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The map label for this gene is qor [H]

Identifier: 120610100

GI number: 120610100

Start: 1553646

End: 1554620

Strand: Reverse

Name: qor [H]

Synonym: Aave_1413

Alternate gene names: 120610100

Gene position: 1554620-1553646 (Counterclockwise)

Preceding gene: 120610134

Following gene: 120610099

Centisome position: 29.04

GC content: 69.95

Gene sequence:

>975_bases
ATGCATGCATGGCTTTGCACCCAGCCCACGGGCGTGGACAACCTCGCCTGGACCGAGTTGCCGACGCCGGTCCCCAAGCG
CGGCGAGGTGCTGATCGAGATCCGCGCCGCGAGCCTGAACTTTCCCGATCTGCTGATCGTGCAGAACAAGTACCAGATGA
AGCCCGATCCGCCGTTCGTGCCGGGCTCGGAGTACGCCGGGGTGGTCCAGGCCGTGGGCGAAGGCGTGGAGCACCTGCGC
GTGGGCCAGAACGTGGCCTGCCTGACGGGAACCGGCGGCTTCGCGACCCATGCCATCGCGCCCGCGGCGCTGTGCATGCC
GCTGCCGGACGGTTTCCCGCACGTGGACGCCGCGGCCTTCATCATGATCTACGCCACGTCGCACCATGCGCTGGTGGACC
GGGCGCAGCTGCGGGCCGGCGAGACGGTGCTGGTGCTGGGCGCGGCCGGCGGCGTGGGCACCGCGGCGATCCAGATCGCC
AAGAAGATGGGCGCGCGCGTGATCGCGGCGGCCTCTTCGGACGAGAAATGCGCGCTGTGCCTTTCCACCGGCGCCGACGC
GGTGATCAACTACAGCGCCGAAAACCTGCGCGAGGCGATCAAGGGCCTCACGGACGGCAAGGGCCCGGACGTGATCTACG
ACCCCGTGGGCGGCGACTTCACCGAGCCGGCCTTCCGCTCCATCGCCTGGCGCGGCCGCTACCTCGTGGTGGGCTTCGCG
GCCGGCCCGATCCCCTCGCTGCCCCTGAACCTGGCGCTGCTCAAGGGCGCATCGATCGTGGGCGTGTTCTGGGGCGAGTT
CTCCCGGCGCGAGCCCAAGGCGAATGCGGCCATGATGGCGGAGCTGGCCCGCTGGTACGGCGAAGGCTCGGTCAAGCCGG
TGATCGACCGCACCATGCCCATGGCCCAGCTGCATGCGGCCTACGAACGGATGGCGTCGCGGGCCGTGCAGGGCAAGCTG
GTGCTGGTGAACTGA

Upstream 100 bases:

>100_bases
TCCCACGGGCGGCCGCCGGTGGGGGGCCGTCGCTCCAGGGACATCGGCCCCGCGCGCAGGGCGCCTATGATGCCCGCGCA
ACCACAGAAGGAGACCCCGC

Downstream 100 bases:

>100_bases
CCTCCCGGCGGCGGGCCCGGCCACGGACGCCGCGTGCCGCCCTGCGGAACTGCCGCGCCGGCCCCGCGGGGCCGCTCCGG
CCGCGCTGTTCAAGGTGTCC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MHAWLCTQPTGVDNLAWTELPTPVPKRGEVLIEIRAASLNFPDLLIVQNKYQMKPDPPFVPGSEYAGVVQAVGEGVEHLR
VGQNVACLTGTGGFATHAIAPAALCMPLPDGFPHVDAAAFIMIYATSHHALVDRAQLRAGETVLVLGAAGGVGTAAIQIA
KKMGARVIAAASSDEKCALCLSTGADAVINYSAENLREAIKGLTDGKGPDVIYDPVGGDFTEPAFRSIAWRGRYLVVGFA
AGPIPSLPLNLALLKGASIVGVFWGEFSRREPKANAAMMAELARWYGEGSVKPVIDRTMPMAQLHAAYERMASRAVQGKL
VLVN

Sequences:

>Translated_324_residues
MHAWLCTQPTGVDNLAWTELPTPVPKRGEVLIEIRAASLNFPDLLIVQNKYQMKPDPPFVPGSEYAGVVQAVGEGVEHLR
VGQNVACLTGTGGFATHAIAPAALCMPLPDGFPHVDAAAFIMIYATSHHALVDRAQLRAGETVLVLGAAGGVGTAAIQIA
KKMGARVIAAASSDEKCALCLSTGADAVINYSAENLREAIKGLTDGKGPDVIYDPVGGDFTEPAFRSIAWRGRYLVVGFA
AGPIPSLPLNLALLKGASIVGVFWGEFSRREPKANAAMMAELARWYGEGSVKPVIDRTMPMAQLHAAYERMASRAVQGKL
VLVN
>Mature_324_residues
MHAWLCTQPTGVDNLAWTELPTPVPKRGEVLIEIRAASLNFPDLLIVQNKYQMKPDPPFVPGSEYAGVVQAVGEGVEHLR
VGQNVACLTGTGGFATHAIAPAALCMPLPDGFPHVDAAAFIMIYATSHHALVDRAQLRAGETVLVLGAAGGVGTAAIQIA
KKMGARVIAAASSDEKCALCLSTGADAVINYSAENLREAIKGLTDGKGPDVIYDPVGGDFTEPAFRSIAWRGRYLVVGFA
AGPIPSLPLNLALLKGASIVGVFWGEFSRREPKANAAMMAELARWYGEGSVKPVIDRTMPMAQLHAAYERMASRAVQGKL
VLVN

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=321, Percent_Identity=31.7757009345794, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI22538444, Length=321, Percent_Identity=31.7757009345794, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI194239674, Length=308, Percent_Identity=31.8181818181818, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI13236495, Length=308, Percent_Identity=31.8181818181818, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=30, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI28557745, Length=272, Percent_Identity=32.7205882352941, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI194239676, Length=308, Percent_Identity=29.8701298701299, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI24308257, Length=334, Percent_Identity=26.0479041916168, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI41872631, Length=300, Percent_Identity=27.3333333333333, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI47519420, Length=334, Percent_Identity=27.8443113772455, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI197927207, Length=194, Percent_Identity=31.4432989690722, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI226056130, Length=242, Percent_Identity=33.4710743801653, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226059159, Length=242, Percent_Identity=33.4710743801653, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226059133, Length=242, Percent_Identity=33.4710743801653, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI67078404, Length=305, Percent_Identity=26.5573770491803, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI67078406, Length=298, Percent_Identity=26.8456375838926, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=30.9597523219814, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787863, Length=323, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=311, Percent_Identity=27.9742765273312, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71987554, Length=371, Percent_Identity=25.0673854447439, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536829, Length=282, Percent_Identity=29.0780141843972, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=28.3950617283951, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324486, Length=338, Percent_Identity=27.810650887574, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=338, Percent_Identity=27.5147928994083, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323729, Length=338, Percent_Identity=24.8520710059172, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=24.5562130177515, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581345, Length=323, Percent_Identity=24.7678018575851, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920632, Length=296, Percent_Identity=23.9864864864865, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330659, Length=296, Percent_Identity=23.9864864864865, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550423, Length=158, Percent_Identity=33.5443037974684, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34253; Mature: 34253

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAWLCTQPTGVDNLAWTELPTPVPKRGEVLIEIRAASLNFPDLLIVQNKYQMKPDPPFV
CCCEEECCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSEYAGVVQAVGEGVEHLRVGQNVACLTGTGGFATHAIAPAALCMPLPDGFPHVDAAAF
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHEECCCCCCCCCCCEEE
IMIYATSHHALVDRAQLRAGETVLVLGAAGGVGTAAIQIAKKMGARVIAAASSDEKCALC
EEEEECCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEE
LSTGADAVINYSAENLREAIKGLTDGKGPDVIYDPVGGDFTEPAFRSIAWRGRYLVVGFA
EECCCCEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHCCCCEEEEEEE
AGPIPSLPLNLALLKGASIVGVFWGEFSRREPKANAAMMAELARWYGEGSVKPVIDRTMP
CCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCC
MAQLHAAYERMASRAVQGKLVLVN
HHHHHHHHHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MHAWLCTQPTGVDNLAWTELPTPVPKRGEVLIEIRAASLNFPDLLIVQNKYQMKPDPPFV
CCCEEECCCCCCCCCEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSEYAGVVQAVGEGVEHLRVGQNVACLTGTGGFATHAIAPAALCMPLPDGFPHVDAAAF
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHEECCCCCCCCCCCEEE
IMIYATSHHALVDRAQLRAGETVLVLGAAGGVGTAAIQIAKKMGARVIAAASSDEKCALC
EEEEECCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEE
LSTGADAVINYSAENLREAIKGLTDGKGPDVIYDPVGGDFTEPAFRSIAWRGRYLVVGFA
EECCCCEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHCCCCEEEEEEE
AGPIPSLPLNLALLKGASIVGVFWGEFSRREPKANAAMMAELARWYGEGSVKPVIDRTMP
CCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCC
MAQLHAAYERMASRAVQGKLVLVN
HHHHHHHHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]