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The map label for this gene is nreC [H]

Identifier: 120611166

GI number: 120611166

Start: 2735547

End: 2736236

Strand: Direct

Name: nreC [H]

Synonym: Aave_2497

Alternate gene names: 120611166

Gene position: 2735547-2736236 (Clockwise)

Preceding gene: 120611165

Following gene: 120611170

Centisome position: 51.11

GC content: 65.65

Gene sequence:

>690_bases
ATGTCTCTGTCTCCTTTTTCGCGCCTCCATCCGGCCTGCTATGCGCTGGTCGTCGATGACCATCCACTCGTCGCACAGGG
CATGGCCGATTTTCTGGGCCTGCACGCCGCTGTCGCCGAGACACGCCATGCCTTCGACGCCACCAGCGCGTTGCGCATCG
TTGCCGCGCACGGCCCCCCCATGCTGGCTCTCGTGGATTTCTGGCTCGCCGAGGGCGCCTCGACCTCGTTCATCGCCAGC
CTCGTGGCGATGTCTCCGGGGACCCGTGTGCTGGTGACGAGCGCCGACCCGCATCCGGCGATTGCGTTGAAGGCCCGCGC
CAGCGGTGCCCATGGGTTCGTGCACAAGGGCGATCCCCCCGAGACCTACCATGCGGCCGTGACATCGGTGCTTCGTGGCC
AGGTCTGGTTCGATGCGAATGCGACAGTATTGCCCTCCCGATCTTCGGCCGGGTGCATGGCGCCTCGCGAGATCCGCCTG
GCGCCTGCCGACATCGGCCTGACGCCACGGCAGGGTGAAATCCTCGCGCTGGTCCTGGACGGTCTGCCGAACAAGCCGAT
TGCTTCCTCGCTTCACCTCTCGGAGCACACCGTGAAGGAACATCTCACGGCGATCCTGCAGAAGCTCGAGGCCCGCAACC
GTGTGGAACTCATCGCCAAGTTGCGCGGTGTTCGCATCGATGGCGCCTGA

Upstream 100 bases:

>100_bases
GGAAAGGGTTTTTCATCGGAAATCAAGTGGCGGGCGGTTACGCTCTGCCCAACTGTCGCATTGCATTTTGTCGATTCGGC
TGCACTGGCGAATCGTCTCA

Downstream 100 bases:

>100_bases
ACCGCGCGGGGTGGCGGAAAGTGCGCGGCGGGTGAGGTGTCCGGGGGGCAGGCCGGGTCTGCCGTGATTTACCGGAAGGT
TTGCCCGAGCCCCAATCCTC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSLSPFSRLHPACYALVVDDHPLVAQGMADFLGLHAAVAETRHAFDATSALRIVAAHGPPMLALVDFWLAEGASTSFIAS
LVAMSPGTRVLVTSADPHPAIALKARASGAHGFVHKGDPPETYHAAVTSVLRGQVWFDANATVLPSRSSAGCMAPREIRL
APADIGLTPRQGEILALVLDGLPNKPIASSLHLSEHTVKEHLTAILQKLEARNRVELIAKLRGVRIDGA

Sequences:

>Translated_229_residues
MSLSPFSRLHPACYALVVDDHPLVAQGMADFLGLHAAVAETRHAFDATSALRIVAAHGPPMLALVDFWLAEGASTSFIAS
LVAMSPGTRVLVTSADPHPAIALKARASGAHGFVHKGDPPETYHAAVTSVLRGQVWFDANATVLPSRSSAGCMAPREIRL
APADIGLTPRQGEILALVLDGLPNKPIASSLHLSEHTVKEHLTAILQKLEARNRVELIAKLRGVRIDGA
>Mature_228_residues
SLSPFSRLHPACYALVVDDHPLVAQGMADFLGLHAAVAETRHAFDATSALRIVAAHGPPMLALVDFWLAEGASTSFIASL
VAMSPGTRVLVTSADPHPAIALKARASGAHGFVHKGDPPETYHAAVTSVLRGQVWFDANATVLPSRSSAGCMAPREIRLA
PADIGLTPRQGEILALVLDGLPNKPIASSLHLSEHTVKEHLTAILQKLEARNRVELIAKLRGVRIDGA

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=202, Percent_Identity=27.2277227722772, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24210; Mature: 24079

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSPFSRLHPACYALVVDDHPLVAQGMADFLGLHAAVAETRHAFDATSALRIVAAHGPP
CCCCCCHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEECCCC
MLALVDFWLAEGASTSFIASLVAMSPGTRVLVTSADPHPAIALKARASGAHGFVHKGDPP
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCC
ETYHAAVTSVLRGQVWFDANATVLPSRSSAGCMAPREIRLAPADIGLTPRQGEILALVLD
HHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEC
GLPNKPIASSLHLSEHTVKEHLTAILQKLEARNRVELIAKLRGVRIDGA
CCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCEEECCC
>Mature Secondary Structure 
SLSPFSRLHPACYALVVDDHPLVAQGMADFLGLHAAVAETRHAFDATSALRIVAAHGPP
CCCCCHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEECCCC
MLALVDFWLAEGASTSFIASLVAMSPGTRVLVTSADPHPAIALKARASGAHGFVHKGDPP
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCC
ETYHAAVTSVLRGQVWFDANATVLPSRSSAGCMAPREIRLAPADIGLTPRQGEILALVLD
HHHHHHHHHHHHCCEEECCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEC
GLPNKPIASSLHLSEHTVKEHLTAILQKLEARNRVELIAKLRGVRIDGA
CCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]