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The map label for this gene is engD [H]

Identifier: 120609581

GI number: 120609581

Start: 963935

End: 965029

Strand: Direct

Name: engD [H]

Synonym: Aave_0887

Alternate gene names: 120609581

Gene position: 963935-965029 (Clockwise)

Preceding gene: 120609580

Following gene: 120609583

Centisome position: 18.01

GC content: 66.94

Gene sequence:

>1095_bases
ATGAGCCTGAAATGCGGCATCGTGGGCCTGCCCAACGTCGGCAAGTCCACCCTCTTCAACGCCCTGACCAAGGCCGGCAT
CGCGGCCGAGAACTACCCTTTCTGCACCATCGAGCCCAACACCGGCGTGGTGGAAGTGCCCGATCCCCGCCTGCAGCAGC
TGGCCGGCATCATCACCCCCGAGCGCATCGTGCCGGCCATCGTCGAGTTCGTGGACATCGCCGGCCTGGTGGCGGGCGCC
TCCAAGGGCGAAGGCCTGGGCAACCAGTTCCTGGCCCACATCCGCGAGACCGACGCCATCGTCAACGTGGTGCGCTGCTT
CGAGGATCCGAACGTGATCCACGTGGCCGGCCGCGTGGACCCGATCGCCGACATCGAGGTCATCCAGACCGAGCTGTGCC
TGGCCGACCTGGCCACGGTGGAGAAAGCCCTCAACCGCTACAGCAAGGCCGCCAAGAGCGGCAATGACAAGGAAGCCGCC
AAGCTGGTCTCGCTGCTCACGCCCATCCAGGCCGCGCTCGACCAGGGCAAGCCCGCGCGCACGGTGCCCGTCAGCAAGGA
AGACGCGCCCCTGCTCAAGCAGTTCTGCCTCATCACCGCCAAGCCGGCGATGTTCGTCGGCAACGTGGCCGAGGACGGCT
TCGAGAACAACCCGCTGCTCGACCGCCTGAAGGAATACGCCGCCGCCCAGAACGCGCCCGTCGTGGCCATCTGCGCCAAG
ATCGAATCCGAGATGAGCGAGATGAGCGACGAGGACCGCGACATGTTCCTGGCCGAGATGGGCCAGGACGAGCCCGGCCT
GAACCGCCTGATCCGCGCCGGCTTCAGGCTGCTGGGCCTGCAGACCTACTTCACCGCCGGCGTGAAGGAAGTGCGCGCCT
GGACCGTGCCCGTGGGCGCCACCGCGCCCCAGGCCGCCGGCGTGATCCACGGCGACTTCGAGCGCGGCTTCATCCGCGCC
CAGACCATCGCCTTCGACGACTTCATCGCCTTCAAGGGCGAGCAGGGCGCGAAGGACGCGGGCAAGATGCGGGCGGAAGG
CAAGGAATACGTCGTCAAGGATGGGGACGTGATGAACTTCCTGTTCAACGTCTGA

Upstream 100 bases:

>100_bases
CGACTGGCATTTCGACTGACCCTCCGCGCCGGGCGGGCCGGCAGGGACACGGCCGCCCGGTAAAATCGCCGGTTTTCCCC
CGAACCCTGAAAGCCCCGCC

Downstream 100 bases:

>100_bases
GCCAAGGGGCATTGCAGGAGTTGGAACGGCTTCTTGATGGATTGCCACAGGCAAGAAAGCCGCCCCGCAGGCCAATGCCA
GTCAGTTGAACCCTGACTGG

Product: GTP-binding protein YchF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNTGVVEVPDPRLQQLAGIITPERIVPAIVEFVDIAGLVAGA
SKGEGLGNQFLAHIRETDAIVNVVRCFEDPNVIHVAGRVDPIADIEVIQTELCLADLATVEKALNRYSKAAKSGNDKEAA
KLVSLLTPIQAALDQGKPARTVPVSKEDAPLLKQFCLITAKPAMFVGNVAEDGFENNPLLDRLKEYAAAQNAPVVAICAK
IESEMSEMSDEDRDMFLAEMGQDEPGLNRLIRAGFRLLGLQTYFTAGVKEVRAWTVPVGATAPQAAGVIHGDFERGFIRA
QTIAFDDFIAFKGEQGAKDAGKMRAEGKEYVVKDGDVMNFLFNV

Sequences:

>Translated_364_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNTGVVEVPDPRLQQLAGIITPERIVPAIVEFVDIAGLVAGA
SKGEGLGNQFLAHIRETDAIVNVVRCFEDPNVIHVAGRVDPIADIEVIQTELCLADLATVEKALNRYSKAAKSGNDKEAA
KLVSLLTPIQAALDQGKPARTVPVSKEDAPLLKQFCLITAKPAMFVGNVAEDGFENNPLLDRLKEYAAAQNAPVVAICAK
IESEMSEMSDEDRDMFLAEMGQDEPGLNRLIRAGFRLLGLQTYFTAGVKEVRAWTVPVGATAPQAAGVIHGDFERGFIRA
QTIAFDDFIAFKGEQGAKDAGKMRAEGKEYVVKDGDVMNFLFNV
>Mature_363_residues
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNTGVVEVPDPRLQQLAGIITPERIVPAIVEFVDIAGLVAGAS
KGEGLGNQFLAHIRETDAIVNVVRCFEDPNVIHVAGRVDPIADIEVIQTELCLADLATVEKALNRYSKAAKSGNDKEAAK
LVSLLTPIQAALDQGKPARTVPVSKEDAPLLKQFCLITAKPAMFVGNVAEDGFENNPLLDRLKEYAAAQNAPVVAICAKI
ESEMSEMSDEDRDMFLAEMGQDEPGLNRLIRAGFRLLGLQTYFTAGVKEVRAWTVPVGATAPQAAGVIHGDFERGFIRAQ
TIAFDDFIAFKGEQGAKDAGKMRAEGKEYVVKDGDVMNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=42.2764227642276, Blast_Score=295, Evalue=6e-80,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=34.8017621145374, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=65.3846153846154, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1789574, Length=141, Percent_Identity=31.9148936170213, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=40.4371584699454, Blast_Score=288, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=40.5405405405405, Blast_Score=257, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=33.3333333333333, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6321649, Length=163, Percent_Identity=37.4233128834356, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=41.41689373297, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=41.41689373297, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=41.41689373297, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=38.719512195122, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24585318, Length=174, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39104; Mature: 38973

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNTGVVEVPDPRLQQLAGIITP
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHCCCH
ERIVPAIVEFVDIAGLVAGASKGEGLGNQFLAHIRETDAIVNVVRCFEDPNVIHVAGRVD
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PIADIEVIQTELCLADLATVEKALNRYSKAAKSGNDKEAAKLVSLLTPIQAALDQGKPAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TVPVSKEDAPLLKQFCLITAKPAMFVGNVAEDGFENNPLLDRLKEYAAAQNAPVVAICAK
CCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEHHHH
IESEMSEMSDEDRDMFLAEMGQDEPGLNRLIRAGFRLLGLQTYFTAGVKEVRAWTVPVGA
HHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
TAPQAAGVIHGDFERGFIRAQTIAFDDFIAFKGEQGAKDAGKMRAEGKEYVVKDGDVMNF
CCCCCCCCEECCCCCCEEEEHHEEHHHHHEECCCCCCCHHHHHHCCCCEEEECCCHHHHH
LFNV
HHCC
>Mature Secondary Structure 
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNTGVVEVPDPRLQQLAGIITP
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHCCCH
ERIVPAIVEFVDIAGLVAGASKGEGLGNQFLAHIRETDAIVNVVRCFEDPNVIHVAGRVD
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PIADIEVIQTELCLADLATVEKALNRYSKAAKSGNDKEAAKLVSLLTPIQAALDQGKPAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TVPVSKEDAPLLKQFCLITAKPAMFVGNVAEDGFENNPLLDRLKEYAAAQNAPVVAICAK
CCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEHHHH
IESEMSEMSDEDRDMFLAEMGQDEPGLNRLIRAGFRLLGLQTYFTAGVKEVRAWTVPVGA
HHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
TAPQAAGVIHGDFERGFIRAQTIAFDDFIAFKGEQGAKDAGKMRAEGKEYVVKDGDVMNF
CCCCCCCCEECCCCCCEEEEHHEEHHHHHEECCCCCCCHHHHHHCCCCEEEECCCHHHHH
LFNV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]