
IAGMQARRVAPSGPSLRPRR

Sequences:

>Translated_340_residues
MTNPSLLMNGADRIELLQTFVRIVDSGSLSAAARQLGTTQPTVSRRLQALERGMGLRLLQRSTHGMKLTEDGERCFAHAR
ELLAQWQAMESDLRGAHDTPRGLLRVQAPHAFGQDQLIAPLAAFLRRYPEVSVEWLLHDRQPDFIAEGIDCAIQVGPVRD
PSVVATHVAEVPRIVVASPGLLEAHGGAPPHPQDLGALPWLALRTYYLREVELHPEEGLATAPAAAAKPDATAGPQAIAI
RPRMATDSLHALRNAALSGLGAALVSAWAVQDDLRSGRLVHVVPGWRAQPLPVHLVYPPTRHPPARLRVFLEAMREAIPS
IAGMQARRVAPSGPSLRPRR
>Mature_339_residues
TNPSLLMNGADRIELLQTFVRIVDSGSLSAAARQLGTTQPTVSRRLQALERGMGLRLLQRSTHGMKLTEDGERCFAHARE
LLAQWQAMESDLRGAHDTPRGLLRVQAPHAFGQDQLIAPLAAFLRRYPEVSVEWLLHDRQPDFIAEGIDCAIQVGPVRDP
SVVATHVAEVPRIVVASPGLLEAHGGAPPHPQDLGALPWLALRTYYLREVELHPEEGLATAPAAAAKPDATAGPQAIAIR
PRMATDSLHALRNAALSGLGAALVSAWAVQDDLRSGRLVHVVPGWRAQPLPVHLVYPPTRHPPARLRVFLEAMREAIPSI
AGMQARRVAPSGPSLRPRR

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=32.2147651006711, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=29.9003322259136, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081978, Length=309, Percent_Identity=29.4498381877023, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789639, Length=313, Percent_Identity=27.7955271565495, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786401, Length=318, Percent_Identity=30.188679245283, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787128, Length=308, Percent_Identity=23.7012987012987, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787589, Length=302, Percent_Identity=21.523178807947, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789173, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786713, Length=116, Percent_Identity=33.6206896551724, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787601, Length=121, Percent_Identity=28.099173553719, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788748, Length=198, Percent_Identity=29.2929292929293, Blast_Score=61, Evalue=9e-11,
Organism=Escherichia coli, GI157672245, Length=153, Percent_Identity=28.1045751633987, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36937; Mature: 36806

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPSLLMNGADRIELLQTFVRIVDSGSLSAAARQLGTTQPTVSRRLQALERGMGLRLLQ
CCCCCCEECCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHH
RSTHGMKLTEDGERCFAHARELLAQWQAMESDLRGAHDTPRGLLRVQAPHAFGQDQLIAP
HCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHH
LAAFLRRYPEVSVEWLLHDRQPDFIAEGIDCAIQVGPVRDPSVVATHVAEVPRIVVASPG
HHHHHHHCCCCEEEEEEECCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHCCEEEEECCC
LLEAHGGAPPHPQDLGALPWLALRTYYLREVELHPEEGLATAPAAAAKPDATAGPQAIAI
CEECCCCCCCCCHHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
RPRMATDSLHALRNAALSGLGAALVSAWAVQDDLRSGRLVHVVPGWRAQPLPVHLVYPPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCC
RHPPARLRVFLEAMREAIPSIAGMQARRVAPSGPSLRPRR
CCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TNPSLLMNGADRIELLQTFVRIVDSGSLSAAARQLGTTQPTVSRRLQALERGMGLRLLQ
CCCCCEECCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHH
RSTHGMKLTEDGERCFAHARELLAQWQAMESDLRGAHDTPRGLLRVQAPHAFGQDQLIAP
HCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHH
LAAFLRRYPEVSVEWLLHDRQPDFIAEGIDCAIQVGPVRDPSVVATHVAEVPRIVVASPG
HHHHHHHCCCCEEEEEEECCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHCCEEEEECCC
LLEAHGGAPPHPQDLGALPWLALRTYYLREVELHPEEGLATAPAAAAKPDATAGPQAIAI
CEECCCCCCCCCHHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
RPRMATDSLHALRNAALSGLGAALVSAWAVQDDLRSGRLVHVVPGWRAQPLPVHLVYPPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCC
RHPPARLRVFLEAMREAIPSIAGMQARRVAPSGPSLRPRR
CCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]