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The map label for this gene is aer [H]

Identifier: 120610790

GI number: 120610790

Start: 2322467

End: 2324119

Strand: Direct

Name: aer [H]

Synonym: Aave_2113

Alternate gene names: 120610790

Gene position: 2322467-2324119 (Clockwise)

Preceding gene: 120610786

Following gene: 120610791

Centisome position: 43.39

GC content: 70.66

Gene sequence:

>1653_bases
ATGCGCGTCAACCTTCCCGTCACCACCCAGGAATACCCCTTCCCACGGGGCGAGACACTGGTTTCCACCACCGACCTGCA
AGGGCGCATCCTCTACTGCAATCCCATGTTCGTGGAGGTGAGCGGGTACGAGCGCGCCGAGCTGCTGGGCCAGCCGCACA
ACATGATCCGCCACCCGGACATGCCGGAAGAGGCGTTCCGCGACATGTGGGAAACCATCGCCGCCGGGTGGCCGTGGTCC
GCCGCGGTGAAGAACCGCCGCAAGGACGGCACTTACTACTGGGTCATGGCCAACGTCACGCCGCTGATGGAGGACGGGCG
CCCGGTGGGATACATGTCCGTGCGCACCGAGGCCTCGCGCGAGCAGATCGCGGACGCGGAAGCGCTCTACGGCCGGATGC
GCGCGGAGAAGCAGGCCGGCCGCATGGTGCATGCGCTGCAGCGGGGCCGGGTCGTGCGCAGGACGCTGTCCGGACGCATC
CGCCAGGCGTTGGAGATCGGCCTGGGCGGGCAGGTGGCCATGGCCTTCGCTGCCGTATGGCTGGCGGCGTTCCTCGCGGG
ACTCGTGGACCAGGAATCGGGCATGTTCTCCGCGCTGGCGTGGCTGGCCGCCGCCGGCGTGGCCCTGGGCGGATTCGCAT
GGGTGCGCCGCACCGCCGTGCTGCCGCTCGTCGCCATGGTGGGGGCTGCCAACCGGATGGCGGCCGGCGACCTCACGCAG
AGCGTCACCGTGACGCGCACCGGCCTGACCGGCGAACTGCAGCGCGCGCTCGCGCAGCTCAACGTCAATCTGCTGTCCAT
CGTGCGCGACGCCCGGCAGGAGAGCGACAAGATGCGCATGTCGAGCCGCGAGATCGCGCAGGGCAACCAGGAGCTGTCTT
CCCGCACCGAGAACCAGGCGAGCAATCTGCAGCAGACGGCCGCCTCGATGGAGGAGATCACCGGCACCGTCAAGCAGACC
GCCGACTCCGCGCGCCAAGCCAGCGAACTCGCCCAGCAGGCCACCGGCGTGGCCGAGCGCACCAGCGGCGCGGTGGAAGA
GGTGGCCGCGACCATGCGCGAGATCCAGACCTCGTCCGGCCGCATCGGCGAAATCACCGGGCTGATCGATTCCATCGCCT
TCCAGACCAACATCCTCGCGCTGAACGCGGCCGTGGAGGCGGCGCGCGCGGGCGAGCACGGCCGCGGCTTCGCCGTGGTG
GCCGCCGAGGTGCGCAGCCTGTCGCAGCGCACACAGTCCGCCGCCAAGGAAATCCGCCAACTGATCGAGGAATCCGCGGC
GCGGGTGGGCGAGGGCCACGCGCGCACCGATGGTGCCCGCCGGACCATGCAGGAATCGCTCGAACTGGTGCGCCGCGTGG
GCGTGTTCATCGGGGAGATCCACAGCGCCTCGAACGAGCAGCTCTCGGGCATCTCGCAGGTGAATGCGGCCGTTGCCCAA
CTGGACACCATCACCCAGCAGAACGCGGCGCTGGTGGAGGAGAGCGCGGCTCTGGCCATCGAACTGGAACGGCAGGCGCA
GACCGTGTCGGAGTCGGTGCAGGTGTTCCGCCTGGACCGGGGGCCCCGCGCCGCCGCGCCCGACGCCGTGGCCCTGCGCA
AGGCGGCCAAGGCCGGCAGGGCCACCGCCGCGGCACTGCCCGCGCTGCGCTGA

Upstream 100 bases:

>100_bases
CATCAATTTTGCAGTTTTGACTTAATGCTTCATCAATAGCCGTCCGAGCCGAAACGCTGTCCCGCTTCCAACAGAAATCA
TCCAGCCGAGGAGAAACCCC

Downstream 100 bases:

>100_bases
CGCCCGCCGCGGCGGCTTTTTGCAACCTTGTGTATCCCGCCCGGCCATGGCCGGGCCACGCCCCGTTGCGGTCCGCGCGG
CTTGCATGGACACTGGCGCC

Product: Pas/Pac sensor containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MRVNLPVTTQEYPFPRGETLVSTTDLQGRILYCNPMFVEVSGYERAELLGQPHNMIRHPDMPEEAFRDMWETIAAGWPWS
AAVKNRRKDGTYYWVMANVTPLMEDGRPVGYMSVRTEASREQIADAEALYGRMRAEKQAGRMVHALQRGRVVRRTLSGRI
RQALEIGLGGQVAMAFAAVWLAAFLAGLVDQESGMFSALAWLAAAGVALGGFAWVRRTAVLPLVAMVGAANRMAAGDLTQ
SVTVTRTGLTGELQRALAQLNVNLLSIVRDARQESDKMRMSSREIAQGNQELSSRTENQASNLQQTAASMEEITGTVKQT
ADSARQASELAQQATGVAERTSGAVEEVAATMREIQTSSGRIGEITGLIDSIAFQTNILALNAAVEAARAGEHGRGFAVV
AAEVRSLSQRTQSAAKEIRQLIEESAARVGEGHARTDGARRTMQESLELVRRVGVFIGEIHSASNEQLSGISQVNAAVAQ
LDTITQQNAALVEESAALAIELERQAQTVSESVQVFRLDRGPRAAAPDAVALRKAAKAGRATAAALPALR

Sequences:

>Translated_550_residues
MRVNLPVTTQEYPFPRGETLVSTTDLQGRILYCNPMFVEVSGYERAELLGQPHNMIRHPDMPEEAFRDMWETIAAGWPWS
AAVKNRRKDGTYYWVMANVTPLMEDGRPVGYMSVRTEASREQIADAEALYGRMRAEKQAGRMVHALQRGRVVRRTLSGRI
RQALEIGLGGQVAMAFAAVWLAAFLAGLVDQESGMFSALAWLAAAGVALGGFAWVRRTAVLPLVAMVGAANRMAAGDLTQ
SVTVTRTGLTGELQRALAQLNVNLLSIVRDARQESDKMRMSSREIAQGNQELSSRTENQASNLQQTAASMEEITGTVKQT
ADSARQASELAQQATGVAERTSGAVEEVAATMREIQTSSGRIGEITGLIDSIAFQTNILALNAAVEAARAGEHGRGFAVV
AAEVRSLSQRTQSAAKEIRQLIEESAARVGEGHARTDGARRTMQESLELVRRVGVFIGEIHSASNEQLSGISQVNAAVAQ
LDTITQQNAALVEESAALAIELERQAQTVSESVQVFRLDRGPRAAAPDAVALRKAAKAGRATAAALPALR
>Mature_550_residues
MRVNLPVTTQEYPFPRGETLVSTTDLQGRILYCNPMFVEVSGYERAELLGQPHNMIRHPDMPEEAFRDMWETIAAGWPWS
AAVKNRRKDGTYYWVMANVTPLMEDGRPVGYMSVRTEASREQIADAEALYGRMRAEKQAGRMVHALQRGRVVRRTLSGRI
RQALEIGLGGQVAMAFAAVWLAAFLAGLVDQESGMFSALAWLAAAGVALGGFAWVRRTAVLPLVAMVGAANRMAAGDLTQ
SVTVTRTGLTGELQRALAQLNVNLLSIVRDARQESDKMRMSSREIAQGNQELSSRTENQASNLQQTAASMEEITGTVKQT
ADSARQASELAQQATGVAERTSGAVEEVAATMREIQTSSGRIGEITGLIDSIAFQTNILALNAAVEAARAGEHGRGFAVV
AAEVRSLSQRTQSAAKEIRQLIEESAARVGEGHARTDGARRTMQESLELVRRVGVFIGEIHSASNEQLSGISQVNAAVAQ
LDTITQQNAALVEESAALAIELERQAQTVSESVQVFRLDRGPRAAAPDAVALRKAAKAGRATAAALPALR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=514, Percent_Identity=41.0505836575875, Blast_Score=354, Evalue=1e-98,
Organism=Escherichia coli, GI1788195, Length=313, Percent_Identity=49.5207667731629, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1787690, Length=334, Percent_Identity=47.0059880239521, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1788194, Length=306, Percent_Identity=50, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI2367378, Length=309, Percent_Identity=50.1618122977346, Blast_Score=243, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 59305; Mature: 59305

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNLPVTTQEYPFPRGETLVSTTDLQGRILYCNPMFVEVSGYERAELLGQPHNMIRHPD
CEECCCCCCCCCCCCCCCEEEEECCCCCEEEEECCEEEEECCCHHHHHCCCCHHHCCCCC
MPEEAFRDMWETIAAGWPWSAAVKNRRKDGTYYWVMANVTPLMEDGRPVGYMSVRTEASR
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCEEEEECCHHHH
EQIADAEALYGRMRAEKQAGRMVHALQRGRVVRRTLSGRIRQALEIGLGGQVAMAFAAVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LAAFLAGLVDQESGMFSALAWLAAAGVALGGFAWVRRTAVLPLVAMVGAANRMAAGDLTQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
SVTVTRTGLTGELQRALAQLNVNLLSIVRDARQESDKMRMSSREIAQGNQELSSRTENQA
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SNLQQTAASMEEITGTVKQTADSARQASELAQQATGVAERTSGAVEEVAATMREIQTSSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHCCC
RIGEITGLIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAAEVRSLSQRTQSAAKEIRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIEESAARVGEGHARTDGARRTMQESLELVRRVGVFIGEIHSASNEQLSGISQVNAAVAQ
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LDTITQQNAALVEESAALAIELERQAQTVSESVQVFRLDRGPRAAAPDAVALRKAAKAGR
HHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCC
ATAAALPALR
HHHHHCCCCC
>Mature Secondary Structure
MRVNLPVTTQEYPFPRGETLVSTTDLQGRILYCNPMFVEVSGYERAELLGQPHNMIRHPD
CEECCCCCCCCCCCCCCCEEEEECCCCCEEEEECCEEEEECCCHHHHHCCCCHHHCCCCC
MPEEAFRDMWETIAAGWPWSAAVKNRRKDGTYYWVMANVTPLMEDGRPVGYMSVRTEASR
CCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCEEEEECCHHHH
EQIADAEALYGRMRAEKQAGRMVHALQRGRVVRRTLSGRIRQALEIGLGGQVAMAFAAVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LAAFLAGLVDQESGMFSALAWLAAAGVALGGFAWVRRTAVLPLVAMVGAANRMAAGDLTQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
SVTVTRTGLTGELQRALAQLNVNLLSIVRDARQESDKMRMSSREIAQGNQELSSRTENQA
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SNLQQTAASMEEITGTVKQTADSARQASELAQQATGVAERTSGAVEEVAATMREIQTSSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHCCC
RIGEITGLIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAAEVRSLSQRTQSAAKEIRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIEESAARVGEGHARTDGARRTMQESLELVRRVGVFIGEIHSASNEQLSGISQVNAAVAQ
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LDTITQQNAALVEESAALAIELERQAQTVSESVQVFRLDRGPRAAAPDAVALRKAAKAGR
HHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCC
ATAAALPALR
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]