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The map label for this gene is glpD [H]

Identifier: 120609310

GI number: 120609310

Start: 667817

End: 669439

Strand: Direct

Name: glpD [H]

Synonym: Aave_0610

Alternate gene names: 120609310

Gene position: 667817-669439 (Clockwise)

Preceding gene: 120609309

Following gene: 120609311

Centisome position: 12.48

GC content: 72.46

Gene sequence:

>1623_bases
TTGGCCCGGTTGAATGGACAATTCATCGCCATGACTCTCCCGAACACGCCCCTGCCCACCGACCGCGCCCGACTGCTGGC
GCAGCTTGCCGAACCCCGCCAGTACGACCTGGCGGTCATCGGGGGCGGGGCGACGGGGCTGGGCGCGGCGCTCGACGCCG
CGGCGCGCGGCTTCAGCGTCGTCCTGGTCGAGTCCCACGATTTCGCGAAAGGCACGTCCTCGCGCGCCACCAAGCTCGTG
CACGGCGGTGTCCGCTACCTCGCGCAGGGCAACATCTCGCTCGTGCGCGAGGCACTGCACGAGCGCACCACGCTGCTCGG
CAATGCGCCGCACCTGGCGCAGCCGCTGCCCTTCGTGATGCCGTCCTACCGTTTCTGGGAGACGCCCTTCTACGGCATGG
GCCTCAAGGCCTACGACCTGCTGGCGGGCCGCGCCGGCCTGGGTACCACCGAATTCCTGGGCCGGGAGGGCACGCTGCGC
CTTCTGCCCACCGTGCGCCGCGATGGCCTGCAGGGCGGCGTCAAGTATTGGGACGGCCAGTTCGACGACGCACGGCTCGC
CCTGGCGCTCGCGCGCACCGCGGCGCTGCGCGGCGCGCTGCTCGTCAACTACTGCCCGGCGCGCGAGCTCATCCACGAGA
ACGGCAAGGTCGCGGGCCTGCGCTGCGAGGACGCCGAAACCGGCACCCCATACACCCTGCGGGCGCGCTGCGTCGTCAAT
GCCACGGGGGTCTGGGTGGACGGCCTGCGCAGCCAGGACGCCGAAGCCCTCGGCCGGCCCGCGCGGCCCATCGTCGCGCC
CAGCCAGGGCGTGCACATCGTGGTGGACCGGGAGTTCCTTCCCTCCGACCACGCGATGATGGTGCCGAAGACGGCAGACG
GCCGCGTCCTCTTCGCCGTGCCCTGGCTCGGCAAGGTCATCCTCGGCACCACCGACAGCCCCCGCCAGGATCTGGAGCGC
GAGCCGCGCCCGTTCAAGGAAGAGGCCGCCTTCATCCTGAGCGAATCGGCGCGCTACCTCACCCGCGCGCCGTCGGCCGC
GGACGTGCGCAGCATCTGGGTGGGCCTGCGCCCGCTGGTGCGCCCGCCCGACGACGAGGGGGGCAACACCAAGAGCATCA
GCCGCGAGCACACCGTGCTGGCGAGCCCGAGCGGCCTGGTCACGGTGACCGGCGGCAAATGGACCACCTACCGCGCCATG
GCGGAGGACGTGTTGCAGAAATGCTTCGATGCCGGCCTGCTGCCGGCCCGTGCCGGCGGGGCGACCCAGCGCCTGCCGGT
GGTGGGCGCGCCGGACGGCCCGGTGCAGCACGGCATGGACGAGGCCCAGGGCCCGCATTCCTACGGCTCGGAGGCGGTCT
TCCTGGACAATGTACCCGGCGCGCAACACTGGCTGGCGCCGGGCCTCTCCGAGGCCATGGTCCGCTTCGCCGCGCGCCAC
GAGTACGCGCGCACCGTCGAGGACATGCTCGCGCGCCGCAGCCGCATGCTCTTCCTCGACGCCGCACAGGCCCTGCGCCT
GGCCCCGCAGGTGGCCGCCATCCTCGCCGAAGAGCTGGGCACCGACCCGGGCCTGGCCGCGTTCGAGGCGCTCGCCGCGC
AGTACCACACGGTTCCTGCGTAA

Upstream 100 bases:

>100_bases
GGGGCCGCTTCCGTTTTTCGGCACTCTCCCGCCTGGCCCGCTCGCGAGGCTGCGCGGGAGATCCGCTTTTGAAGGGGCAT
ATCAGGGTTTACCCTGTGTA

Downstream 100 bases:

>100_bases
CCGATTGACACGCCCTTTCTTTTTTGAAAGAATCGAGGGCTTCGCGTTTCTCTACGCGGATTTCTGCCCAGCGGGAAGCG
GTGCAAATGGTTTGCACCGC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MARLNGQFIAMTLPNTPLPTDRARLLAQLAEPRQYDLAVIGGGATGLGAALDAAARGFSVVLVESHDFAKGTSSRATKLV
HGGVRYLAQGNISLVREALHERTTLLGNAPHLAQPLPFVMPSYRFWETPFYGMGLKAYDLLAGRAGLGTTEFLGREGTLR
LLPTVRRDGLQGGVKYWDGQFDDARLALALARTAALRGALLVNYCPARELIHENGKVAGLRCEDAETGTPYTLRARCVVN
ATGVWVDGLRSQDAEALGRPARPIVAPSQGVHIVVDREFLPSDHAMMVPKTADGRVLFAVPWLGKVILGTTDSPRQDLER
EPRPFKEEAAFILSESARYLTRAPSAADVRSIWVGLRPLVRPPDDEGGNTKSISREHTVLASPSGLVTVTGGKWTTYRAM
AEDVLQKCFDAGLLPARAGGATQRLPVVGAPDGPVQHGMDEAQGPHSYGSEAVFLDNVPGAQHWLAPGLSEAMVRFAARH
EYARTVEDMLARRSRMLFLDAAQALRLAPQVAAILAEELGTDPGLAAFEALAAQYHTVPA

Sequences:

>Translated_540_residues
MARLNGQFIAMTLPNTPLPTDRARLLAQLAEPRQYDLAVIGGGATGLGAALDAAARGFSVVLVESHDFAKGTSSRATKLV
HGGVRYLAQGNISLVREALHERTTLLGNAPHLAQPLPFVMPSYRFWETPFYGMGLKAYDLLAGRAGLGTTEFLGREGTLR
LLPTVRRDGLQGGVKYWDGQFDDARLALALARTAALRGALLVNYCPARELIHENGKVAGLRCEDAETGTPYTLRARCVVN
ATGVWVDGLRSQDAEALGRPARPIVAPSQGVHIVVDREFLPSDHAMMVPKTADGRVLFAVPWLGKVILGTTDSPRQDLER
EPRPFKEEAAFILSESARYLTRAPSAADVRSIWVGLRPLVRPPDDEGGNTKSISREHTVLASPSGLVTVTGGKWTTYRAM
AEDVLQKCFDAGLLPARAGGATQRLPVVGAPDGPVQHGMDEAQGPHSYGSEAVFLDNVPGAQHWLAPGLSEAMVRFAARH
EYARTVEDMLARRSRMLFLDAAQALRLAPQVAAILAEELGTDPGLAAFEALAAQYHTVPA
>Mature_539_residues
ARLNGQFIAMTLPNTPLPTDRARLLAQLAEPRQYDLAVIGGGATGLGAALDAAARGFSVVLVESHDFAKGTSSRATKLVH
GGVRYLAQGNISLVREALHERTTLLGNAPHLAQPLPFVMPSYRFWETPFYGMGLKAYDLLAGRAGLGTTEFLGREGTLRL
LPTVRRDGLQGGVKYWDGQFDDARLALALARTAALRGALLVNYCPARELIHENGKVAGLRCEDAETGTPYTLRARCVVNA
TGVWVDGLRSQDAEALGRPARPIVAPSQGVHIVVDREFLPSDHAMMVPKTADGRVLFAVPWLGKVILGTTDSPRQDLERE
PRPFKEEAAFILSESARYLTRAPSAADVRSIWVGLRPLVRPPDDEGGNTKSISREHTVLASPSGLVTVTGGKWTTYRAMA
EDVLQKCFDAGLLPARAGGATQRLPVVGAPDGPVQHGMDEAQGPHSYGSEAVFLDNVPGAQHWLAPGLSEAMVRFAARHE
YARTVEDMLARRSRMLFLDAAQALRLAPQVAAILAEELGTDPGLAAFEALAAQYHTVPA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=547, Percent_Identity=39.6709323583181, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI285002231, Length=547, Percent_Identity=39.6709323583181, Blast_Score=362, Evalue=1e-100,
Organism=Escherichia coli, GI2367226, Length=494, Percent_Identity=29.9595141700405, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1788574, Length=361, Percent_Identity=30.4709141274238, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17509253, Length=538, Percent_Identity=40.5204460966543, Blast_Score=343, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI115534726, Length=542, Percent_Identity=36.1623616236162, Blast_Score=318, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6322036, Length=579, Percent_Identity=34.7150259067358, Blast_Score=318, Evalue=2e-87,
Organism=Drosophila melanogaster, GI161077125, Length=535, Percent_Identity=39.6261682242991, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24653942, Length=535, Percent_Identity=39.6261682242991, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24653944, Length=535, Percent_Identity=39.6261682242991, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI20130025, Length=535, Percent_Identity=39.6261682242991, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24586295, Length=537, Percent_Identity=34.4506517690875, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI19921278, Length=515, Percent_Identity=30.4854368932039, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI45550977, Length=398, Percent_Identity=29.1457286432161, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 58060; Mature: 57929

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLNGQFIAMTLPNTPLPTDRARLLAQLAEPRQYDLAVIGGGATGLGAALDAAARGFSV
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCEEE
VLVESHDFAKGTSSRATKLVHGGVRYLAQGNISLVREALHERTTLLGNAPHLAQPLPFVM
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHCCCCCHHC
PSYRFWETPFYGMGLKAYDLLAGRAGLGTTEFLGREGTLRLLPTVRRDGLQGGVKYWDGQ
CCCHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCCCEEECCHHHHCCCCCCCHHCCCC
FDDARLALALARTAALRGALLVNYCPARELIHENGKVAGLRCEDAETGTPYTLRARCVVN
CCCHHHHHHHHHHHHHHCHHEEEECCHHHHHHCCCCEEEEEECCCCCCCCEEEEEEEEEE
ATGVWVDGLRSQDAEALGRPARPIVAPSQGVHIVVDREFLPSDHAMMVPKTADGRVLFAV
ECCCEECCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEE
PWLGKVILGTTDSPRQDLEREPRPFKEEAAFILSESARYLTRAPSAADVRSIWVGLRPLV
CCCCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
RPPDDEGGNTKSISREHTVLASPSGLVTVTGGKWTTYRAMAEDVLQKCFDAGLLPARAGG
CCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ATQRLPVVGAPDGPVQHGMDEAQGPHSYGSEAVFLDNVPGAQHWLAPGLSEAMVRFAARH
CCCCCEEEECCCCHHHCCCHHCCCCCCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHH
EYARTVEDMLARRSRMLFLDAAQALRLAPQVAAILAEELGTDPGLAAFEALAAQYHTVPA
HHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARLNGQFIAMTLPNTPLPTDRARLLAQLAEPRQYDLAVIGGGATGLGAALDAAARGFSV
CCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCEEE
VLVESHDFAKGTSSRATKLVHGGVRYLAQGNISLVREALHERTTLLGNAPHLAQPLPFVM
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHCCCCCHHC
PSYRFWETPFYGMGLKAYDLLAGRAGLGTTEFLGREGTLRLLPTVRRDGLQGGVKYWDGQ
CCCHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCCCEEECCHHHHCCCCCCCHHCCCC
FDDARLALALARTAALRGALLVNYCPARELIHENGKVAGLRCEDAETGTPYTLRARCVVN
CCCHHHHHHHHHHHHHHCHHEEEECCHHHHHHCCCCEEEEEECCCCCCCCEEEEEEEEEE
ATGVWVDGLRSQDAEALGRPARPIVAPSQGVHIVVDREFLPSDHAMMVPKTADGRVLFAV
ECCCEECCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEE
PWLGKVILGTTDSPRQDLEREPRPFKEEAAFILSESARYLTRAPSAADVRSIWVGLRPLV
CCCCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
RPPDDEGGNTKSISREHTVLASPSGLVTVTGGKWTTYRAMAEDVLQKCFDAGLLPARAGG
CCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ATQRLPVVGAPDGPVQHGMDEAQGPHSYGSEAVFLDNVPGAQHWLAPGLSEAMVRFAARH
CCCCCEEEECCCCHHHCCCHHCCCCCCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHH
EYARTVEDMLARRSRMLFLDAAQALRLAPQVAAILAEELGTDPGLAAFEALAAQYHTVPA
HHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]