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The map label for this gene is insF1 [C]

Identifier: 120611069

GI number: 120611069

Start: 2619924

End: 2620781

Strand: Direct

Name: insF1 [C]

Synonym: Aave_2398

Alternate gene names: 120611069

Gene position: 2619924-2620781 (Clockwise)

Preceding gene: 120611068

Following gene: 120611081

Centisome position: 48.95

GC content: 68.18

Gene sequence:

>858_bases
ATGTGCCGGGTGCTGGGCGTGTCCCACAGCGGCTTCTACGACTGGCGGCACCGAGCGCCAAGCCAGCGCGCGATGGAGGA
CATGGTGCTCACCGAGCGGATCAGGCAGGTGCACGCCGAGTCCCGCGAGACCTACGGCCAGCCACGCGTGCGGGCCGAGT
TGGCCGCACAGGGCGTGCGCGTCGCAGGCAAGCGGATCGCCCGCCTCATGCGCCAGGCAGGCCTGCAGGGGATCAGCAAA
CGACGGGCGACCACGGTGACCACGCGGCGTGACCCACGCGAGCGTCCAGCGGCGGACCTCGTGATGCGACGCTTCCGCGC
CGAGCGAGCGAACCAGCTGTGGGTGGCCGACATGACCTATGTGCCGACGTGGGCAGGCTTCGTCTACCTGGCGGTGGTGA
TGGACGTCTTCAGCCGGCGCATCGTCGGCTGGTCGATGGGAGAGCGCATGACCGCGCAACTCGTGCTGGCGGCGCTGAAC
ATGGCATTGGCCCGACGCAAGCCCCAGGGTGTCATCCACCACTCGGACCAGGGCAGCCAGTACACCAGCCTGGCGTTCGG
GCAACGCTGCGCCGAGATGGGTGTGCGCCCGTCGATGGGCAGTGTGGGTGACGCGTACGACAACGCCATGGCCGAGAGCT
TCTTCGCCACGCTCGAATGCGAGCTGATCGAGCGGCGCAGCTTCCGATCGAAGGCGGAGGCGAAGGCCGCGGTGTTCAGC
TACATCGAGGGCTGGTACAACCCGCGCCGACGCCACTCCGCGCTGAGCTACCACTCACCCGTGGAGTTCGAGCGCCGCGT
CGTCGCCGAGGCGTGTCAGGCAACGGAGATCAACGAGAGAGACCAAATCCCGGCTTGA

Upstream 100 bases:

>100_bases
TGGCAAAGGCTACGGCCTGGTTCGCCGCCAAGAGCGACAAGACGTTCACGCCGTCTTCGAACTCGTGAACGCGAACCAGG
CCGACTTCCCCGTTCGGACG

Downstream 100 bases:

>100_bases
GAATCAAGCCGATAACCGTCCGTGGAAGCGGGACAACTTCACTTATCTGTGCTCCAAGCCCCATGCCGCCCGCGGCCCTC
ATGGCGATGGACGTGGTACC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MCRVLGVSHSGFYDWRHRAPSQRAMEDMVLTERIRQVHAESRETYGQPRVRAELAAQGVRVAGKRIARLMRQAGLQGISK
RRATTVTTRRDPRERPAADLVMRRFRAERANQLWVADMTYVPTWAGFVYLAVVMDVFSRRIVGWSMGERMTAQLVLAALN
MALARRKPQGVIHHSDQGSQYTSLAFGQRCAEMGVRPSMGSVGDAYDNAMAESFFATLECELIERRSFRSKAEAKAAVFS
YIEGWYNPRRRHSALSYHSPVEFERRVVAEACQATEINERDQIPA

Sequences:

>Translated_285_residues
MCRVLGVSHSGFYDWRHRAPSQRAMEDMVLTERIRQVHAESRETYGQPRVRAELAAQGVRVAGKRIARLMRQAGLQGISK
RRATTVTTRRDPRERPAADLVMRRFRAERANQLWVADMTYVPTWAGFVYLAVVMDVFSRRIVGWSMGERMTAQLVLAALN
MALARRKPQGVIHHSDQGSQYTSLAFGQRCAEMGVRPSMGSVGDAYDNAMAESFFATLECELIERRSFRSKAEAKAAVFS
YIEGWYNPRRRHSALSYHSPVEFERRVVAEACQATEINERDQIPA
>Mature_285_residues
MCRVLGVSHSGFYDWRHRAPSQRAMEDMVLTERIRQVHAESRETYGQPRVRAELAAQGVRVAGKRIARLMRQAGLQGISK
RRATTVTTRRDPRERPAADLVMRRFRAERANQLWVADMTYVPTWAGFVYLAVVMDVFSRRIVGWSMGERMTAQLVLAALN
MALARRKPQGVIHHSDQGSQYTSLAFGQRCAEMGVRPSMGSVGDAYDNAMAESFFATLECELIERRSFRSKAEAKAAVFS
YIEGWYNPRRRHSALSYHSPVEFERRVVAEACQATEINERDQIPA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=232, Percent_Identity=41.3793103448276, Blast_Score=174, Evalue=6e-44,
Organism=Escherichia coli, GI1788405, Length=273, Percent_Identity=41.025641025641, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1787263, Length=273, Percent_Identity=41.025641025641, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1786753, Length=273, Percent_Identity=41.025641025641, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1786570, Length=273, Percent_Identity=41.025641025641, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1786490, Length=273, Percent_Identity=41.025641025641, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1789981, Length=235, Percent_Identity=31.9148936170213, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32445; Mature: 32445

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRVLGVSHSGFYDWRHRAPSQRAMEDMVLTERIRQVHAESRETYGQPRVRAELAAQGVR
CCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VAGKRIARLMRQAGLQGISKRRATTVTTRRDPRERPAADLVMRRFRAERANQLWVADMTY
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCHH
VPTWAGFVYLAVVMDVFSRRIVGWSMGERMTAQLVLAALNMALARRKPQGVIHHSDQGSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCH
YTSLAFGQRCAEMGVRPSMGSVGDAYDNAMAESFFATLECELIERRSFRSKAEAKAAVFS
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIEGWYNPRRRHSALSYHSPVEFERRVVAEACQATEINERDQIPA
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MCRVLGVSHSGFYDWRHRAPSQRAMEDMVLTERIRQVHAESRETYGQPRVRAELAAQGVR
CCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VAGKRIARLMRQAGLQGISKRRATTVTTRRDPRERPAADLVMRRFRAERANQLWVADMTY
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCHH
VPTWAGFVYLAVVMDVFSRRIVGWSMGERMTAQLVLAALNMALARRKPQGVIHHSDQGSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCH
YTSLAFGQRCAEMGVRPSMGSVGDAYDNAMAESFFATLECELIERRSFRSKAEAKAAVFS
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIEGWYNPRRRHSALSYHSPVEFERRVVAEACQATEINERDQIPA
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]