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The map label for this gene is btr [H]

Identifier: 120610215

GI number: 120610215

Start: 1694579

End: 1695298

Strand: Reverse

Name: btr [H]

Synonym: Aave_1530

Alternate gene names: 120610215

Gene position: 1695298-1694579 (Counterclockwise)

Preceding gene: 120610220

Following gene: 120610204

Centisome position: 31.67

GC content: 65.97

Gene sequence:

>720_bases
ATGAATCCGCACACCATCAAGGTCGCCTGCTCGAACTGCAACCTGCGCGAGCTCTGCATGCCGCTGGGCCTGAACGAGCA
GCAGCTGCAGCGCATCGATGACATCGTCGCCACGCGCCGCAAGGTCAAGCGCGGCGGCACGCTGTTCCGCAACGGCGAGG
CCTTCACGTCGCTCTTCGCCATCCGCACGGGCTTCTTCAAGACCTGCGTGGCCACCGAGGACGGACGCGACCAGGTGACG
GGCTTCCAGATGGCCGGCGAGATCATCGGGCTCGACGGCATCGTCAGCGACCACCACACCTGCGACGCCGTCGCGCTGGA
GGATGCCGAGGTGTGCGTCATGCCCTTCGAGCGCATCGAGGAGCTGTCGCGCGAGGTCACCGCCCTGCAGCACCACGTCC
ACAAGATCATGAGCCGCGAGATCGTGCGCGAGCACGGCGTGATGCTGCTGCTCGGCAGCATGCGCGCGGAGGAGCGCCTC
GCCGCCTTCCTGCTCAACCTCGTTCAGCGCCTGCATGCGCGGGGCTTCTCGCAGTCCGAACTGGTGCTGCGCATGACCCG
CGAGGAGATCGGCAGCTACCTGGGCCTCAAGCTGGAGACCGTGAGCCGCACCTTCTCCAAGTTCGTCGAGGAAGGCATCG
TCGAGGTCAAGCAGCGGCACGTGCGCATCGTCGAGCCGGATGCGCTCAAGCGGATCGTGAACAGCCAGGCTTGTAGTTGA

Upstream 100 bases:

>100_bases
CCACATTCTTTTTTGCACGCCTGCGCTCCCGCCATGCGTCGAACCGTGGCCGGCCTGCATGCACAGCGAGATAGAACACA
GAAGGTAAGGCTGCTCATCC

Downstream 100 bases:

>100_bases
CATCCCCCTGAGGCGCTGCGCGCCTTCTGACGGGTGAGGCCGTGCGTGTCCATGGGCCTTGCGCTGCGCCAATGCTCTGC
GGGAAATGCGGGGTCCTTGC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNPHTIKVACSNCNLRELCMPLGLNEQQLQRIDDIVATRRKVKRGGTLFRNGEAFTSLFAIRTGFFKTCVATEDGRDQVT
GFQMAGEIIGLDGIVSDHHTCDAVALEDAEVCVMPFERIEELSREVTALQHHVHKIMSREIVREHGVMLLLGSMRAEERL
AAFLLNLVQRLHARGFSQSELVLRMTREEIGSYLGLKLETVSRTFSKFVEEGIVEVKQRHVRIVEPDALKRIVNSQACS

Sequences:

>Translated_239_residues
MNPHTIKVACSNCNLRELCMPLGLNEQQLQRIDDIVATRRKVKRGGTLFRNGEAFTSLFAIRTGFFKTCVATEDGRDQVT
GFQMAGEIIGLDGIVSDHHTCDAVALEDAEVCVMPFERIEELSREVTALQHHVHKIMSREIVREHGVMLLLGSMRAEERL
AAFLLNLVQRLHARGFSQSELVLRMTREEIGSYLGLKLETVSRTFSKFVEEGIVEVKQRHVRIVEPDALKRIVNSQACS
>Mature_239_residues
MNPHTIKVACSNCNLRELCMPLGLNEQQLQRIDDIVATRRKVKRGGTLFRNGEAFTSLFAIRTGFFKTCVATEDGRDQVT
GFQMAGEIIGLDGIVSDHHTCDAVALEDAEVCVMPFERIEELSREVTALQHHVHKIMSREIVREHGVMLLLGSMRAEERL
AAFLLNLVQRLHARGFSQSELVLRMTREEIGSYLGLKLETVSRTFSKFVEEGIVEVKQRHVRIVEPDALKRIVNSQACS

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=226, Percent_Identity=42.0353982300885, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26961; Mature: 26961

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPHTIKVACSNCNLRELCMPLGLNEQQLQRIDDIVATRRKVKRGGTLFRNGEAFTSLFA
CCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH
IRTGFFKTCVATEDGRDQVTGFQMAGEIIGLDGIVSDHHTCDAVALEDAEVCVMPFERIE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEECCHHHHH
ELSREVTALQHHVHKIMSREIVREHGVMLLLGSMRAEERLAAFLLNLVQRLHARGFSQSE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LVLRMTREEIGSYLGLKLETVSRTFSKFVEEGIVEVKQRHVRIVEPDALKRIVNSQACS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHCCCC
>Mature Secondary Structure
MNPHTIKVACSNCNLRELCMPLGLNEQQLQRIDDIVATRRKVKRGGTLFRNGEAFTSLFA
CCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHH
IRTGFFKTCVATEDGRDQVTGFQMAGEIIGLDGIVSDHHTCDAVALEDAEVCVMPFERIE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEECCHHHHH
ELSREVTALQHHVHKIMSREIVREHGVMLLLGSMRAEERLAAFLLNLVQRLHARGFSQSE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LVLRMTREEIGSYLGLKLETVSRTFSKFVEEGIVEVKQRHVRIVEPDALKRIVNSQACS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]