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The map label for this gene is lpxP [H]

Identifier: 120609674

GI number: 120609674

Start: 1076242

End: 1077105

Strand: Direct

Name: lpxP [H]

Synonym: Aave_0980

Alternate gene names: 120609674

Gene position: 1076242-1077105 (Clockwise)

Preceding gene: 120609667

Following gene: 120609675

Centisome position: 20.11

GC content: 72.92

Gene sequence:

>864_bases
ATGCCCCCCGCGTTCCGCTTCTTCGCCCGATGGCCATTGCCTGCGCTCCATGCGCTGGGCGCGGTGCTGGGCTGGATCGC
GTTCCTCGCGTCGCCCACCTACCGCCGCCGCTTCCTCGCCAATGCTCGCCTGGCCGGCTATCCCTTCGTGCGCGTGCGCG
CCGCGGTGGCCCACGCGGGCCGCATGGCGGCCGAGCTGCCGCGCCTGTGGCTGCGCGCCGAGGCGCCGCCGTTCCGCATG
GAGGGGGCGGAGTGCGTGGAACAGGCCTGGGCGGCTGGCCGGGGCATCGTCTTCCTCACGCCGCACATCGGCTGCTTCGA
GCTGTCGGTGCAGATCGCGGCGCGGCGCTGGGCCGGGGAGCACGGCCCCGTTACGGTACTCTACCGGCCCGCCCGGCAGG
CCTGGCTCGCGGAACTCATGCGCACGGCGCGCGACCGGCCAGGGATCCGGGCAGTGCCCACCACGCTCTCGGGCGTGCGG
CAGATGATCAAGGCGCTGCGCCGCGGCGAGGCCGTGGGCCTGCTGCCCGACCAGGTGCCGCCCGAAGGGCAGGGTCTTTG
GGCGCCGTTCTTCGGACTGCCGGCCTATACGATGACGCTCGCCGCCCGCCTGGTGCAGCAGACAGGCGCCACGGTGGTCC
TGGCACGCTGCGAGCGCCTGCCGCGCGGCCGCGGCTACGTGCTGCACCTCGAGCCCCTGGCCGAGCCGCTTTCCCCTTCC
CTCGAAACCGCCGTCCTGCAGATCAACCAATCCATGGAACGCATCATCCGACACTCTCCCGACCAATACCTCTGGGGCTA
CGGGCGCTACAAGCAACCGCGGGCCGAGGCATCCACGCCGGCCGTGCCGGGAGCGGACGCATGA

Upstream 100 bases:

>100_bases
AGCCGTGGCGAACGCTTTAGCAGAGTTGTTTAACGTCGCCCTGCAAGTTGCTCATTTAACTCAGCGACCCCGCCATTCTA
CCGACACGGATCTGTCACCG

Downstream 100 bases:

>100_bases
CGGCGGGGCGCTTCAATCTCGCCTGCATGCGCGTGCTCGCCCGCCTGCCCCTGCCCGTGCTGCGGGCCCTGGGCTGGGTG
CTGGGGCAGGTGATCTACGT

Product: lipid A biosynthesis acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MPPAFRFFARWPLPALHALGAVLGWIAFLASPTYRRRFLANARLAGYPFVRVRAAVAHAGRMAAELPRLWLRAEAPPFRM
EGAECVEQAWAAGRGIVFLTPHIGCFELSVQIAARRWAGEHGPVTVLYRPARQAWLAELMRTARDRPGIRAVPTTLSGVR
QMIKALRRGEAVGLLPDQVPPEGQGLWAPFFGLPAYTMTLAARLVQQTGATVVLARCERLPRGRGYVLHLEPLAEPLSPS
LETAVLQINQSMERIIRHSPDQYLWGYGRYKQPRAEASTPAVPGADA

Sequences:

>Translated_287_residues
MPPAFRFFARWPLPALHALGAVLGWIAFLASPTYRRRFLANARLAGYPFVRVRAAVAHAGRMAAELPRLWLRAEAPPFRM
EGAECVEQAWAAGRGIVFLTPHIGCFELSVQIAARRWAGEHGPVTVLYRPARQAWLAELMRTARDRPGIRAVPTTLSGVR
QMIKALRRGEAVGLLPDQVPPEGQGLWAPFFGLPAYTMTLAARLVQQTGATVVLARCERLPRGRGYVLHLEPLAEPLSPS
LETAVLQINQSMERIIRHSPDQYLWGYGRYKQPRAEASTPAVPGADA
>Mature_286_residues
PPAFRFFARWPLPALHALGAVLGWIAFLASPTYRRRFLANARLAGYPFVRVRAAVAHAGRMAAELPRLWLRAEAPPFRME
GAECVEQAWAAGRGIVFLTPHIGCFELSVQIAARRWAGEHGPVTVLYRPARQAWLAELMRTARDRPGIRAVPTTLSGVRQ
MIKALRRGEAVGLLPDQVPPEGQGLWAPFFGLPAYTMTLAARLVQQTGATVVLARCERLPRGRGYVLHLEPLAEPLSPSL
ETAVLQINQSMERIIRHSPDQYLWGYGRYKQPRAEASTPAVPGADA

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=205, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787292, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 31751; Mature: 31620

Theoretical pI: Translated: 11.30; Mature: 11.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAFRFFARWPLPALHALGAVLGWIAFLASPTYRRRFLANARLAGYPFVRVRAAVAHAG
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RMAAELPRLWLRAEAPPFRMEGAECVEQAWAAGRGIVFLTPHIGCFELSVQIAARRWAGE
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCC
HGPVTVLYRPARQAWLAELMRTARDRPGIRAVPTTLSGVRQMIKALRRGEAVGLLPDQVP
CCCEEEEECCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCEECCCCCCCC
PEGQGLWAPFFGLPAYTMTLAARLVQQTGATVVLARCERLPRGRGYVLHLEPLAEPLSPS
CCCCCCCCHHHCCHHHHHHHHHHHHHHCCCHHEEHHHHHCCCCCCEEEEEHHHCCCCCCH
LETAVLQINQSMERIIRHSPDQYLWGYGRYKQPRAEASTPAVPGADA
HHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPAFRFFARWPLPALHALGAVLGWIAFLASPTYRRRFLANARLAGYPFVRVRAAVAHAG
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RMAAELPRLWLRAEAPPFRMEGAECVEQAWAAGRGIVFLTPHIGCFELSVQIAARRWAGE
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCC
HGPVTVLYRPARQAWLAELMRTARDRPGIRAVPTTLSGVRQMIKALRRGEAVGLLPDQVP
CCCEEEEECCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCEECCCCCCCC
PEGQGLWAPFFGLPAYTMTLAARLVQQTGATVVLARCERLPRGRGYVLHLEPLAEPLSPS
CCCCCCCCHHHCCHHHHHHHHHHHHHHCCCHHEEHHHHHCCCCCCEEEEEHHHCCCCCCH
LETAVLQINQSMERIIRHSPDQYLWGYGRYKQPRAEASTPAVPGADA
HHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]