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The map label for this gene is cheA [H]

Identifier: 120610795

GI number: 120610795

Start: 2329493

End: 2331835

Strand: Direct

Name: cheA [H]

Synonym: Aave_2118

Alternate gene names: 120610795

Gene position: 2329493-2331835 (Clockwise)

Preceding gene: 120610794

Following gene: 120610796

Centisome position: 43.52

GC content: 72.0

Gene sequence:

>2343_bases
ATGACCGTCCGCTTGCGCATCACCCTGCTGATCGTTCTCGCCTTTCTCGCACTGTGCTCCGTCGGGGGCTTCGCGCTCTA
CCGTTCGGCGGAGGGGGCCCGCCAGGTCAAGCGGGTGACCGAGGGCGTCGTGCCCAGCGCCATCCATTCCGTGGAGCTCA
TGGGCCAGCTCAAGGACGTGCAGATGGCCGCGCTGGGCATGGTGTCCGCGAGCGACGCGGATGCCGCGCAGAAACTGCAC
GAGCAACTGGTGGAGCGCAAGGCGGTGCTGCAGAAGGCGCTGGACAAGCAGCTCCAGGAGGCCGACAGCGATGCGCAGCG
CGGCCTGGTGAAAGAGGCCGCCATGAGCCTGGAGAACTACTTCGCGGCCATCGACGACACGGCGCGCTTCAAGCTCGCCG
GCCAGCAGGACGCGGCCGAGGCCTTCATGGCCGCCACGGTGGACCAGTACCTGCGCGAGCAGGGCCAGATGATCGAGGCC
ATCCAGGTGGAGAAGCGCCGCACCAAGGACGAGGCCATCGGCTCGCTCAACGCCCAGCTGGAGCACACCACGACCACGCT
GCTGGCCGTGGCCGCCGTCGCCATCCTGGGCCTGGCCGCCGCGGGCTACCTGCTCTACCGCCAGATCGTGCGCCCCATCC
GCGAGATGGAGCTCAAGATGACCGAGATCGCCACGAGCCAGGATTTCTCGCACCGCGTGCCCGTCACCCGCATGGACGAA
ATCGGCCGCTCGCTCACCGCCTTCAACGCGATGGTGGAGAAGATCCAGGAAAGCTCCGAGCTGGTGCGCCGCAAGACGGC
CGACATCCAGGCCATGCTGCACACCATTCCCCAGGGCATCCTGACCCTGCAGGCCGGGCGCACCATCCACCCCGAATACT
CGGACCACCTCGCGCGCATCCTGGAAGAGGACGGCATCGCCGGCCGCACGCTCGATGCGCTGCTGTTCGACCGCTCCGAC
CTGAGTGCCGATGCGCGCGCCCAGGCCCTGGCTGCGATCGACGCCTGCATCGGCGAGGACGAACTCAACTTCTCGTTCAA
CGCCCACCTGCTGCCGCAGGAGTTGCAGGCGCGCTTCGGCGGCGACCGCGTGAAGGTGATCGAGCTGGGCTGGTCGCCCA
TCACGGCTGCCGACGGCACCGTGGAGCGCCTGCTGCTGAGCCTGCGCGACGTGACGGAGCTGCGCGAGCTGGCGCGGGAC
GCCCAGGCGCGCAAGGAGGAACTGGCCATGGTCGGCGAACTGCTGGGCGTGGCGGCGGACAGGTTCCGCGAATTCTCCGA
AAGCGCCGGGCGCCTGCTGCAGGACAACCGGGCGCTGCTCGGCTCCGCGGTGTCGCGGCCCGATGCGCGGCCGGACGCCC
TGGCGGCTCTGTTCCGCCACATGCATACCGTCAAGGGCAACGCCCGCACCTACGGCCTGCTGCGCATCGCCGATGCGGCG
CATGTGGCAGAGCAGCGCTACGCGGCGCTGCGGGACGACCCTGCCGGCTGGGGCGATGCCGTCCTGCAGTCCAGGCTGGA
GGCCGAACTCGAGGCGGTGGCCGGGGCCCTCCAGGCCTATGTGCGCGTGAATGACGGCACCCTGGGGCGCGGCGCGGGCC
ACGCGGTGGGCGATGCGCAGACGGTGCAGCTGCCGCGCGCCCGCATCGAGGAACTGTGCGCGCGCATCGGCGCCCTGGCG
CGGGACCCCGGCTGCACGCCGGCCCACCGCGCCGCGCTGGAGCGCATCGCCGCCGCGCTCGCCGACGCCGACGCGGCCGG
GCTGGACGAAGTGGTGGGCGGCGTGGCCGCCTCCCTGCCGGCGCTGGCCCGGGACCTGGGCAAGGAGGCCCCGGAGGTCG
TCCTGCAGTCCGGCGTGCCCGTGGCCGTGAAGCCGCAGGCCGCCGATGCGCTGCGCAATGCCTTCATGCACCTGCTGCGC
AATGCGCTGGACCATGGCATCGAGCCCGCGGCCGAGCGCGCAGCGCGCGGCAAGCCCGCCGCGGGCCGCATCCGCATCGG
CGCCGCGCTGGATGCGCAGGAACTGGAAATCCGGCTCGCCGACGACGGCCGCGGCCTCGACCTGGACCGCATCCAGGCCC
AGGCCCGCGCGCGGGGCCTGATCGCGGAAGACGCCACGCCCGCGCCCGGGGACGTCGCCCACCTGATCTTCGCGCCGGGC
TTTTCCACGGCCGGGGAGGTGACGGCCGTGTCGGGCCGCGGCGTGGGAATGGATGCGGTCAAGGCTTTCGTGGAATCGCT
GGGCGGCCGCATCCAGCTGGTGCTGGCCGGCGGCGCCCCGCGCGCGGCCACGCCGTTCGAAACCGTGCTGCGCCTGCCCG
CCCGCTGGGCGGTGGTGGCCTGA

Upstream 100 bases:

>100_bases
CTGACGGGCGGCCGGCACCTCCGCGGGGCTTTGTCATCCCCGCGCCATATGGCGATTCCATACTGGATGCATCTTGTTAC
ATGCGTGGATCGCCGCTGCC

Downstream 100 bases:

>100_bases
CGTAGGGGGTGGAGCGACATGATGGATGGCTGGATGCAGCTCCTGGCAGGCTGCGTGCTGGGTGGTGGATGTGTGGCGGC
CGCAGCGGCCTGGTTGTCCG

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MTVRLRITLLIVLAFLALCSVGGFALYRSAEGARQVKRVTEGVVPSAIHSVELMGQLKDVQMAALGMVSASDADAAQKLH
EQLVERKAVLQKALDKQLQEADSDAQRGLVKEAAMSLENYFAAIDDTARFKLAGQQDAAEAFMAATVDQYLREQGQMIEA
IQVEKRRTKDEAIGSLNAQLEHTTTTLLAVAAVAILGLAAAGYLLYRQIVRPIREMELKMTEIATSQDFSHRVPVTRMDE
IGRSLTAFNAMVEKIQESSELVRRKTADIQAMLHTIPQGILTLQAGRTIHPEYSDHLARILEEDGIAGRTLDALLFDRSD
LSADARAQALAAIDACIGEDELNFSFNAHLLPQELQARFGGDRVKVIELGWSPITAADGTVERLLLSLRDVTELRELARD
AQARKEELAMVGELLGVAADRFREFSESAGRLLQDNRALLGSAVSRPDARPDALAALFRHMHTVKGNARTYGLLRIADAA
HVAEQRYAALRDDPAGWGDAVLQSRLEAELEAVAGALQAYVRVNDGTLGRGAGHAVGDAQTVQLPRARIEELCARIGALA
RDPGCTPAHRAALERIAAALADADAAGLDEVVGGVAASLPALARDLGKEAPEVVLQSGVPVAVKPQAADALRNAFMHLLR
NALDHGIEPAAERAARGKPAAGRIRIGAALDAQELEIRLADDGRGLDLDRIQAQARARGLIAEDATPAPGDVAHLIFAPG
FSTAGEVTAVSGRGVGMDAVKAFVESLGGRIQLVLAGGAPRAATPFETVLRLPARWAVVA

Sequences:

>Translated_780_residues
MTVRLRITLLIVLAFLALCSVGGFALYRSAEGARQVKRVTEGVVPSAIHSVELMGQLKDVQMAALGMVSASDADAAQKLH
EQLVERKAVLQKALDKQLQEADSDAQRGLVKEAAMSLENYFAAIDDTARFKLAGQQDAAEAFMAATVDQYLREQGQMIEA
IQVEKRRTKDEAIGSLNAQLEHTTTTLLAVAAVAILGLAAAGYLLYRQIVRPIREMELKMTEIATSQDFSHRVPVTRMDE
IGRSLTAFNAMVEKIQESSELVRRKTADIQAMLHTIPQGILTLQAGRTIHPEYSDHLARILEEDGIAGRTLDALLFDRSD
LSADARAQALAAIDACIGEDELNFSFNAHLLPQELQARFGGDRVKVIELGWSPITAADGTVERLLLSLRDVTELRELARD
AQARKEELAMVGELLGVAADRFREFSESAGRLLQDNRALLGSAVSRPDARPDALAALFRHMHTVKGNARTYGLLRIADAA
HVAEQRYAALRDDPAGWGDAVLQSRLEAELEAVAGALQAYVRVNDGTLGRGAGHAVGDAQTVQLPRARIEELCARIGALA
RDPGCTPAHRAALERIAAALADADAAGLDEVVGGVAASLPALARDLGKEAPEVVLQSGVPVAVKPQAADALRNAFMHLLR
NALDHGIEPAAERAARGKPAAGRIRIGAALDAQELEIRLADDGRGLDLDRIQAQARARGLIAEDATPAPGDVAHLIFAPG
FSTAGEVTAVSGRGVGMDAVKAFVESLGGRIQLVLAGGAPRAATPFETVLRLPARWAVVA
>Mature_779_residues
TVRLRITLLIVLAFLALCSVGGFALYRSAEGARQVKRVTEGVVPSAIHSVELMGQLKDVQMAALGMVSASDADAAQKLHE
QLVERKAVLQKALDKQLQEADSDAQRGLVKEAAMSLENYFAAIDDTARFKLAGQQDAAEAFMAATVDQYLREQGQMIEAI
QVEKRRTKDEAIGSLNAQLEHTTTTLLAVAAVAILGLAAAGYLLYRQIVRPIREMELKMTEIATSQDFSHRVPVTRMDEI
GRSLTAFNAMVEKIQESSELVRRKTADIQAMLHTIPQGILTLQAGRTIHPEYSDHLARILEEDGIAGRTLDALLFDRSDL
SADARAQALAAIDACIGEDELNFSFNAHLLPQELQARFGGDRVKVIELGWSPITAADGTVERLLLSLRDVTELRELARDA
QARKEELAMVGELLGVAADRFREFSESAGRLLQDNRALLGSAVSRPDARPDALAALFRHMHTVKGNARTYGLLRIADAAH
VAEQRYAALRDDPAGWGDAVLQSRLEAELEAVAGALQAYVRVNDGTLGRGAGHAVGDAQTVQLPRARIEELCARIGALAR
DPGCTPAHRAALERIAAALADADAAGLDEVVGGVAASLPALARDLGKEAPEVVLQSGVPVAVKPQAADALRNAFMHLLRN
ALDHGIEPAAERAARGKPAAGRIRIGAALDAQELEIRLADDGRGLDLDRIQAQARARGLIAEDATPAPGDVAHLIFAPGF
STAGEVTAVSGRGVGMDAVKAFVESLGGRIQLVLAGGAPRAATPFETVLRLPARWAVVA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=161, Percent_Identity=40.9937888198758, Blast_Score=109, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83355; Mature: 83224

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50885 HAMP ; PS50894 HPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRLRITLLIVLAFLALCSVGGFALYRSAEGARQVKRVTEGVVPSAIHSVELMGQLKDV
CEEEEHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QMAALGMVSASDADAAQKLHEQLVERKAVLQKALDKQLQEADSDAQRGLVKEAAMSLENY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FAAIDDTARFKLAGQQDAAEAFMAATVDQYLREQGQMIEAIQVEKRRTKDEAIGSLNAQL
HHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EHTTTTLLAVAAVAILGLAAAGYLLYRQIVRPIREMELKMTEIATSQDFSHRVPVTRMDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IGRSLTAFNAMVEKIQESSELVRRKTADIQAMLHTIPQGILTLQAGRTIHPEYSDHLARI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHH
LEEDGIAGRTLDALLFDRSDLSADARAQALAAIDACIGEDELNFSFNAHLLPQELQARFG
HHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHC
GDRVKVIELGWSPITAADGTVERLLLSLRDVTELRELARDAQARKEELAMVGELLGVAAD
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFREFSESAGRLLQDNRALLGSAVSRPDARPDALAALFRHMHTVKGNARTYGLLRIADAA
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHEEHEEEHHHH
HVAEQRYAALRDDPAGWGDAVLQSRLEAELEAVAGALQAYVRVNDGTLGRGAGHAVGDAQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCH
TVQLPRARIEELCARIGALARDPGCTPAHRAALERIAAALADADAAGLDEVVGGVAASLP
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ALARDLGKEAPEVVLQSGVPVAVKPQAADALRNAFMHLLRNALDHGIEPAAERAARGKPA
HHHHHHCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
AGRIRIGAALDAQELEIRLADDGRGLDLDRIQAQARARGLIAEDATPAPGDVAHLIFAPG
CCEEEECCCCCHHHCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEECC
FSTAGEVTAVSGRGVGMDAVKAFVESLGGRIQLVLAGGAPRAATPFETVLRLPARWAVVA
CCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHCCCCCEECC
>Mature Secondary Structure 
TVRLRITLLIVLAFLALCSVGGFALYRSAEGARQVKRVTEGVVPSAIHSVELMGQLKDV
EEEEHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QMAALGMVSASDADAAQKLHEQLVERKAVLQKALDKQLQEADSDAQRGLVKEAAMSLENY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FAAIDDTARFKLAGQQDAAEAFMAATVDQYLREQGQMIEAIQVEKRRTKDEAIGSLNAQL
HHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EHTTTTLLAVAAVAILGLAAAGYLLYRQIVRPIREMELKMTEIATSQDFSHRVPVTRMDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IGRSLTAFNAMVEKIQESSELVRRKTADIQAMLHTIPQGILTLQAGRTIHPEYSDHLARI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHH
LEEDGIAGRTLDALLFDRSDLSADARAQALAAIDACIGEDELNFSFNAHLLPQELQARFG
HHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHC
GDRVKVIELGWSPITAADGTVERLLLSLRDVTELRELARDAQARKEELAMVGELLGVAAD
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFREFSESAGRLLQDNRALLGSAVSRPDARPDALAALFRHMHTVKGNARTYGLLRIADAA
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHEEHEEEHHHH
HVAEQRYAALRDDPAGWGDAVLQSRLEAELEAVAGALQAYVRVNDGTLGRGAGHAVGDAQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCH
TVQLPRARIEELCARIGALARDPGCTPAHRAALERIAAALADADAAGLDEVVGGVAASLP
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ALARDLGKEAPEVVLQSGVPVAVKPQAADALRNAFMHLLRNALDHGIEPAAERAARGKPA
HHHHHHCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
AGRIRIGAALDAQELEIRLADDGRGLDLDRIQAQARARGLIAEDATPAPGDVAHLIFAPG
CCEEEECCCCCHHHCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEECC
FSTAGEVTAVSGRGVGMDAVKAFVESLGGRIQLVLAGGAPRAATPFETVLRLPARWAVVA
CCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]