Click here to switch to the map view.

The map label for this gene is glxA [H]

Identifier: 120610870

GI number: 120610870

Start: 2417408

End: 2418412

Strand: Direct

Name: glxA [H]

Synonym: Aave_2196

Alternate gene names: 120610870

Gene position: 2417408-2418412 (Clockwise)

Preceding gene: 120610866

Following gene: 120610871

Centisome position: 45.16

GC content: 73.73

Gene sequence:

>1005_bases
ATGCACCCAGTCCAGCCCCTGTCCGTCCACATCGTCGTCTATCCGGGTTTCAAGGCGCTGGAGGCGGTGGGGCCGCTGTC
GGTATTCGACTATGCGAACGTGCACCTCGAGCGGCGCGGCCGGCCGCCCGGCTACGCCGTGTCGGTGGCGGCCCGCGCGC
GAGGCCCCGTGCGCTCCGACACGCTGATGGCCCTGGACGCCACCGAGGTGCTGTGCACCGCCGGCGATGCGGCGGCGCAC
GAAGCGATGCCTGACACGGCCCTGCTGGTCGGCGCCCGCCACATCGAGGCGGCCCTGGCCGATGCCCCGGAGATCGTGGC
CTGGGCTCGCACCGCGGCATCGCGCGTGCGCCGCATGGTGGCCCTGTGCTCCGGCAGCTTCTTCCTGGCCGCCGCCGGCC
TGCTCGACGGGCGCCGGGCCGCGACCCACTGGAGCGTGGCCGCCCGGCTGCAGGCACTGCACCCGGGCGTGGCGGTCGAT
CCGGATGCGATCTACGTGCGCGACGGCCACCTCTGGACTTCCGCGGGCGTCACCGCGGGCATCGACCTCGCGCTCGCCCT
GGTGGAAGAGGACTACGGCCATGCGCTCGCGCTGGAGGTGGCGCGCGACATGGTCATGTACCTCAAGCGGCCCGGCGGGC
AATCGCAGTTCAGCGTGCAGCTCGCCAGCCAGGCGACCACCCACCGCGGCATGCAGGACGTGCAGGCCTGGGCACTGGAG
CATTTGTCCGAGCCCCTCACCCTGCAGGTGCTGGCCGGGCGCGCCGCGATGAGCGAGCGCCACTTCCGCCGCGTGTTCGC
GCAGGAGACGGGGCGCAGCCCCTCGGCCTTCGTGGAGTCGGCCCGGCTGGAGGCCGCGCGCCGGCTGCTCGAATCCGACG
CCGCCCTGCCGCTCAAGACCGTGGCCGCGCGCGTCGGGCTGGGCTCGGAGCAGGCGCTGCGGCACCTGTTCCTGCGGCAC
CTGGGCATTCCGCCCCAGGCGTACCGCGAGCGCTTCGGCGATTGA

Upstream 100 bases:

>100_bases
GCGCTTTATAGAGCATGCCGGGCAGTCCTGGCCAGCGCGCGACCGCCGATGTCCGATGACCGGCCCGCTTTGTCCGATTG
AAAGCCTCTTCCCCCGCCGC

Downstream 100 bases:

>100_bases
ATCGCCACCATGCCATGAACGCATCGACTGCATTCCCCGACATCGGGATCCACACCCCCCGCTGCCTGCTGCGCCCCTTC
CGTGAGAGCGACCTGCCCGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MHPVQPLSVHIVVYPGFKALEAVGPLSVFDYANVHLERRGRPPGYAVSVAARARGPVRSDTLMALDATEVLCTAGDAAAH
EAMPDTALLVGARHIEAALADAPEIVAWARTAASRVRRMVALCSGSFFLAAAGLLDGRRAATHWSVAARLQALHPGVAVD
PDAIYVRDGHLWTSAGVTAGIDLALALVEEDYGHALALEVARDMVMYLKRPGGQSQFSVQLASQATTHRGMQDVQAWALE
HLSEPLTLQVLAGRAAMSERHFRRVFAQETGRSPSAFVESARLEAARRLLESDAALPLKTVAARVGLGSEQALRHLFLRH
LGIPPQAYRERFGD

Sequences:

>Translated_334_residues
MHPVQPLSVHIVVYPGFKALEAVGPLSVFDYANVHLERRGRPPGYAVSVAARARGPVRSDTLMALDATEVLCTAGDAAAH
EAMPDTALLVGARHIEAALADAPEIVAWARTAASRVRRMVALCSGSFFLAAAGLLDGRRAATHWSVAARLQALHPGVAVD
PDAIYVRDGHLWTSAGVTAGIDLALALVEEDYGHALALEVARDMVMYLKRPGGQSQFSVQLASQATTHRGMQDVQAWALE
HLSEPLTLQVLAGRAAMSERHFRRVFAQETGRSPSAFVESARLEAARRLLESDAALPLKTVAARVGLGSEQALRHLFLRH
LGIPPQAYRERFGD
>Mature_334_residues
MHPVQPLSVHIVVYPGFKALEAVGPLSVFDYANVHLERRGRPPGYAVSVAARARGPVRSDTLMALDATEVLCTAGDAAAH
EAMPDTALLVGARHIEAALADAPEIVAWARTAASRVRRMVALCSGSFFLAAAGLLDGRRAATHWSVAARLQALHPGVAVD
PDAIYVRDGHLWTSAGVTAGIDLALALVEEDYGHALALEVARDMVMYLKRPGGQSQFSVQLASQATTHRGMQDVQAWALE
HLSEPLTLQVLAGRAAMSERHFRRVFAQETGRSPSAFVESARLEAARRLLESDAALPLKTVAARVGLGSEQALRHLFLRH
LGIPPQAYRERFGD

Specific function: May Be A Transcriptional Activator Of Genes Involved In The Multiple Antibiotic Resistance (Mar) Phenotype. It Can Also Activate Genes Such As Soda, Zwf And Micf. [C]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081928, Length=94, Percent_Identity=34.0425531914894, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35917; Mature: 35917

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPVQPLSVHIVVYPGFKALEAVGPLSVFDYANVHLERRGRPPGYAVSVAARARGPVRSD
CCCCCCEEEEEEEECCHHHHHHCCCHHHHHHHHEEEECCCCCCCEEEEEEHHCCCCCCCC
TLMALDATEVLCTAGDAAAHEAMPDTALLVGARHIEAALADAPEIVAWARTAASRVRRMV
CEEEEEHHHHHEECCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ALCSGSFFLAAAGLLDGRRAATHWSVAARLQALHPGVAVDPDAIYVRDGHLWTSAGVTAG
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCEEECCCCHHH
IDLALALVEEDYGHALALEVARDMVMYLKRPGGQSQFSVQLASQATTHRGMQDVQAWALE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHH
HLSEPLTLQVLAGRAAMSERHFRRVFAQETGRSPSAFVESARLEAARRLLESDAALPLKT
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
VAARVGLGSEQALRHLFLRHLGIPPQAYRERFGD
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MHPVQPLSVHIVVYPGFKALEAVGPLSVFDYANVHLERRGRPPGYAVSVAARARGPVRSD
CCCCCCEEEEEEEECCHHHHHHCCCHHHHHHHHEEEECCCCCCCEEEEEEHHCCCCCCCC
TLMALDATEVLCTAGDAAAHEAMPDTALLVGARHIEAALADAPEIVAWARTAASRVRRMV
CEEEEEHHHHHEECCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ALCSGSFFLAAAGLLDGRRAATHWSVAARLQALHPGVAVDPDAIYVRDGHLWTSAGVTAG
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCEEECCCCHHH
IDLALALVEEDYGHALALEVARDMVMYLKRPGGQSQFSVQLASQATTHRGMQDVQAWALE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHH
HLSEPLTLQVLAGRAAMSERHFRRVFAQETGRSPSAFVESARLEAARRLLESDAALPLKT
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
VAARVGLGSEQALRHLFLRHLGIPPQAYRERFGD
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]