Click here to switch to the map view.

The map label for this gene is xylH [H]

Identifier: 120610926

GI number: 120610926

Start: 2477159

End: 2478391

Strand: Reverse

Name: xylH [H]

Synonym: Aave_2252

Alternate gene names: 120610926

Gene position: 2478391-2477159 (Counterclockwise)

Preceding gene: 120610927

Following gene: 120610925

Centisome position: 46.3

GC content: 67.88

Gene sequence:

>1233_bases
ATGTCTTCCATGACCTCCACGCCCAATACCTCCGCCCCCGCCGCCGCCTCCTCCGCCCAGCCCGCGCGCACCGGCCGCTC
GCCCCTGGAGCACGCCCGCCACCACCTGCGCGAATACGGCATGCTGATCACGCTGGTCGCGATCATGGGCTTCTTCCAGT
ACATGACCGACGGCACCCTGATGGAGCCGCTCAACCTCACCAACCTGCTGCTGCAGAACAGCTACATCGTCATCATGGCG
CTGGGCATGCTGCTGGTGATCGTGGCCGGCCACATCGACCTCTCGGTGGGATCGGTGAGCGGCTTCATCGGCGCGCTGGC
GGCCGTGCTCATGGTGCAGCACGGCTGGCACTTCGTCCCCGCCACGCTCGTCTGCCTGCTGTGCGGCGGCCTCATCGGCG
GGCTGCAGGGCTGGTTCGTGGCGTTCTCGCGCATTCCGTCGTTCATCGTCACCCTGGCCGGCATGCTGGTCTTCAAGGGC
CTGGCGCTGGCGCTGCTGGCGGGGCAGTCCGTGGGGCCGTTCCCCGAGGCCTTCCAGCGCCTCAGTTCCGGCTTCATTCC
CGACGTGTTCAGCATGCAAGGCCTGAAAGTGACGTCGCTGCTGCTGGGCACGGCCGGGGCGGCCGCCCTGGTGGTGGCGG
GCATCCGCGCCCGAGCCAACCGCGTGCGCCACGGCGTGCAGGTGGAGCCCGCCGCCTTCTTCATCGCCCGCAATGCGGTG
TTCACCGCGCTGCTCGTGTATCTCAGCTACCTGCTGGCCTCGTACAAGGGCCTGCCCAACGTGCTGATCGTGATGGCGCT
GCTGATCGTGCTGTTCGACTTCGTCGCCAGCCGCACCACCATCGGCCGCCGCATCTACGCCATGGGCGGCAACGAGAAGG
CCGCCAGGCTCTCGGGCATCAAGACCGAGCGCCTGTCGTTCTACGCCTTCGTGAACATGGGCGTGCTGGCGGCGCTCGCG
GGCCTGGTGTTCGCGGCGCGCCTCAACACCGCCACGCCCAAGGCCGGCCTGGGCTTCGAGCTGGACGTGATCGCGGCCTG
CTTCATCGGCGGGGCCTCGGCCTCGGGCGGCGTGGGCAAGGTCATGGGCGCGGTGATCGGCGCTTTCATCATGGGCGTGA
TGAACAACGGCATGTCGATCCTCGGCATCGGCATCGACTACCAGCAGGTCATCAAGGGCGTGGTGCTGCTGGCCGCCGTG
CTGGTGGACGTCTATCACAAGAACAAGGCCTGA

Upstream 100 bases:

>100_bases
CGCCTCTACGTGATGAACGAAGGCCGCTTCGTCGCAGAGATGCCCACGGCCCAGGCATCGCAGGAAAAGATCATGAGCGC
CATCGTGAAAGCCCACTGAC

Downstream 100 bases:

>100_bases
CCTCCTGACCAGGCCGCCCCCCGCAGCACTGACACCATGATGACCTCGGCCCCGCAAGCCCCCGACGCAGCGCCCGTGCT
GGAACTGGCGGGCATCCGCA

Product: inner-membrane translocator

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSSMTSTPNTSAPAAASSAQPARTGRSPLEHARHHLREYGMLITLVAIMGFFQYMTDGTLMEPLNLTNLLLQNSYIVIMA
LGMLLVIVAGHIDLSVGSVSGFIGALAAVLMVQHGWHFVPATLVCLLCGGLIGGLQGWFVAFSRIPSFIVTLAGMLVFKG
LALALLAGQSVGPFPEAFQRLSSGFIPDVFSMQGLKVTSLLLGTAGAAALVVAGIRARANRVRHGVQVEPAAFFIARNAV
FTALLVYLSYLLASYKGLPNVLIVMALLIVLFDFVASRTTIGRRIYAMGGNEKAARLSGIKTERLSFYAFVNMGVLAALA
GLVFAARLNTATPKAGLGFELDVIAACFIGGASASGGVGKVMGAVIGAFIMGVMNNGMSILGIGIDYQQVIKGVVLLAAV
LVDVYHKNKA

Sequences:

>Translated_410_residues
MSSMTSTPNTSAPAAASSAQPARTGRSPLEHARHHLREYGMLITLVAIMGFFQYMTDGTLMEPLNLTNLLLQNSYIVIMA
LGMLLVIVAGHIDLSVGSVSGFIGALAAVLMVQHGWHFVPATLVCLLCGGLIGGLQGWFVAFSRIPSFIVTLAGMLVFKG
LALALLAGQSVGPFPEAFQRLSSGFIPDVFSMQGLKVTSLLLGTAGAAALVVAGIRARANRVRHGVQVEPAAFFIARNAV
FTALLVYLSYLLASYKGLPNVLIVMALLIVLFDFVASRTTIGRRIYAMGGNEKAARLSGIKTERLSFYAFVNMGVLAALA
GLVFAARLNTATPKAGLGFELDVIAACFIGGASASGGVGKVMGAVIGAFIMGVMNNGMSILGIGIDYQQVIKGVVLLAAV
LVDVYHKNKA
>Mature_409_residues
SSMTSTPNTSAPAAASSAQPARTGRSPLEHARHHLREYGMLITLVAIMGFFQYMTDGTLMEPLNLTNLLLQNSYIVIMAL
GMLLVIVAGHIDLSVGSVSGFIGALAAVLMVQHGWHFVPATLVCLLCGGLIGGLQGWFVAFSRIPSFIVTLAGMLVFKGL
ALALLAGQSVGPFPEAFQRLSSGFIPDVFSMQGLKVTSLLLGTAGAAALVVAGIRARANRVRHGVQVEPAAFFIARNAVF
TALLVYLSYLLASYKGLPNVLIVMALLIVLFDFVASRTTIGRRIYAMGGNEKAARLSGIKTERLSFYAFVNMGVLAALAG
LVFAARLNTATPKAGLGFELDVIAACFIGGASASGGVGKVMGAVIGAFIMGVMNNGMSILGIGIDYQQVIKGVVLLAAVL
VDVYHKNKA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=402, Percent_Identity=39.3034825870647, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790191, Length=147, Percent_Identity=45.578231292517, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI145693152, Length=158, Percent_Identity=40.5063291139241, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1788896, Length=163, Percent_Identity=37.4233128834356, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1790524, Length=166, Percent_Identity=39.7590361445783, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787793, Length=328, Percent_Identity=28.0487804878049, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082395, Length=313, Percent_Identity=29.7124600638978, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788471, Length=144, Percent_Identity=40.9722222222222, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 42955; Mature: 42824

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSMTSTPNTSAPAAASSAQPARTGRSPLEHARHHLREYGMLITLVAIMGFFQYMTDGTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MEPLNLTNLLLQNSYIVIMALGMLLVIVAGHIDLSVGSVSGFIGALAAVLMVQHGWHFVP
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCHHH
ATLVCLLCGGLIGGLQGWFVAFSRIPSFIVTLAGMLVFKGLALALLAGQSVGPFPEAFQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LSSGFIPDVFSMQGLKVTSLLLGTAGAAALVVAGIRARANRVRHGVQVEPAAFFIARNAV
HHCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FTALLVYLSYLLASYKGLPNVLIVMALLIVLFDFVASRTTIGRRIYAMGGNEKAARLSGI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCC
KTERLSFYAFVNMGVLAALAGLVFAARLNTATPKAGLGFELDVIAACFIGGASASGGVGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHH
VMGAVIGAFIMGVMNNGMSILGIGIDYQQVIKGVVLLAAVLVDVYHKNKA
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSMTSTPNTSAPAAASSAQPARTGRSPLEHARHHLREYGMLITLVAIMGFFQYMTDGTL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MEPLNLTNLLLQNSYIVIMALGMLLVIVAGHIDLSVGSVSGFIGALAAVLMVQHGWHFVP
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCHHH
ATLVCLLCGGLIGGLQGWFVAFSRIPSFIVTLAGMLVFKGLALALLAGQSVGPFPEAFQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LSSGFIPDVFSMQGLKVTSLLLGTAGAAALVVAGIRARANRVRHGVQVEPAAFFIARNAV
HHCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FTALLVYLSYLLASYKGLPNVLIVMALLIVLFDFVASRTTIGRRIYAMGGNEKAARLSGI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCC
KTERLSFYAFVNMGVLAALAGLVFAARLNTATPKAGLGFELDVIAACFIGGASASGGVGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHH
VMGAVIGAFIMGVMNNGMSILGIGIDYQQVIKGVVLLAAVLVDVYHKNKA
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]