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The map label for this gene is yciR [C]

Identifier: 120609349

GI number: 120609349

Start: 700888

End: 702861

Strand: Direct

Name: yciR [C]

Synonym: Aave_0649

Alternate gene names: 120609349

Gene position: 700888-702861 (Clockwise)

Preceding gene: 120609344

Following gene: 120609350

Centisome position: 13.09

GC content: 73.91

Gene sequence:

>1974_bases
ATGCATGAGGAGGAGGGGGGCGCCCCCCGCAACGCTCCCGGGAGGACGGCAGGCTGGCGGGTACCCGCCGCCCTGCTCCT
GTACGCTGCCGCCGGGCTGGCCTGGGTGGCCGGCGCGGAGGCGCTTTTGCCGGCCGGCAGCGTGCTGCGTGGAGCGCTGC
AGGCGGCCTTCGTACTGGCGCCGGCGGGCTGCGGCGTATGGGCGCTGCGGCGCTGGCGCGCGCGCGGCCGGGAGATCGCG
GTGCTGGCCCGCGGCGCCCTGCAGGCCGACGAGCGCCAGCGGCTCGCGGCCACGGTGGTGGACAACGCGGCCGAGGGCAT
GGTGGTGACCGATGCCGAGAGCCGCATCCTGTCGGTGAACGCGGCCTTCACGCGGCTCATGGGGTACGGCGAGGCGGAAC
TGCTGGGCCGCACGCCGCGGCTGTTCAAGTCGGGCCGCCACGGCCGCGCGTTCTACGAGGCCATGTGGGAAGAGCTGGGC
CGCACCGGGCACTGGCAGGGCGAGATCTGGAACCGCCGCAAGAACGGCGAGGTGTTCCCCGAGCGCATGTCGCTCTCCAG
CGTGCGCAATGCGCGCGGCGAGGTCACGCACTACGTGTGCCTGTTCACCGACATTTCCCAGGAGCACGAGCAGCGGCGCC
GGCTGGAGGTGATGGCCCATACCGACCCGCTCACGGGCCTGCCCAACCGCACGTTCTTCGCGCAGCAGCTCGAGGAAGCG
ATGGCGGACGCCCGCGCCCGCGGCGAACCGCTGGCGGTGCTGCTGGTCAACCTGGACCGGTTCAAGGATGTGAACGACAG
CTACGGCCACGCGGTGGGCGACCAGGTGCTGCGCCACATCGCCGCGCGCGTGCAGGAGGCGCTGCGGCCGGGCGACCTCG
CGGGGCGGCTGGCGGGCGACGAGATCGGCGTGATCGCGCGCCGCGTGGACGGGGCGCAGGGTGCGGTGGCGGCCGCGCGG
GCCCTGCTGGGCGCGCTGGCCGAACCCTGGCGCTCGCCCGACGGCTTCGAGGTGGTGGCCTCGGCCAGCGTGGGCATCTG
CCTGTTCCCGGACCATGGCGACACCGCCGATGCGCTGCTGCAGGGCGCCCATGCGGCGGTGTACGGCGCGCGCGAGCACG
GGCAGGGCGCATGGCATTTCTTCGACGAGAGCCTGACCCAGGCCGCGCGCGAGCGCCTCGCCCTGGAGGCGCGGCTGCGC
TCGGCGCTGGCCCAGGGGCACCTGCAACTGCACTACCAGCCGCAGGTGGACATCGCCTCCGGGCGCATCGTGGGCGCGGA
GGCGCTGGTGCGCTGGATCGACCCGGTGGAGGGCTCCATCGCGCCCGACCGCTTCATCCCGGTGGCCGAGCGCACGGGCA
TGATCGGCCCGCTGGGCGAATGGGTGATGCAGGAGGCCTGCCGCCAGGCCCAGGGCTGGCGCGAGGCCGGGCTGCCCGAG
GTCACGGTGGCGGTGAACGTCTCCCCGCGCCAGTTCCACCTGACCGACCTGGCGGGCTGCGCGGCCCTGGCGCTGGCGGA
TTCCGGCCTGCCGTCCACGCTGCTGGAACTGGAGCTCACCGAGGGTGCGCTGGCGGAGCGCCCCGAGGAGGCGCGCCAGG
TGCTGCTGCGGCTGCGTGGCCTGGGGCTGCGGCTGGCGATCGACGACTTCGGCACGGGCTACTCGTCGCTGGCGCACCTC
AAGCGTTTTCCGATCGATGTGCTGAAGATCGACAAGGGGTTCATCCGCGACCTGCCGCAGAGCGCGGACGACATGGCGAT
CTGCGCGGCCATCATCGCCATGGGGCACAGCCTGGGCCTGGCGGTGCTGGCCGAGGGCGTGGAGACGCCGGAGCAGCTGG
CGTTCCTGCGCAGCCGGGGCTGCGACCGCTACCAGGGCTACCTGTGCCGCAGGCCGGTGCCCTCGGCGGAGTTCGCGGCG
CTGCTGGCGCAGCAGGCCGCGGGAGTTGACGCGCCTTCGCCGGCCCAGCCATAA

Upstream 100 bases:

>100_bases
GCCCGAGCTTGTCCGGGCAGGAGAGGGTGAGAATATAGGCTTGGGTCATAGCGGGGCGATTGTCGCAGCACGGCCCGCAG
CAACGCGGAGCAAGGAATTG

Downstream 100 bases:

>100_bases
TCCGCCCGCTTTTTCCACGGCCCTTCGCTGACGGGGCCGCGAAAAACGCCGCGGCGGGCCCGGCCTGCCGCCCTCCGGCC
TCCTGCCGGCTTCTTCCCGC

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MHEEEGGAPRNAPGRTAGWRVPAALLLYAAAGLAWVAGAEALLPAGSVLRGALQAAFVLAPAGCGVWALRRWRARGREIA
VLARGALQADERQRLAATVVDNAAEGMVVTDAESRILSVNAAFTRLMGYGEAELLGRTPRLFKSGRHGRAFYEAMWEELG
RTGHWQGEIWNRRKNGEVFPERMSLSSVRNARGEVTHYVCLFTDISQEHEQRRRLEVMAHTDPLTGLPNRTFFAQQLEEA
MADARARGEPLAVLLVNLDRFKDVNDSYGHAVGDQVLRHIAARVQEALRPGDLAGRLAGDEIGVIARRVDGAQGAVAAAR
ALLGALAEPWRSPDGFEVVASASVGICLFPDHGDTADALLQGAHAAVYGAREHGQGAWHFFDESLTQAARERLALEARLR
SALAQGHLQLHYQPQVDIASGRIVGAEALVRWIDPVEGSIAPDRFIPVAERTGMIGPLGEWVMQEACRQAQGWREAGLPE
VTVAVNVSPRQFHLTDLAGCAALALADSGLPSTLLELELTEGALAERPEEARQVLLRLRGLGLRLAIDDFGTGYSSLAHL
KRFPIDVLKIDKGFIRDLPQSADDMAICAAIIAMGHSLGLAVLAEGVETPEQLAFLRSRGCDRYQGYLCRRPVPSAEFAA
LLAQQAAGVDAPSPAQP

Sequences:

>Translated_657_residues
MHEEEGGAPRNAPGRTAGWRVPAALLLYAAAGLAWVAGAEALLPAGSVLRGALQAAFVLAPAGCGVWALRRWRARGREIA
VLARGALQADERQRLAATVVDNAAEGMVVTDAESRILSVNAAFTRLMGYGEAELLGRTPRLFKSGRHGRAFYEAMWEELG
RTGHWQGEIWNRRKNGEVFPERMSLSSVRNARGEVTHYVCLFTDISQEHEQRRRLEVMAHTDPLTGLPNRTFFAQQLEEA
MADARARGEPLAVLLVNLDRFKDVNDSYGHAVGDQVLRHIAARVQEALRPGDLAGRLAGDEIGVIARRVDGAQGAVAAAR
ALLGALAEPWRSPDGFEVVASASVGICLFPDHGDTADALLQGAHAAVYGAREHGQGAWHFFDESLTQAARERLALEARLR
SALAQGHLQLHYQPQVDIASGRIVGAEALVRWIDPVEGSIAPDRFIPVAERTGMIGPLGEWVMQEACRQAQGWREAGLPE
VTVAVNVSPRQFHLTDLAGCAALALADSGLPSTLLELELTEGALAERPEEARQVLLRLRGLGLRLAIDDFGTGYSSLAHL
KRFPIDVLKIDKGFIRDLPQSADDMAICAAIIAMGHSLGLAVLAEGVETPEQLAFLRSRGCDRYQGYLCRRPVPSAEFAA
LLAQQAAGVDAPSPAQP
>Mature_657_residues
MHEEEGGAPRNAPGRTAGWRVPAALLLYAAAGLAWVAGAEALLPAGSVLRGALQAAFVLAPAGCGVWALRRWRARGREIA
VLARGALQADERQRLAATVVDNAAEGMVVTDAESRILSVNAAFTRLMGYGEAELLGRTPRLFKSGRHGRAFYEAMWEELG
RTGHWQGEIWNRRKNGEVFPERMSLSSVRNARGEVTHYVCLFTDISQEHEQRRRLEVMAHTDPLTGLPNRTFFAQQLEEA
MADARARGEPLAVLLVNLDRFKDVNDSYGHAVGDQVLRHIAARVQEALRPGDLAGRLAGDEIGVIARRVDGAQGAVAAAR
ALLGALAEPWRSPDGFEVVASASVGICLFPDHGDTADALLQGAHAAVYGAREHGQGAWHFFDESLTQAARERLALEARLR
SALAQGHLQLHYQPQVDIASGRIVGAEALVRWIDPVEGSIAPDRFIPVAERTGMIGPLGEWVMQEACRQAQGWREAGLPE
VTVAVNVSPRQFHLTDLAGCAALALADSGLPSTLLELELTEGALAERPEEARQVLLRLRGLGLRLAIDDFGTGYSSLAHL
KRFPIDVLKIDKGFIRDLPQSADDMAICAAIIAMGHSLGLAVLAEGVETPEQLAFLRSRGCDRYQGYLCRRPVPSAEFAA
LLAQQAAGVDAPSPAQP

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=555, Percent_Identity=35.1351351351351, Blast_Score=312, Evalue=5e-86,
Organism=Escherichia coli, GI87081921, Length=454, Percent_Identity=34.3612334801762, Blast_Score=268, Evalue=7e-73,
Organism=Escherichia coli, GI226510982, Length=422, Percent_Identity=33.175355450237, Blast_Score=205, Evalue=1e-53,
Organism=Escherichia coli, GI1790496, Length=255, Percent_Identity=34.9019607843137, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788502, Length=248, Percent_Identity=35.0806451612903, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI87081980, Length=261, Percent_Identity=36.7816091954023, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787055, Length=398, Percent_Identity=26.8844221105528, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=33.195020746888, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788849, Length=429, Percent_Identity=27.972027972028, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=33.6032388663968, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI87082096, Length=455, Percent_Identity=25.9340659340659, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788381, Length=548, Percent_Identity=24.6350364963504, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=30.9090909090909, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693134, Length=185, Percent_Identity=29.1891891891892, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=28.8770053475936, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789650, Length=438, Percent_Identity=22.1461187214612, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788085, Length=160, Percent_Identity=30.625, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=183, Percent_Identity=28.4153005464481, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=29.7752808988764, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787410, Length=235, Percent_Identity=29.3617021276596, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=151, Percent_Identity=32.4503311258278, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87082007, Length=173, Percent_Identity=30.0578034682081, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787816, Length=172, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 70878; Mature: 70878

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEEEGGAPRNAPGRTAGWRVPAALLLYAAAGLAWVAGAEALLPAGSVLRGALQAAFVLA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCC
PAGCGVWALRRWRARGREIAVLARGALQADERQRLAATVVDNAAEGMVVTDAESRILSVN
CCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHH
AAFTRLMGYGEAELLGRTPRLFKSGRHGRAFYEAMWEELGRTGHWQGEIWNRRKNGEVFP
HHHHHHHCCCCHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCH
ERMSLSSVRNARGEVTHYVCLFTDISQEHEQRRRLEVMAHTDPLTGLPNRTFFAQQLEEA
HHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
MADARARGEPLAVLLVNLDRFKDVNDSYGHAVGDQVLRHIAARVQEALRPGDLAGRLAGD
HHHHHHCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCC
EIGVIARRVDGAQGAVAAARALLGALAEPWRSPDGFEVVASASVGICLFPDHGDTADALL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCHHHHHH
QGAHAAVYGAREHGQGAWHFFDESLTQAARERLALEARLRSALAQGHLQLHYQPQVDIAS
HCCHHHEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEECC
GRIVGAEALVRWIDPVEGSIAPDRFIPVAERTGMIGPLGEWVMQEACRQAQGWREAGLPE
CCEECHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCCCE
VTVAVNVSPRQFHLTDLAGCAALALADSGLPSTLLELELTEGALAERPEEARQVLLRLRG
EEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCHHEEEEECCCHHHCCCHHHHHHHHHHHC
LGLRLAIDDFGTGYSSLAHLKRFPIDVLKIDKGFIRDLPQSADDMAICAAIIAMGHSLGL
CCEEEEECCCCCCHHHHHHHHHCCCHHEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AVLAEGVETPEQLAFLRSRGCDRYQGYLCRRPVPSAEFAALLAQQAAGVDAPSPAQP
HHHHHCCCCHHHHHHHHHCCCCHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHEEEGGAPRNAPGRTAGWRVPAALLLYAAAGLAWVAGAEALLPAGSVLRGALQAAFVLA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCC
PAGCGVWALRRWRARGREIAVLARGALQADERQRLAATVVDNAAEGMVVTDAESRILSVN
CCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHH
AAFTRLMGYGEAELLGRTPRLFKSGRHGRAFYEAMWEELGRTGHWQGEIWNRRKNGEVFP
HHHHHHHCCCCHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCH
ERMSLSSVRNARGEVTHYVCLFTDISQEHEQRRRLEVMAHTDPLTGLPNRTFFAQQLEEA
HHHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
MADARARGEPLAVLLVNLDRFKDVNDSYGHAVGDQVLRHIAARVQEALRPGDLAGRLAGD
HHHHHHCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCC
EIGVIARRVDGAQGAVAAARALLGALAEPWRSPDGFEVVASASVGICLFPDHGDTADALL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCHHHHHH
QGAHAAVYGAREHGQGAWHFFDESLTQAARERLALEARLRSALAQGHLQLHYQPQVDIAS
HCCHHHEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEECC
GRIVGAEALVRWIDPVEGSIAPDRFIPVAERTGMIGPLGEWVMQEACRQAQGWREAGLPE
CCEECHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCHHHCCCCE
VTVAVNVSPRQFHLTDLAGCAALALADSGLPSTLLELELTEGALAERPEEARQVLLRLRG
EEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCHHEEEEECCCHHHCCCHHHHHHHHHHHC
LGLRLAIDDFGTGYSSLAHLKRFPIDVLKIDKGFIRDLPQSADDMAICAAIIAMGHSLGL
CCEEEEECCCCCCHHHHHHHHHCCCHHEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AVLAEGVETPEQLAFLRSRGCDRYQGYLCRRPVPSAEFAALLAQQAAGVDAPSPAQP
HHHHHCCCCHHHHHHHHHCCCCHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]