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The map label for this gene is ppsA [H]

Identifier: 120610069

GI number: 120610069

Start: 1514840

End: 1517230

Strand: Direct

Name: ppsA [H]

Synonym: Aave_1382

Alternate gene names: 120610069

Gene position: 1514840-1517230 (Clockwise)

Preceding gene: 120610067

Following gene: 120610070

Centisome position: 28.3

GC content: 67.42

Gene sequence:

>2391_bases
ATGTCTGCACTGTTCGAACCGACCGCCCTGGTCGTTCCGTTTGAGAACCTGAGAATGACCGACGTCGAGTCGGTGGGTGG
CAAGAACGCCTCCCTCGGCGAGATGATCTCCCAGCTGCCCGACGGCGTGCGCGTGCCCACCGGCTTCGCGACCACCGCCC
ACGCCTTCCGCCAGTTCCTCGCCCACGACGGCCTGGCGCAGAAGATCAGCGACCGCCTCAAGACCCTCGACACCGAGGAC
GTGCGCGCCCTGGCCGCGGCCGGCGCCGAGATCCGCGCCATGGTCGAGGCCCAGCCCTTCCCGGCCGACCTCGAGAAGGC
CATCCGCGATGCCTTCGCCACGCTGTGCGGCGGCAATGCCGAGGCCTGCTTCGCCGTGCGTTCCTCCGCCACCGCGGAAG
ACCTGCCCGACGCCTCATTCGCCGGCCAGCAGGAAACCTTCCTGAACGTGGTGGGCATCGAGGATGTGCTGCACAAGATG
AAGGAGGTGTTCGCCTCCCTCTACAACGACCGCGCCATCAGCTACCGCGTGCACAAGGGCTTCGCGCACGACGTGGTGGC
CCTTTCTGCGGGCGTGCAGCGCATGGTGCGCTCCGACAAGGGCGCCGCGGGCGTGATGTTCACGATCGACACCGAATCCG
GCTTCGACCAGGTGGTGTTCATCACCTCCAGCTACGGCCTGGGCGAGACGGTGGTGCAGGGCGCCGTGAACCCCGACGAG
TTCTACGTGCACAAGCCCATGCTGGCCGCCGGCAACCGGGCCGTGATCCGCCGCAACCTCGGCAGCAAGCTCATCCAGAT
GGTGTTCGCCTCGCCCGAGGAGAAGAAGGCCAGCGGCAAGCTCGTGAAGACCACCGACGTGCCCACCGAGCAGCGCAACC
GCTACTCCCTGACGGACGCCGAGGTGGAACAGCTGGCGCGCTACGCCCTGCTCATCGAGAAGCACTACGGCCGCCCGATG
GACATCGAGTGGGGCAAGGACGGCACCGACGGCCAGCTCTACATCCTGCAGGCCCGCCCCGAGACGGTGAAGAGCCAGCA
GCAGGGCCAGGCCGAGCAGAAGTTCAAGCTCAAGGGCACGGGCACGGTGCTGGCCGAGGGCCGCGCCATCGGCCAGAAGA
TCGGCACGGGCCCGGTCCGCCTCGTGAGCGACATCGCCGAGATGGACAAGGTGCAGCCCGGCGACGTGCTGGTCACCGAC
ATGACCGACCCCAACTGGGAGCCCGTGATGAAGCGCGCCAGCGCCATTGTCACCAACCGCGGCGGCCGCACCTGCCACGC
GGCCATCATCGCGCGCGAACTCGGCATTCCGGCCGTGGTCGGCTGCGGCGACGCCACCAGCCTGCTCAAGGACGGCACGC
TGGTGACGGTGAGCTGCGCCGAGGGCGATACCGGCCGCATCTACGACGGCCTGCTGGAAACCGAGGTGACCGAGGTGCAG
CGCGGCGAGATGCCCAAGATCTCCACCAAGATCATGATGAACGTGGGCAATCCCCAGCTGGCCTTCGACTTCTGCCAGTT
GCCCAACGAGGGCGTGGGCCTGGCGCGGCTGGAGTTCATCATCAACAACAACATCGGCGTGCACCCCAAGGCCATCCTGG
ACTACCCCGCCGTCGATGCCGACCTGAAGAAGGCCGTGGAATCGGTGGCGCGCGGCCATGCCAGCCCCCGTGCCTTCTAC
GTGGACAAGGTGGCCGAGGGCGTGGCGACCATCGCCGCGGCCTTCTGGCCCAAGCCCGTCATCGTGCGCCTGTCGGACTT
CAAGTCCAATGAATACCGCAAGCTCATCGGCGGCAGCCGCTACGAGCCCGAGGAAGAGAACCCGATGCTGGGCTTCCGCG
GCGCGGCGCGCTACATCAGCCAGGACTTCGGCGAGGCCTTCGCGATGGAATGCGAAGCCCTGAAGCGCGTGCGCAACGAC
ATGGGCCTGACCAACGTGCAGGTGATGGTGCCCTTCGTGCGCACGCTGGGCCAGGCCGACCGCGTGACGAAGCTGCTGGC
CGAGCACGGCCTCAAGCGCGGCGAGAACGAACTCAAGCTCATCATGATGTGCGAGGTGCCGTCGAATGCCGTGCTGGCCG
ACGAGTTCCTGCAATTCTTCGACGGTTTCTCGGTGGGCTCCAACGACCTGACCCAGCTCACCCTGGGCCTGGACCGCGAC
TCCGGCCTGGAACTGCTGGCCGCCGACTTCGACGAGCGCGACCCGGCCGTGCAGGCGCTGCTCTCGCGCGCCATCGAGGC
CTGCAAACGCCAGGGCAAATACGTGGGCATCTGCGGCCAGGGCCCCAGCGACCACCCGGACTTCGCGCTGTGGCTGGCGG
AGCAGGGCATCTCGTCGATCTCGCTCAACCCCGACAGCGTGATCGCCACCTGGCAGAAACTCGCTGGCTGA

Upstream 100 bases:

>100_bases
CGCCGTGCATGCGTGATGATGGCGCCCCCGCCGGCCCGCCCTCGCGCGCGGGCGGCCCCCTGGGGCGCGCAGACCCGGTT
TCAACTTCTGGAGCTTCCCC

Downstream 100 bases:

>100_bases
CGGCCCGCGCCGGACCATGCCCGCGCCGCCGCCACCCCCTGCGCCGCGGGCCGCGGACGGCCGCGAGCGCGCGGCCCCCG
ACCCCTACGGCGAAGGCGGA

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MSALFEPTALVVPFENLRMTDVESVGGKNASLGEMISQLPDGVRVPTGFATTAHAFRQFLAHDGLAQKISDRLKTLDTED
VRALAAAGAEIRAMVEAQPFPADLEKAIRDAFATLCGGNAEACFAVRSSATAEDLPDASFAGQQETFLNVVGIEDVLHKM
KEVFASLYNDRAISYRVHKGFAHDVVALSAGVQRMVRSDKGAAGVMFTIDTESGFDQVVFITSSYGLGETVVQGAVNPDE
FYVHKPMLAAGNRAVIRRNLGSKLIQMVFASPEEKKASGKLVKTTDVPTEQRNRYSLTDAEVEQLARYALLIEKHYGRPM
DIEWGKDGTDGQLYILQARPETVKSQQQGQAEQKFKLKGTGTVLAEGRAIGQKIGTGPVRLVSDIAEMDKVQPGDVLVTD
MTDPNWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATSLLKDGTLVTVSCAEGDTGRIYDGLLETEVTEVQ
RGEMPKISTKIMMNVGNPQLAFDFCQLPNEGVGLARLEFIINNNIGVHPKAILDYPAVDADLKKAVESVARGHASPRAFY
VDKVAEGVATIAAAFWPKPVIVRLSDFKSNEYRKLIGGSRYEPEEENPMLGFRGAARYISQDFGEAFAMECEALKRVRND
MGLTNVQVMVPFVRTLGQADRVTKLLAEHGLKRGENELKLIMMCEVPSNAVLADEFLQFFDGFSVGSNDLTQLTLGLDRD
SGLELLAADFDERDPAVQALLSRAIEACKRQGKYVGICGQGPSDHPDFALWLAEQGISSISLNPDSVIATWQKLAG

Sequences:

>Translated_796_residues
MSALFEPTALVVPFENLRMTDVESVGGKNASLGEMISQLPDGVRVPTGFATTAHAFRQFLAHDGLAQKISDRLKTLDTED
VRALAAAGAEIRAMVEAQPFPADLEKAIRDAFATLCGGNAEACFAVRSSATAEDLPDASFAGQQETFLNVVGIEDVLHKM
KEVFASLYNDRAISYRVHKGFAHDVVALSAGVQRMVRSDKGAAGVMFTIDTESGFDQVVFITSSYGLGETVVQGAVNPDE
FYVHKPMLAAGNRAVIRRNLGSKLIQMVFASPEEKKASGKLVKTTDVPTEQRNRYSLTDAEVEQLARYALLIEKHYGRPM
DIEWGKDGTDGQLYILQARPETVKSQQQGQAEQKFKLKGTGTVLAEGRAIGQKIGTGPVRLVSDIAEMDKVQPGDVLVTD
MTDPNWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATSLLKDGTLVTVSCAEGDTGRIYDGLLETEVTEVQ
RGEMPKISTKIMMNVGNPQLAFDFCQLPNEGVGLARLEFIINNNIGVHPKAILDYPAVDADLKKAVESVARGHASPRAFY
VDKVAEGVATIAAAFWPKPVIVRLSDFKSNEYRKLIGGSRYEPEEENPMLGFRGAARYISQDFGEAFAMECEALKRVRND
MGLTNVQVMVPFVRTLGQADRVTKLLAEHGLKRGENELKLIMMCEVPSNAVLADEFLQFFDGFSVGSNDLTQLTLGLDRD
SGLELLAADFDERDPAVQALLSRAIEACKRQGKYVGICGQGPSDHPDFALWLAEQGISSISLNPDSVIATWQKLAG
>Mature_795_residues
SALFEPTALVVPFENLRMTDVESVGGKNASLGEMISQLPDGVRVPTGFATTAHAFRQFLAHDGLAQKISDRLKTLDTEDV
RALAAAGAEIRAMVEAQPFPADLEKAIRDAFATLCGGNAEACFAVRSSATAEDLPDASFAGQQETFLNVVGIEDVLHKMK
EVFASLYNDRAISYRVHKGFAHDVVALSAGVQRMVRSDKGAAGVMFTIDTESGFDQVVFITSSYGLGETVVQGAVNPDEF
YVHKPMLAAGNRAVIRRNLGSKLIQMVFASPEEKKASGKLVKTTDVPTEQRNRYSLTDAEVEQLARYALLIEKHYGRPMD
IEWGKDGTDGQLYILQARPETVKSQQQGQAEQKFKLKGTGTVLAEGRAIGQKIGTGPVRLVSDIAEMDKVQPGDVLVTDM
TDPNWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATSLLKDGTLVTVSCAEGDTGRIYDGLLETEVTEVQR
GEMPKISTKIMMNVGNPQLAFDFCQLPNEGVGLARLEFIINNNIGVHPKAILDYPAVDADLKKAVESVARGHASPRAFYV
DKVAEGVATIAAAFWPKPVIVRLSDFKSNEYRKLIGGSRYEPEEENPMLGFRGAARYISQDFGEAFAMECEALKRVRNDM
GLTNVQVMVPFVRTLGQADRVTKLLAEHGLKRGENELKLIMMCEVPSNAVLADEFLQFFDGFSVGSNDLTQLTLGLDRDS
GLELLAADFDERDPAVQALLSRAIEACKRQGKYVGICGQGPSDHPDFALWLAEQGISSISLNPDSVIATWQKLAG

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=789, Percent_Identity=65.3992395437262, Blast_Score=1063, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=453, Percent_Identity=25.3863134657837, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI48994992, Length=400, Percent_Identity=26, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788726, Length=193, Percent_Identity=31.0880829015544, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1789193, Length=391, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564524, Length=321, Percent_Identity=26.4797507788162, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 86358; Mature: 86227

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFEPTALVVPFENLRMTDVESVGGKNASLGEMISQLPDGVRVPTGFATTAHAFRQFL
CCCCCCCCEEEEECCCCCCCCHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AHDGLAQKISDRLKTLDTEDVRALAAAGAEIRAMVEAQPFPADLEKAIRDAFATLCGGNA
HCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCC
EACFAVRSSATAEDLPDASFAGQQETFLNVVGIEDVLHKMKEVFASLYNDRAISYRVHKG
CEEEEECCCCCHHCCCCCCCCCCHHHHHEEECHHHHHHHHHHHHHHHHCCCEEEEEECCC
FAHDVVALSAGVQRMVRSDKGAAGVMFTIDTESGFDQVVFITSSYGLGETVVQGAVNPDE
CHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHCCCCCCC
FYVHKPMLAAGNRAVIRRNLGSKLIQMVFASPEEKKASGKLVKTTDVPTEQRNRYSLTDA
EEEECCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCCCCCCCHH
EVEQLARYALLIEKHYGRPMDIEWGKDGTDGQLYILQARPETVKSQQQGQAEQKFKLKGT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCHHEEEECCC
GTVLAEGRAIGQKIGTGPVRLVSDIAEMDKVQPGDVLVTDMTDPNWEPVMKRASAIVTNR
CEEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCC
GGRTCHAAIIARELGIPAVVGCGDATSLLKDGTLVTVSCAEGDTGRIYDGLLETEVTEVQ
CCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
RGEMPKISTKIMMNVGNPQLAFDFCQLPNEGVGLARLEFIINNNIGVHPKAILDYPAVDA
CCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCH
DLKKAVESVARGHASPRAFYVDKVAEGVATIAAAFWPKPVIVRLSDFKSNEYRKLIGGSR
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCC
YEPEEENPMLGFRGAARYISQDFGEAFAMECEALKRVRNDMGLTNVQVMVPFVRTLGQAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
RVTKLLAEHGLKRGENELKLIMMCEVPSNAVLADEFLQFFDGFSVGSNDLTQLTLGLDRD
HHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
SGLELLAADFDERDPAVQALLSRAIEACKRQGKYVGICGQGPSDHPDFALWLAEQGISSI
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEHHCCCCEE
SLNPDSVIATWQKLAG
CCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SALFEPTALVVPFENLRMTDVESVGGKNASLGEMISQLPDGVRVPTGFATTAHAFRQFL
CCCCCCCEEEEECCCCCCCCHHHCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AHDGLAQKISDRLKTLDTEDVRALAAAGAEIRAMVEAQPFPADLEKAIRDAFATLCGGNA
HCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCC
EACFAVRSSATAEDLPDASFAGQQETFLNVVGIEDVLHKMKEVFASLYNDRAISYRVHKG
CEEEEECCCCCHHCCCCCCCCCCHHHHHEEECHHHHHHHHHHHHHHHHCCCEEEEEECCC
FAHDVVALSAGVQRMVRSDKGAAGVMFTIDTESGFDQVVFITSSYGLGETVVQGAVNPDE
CHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHCCCCCCC
FYVHKPMLAAGNRAVIRRNLGSKLIQMVFASPEEKKASGKLVKTTDVPTEQRNRYSLTDA
EEEECCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCCCCCCCCCHH
EVEQLARYALLIEKHYGRPMDIEWGKDGTDGQLYILQARPETVKSQQQGQAEQKFKLKGT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCHHEEEECCC
GTVLAEGRAIGQKIGTGPVRLVSDIAEMDKVQPGDVLVTDMTDPNWEPVMKRASAIVTNR
CEEEECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCC
GGRTCHAAIIARELGIPAVVGCGDATSLLKDGTLVTVSCAEGDTGRIYDGLLETEVTEVQ
CCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
RGEMPKISTKIMMNVGNPQLAFDFCQLPNEGVGLARLEFIINNNIGVHPKAILDYPAVDA
CCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHCCCCCCCH
DLKKAVESVARGHASPRAFYVDKVAEGVATIAAAFWPKPVIVRLSDFKSNEYRKLIGGSR
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCC
YEPEEENPMLGFRGAARYISQDFGEAFAMECEALKRVRNDMGLTNVQVMVPFVRTLGQAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
RVTKLLAEHGLKRGENELKLIMMCEVPSNAVLADEFLQFFDGFSVGSNDLTQLTLGLDRD
HHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCC
SGLELLAADFDERDPAVQALLSRAIEACKRQGKYVGICGQGPSDHPDFALWLAEQGISSI
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEHHCCCCEE
SLNPDSVIATWQKLAG
CCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]