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The map label for this gene is ycfF [C]

Identifier: 120609745

GI number: 120609745

Start: 1155257

End: 1155655

Strand: Direct

Name: ycfF [C]

Synonym: Aave_1052

Alternate gene names: 120609745

Gene position: 1155257-1155655 (Clockwise)

Preceding gene: 120609744

Following gene: 120609746

Centisome position: 21.58

GC content: 63.91

Gene sequence:

>399_bases
ATGTCTGACGCGTTTCCAGACCCGTTTTCTCTCTCCCACGCCATGCACGATCCCGACTGCCTCTTCTGCAAGATCATCGC
CGGCCAGATCCCCTCGCGGAAGGTCTATGAGGACGACGAAGTCTTCGCCTTCCACGACATCCACCCCGGCGCACCCGTCC
ACTTCCTCATGGTGCCCAAGCAGCACGTGCACTCCATGGCCGGCGTGACCGATGCCCATGCCGGCGTGCTCGGCCGCATG
ATGGTGCTGGCGCCGAAGCTGGCGCTGGAGCAGGGCTGCAATCCCTATCCGGACGGCGGATTCCGCATCGTGGTAAATAC
CGGTACTGAGGGTGGCCAGGAAGTGCACCACCTCCATCTGCACGTGATGGGCGGTCCCCGCCCCTGGCTGAAGGGCTGA

Upstream 100 bases:

>100_bases
GTGCGCCAGCTCTTCGCGCTCGGCCGCGCGGCCGGCCAGGCCTGGATCGCCCGCCACCACGGGGACGTCGGGGTGCGGCC
CACGGTGAACATCGCCGACA

Downstream 100 bases:

>100_bases
AACCGCCCCCGGCGGCGGTCAGGGATATGAAACTTCCGTGACTTGCGCCGAGTCTAGAATGGGCCGTATTCGTTAGGAGA
TTTCCATGGGTTCCTTTTCC

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MSDAFPDPFSLSHAMHDPDCLFCKIIAGQIPSRKVYEDDEVFAFHDIHPGAPVHFLMVPKQHVHSMAGVTDAHAGVLGRM
MVLAPKLALEQGCNPYPDGGFRIVVNTGTEGGQEVHHLHLHVMGGPRPWLKG

Sequences:

>Translated_132_residues
MSDAFPDPFSLSHAMHDPDCLFCKIIAGQIPSRKVYEDDEVFAFHDIHPGAPVHFLMVPKQHVHSMAGVTDAHAGVLGRM
MVLAPKLALEQGCNPYPDGGFRIVVNTGTEGGQEVHHLHLHVMGGPRPWLKG
>Mature_131_residues
SDAFPDPFSLSHAMHDPDCLFCKIIAGQIPSRKVYEDDEVFAFHDIHPGAPVHFLMVPKQHVHSMAGVTDAHAGVLGRMM
VLAPKLALEQGCNPYPDGGFRIVVNTGTEGGQEVHHLHLHVMGGPRPWLKG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=107, Percent_Identity=45.7943925233645, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI14211923, Length=106, Percent_Identity=34.9056603773585, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787346, Length=111, Percent_Identity=43.2432432432432, Blast_Score=92, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17506713, Length=116, Percent_Identity=43.1034482758621, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320078, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28574010, Length=112, Percent_Identity=40.1785714285714, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581222, Length=112, Percent_Identity=40.1785714285714, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 14423; Mature: 14292

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAFPDPFSLSHAMHDPDCLFCKIIAGQIPSRKVYEDDEVFAFHDIHPGAPVHFLMVPK
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCH
QHVHSMAGVTDAHAGVLGRMMVLAPKLALEQGCNPYPDGGFRIVVNTGTEGGQEVHHLHL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEE
HVMGGPRPWLKG
EEECCCCCCCCC
>Mature Secondary Structure 
SDAFPDPFSLSHAMHDPDCLFCKIIAGQIPSRKVYEDDEVFAFHDIHPGAPVHFLMVPK
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCH
QHVHSMAGVTDAHAGVLGRMMVLAPKLALEQGCNPYPDGGFRIVVNTGTEGGQEVHHLHL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEEE
HVMGGPRPWLKG
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]