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The map label for this gene is 120611185

Identifier: 120611185

GI number: 120611185

Start: 2758419

End: 2758886

Strand: Direct

Name: 120611185

Synonym: Aave_2516

Alternate gene names: NA

Gene position: 2758419-2758886 (Clockwise)

Preceding gene: 120611184

Following gene: 120611186

Centisome position: 51.53

GC content: 68.38

Gene sequence:

>468_bases
ATGAACAATGCTCGCCCCTTCAAGGTTCTCGGCATCCAGCAGATCGCCATCGGCGGCACCGACAAGCAGCGGCTGAAGAC
GCTCTGGGTGGACATGCTGGGCCTGCCGCAGACCGGCACGTTCCGCAGCGAGCGCGAGAACGTGGACGAGGACATTCTCT
CGATGGGGCAGGGCGCCCATGCCGTGGAGGTGGACCTGATGCAGCCGCTCGACATCGACCGCAAGCCCGCCGTGCACGCC
ACGCCGCTGAACCACGTGGGCCTGTGGATCGACGACCTGCCGCGTGCCGTGGAATGGCTCACGGCGCGGGGCGTGCGCTT
CGCGCCGGGCGGCATCCGCAAAGGTGCGGCGGGGCACGACATCACGTTCCTGCATCCCCGGGGCAACGAGGAGTTTCCCA
TCGCGGGCGAAGGCGTGCTGATCGAACTGGTGCAGGCACCGCCGGAGGTGATCGCCGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
TTTGGATATTGCCTAGTATTTTTATGTGGTCTACCGCAAATAGGTTGGAAAAAGCTTTGGCAGACGGAAAATTTTCTGAG
TCTCTTATCATCAAAAAACC

Downstream 100 bases:

>100_bases
CGCGGGCCCGGCCTTCACGGCCCTGGTGGACGGTATGGTGACGGGCAGGGTGCAATGTTGCCCGCCCCTGCGACAAAGGA
CTCTGTGTTCCCCATGCCCC

Product: lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: Methylmalonyl-CoA Epimerase; Glyoxalase/Bleomycin Resistance Protein/Dioxygenase

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MNNARPFKVLGIQQIAIGGTDKQRLKTLWVDMLGLPQTGTFRSERENVDEDILSMGQGAHAVEVDLMQPLDIDRKPAVHA
TPLNHVGLWIDDLPRAVEWLTARGVRFAPGGIRKGAAGHDITFLHPRGNEEFPIAGEGVLIELVQAPPEVIAALG

Sequences:

>Translated_155_residues
MNNARPFKVLGIQQIAIGGTDKQRLKTLWVDMLGLPQTGTFRSERENVDEDILSMGQGAHAVEVDLMQPLDIDRKPAVHA
TPLNHVGLWIDDLPRAVEWLTARGVRFAPGGIRKGAAGHDITFLHPRGNEEFPIAGEGVLIELVQAPPEVIAALG
>Mature_155_residues
MNNARPFKVLGIQQIAIGGTDKQRLKTLWVDMLGLPQTGTFRSERENVDEDILSMGQGAHAVEVDLMQPLDIDRKPAVHA
TPLNHVGLWIDDLPRAVEWLTARGVRFAPGGIRKGAAGHDITFLHPRGNEEFPIAGEGVLIELVQAPPEVIAALG

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5

Molecular weight: Translated: 16867; Mature: 16867

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNARPFKVLGIQQIAIGGTDKQRLKTLWVDMLGLPQTGTFRSERENVDEDILSMGQGAH
CCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHCCCCE
AVEVDLMQPLDIDRKPAVHATPLNHVGLWIDDLPRAVEWLTARGVRFAPGGIRKGAAGHD
EEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCC
ITFLHPRGNEEFPIAGEGVLIELVQAPPEVIAALG
EEEECCCCCCCCCCCCCCEEEEEECCCHHHHHCCC
>Mature Secondary Structure
MNNARPFKVLGIQQIAIGGTDKQRLKTLWVDMLGLPQTGTFRSERENVDEDILSMGQGAH
CCCCCCEEEECEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHCCCCE
AVEVDLMQPLDIDRKPAVHATPLNHVGLWIDDLPRAVEWLTARGVRFAPGGIRKGAAGHD
EEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCC
ITFLHPRGNEEFPIAGEGVLIELVQAPPEVIAALG
EEEECCCCCCCCCCCCCCEEEEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA