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The map label for this gene is crtB [H]

Identifier: 120610143

GI number: 120610143

Start: 1603235

End: 1604095

Strand: Reverse

Name: crtB [H]

Synonym: Aave_1456

Alternate gene names: 120610143

Gene position: 1604095-1603235 (Counterclockwise)

Preceding gene: 120610144

Following gene: 120610142

Centisome position: 29.97

GC content: 64.81

Gene sequence:

>861_bases
ATGGGACAATCCTCCTTCATGACACCGGAACAGTACGTCCAACAAAAAGCCGCGGCGTCCGGCAGCAGCTTCTATTACGC
ATTCCTGTTCCTCCCGCCCGCCAGACGGGCCGCCATCACCGCCTTCTATGCATTCTGCCGCGAGGTGGACGACGTGGTGG
ACGAGGTGTCGGACGCCGGCGTGGCCCGGACCAAGCTGGCCTGGTGGCAGGCGGAAGTCGCCCGCTCGTTCGCGGGCCAG
CCCCCGGCGCATCCCGTGATGCAGGCCTTGATGCCGCACACCGGCATGTACGGCATCGAGGAGCGCCACCTGCAGGCCGT
GATAGAGGGGTGCCAGATGGACCTCGAACAGACCCGCTACCTGGACTTCCAGGGCCTTTCTCGGTATTGCCACCTGGTGG
CGGGCATCGTCGGCGAGGTGGCGGCGCGCATCTTCGGCCCCTCCGACGAACGCACCGTGGAATACGCCCATACCCTGGGC
CTCGCTTTCCAGCTGACGAACATCATCCGGGACGTCGGCGAGGACGCGATGATGGGCCGCATCTACCTTCCCGTGGCGGA
GCTGCAGCAGTTCGACGTCAAGGCCCATGAAATCCTGAAGCGGCAGTATTCCGACCGTTTCACGGCGCTGATGCGCTTCC
AGGCAGAACGCGCCCATGGTCTTTATGACAAGGCCCTCTCCCTGCTCCCGGGCGACCAGCGGCGGGCACAGAAACCCGGA
TTGATGATGGCCAGCATTTACCGGACCCTGCTGCGGGAAATCGAGAGGGACCAGTTCCAGGTGCTGCACCAGCGGATCGC
ACTCACGCCCCTGCGCAAGCTGTGGCTGGCGTGGAAGATGCAGGCCCTGGGCCGGATGTGA

Upstream 100 bases:

>100_bases
GCCTTTTTTGTTTTTCACCTGGCCGGTATGCCCCCTCTTCCGGCATCCGCGGTCCCGAGCCCCTTTTGGCGCACGGCCGG
GCTCGGGATGCCGTTTCTGC

Downstream 100 bases:

>100_bases
TGGCGCTGCGCCGCTTCTTCCGGCCGCGTCCAGCCCTGGCCGCCTGTCGCGCCCGCAGGGCAGCCCCCTGCCCCCGCACT
GTGGGCTGACGCCATGCAGG

Product: farnesyl-diphosphate farnesyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MGQSSFMTPEQYVQQKAAASGSSFYYAFLFLPPARRAAITAFYAFCREVDDVVDEVSDAGVARTKLAWWQAEVARSFAGQ
PPAHPVMQALMPHTGMYGIEERHLQAVIEGCQMDLEQTRYLDFQGLSRYCHLVAGIVGEVAARIFGPSDERTVEYAHTLG
LAFQLTNIIRDVGEDAMMGRIYLPVAELQQFDVKAHEILKRQYSDRFTALMRFQAERAHGLYDKALSLLPGDQRRAQKPG
LMMASIYRTLLREIERDQFQVLHQRIALTPLRKLWLAWKMQALGRM

Sequences:

>Translated_286_residues
MGQSSFMTPEQYVQQKAAASGSSFYYAFLFLPPARRAAITAFYAFCREVDDVVDEVSDAGVARTKLAWWQAEVARSFAGQ
PPAHPVMQALMPHTGMYGIEERHLQAVIEGCQMDLEQTRYLDFQGLSRYCHLVAGIVGEVAARIFGPSDERTVEYAHTLG
LAFQLTNIIRDVGEDAMMGRIYLPVAELQQFDVKAHEILKRQYSDRFTALMRFQAERAHGLYDKALSLLPGDQRRAQKPG
LMMASIYRTLLREIERDQFQVLHQRIALTPLRKLWLAWKMQALGRM
>Mature_285_residues
GQSSFMTPEQYVQQKAAASGSSFYYAFLFLPPARRAAITAFYAFCREVDDVVDEVSDAGVARTKLAWWQAEVARSFAGQP
PAHPVMQALMPHTGMYGIEERHLQAVIEGCQMDLEQTRYLDFQGLSRYCHLVAGIVGEVAARIFGPSDERTVEYAHTLGL
AFQLTNIIRDVGEDAMMGRIYLPVAELQQFDVKAHEILKRQYSDRFTALMRFQAERAHGLYDKALSLLPGDQRRAQKPGL
MMASIYRTLLREIERDQFQVLHQRIALTPLRKLWLAWKMQALGRM

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene [H]

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

Organism=Homo sapiens, GI124517691, Length=259, Percent_Identity=21.2355212355212, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR019845
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: =2.5.1.32 [H]

Molecular weight: Translated: 32569; Mature: 32438

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS01045 SQUALEN_PHYTOEN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQSSFMTPEQYVQQKAAASGSSFYYAFLFLPPARRAAITAFYAFCREVDDVVDEVSDAG
CCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VARTKLAWWQAEVARSFAGQPPAHPVMQALMPHTGMYGIEERHLQAVIEGCQMDLEQTRY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDFQGLSRYCHLVAGIVGEVAARIFGPSDERTVEYAHTLGLAFQLTNIIRDVGEDAMMGR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IYLPVAELQQFDVKAHEILKRQYSDRFTALMRFQAERAHGLYDKALSLLPGDQRRAQKPG
HCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCC
LMMASIYRTLLREIERDQFQVLHQRIALTPLRKLWLAWKMQALGRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GQSSFMTPEQYVQQKAAASGSSFYYAFLFLPPARRAAITAFYAFCREVDDVVDEVSDAG
CCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
VARTKLAWWQAEVARSFAGQPPAHPVMQALMPHTGMYGIEERHLQAVIEGCQMDLEQTRY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDFQGLSRYCHLVAGIVGEVAARIFGPSDERTVEYAHTLGLAFQLTNIIRDVGEDAMMGR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IYLPVAELQQFDVKAHEILKRQYSDRFTALMRFQAERAHGLYDKALSLLPGDQRRAQKPG
HCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCC
LMMASIYRTLLREIERDQFQVLHQRIALTPLRKLWLAWKMQALGRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA