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The map label for this gene is aspC [H]

Identifier: 120609944

GI number: 120609944

Start: 1381326

End: 1382498

Strand: Direct

Name: aspC [H]

Synonym: Aave_1257

Alternate gene names: 120609944

Gene position: 1381326-1382498 (Clockwise)

Preceding gene: 120609942

Following gene: 120609945

Centisome position: 25.81

GC content: 71.27

Gene sequence:

>1173_bases
ATGCGCCATACCCTCGTCCACCTCGAAGAATCCAAGATCCGCGAAGTCGCCAACGCCGGAATGGGTCGGCCCGACGTCCT
CGCGTTCTGGTTCGGCGAAAGCGACGAGGCCACCCCGGACGTGGTGAACGAGGCCGCCATCGCCTCGCTGCGCGCTGGTG
AAACCTTCTATTCCCAGAACCTCGGCCTGCCCGCGTTGCGCGAGGCCATTGCCGCCTACATGGCGCGACTGCACGGCCCG
GCCATCGATGCCGGACGCATCGCCGTCACTTCCGGCGGGGTCAGCGGCCTCATGCTGGCGGTGCAGGCCCTGGTGGACCC
GGGCGACGAGGTGGTCGCCGTCACGCCCGTCTGGCCCAATCTCGTGGCGCAGCCGCGCATCCTGGGCGCGCGCCTGCAGT
GCCTGCCGCTGCGCCCGCGCGAGGACGGCGCCTGGGCGCTGGACATGGACGCCCTGAAGCGCGCCGTGACGCCGGCCACG
CGGCTGCTGGTGGTGAACGCCCCGAACAATCCGACGGGCTGGACGCTGTCGGCGGCCGAGCAGCGCGAGATTCTGGAGCA
CTGCCGCGCCACGGGCACCTGGATCCTGGCCGACGAGGTCTATGAGCGCCTGTACTACGAGCCGACGCCCCACGGCTGCG
CGCCGAGCTTCCTCGACCTCGCCGCGTCGCAGGACCGCCTGGTGGTGGTGCACAGCTTCTCCAAGAGCTTCCTGATGACG
GGCTGGCGGCTGGGCTGGCTCGTCCTGCCGCCGGCACTGGCAGCCCACATGGGCAAGCTGATCGAGTTCAACACCTCGTG
CGTGAGCGTCTTCACGCAGCGCGGCGGCATCGCCGCGCTGCAGCACGAGGGGGAAATCGTCCCGCGCGTCACCGCCCACA
TGCGCCTGTGCCGCGACACCCTGCTGCCGCTGCTGCAGGCGGCGCCCGGCGTGCATGCCCATGCGGCCAGCGGTGGCATG
TACGCCTTCTTCCGCATGGACGGCCACGGCGACGCGATGGCCACCGCCAAGCGCCTCGTTGCGGAGGCCGGCCTGGGGCT
GGCGCCCGGCAATGCCTTCGGCCCGGAAGGGGAGGGCTGGCTGCGCTGGTGCTTCGCCTCGCGCGACCCCGCGCGGCTGG
TGGAAGGGGTGGCGCGCCTGCGGAAATGGCTCGAAAAGGCCGGCGCGGTATAA

Upstream 100 bases:

>100_bases
GCCCACGAGCACCACCACGGCGGCGCGGGAAGGGTTTGTCTTCGATTGCATGGAAGTTCCTCCGGCTCGACAATGTAGCG
CTTCGCCGCCCCGACACTCC

Downstream 100 bases:

>100_bases
TCCCAGGGTTTTGCATGGTGCAAGACGCACGCCGCCGGCCGTTCCAGCCCGCGGCGCAAGTCAAAACCTGGGGCCGCAGC
CTCGCCACGCGCGATGCCCG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRHTLVHLEESKIREVANAGMGRPDVLAFWFGESDEATPDVVNEAAIASLRAGETFYSQNLGLPALREAIAAYMARLHGP
AIDAGRIAVTSGGVSGLMLAVQALVDPGDEVVAVTPVWPNLVAQPRILGARLQCLPLRPREDGAWALDMDALKRAVTPAT
RLLVVNAPNNPTGWTLSAAEQREILEHCRATGTWILADEVYERLYYEPTPHGCAPSFLDLAASQDRLVVVHSFSKSFLMT
GWRLGWLVLPPALAAHMGKLIEFNTSCVSVFTQRGGIAALQHEGEIVPRVTAHMRLCRDTLLPLLQAAPGVHAHAASGGM
YAFFRMDGHGDAMATAKRLVAEAGLGLAPGNAFGPEGEGWLRWCFASRDPARLVEGVARLRKWLEKAGAV

Sequences:

>Translated_390_residues
MRHTLVHLEESKIREVANAGMGRPDVLAFWFGESDEATPDVVNEAAIASLRAGETFYSQNLGLPALREAIAAYMARLHGP
AIDAGRIAVTSGGVSGLMLAVQALVDPGDEVVAVTPVWPNLVAQPRILGARLQCLPLRPREDGAWALDMDALKRAVTPAT
RLLVVNAPNNPTGWTLSAAEQREILEHCRATGTWILADEVYERLYYEPTPHGCAPSFLDLAASQDRLVVVHSFSKSFLMT
GWRLGWLVLPPALAAHMGKLIEFNTSCVSVFTQRGGIAALQHEGEIVPRVTAHMRLCRDTLLPLLQAAPGVHAHAASGGM
YAFFRMDGHGDAMATAKRLVAEAGLGLAPGNAFGPEGEGWLRWCFASRDPARLVEGVARLRKWLEKAGAV
>Mature_390_residues
MRHTLVHLEESKIREVANAGMGRPDVLAFWFGESDEATPDVVNEAAIASLRAGETFYSQNLGLPALREAIAAYMARLHGP
AIDAGRIAVTSGGVSGLMLAVQALVDPGDEVVAVTPVWPNLVAQPRILGARLQCLPLRPREDGAWALDMDALKRAVTPAT
RLLVVNAPNNPTGWTLSAAEQREILEHCRATGTWILADEVYERLYYEPTPHGCAPSFLDLAASQDRLVVVHSFSKSFLMT
GWRLGWLVLPPALAAHMGKLIEFNTSCVSVFTQRGGIAALQHEGEIVPRVTAHMRLCRDTLLPLLQAAPGVHAHAASGGM
YAFFRMDGHGDAMATAKRLVAEAGLGLAPGNAFGPEGEGWLRWCFASRDPARLVEGVARLRKWLEKAGAV

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=391, Percent_Identity=25.8312020460358, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI56713254, Length=391, Percent_Identity=25.8312020460358, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI95147551, Length=405, Percent_Identity=25.679012345679, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI169881279, Length=405, Percent_Identity=25.679012345679, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19263340, Length=344, Percent_Identity=26.453488372093, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI215599424, Length=376, Percent_Identity=26.063829787234, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4507369, Length=358, Percent_Identity=22.3463687150838, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI7705897, Length=346, Percent_Identity=26.0115606936416, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI33469970, Length=346, Percent_Identity=26.0115606936416, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI169881281, Length=264, Percent_Identity=23.4848484848485, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=25.6198347107438, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786816, Length=356, Percent_Identity=26.685393258427, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788627, Length=358, Percent_Identity=27.6536312849162, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787710, Length=316, Percent_Identity=27.2151898734177, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790797, Length=189, Percent_Identity=30.6878306878307, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=217, Percent_Identity=25.8064516129032, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=244, Percent_Identity=26.6393442622951, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=244, Percent_Identity=26.6393442622951, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=362, Percent_Identity=20.9944751381215, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=204, Percent_Identity=25.9803921568627, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=23.5142118863049, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=23.5142118863049, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=23.5142118863049, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=23.5142118863049, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI18859735, Length=213, Percent_Identity=28.169014084507, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42067; Mature: 42067

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHTLVHLEESKIREVANAGMGRPDVLAFWFGESDEATPDVVNEAAIASLRAGETFYSQN
CCCEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHCC
LGLPALREAIAAYMARLHGPAIDAGRIAVTSGGVSGLMLAVQALVDPGDEVVAVTPVWPN
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCC
LVAQPRILGARLQCLPLRPREDGAWALDMDALKRAVTPATRLLVVNAPNNPTGWTLSAAE
HHCCCCHHCCCEEEEECCCCCCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCEEECHHH
QREILEHCRATGTWILADEVYERLYYEPTPHGCAPSFLDLAASQDRLVVVHSFSKSFLMT
HHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHC
GWRLGWLVLPPALAAHMGKLIEFNTSCVSVFTQRGGIAALQHEGEIVPRVTAHMRLCRDT
CHHCCCEECCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
LLPLLQAAPGVHAHAASGGMYAFFRMDGHGDAMATAKRLVAEAGLGLAPGNAFGPEGEGW
HHHHHHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
LRWCFASRDPARLVEGVARLRKWLEKAGAV
EEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHTLVHLEESKIREVANAGMGRPDVLAFWFGESDEATPDVVNEAAIASLRAGETFYSQN
CCCEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHCC
LGLPALREAIAAYMARLHGPAIDAGRIAVTSGGVSGLMLAVQALVDPGDEVVAVTPVWPN
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCC
LVAQPRILGARLQCLPLRPREDGAWALDMDALKRAVTPATRLLVVNAPNNPTGWTLSAAE
HHCCCCHHCCCEEEEECCCCCCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCEEECHHH
QREILEHCRATGTWILADEVYERLYYEPTPHGCAPSFLDLAASQDRLVVVHSFSKSFLMT
HHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHC
GWRLGWLVLPPALAAHMGKLIEFNTSCVSVFTQRGGIAALQHEGEIVPRVTAHMRLCRDT
CHHCCCEECCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
LLPLLQAAPGVHAHAASGGMYAFFRMDGHGDAMATAKRLVAEAGLGLAPGNAFGPEGEGW
HHHHHHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
LRWCFASRDPARLVEGVARLRKWLEKAGAV
EEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]