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The map label for this gene is 120611189

Identifier: 120611189

GI number: 120611189

Start: 2763516

End: 2764643

Strand: Reverse

Name: 120611189

Synonym: Aave_2520

Alternate gene names: NA

Gene position: 2764643-2763516 (Counterclockwise)

Preceding gene: 120611190

Following gene: 120611188

Centisome position: 51.65

GC content: 67.73

Gene sequence:

>1128_bases
ATGGCCGAGAAGAAAACCCGAACCTCCCGCTCCCGCACCGCCTCCGCGCCCCATGACGCGCCCTCGCGCGCCGCCACGGC
CACGGGCGGGCAGGCCCCTACGTCCACCCGCGCGCTCTGGAAGGGCGCGATCAGCTTCGGCCTGGTCCATGTGCCCGTGG
GCCTGTATTCGGCCACGCAGGACAGTGGCATCGATTTCGACTGGCTCGACAAGCGCAGCATGGACCCCGTCGGCTACAAG
CGCATCAACAAGAAGACCGGCAAGGAAATCACGGCGGAGAACATCGTCAAGGGCGTGGAGTACGAAGATGGCCGCTACGT
GGTGCTCACGCCCGAGGAGATCGCGCAGGCCTACCCCAAGACCACCCAGACCATCGAGATCGAGGCCTTCCTGGATGCCG
ACGAGATCCCGTTCGTCTATCTGGAACGCCCCTATTACACGGCACCGCTGCCCCGCGGCGAGAAGGTCTATGCCCTGCTG
CGCGAGGCGCTCAAGGCGAGCCACCGCGTGGGCGTGGGCAAGGTGGTGATCCAGACCAAGCAGCACCTGGCGGTGCTCAT
TCCCTGCGGACGCGCGCTGGTGCTCAACCTGCTGCGCTGGGGCGGCGAGATACGCTCCTTCCAGGAACTGAACCTGCCCC
CTGCCGGAGGCAAGGCCGTGGGGCTCAAGGATGCCGAGATGCGCATGGCGCGGCAGCTGATCGACGACATGACGCAGGAC
TGGGATGCGGACCAGTTCCGCAACTCGTTCTCCGAAGAGATCATGAAACTCGTGGAAGCGCGCGCCCAGGCCGGCGACAT
CGCCGAAGTCGAACCGCTGGAGGCACCGTCGGACGCTGGCGGCGCGGACGTGGTGGACCTCACCGCCCTGCTGCGCCGCA
GCCTCGAAGGCGGACGGCGCAAGGCTGCAGCGGATACGGACGAAAAGGGAGAGGACGACGGCGAGGATGAAGCGGAAGGT
GGCGCGAAGGGAAGGAAAACCTCGAGCGTGCGGCACCTGCCCGCCAAGTCGGCCAAGGCACGCACCGCATCCGACGGCGG
CGCGAAGGGCAAGGCCAAGGCCCCCGCGAAGCGCGCGACCGCCAAGTCCTCCGCGAAAAGCGCCCCTGCGGGCCGCAAGG
CCGCCTGA

Upstream 100 bases:

>100_bases
CGGCCCGCGTCCTACAGCACGCGCCCCGCGGCCGGGCTAACGTCGTCTGCACCATGGCACCGTCGGCGAGCCGCCGCCGC
GCGCCGCAAGGAGAGTCCGC

Downstream 100 bases:

>100_bases
GCCCGCACGCCATGGCACGACGCTCCAGGACCTCCGGCACTGCGCAGGAAGCGCCGCGGAAAGCGCCGCAAAAGGCGCCA
CCGGACGCCCTCGCAGACTA

Product: Ku domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAEKKTRTSRSRTASAPHDAPSRAATATGGQAPTSTRALWKGAISFGLVHVPVGLYSATQDSGIDFDWLDKRSMDPVGYK
RINKKTGKEITAENIVKGVEYEDGRYVVLTPEEIAQAYPKTTQTIEIEAFLDADEIPFVYLERPYYTAPLPRGEKVYALL
REALKASHRVGVGKVVIQTKQHLAVLIPCGRALVLNLLRWGGEIRSFQELNLPPAGGKAVGLKDAEMRMARQLIDDMTQD
WDADQFRNSFSEEIMKLVEARAQAGDIAEVEPLEAPSDAGGADVVDLTALLRRSLEGGRRKAAADTDEKGEDDGEDEAEG
GAKGRKTSSVRHLPAKSAKARTASDGGAKGKAKAPAKRATAKSSAKSAPAGRKAA

Sequences:

>Translated_375_residues
MAEKKTRTSRSRTASAPHDAPSRAATATGGQAPTSTRALWKGAISFGLVHVPVGLYSATQDSGIDFDWLDKRSMDPVGYK
RINKKTGKEITAENIVKGVEYEDGRYVVLTPEEIAQAYPKTTQTIEIEAFLDADEIPFVYLERPYYTAPLPRGEKVYALL
REALKASHRVGVGKVVIQTKQHLAVLIPCGRALVLNLLRWGGEIRSFQELNLPPAGGKAVGLKDAEMRMARQLIDDMTQD
WDADQFRNSFSEEIMKLVEARAQAGDIAEVEPLEAPSDAGGADVVDLTALLRRSLEGGRRKAAADTDEKGEDDGEDEAEG
GAKGRKTSSVRHLPAKSAKARTASDGGAKGKAKAPAKRATAKSSAKSAPAGRKAA
>Mature_374_residues
AEKKTRTSRSRTASAPHDAPSRAATATGGQAPTSTRALWKGAISFGLVHVPVGLYSATQDSGIDFDWLDKRSMDPVGYKR
INKKTGKEITAENIVKGVEYEDGRYVVLTPEEIAQAYPKTTQTIEIEAFLDADEIPFVYLERPYYTAPLPRGEKVYALLR
EALKASHRVGVGKVVIQTKQHLAVLIPCGRALVLNLLRWGGEIRSFQELNLPPAGGKAVGLKDAEMRMARQLIDDMTQDW
DADQFRNSFSEEIMKLVEARAQAGDIAEVEPLEAPSDAGGADVVDLTALLRRSLEGGRRKAAADTDEKGEDDGEDEAEGG
AKGRKTSSVRHLPAKSAKARTASDGGAKGKAKAPAKRATAKSSAKSAPAGRKAA

Specific function: Could be involved in DNA repair [H]

COG id: COG1273

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ku domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006164
- InterPro:   IPR009187
- InterPro:   IPR016194 [H]

Pfam domain/function: PF02735 Ku [H]

EC number: NA

Molecular weight: Translated: 40353; Mature: 40222

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKTRTSRSRTASAPHDAPSRAATATGGQAPTSTRALWKGAISFGLVHVPVGLYSATQ
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCC
DSGIDFDWLDKRSMDPVGYKRINKKTGKEITAENIVKGVEYEDGRYVVLTPEEIAQAYPK
CCCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCEECCCCEEEECHHHHHHHCCC
TTQTIEIEAFLDADEIPFVYLERPYYTAPLPRGEKVYALLREALKASHRVGVGKVVIQTK
CCCEEEEEEEECCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
QHLAVLIPCGRALVLNLLRWGGEIRSFQELNLPPAGGKAVGLKDAEMRMARQLIDDMTQD
CCEEEEECCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHCC
WDADQFRNSFSEEIMKLVEARAQAGDIAEVEPLEAPSDAGGADVVDLTALLRRSLEGGRR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
KAAADTDEKGEDDGEDEAEGGAKGRKTSSVRHLPAKSAKARTASDGGAKGKAKAPAKRAT
HCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
AKSSAKSAPAGRKAA
HHHHHCCCCCCCCCC
>Mature Secondary Structure 
AEKKTRTSRSRTASAPHDAPSRAATATGGQAPTSTRALWKGAISFGLVHVPVGLYSATQ
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCC
DSGIDFDWLDKRSMDPVGYKRINKKTGKEITAENIVKGVEYEDGRYVVLTPEEIAQAYPK
CCCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCEECCCCEEEECHHHHHHHCCC
TTQTIEIEAFLDADEIPFVYLERPYYTAPLPRGEKVYALLREALKASHRVGVGKVVIQTK
CCCEEEEEEEECCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
QHLAVLIPCGRALVLNLLRWGGEIRSFQELNLPPAGGKAVGLKDAEMRMARQLIDDMTQD
CCEEEEECCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHCC
WDADQFRNSFSEEIMKLVEARAQAGDIAEVEPLEAPSDAGGADVVDLTALLRRSLEGGRR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
KAAADTDEKGEDDGEDEAEGGAKGRKTSSVRHLPAKSAKARTASDGGAKGKAKAPAKRAT
HCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
AKSSAKSAPAGRKAA
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]