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The map label for this gene is trpG [H]

Identifier: 120609283

GI number: 120609283

Start: 636404

End: 636976

Strand: Direct

Name: trpG [H]

Synonym: Aave_0583

Alternate gene names: 120609283

Gene position: 636404-636976 (Clockwise)

Preceding gene: 120609281

Following gene: 120609284

Centisome position: 11.89

GC content: 65.62

Gene sequence:

>573_bases
ATGACAGTTCTGATGGTCGACAACTACGACAGCTTCACCTACAACATCGTCCAGTACTTCGGAGAACTGGGCGCCCAGGT
GGAAGTGCACCGCAACGACGAGATCACCGTGGAGGAGATCGCGGCCCGCAATCCGCGCCACCTCGTCATCTCGCCCGGCC
CGTGCTCGCCCGCGGAGGCCGGCGTCTCCGTGGAGGCCATCCGCCACTTCGCGGGCAAGCTGCCCATCCTGGGCGTGTGC
CTGGGCCACCAGTCCATCGGGGCGGCCTTCGGCGGACGCATCATCCGGGCCCGCGAGCTGATGCACGGCAAGACCAGCAC
CATCACCACCACCGGCCAGGGCGTGTTCGCCGGGCTGCCGGAGCAGTTCACCGTGAACCGCTACCACTCGCTGTCCATCG
AGCGCGAGTCCTGCCCCGAGGTGCTGGAGGTCACGGCCTGGACAGACGATGGCGAGATCATGGGCGTGCGCCACAAGGAA
CTGCCCATCGAAGGCGTGCAGTTCCACCCCGAGAGCATCCTCACCGAGCATGGGCATGCCATGCTGAAGAACTTCCTCTC
GATGAAGGCGTGA

Upstream 100 bases:

>100_bases
ACAGAAGGCGCCATTGGAATCCACTGCAAATGTGTATATCAGCGTGTATATGCAGCCTGTGGCCTAAAAAAATTAGCAAT
TAAATCAAGGACTTAAGTCT

Downstream 100 bases:

>100_bases
CCGCCATGGACGCCTCCCCGGTCTCCACCGGTCCCGCGCCGGCCGCCGCGGGTCGCCGGTAAGGATTCGCCGTGCCGGAT
TTCCACCATCTGCTGCTGTT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MTVLMVDNYDSFTYNIVQYFGELGAQVEVHRNDEITVEEIAARNPRHLVISPGPCSPAEAGVSVEAIRHFAGKLPILGVC
LGHQSIGAAFGGRIIRARELMHGKTSTITTTGQGVFAGLPEQFTVNRYHSLSIERESCPEVLEVTAWTDDGEIMGVRHKE
LPIEGVQFHPESILTEHGHAMLKNFLSMKA

Sequences:

>Translated_190_residues
MTVLMVDNYDSFTYNIVQYFGELGAQVEVHRNDEITVEEIAARNPRHLVISPGPCSPAEAGVSVEAIRHFAGKLPILGVC
LGHQSIGAAFGGRIIRARELMHGKTSTITTTGQGVFAGLPEQFTVNRYHSLSIERESCPEVLEVTAWTDDGEIMGVRHKE
LPIEGVQFHPESILTEHGHAMLKNFLSMKA
>Mature_189_residues
TVLMVDNYDSFTYNIVQYFGELGAQVEVHRNDEITVEEIAARNPRHLVISPGPCSPAEAGVSVEAIRHFAGKLPILGVCL
GHQSIGAAFGGRIIRARELMHGKTSTITTTGQGVFAGLPEQFTVNRYHSLSIERESCPEVLEVTAWTDDGEIMGVRHKEL
PIEGVQFHPESILTEHGHAMLKNFLSMKA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=184, Percent_Identity=60.3260869565217, Blast_Score=252, Evalue=8e-69,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=42.5531914893617, Blast_Score=144, Evalue=3e-36,
Organism=Escherichia coli, GI1786215, Length=151, Percent_Identity=25.8278145695364, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=24.7368421052632, Blast_Score=60, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=52.4064171122995, Blast_Score=211, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=29.7169811320755, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281365319, Length=142, Percent_Identity=35.2112676056338, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20880; Mature: 20749

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLMVDNYDSFTYNIVQYFGELGAQVEVHRNDEITVEEIAARNPRHLVISPGPCSPAEA
CEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCEEHHHHHCCCCCEEEEECCCCCHHHC
GVSVEAIRHFAGKLPILGVCLGHQSIGAAFGGRIIRARELMHGKTSTITTTGQGVFAGLP
CCCHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHHHHHHCCCCCEEEECCCCEEECCC
EQFTVNRYHSLSIERESCPEVLEVTAWTDDGEIMGVRHKELPIEGVQFHPESILTEHGHA
CCEECCCEEEEEECHHCCCCCEEEEEECCCCCEEEEECCCCCCCCEEECHHHHHHHCCHH
MLKNFLSMKA
HHHHHHHCCC
>Mature Secondary Structure 
TVLMVDNYDSFTYNIVQYFGELGAQVEVHRNDEITVEEIAARNPRHLVISPGPCSPAEA
EEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCEEHHHHHCCCCCEEEEECCCCCHHHC
GVSVEAIRHFAGKLPILGVCLGHQSIGAAFGGRIIRARELMHGKTSTITTTGQGVFAGLP
CCCHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHHHHHHCCCCCEEEECCCCEEECCC
EQFTVNRYHSLSIERESCPEVLEVTAWTDDGEIMGVRHKELPIEGVQFHPESILTEHGHA
CCEECCCEEEEEECHHCCCCCEEEEEECCCCCEEEEECCCCCCCCEEECHHHHHHHCCHH
MLKNFLSMKA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]