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The map label for this gene is argS

Identifier: 120609117

GI number: 120609117

Start: 446167

End: 447876

Strand: Direct

Name: argS

Synonym: Aave_0414

Alternate gene names: 120609117

Gene position: 446167-447876 (Clockwise)

Preceding gene: 120609115

Following gene: 120609118

Centisome position: 8.34

GC content: 66.78

Gene sequence:

>1710_bases
ATGCTCTCCGTCAAACAGGAATTGCTCGCGGCGCTGGCCGGCGAGCTGGAAAAACTCTCGCCCGGCTCCGCCGGGCGCGC
CGCTTTCGAATCCCCCAAGGTGGCCGCGCACGGTGATTTCGCATGCACCGCCGCCATGCAGCTGGCCAAGCCGCTCAAGC
TCAATCCGCGCGCACTGGGCGAACAGCTCAAGGCCGCGCTGGAGGCCACGCCGGCCTTCGCGCGCTGGGTCGATGCCATC
GAGATCGCCGGCCCCGGCTTCCTGAACATCCGCCTCAAAGCCGCCGCCAAGCAGGAGATCGTGCGCGAAGTGCTGTCCGC
CGGCGACCGGTTCGGCTACCAGAAGGACAACGGCCAGCGCGTGCTGGTGGAGTTCGTCTCCGCCAATCCCACGGGGCCGC
TGCACGTGGGCCACGGCCGCCAGGCCGCCCTGGGCGATGCGATCTGCAACCTCTTCAGCACCCAGGGCTGGAGCGTGCAC
CGCGAGTTCTACTACAACGACGCGGGCGTGCAGATCGACACGCTCACCAAGAGCACGCAGCTGCGCGCCAGGGGCTTCAA
GCCCGGCGACGAGTGCTGGCCCACCGATCCGGAGAACCCGGCCTCCAAGACGTTCTACAACGGCGACTACATCCAGGACA
TCGCGAACGACTTCCTGGCGAAGAAGACCGTGAAGGCGGACGACCGCGAATTCACCGCCAACGGCGACGTCGAGGATTAC
GACAACATCCGCCAGTTCGCCGTGGCCTACCTGCGCAACGAGCAGGACAAGGACCTGCAGGCGTTCAACCTGCATTTCGA
CCAGTACTACCTGGAGTCCAGCCTCTACACCTCGGGCCGCGTCGAGGCCACCGTGAACCGCCTGGTCGAGAAGGGCCACA
CCTACGAGCAGGACGGCGCGCTGTGGCTCAAGTCCACCGACTACGGGGACGACAAGGACCGCGTGATGCGCAAGAAGGAC
GGCACGTACACGTACTTCGTGCCCGACGTGGCCTACCACATCGCCAAGTGGGAACGCGGCTTCGCCAAGGTCGTGAACAT
CCAGGGCACGGACCACCACGGCACCATCGCGCGCGTGCGCGCCGGCCTGCAGGCGGCCGACGTGGGCATTCCGCAGGGCT
ACCCCGACTACGTGCTGCATACCATGGTGCGCGTGGTCAAGGGCGGAAAAGAGGTGAAGATCGGCAAGCGCGCGGGCAGC
TACGTGACGCTGCGCGACCTGATCGAATGGACCAGCAAGGACGCAGTGCGCTTCTTCCTGCTCTCGCGCAAGCCCGACAC
GGAGTACACCTTCGACGTCGATCTGGCGGTGGCGCAGAACAACGACAACCCGGTCTATTACGTGCAGTACGCGCATGCGC
GCATCCAGTCGGTGCTGCGGGCTTGGGCAGAGGCCGGCGGCGGCGATGTCGCTTCGCTCAAGGACGTGGATCTGTCGGCC
CTGGAGGGCCCGCAGGCCCAGGCCCTCATGCTGCAGCTCGCCAAGTACCCGGAGATGCTGACGGCCGCCGCCGAGGGCGA
GGCCCCGCACGATGTGACCTTCTACCTGCGCGACCTGGCCGCCAGCTACCACAGCTATTACGACGCCGAGCGCATCCTCG
TGGACGACGAGGCCGTCAAGCGCGCCCGCCTCGCGCTGGTCGCCGCCACGGCGCAGGTATTGCACAATGGCCTGAAGGTG
CTGGGCGTGGACGCGCCCGCGAGAATGTGA

Upstream 100 bases:

>100_bases
AGGGGTTGGCGCCCCGGCCTCCGTTGCCGAAGGACGGGACTGTCCAGCTTAACGCCGCTGGTCGCCGTGCGGATGACGGG
CCGGCCCGTAGAATCCGCGC

Downstream 100 bases:

>100_bases
ACCATATGACCAAGAAGCAGCAACGCGGCGGCTCGGCCGTCGGCTTCATCCTGGGGATCGTCGTGGGGCTGGGCGTCGCG
CTCGCCGTGGCGGTGTACGT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MLSVKQELLAALAGELEKLSPGSAGRAAFESPKVAAHGDFACTAAMQLAKPLKLNPRALGEQLKAALEATPAFARWVDAI
EIAGPGFLNIRLKAAAKQEIVREVLSAGDRFGYQKDNGQRVLVEFVSANPTGPLHVGHGRQAALGDAICNLFSTQGWSVH
REFYYNDAGVQIDTLTKSTQLRARGFKPGDECWPTDPENPASKTFYNGDYIQDIANDFLAKKTVKADDREFTANGDVEDY
DNIRQFAVAYLRNEQDKDLQAFNLHFDQYYLESSLYTSGRVEATVNRLVEKGHTYEQDGALWLKSTDYGDDKDRVMRKKD
GTYTYFVPDVAYHIAKWERGFAKVVNIQGTDHHGTIARVRAGLQAADVGIPQGYPDYVLHTMVRVVKGGKEVKIGKRAGS
YVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARIQSVLRAWAEAGGGDVASLKDVDLSA
LEGPQAQALMLQLAKYPEMLTAAAEGEAPHDVTFYLRDLAASYHSYYDAERILVDDEAVKRARLALVAATAQVLHNGLKV
LGVDAPARM

Sequences:

>Translated_569_residues
MLSVKQELLAALAGELEKLSPGSAGRAAFESPKVAAHGDFACTAAMQLAKPLKLNPRALGEQLKAALEATPAFARWVDAI
EIAGPGFLNIRLKAAAKQEIVREVLSAGDRFGYQKDNGQRVLVEFVSANPTGPLHVGHGRQAALGDAICNLFSTQGWSVH
REFYYNDAGVQIDTLTKSTQLRARGFKPGDECWPTDPENPASKTFYNGDYIQDIANDFLAKKTVKADDREFTANGDVEDY
DNIRQFAVAYLRNEQDKDLQAFNLHFDQYYLESSLYTSGRVEATVNRLVEKGHTYEQDGALWLKSTDYGDDKDRVMRKKD
GTYTYFVPDVAYHIAKWERGFAKVVNIQGTDHHGTIARVRAGLQAADVGIPQGYPDYVLHTMVRVVKGGKEVKIGKRAGS
YVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARIQSVLRAWAEAGGGDVASLKDVDLSA
LEGPQAQALMLQLAKYPEMLTAAAEGEAPHDVTFYLRDLAASYHSYYDAERILVDDEAVKRARLALVAATAQVLHNGLKV
LGVDAPARM
>Mature_569_residues
MLSVKQELLAALAGELEKLSPGSAGRAAFESPKVAAHGDFACTAAMQLAKPLKLNPRALGEQLKAALEATPAFARWVDAI
EIAGPGFLNIRLKAAAKQEIVREVLSAGDRFGYQKDNGQRVLVEFVSANPTGPLHVGHGRQAALGDAICNLFSTQGWSVH
REFYYNDAGVQIDTLTKSTQLRARGFKPGDECWPTDPENPASKTFYNGDYIQDIANDFLAKKTVKADDREFTANGDVEDY
DNIRQFAVAYLRNEQDKDLQAFNLHFDQYYLESSLYTSGRVEATVNRLVEKGHTYEQDGALWLKSTDYGDDKDRVMRKKD
GTYTYFVPDVAYHIAKWERGFAKVVNIQGTDHHGTIARVRAGLQAADVGIPQGYPDYVLHTMVRVVKGGKEVKIGKRAGS
YVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARIQSVLRAWAEAGGGDVASLKDVDLSA
LEGPQAQALMLQLAKYPEMLTAAAEGEAPHDVTFYLRDLAASYHSYYDAERILVDDEAVKRARLALVAATAQVLHNGLKV
LGVDAPARM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=635, Percent_Identity=22.992125984252, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1788184, Length=606, Percent_Identity=28.0528052805281, Blast_Score=135, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71985061, Length=574, Percent_Identity=23.8675958188153, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=538, Percent_Identity=23.4200743494424, Blast_Score=86, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320548, Length=552, Percent_Identity=25.9057971014493, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321883, Length=512, Percent_Identity=26.3671875, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ACIAC (A1TJ83)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968795.1
- ProteinModelPortal:   A1TJ83
- STRING:   A1TJ83
- GeneID:   4668362
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0414
- NMPDR:   fig|397945.5.peg.369
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   AAVE397945:AAVE_0414-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62896; Mature: 62896

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVKQELLAALAGELEKLSPGSAGRAAFESPKVAAHGDFACTAAMQLAKPLKLNPRALG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
EQLKAALEATPAFARWVDAIEIAGPGFLNIRLKAAAKQEIVREVLSAGDRFGYQKDNGQR
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCHHCCCCCCCCCE
VLVEFVSANPTGPLHVGHGRQAALGDAICNLFSTQGWSVHREFYYNDAGVQIDTLTKSTQ
EEEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCHH
LRARGFKPGDECWPTDPENPASKTFYNGDYIQDIANDFLAKKTVKADDREFTANGDVEDY
HHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHH
DNIRQFAVAYLRNEQDKDLQAFNLHFDQYYLESSLYTSGRVEATVNRLVEKGHTYEQDGA
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCE
LWLKSTDYGDDKDRVMRKKDGTYTYFVPDVAYHIAKWERGFAKVVNIQGTDHHGTIARVR
EEEEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
AGLQAADVGIPQGYPDYVLHTMVRVVKGGKEVKIGKRAGSYVTLRDLIEWTSKDAVRFFL
HCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCCEEEEE
LSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARIQSVLRAWAEAGGGDVASLKDVDLSA
EECCCCCCEEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LEGPQAQALMLQLAKYPEMLTAAAEGEAPHDVTFYLRDLAASYHSYYDAERILVDDEAVK
CCCCHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHH
RARLALVAATAQVLHNGLKVLGVDAPARM
HHHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MLSVKQELLAALAGELEKLSPGSAGRAAFESPKVAAHGDFACTAAMQLAKPLKLNPRALG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
EQLKAALEATPAFARWVDAIEIAGPGFLNIRLKAAAKQEIVREVLSAGDRFGYQKDNGQR
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCHHCCCCCCCCCE
VLVEFVSANPTGPLHVGHGRQAALGDAICNLFSTQGWSVHREFYYNDAGVQIDTLTKSTQ
EEEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCHH
LRARGFKPGDECWPTDPENPASKTFYNGDYIQDIANDFLAKKTVKADDREFTANGDVEDY
HHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHH
DNIRQFAVAYLRNEQDKDLQAFNLHFDQYYLESSLYTSGRVEATVNRLVEKGHTYEQDGA
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCE
LWLKSTDYGDDKDRVMRKKDGTYTYFVPDVAYHIAKWERGFAKVVNIQGTDHHGTIARVR
EEEEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
AGLQAADVGIPQGYPDYVLHTMVRVVKGGKEVKIGKRAGSYVTLRDLIEWTSKDAVRFFL
HCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCCCEEEEE
LSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARIQSVLRAWAEAGGGDVASLKDVDLSA
EECCCCCCEEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
LEGPQAQALMLQLAKYPEMLTAAAEGEAPHDVTFYLRDLAASYHSYYDAERILVDDEAVK
CCCCHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHH
RARLALVAATAQVLHNGLKVLGVDAPARM
HHHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA