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The map label for this gene is serB [H]

Identifier: 120610261

GI number: 120610261

Start: 1739058

End: 1739771

Strand: Reverse

Name: serB [H]

Synonym: Aave_1576

Alternate gene names: 120610261

Gene position: 1739771-1739058 (Counterclockwise)

Preceding gene: 120610264

Following gene: 120610260

Centisome position: 32.5

GC content: 70.45

Gene sequence:

>714_bases
ATGACCCATGCCACCGAATTCGCCCCCGGCCTCGTCCTGCGGGGCATCGAGCCTCCGCTGTCCCTGTCGGACTACAAGCT
GATCGCCTTCGACATGGACTCCACGCTGATCAACATCGAGTGCGTGGACGAGATCGCGGACGCCGCCGGGCGCAAGGCCG
AGGTGGCCGCCATCACCGAGGCCGCCATGCAGGGCCTGATCACCGACTACAAGGAGAGCCTGCGCCAGCGGGTGGCGCTG
CTGCGCGGCGTGGGCGTGGAGCACATGGAGCAGGTCTTCCGCGAGCGCCTGCGCTTCAACCCCGGTGCGAAGGAACTCAT
CGACGCCGCCAAGGCCGCGGGCCTCGCCACGCTGCTGGTGTCGGGCGGGTTCACGTTCTTCTCGGACCGGGTGCGCGCCG
GCCTGGGGATCGACCTCTCGCGCGCCAACGTGCTGGAGATCGAGGACGGCCGCCTCACGGGCCGCATGGTGGACCAGCCC
TGGGGCGACATCTGCGACGGCGCCGAGAAGCGCCGCACGCTGCTGGAAGTGGCCTCGCTGATGGGCATCGACCCGTCGCA
GGCGATCGCGGTGGGCGACGGCGCCAACGACCTGCCCATGATGGGCGTGGCCGGCCTGTCCGTGGCCTTCCACGCGAAAC
CCGCCGTGCGCGCGCAGGCCAAGGTGGCGATCAACGAGGGCGGCCTCGACCGGCTGCTGGACATCCTGCGGTGA

Upstream 100 bases:

>100_bases
TTCGGGGGCGGATGGTACGGGAGCGGCACCGCGCCGCACAAGCCCGGGCCGGCACGGAGATAACATCGCCGACTTTCCGC
CAACCGCTGTTCCAAGCACC

Downstream 100 bases:

>100_bases
GGCCTCGGGAAGGCATAAGTAGCAGCCGCGTTATATGGGTATGACAATAAAAACGTGGTGAGCCTGCGGGAAACTACCTA
GACTCCGGGCCCATGGGCGA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTHATEFAPGLVLRGIEPPLSLSDYKLIAFDMDSTLINIECVDEIADAAGRKAEVAAITEAAMQGLITDYKESLRQRVAL
LRGVGVEHMEQVFRERLRFNPGAKELIDAAKAAGLATLLVSGGFTFFSDRVRAGLGIDLSRANVLEIEDGRLTGRMVDQP
WGDICDGAEKRRTLLEVASLMGIDPSQAIAVGDGANDLPMMGVAGLSVAFHAKPAVRAQAKVAINEGGLDRLLDILR

Sequences:

>Translated_237_residues
MTHATEFAPGLVLRGIEPPLSLSDYKLIAFDMDSTLINIECVDEIADAAGRKAEVAAITEAAMQGLITDYKESLRQRVAL
LRGVGVEHMEQVFRERLRFNPGAKELIDAAKAAGLATLLVSGGFTFFSDRVRAGLGIDLSRANVLEIEDGRLTGRMVDQP
WGDICDGAEKRRTLLEVASLMGIDPSQAIAVGDGANDLPMMGVAGLSVAFHAKPAVRAQAKVAINEGGLDRLLDILR
>Mature_236_residues
THATEFAPGLVLRGIEPPLSLSDYKLIAFDMDSTLINIECVDEIADAAGRKAEVAAITEAAMQGLITDYKESLRQRVALL
RGVGVEHMEQVFRERLRFNPGAKELIDAAKAAGLATLLVSGGFTFFSDRVRAGLGIDLSRANVLEIEDGRLTGRMVDQPW
GDICDGAEKRRTLLEVASLMGIDPSQAIAVGDGANDLPMMGVAGLSVAFHAKPAVRAQAKVAINEGGLDRLLDILR

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Escherichia coli, GI1790849, Length=210, Percent_Identity=44.7619047619048, Blast_Score=160, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6321647, Length=212, Percent_Identity=39.1509433962264, Blast_Score=142, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24661601, Length=229, Percent_Identity=27.5109170305677, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 25385; Mature: 25253

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHATEFAPGLVLRGIEPPLSLSDYKLIAFDMDSTLINIECVDEIADAAGRKAEVAAITE
CCCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCEEEEHEEHHHHHHHCCCCHHHHHHHH
AAMQGLITDYKESLRQRVALLRGVGVEHMEQVFRERLRFNPGAKELIDAAKAAGLATLLV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SGGFTFFSDRVRAGLGIDLSRANVLEIEDGRLTGRMVDQPWGDICDGAEKRRTLLEVASL
HCCCHHHHHHHHHCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHH
MGIDPSQAIAVGDGANDLPMMGVAGLSVAFHAKPAVRAQAKVAINEGGLDRLLDILR
HCCCCCCEEEECCCCCCCCCHHHHHCEEEEECCCCHHHHEEEEECCCCHHHHHHHHC
>Mature Secondary Structure 
THATEFAPGLVLRGIEPPLSLSDYKLIAFDMDSTLINIECVDEIADAAGRKAEVAAITE
CCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCEEEEHEEHHHHHHHCCCCHHHHHHHH
AAMQGLITDYKESLRQRVALLRGVGVEHMEQVFRERLRFNPGAKELIDAAKAAGLATLLV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SGGFTFFSDRVRAGLGIDLSRANVLEIEDGRLTGRMVDQPWGDICDGAEKRRTLLEVASL
HCCCHHHHHHHHHCCCCEECCCEEEEECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHH
MGIDPSQAIAVGDGANDLPMMGVAGLSVAFHAKPAVRAQAKVAINEGGLDRLLDILR
HCCCCCCEEEECCCCCCCCCHHHHHCEEEEECCCCHHHHEEEEECCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]