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The map label for this gene is atpD

Identifier: 120609075

GI number: 120609075

Start: 397486

End: 398916

Strand: Direct

Name: atpD

Synonym: Aave_0372

Alternate gene names: 120609075

Gene position: 397486-398916 (Clockwise)

Preceding gene: 120609074

Following gene: 120609076

Centisome position: 7.43

GC content: 65.13

Gene sequence:

>1431_bases
ATGGCTCAAGAGAACACCCAAGTGAACGCTGGCGTTCAGGGCAAGATCGTTCAATGTATCGGCGCCGTGGTGGACGTCGA
GTTCCCGCGCGACCAGATGCCCAAGGTGTATGACGCGCTCAAGCTCGAAGGCTCCCCCCTGACGCTGGAAGTGCAGCAGC
AGCTCGGCGACGGCGTGGTGCGTACCATCGCCCTGGGTTCGTCCGACGGCCTGCGCCGTGGCCTGATGGTGTCCAACACC
GGCAACCCGATCACCGTGCCCGTGGGCAAGGCGACGCTGGGCCGCATCATGGACGTGCTGGGTTCGCCCATCGACGAGCG
CGGCCCTGTCAGCCAGGAACTGACGGCCTCCATCCACCGCAAGGCCCCTGCGTACGACGAACTGTCGCCGTCGCAGGAGC
TGCTGGAAACCGGCATCAAGGTGATCGACCTGGTGTGCCCGTTCGCCAAGGGCGGCAAGGTGGGCCTGTTCGGTGGCGCC
GGCGTGGGCAAGACCGTGAACATGATGGAGCTCATCAACAACATCGCCAAGGCCCACAGCGGTCTGTCGGTGTTCGCCGG
TGTGGGCGAGCGTACCCGTGAAGGCAACGACTTCTATCACGAAATGGCCGATTCCGGCGTCGTGAACCTCGAGAAGCTCG
AAGACTCCAAGGTCGCCATGGTCTATGGCCAGATGAACGAGCCCCCGGGCAACCGCCTGCGCGTGGCCCTGACCGGCCTG
ACGATCGCCGAATCGTTCCGCGACGAAGGCCGCGACGTGCTGTTCTTCGTGGACAACATCTACCGTTACACCCTGGCCGG
TACCGAAGTGTCCGCACTGCTGGGCCGCATGCCTTCCGCCGTGGGCTACCAGCCGACGCTGGCCGAGGAAATGGGCCGCC
TGCAGGAGCGCATCACCTCCACCAAGGTCGGCTCGATCACCTCCATCCAGGCCGTGTACGTGCCTGCCGATGACTTGACC
GACCCGTCTCCCGCCACGACCTTCGCCCACCTGGACTCCACCGTGGTGCTGTCGCGCGACATCGCCTCGCTGGGTATCTA
CCCCGCCGTGGATCCGCTGGACTCCACCAGCCGCCAGCTGGACCCGCAAGTGGTCGGTGAAGAGCACTACCAGGTGGCCC
GCGGCGTGCAGGGCACCCTGCAGCGCTACAAGGAACTGCGCGACATCATCGCCATCCTGGGCATGGACGAACTGGCTCCC
GAGGACAAGCTGGCCGTGGCCCGCGCCCGGAAGATCCAGCGTTTCCTGTCGCAGCCGTTCCACGTGGCCGAAGTGTTCAC
GGGCTCGCCCGGCAAGTACGTGCCGCTGGCGGAAACCATTCGCGGCTTCAAGATGATCGTGGCCGGCGAGTGCGATCACC
TGCCGGAGCAGGCGTTCTACATGGTCGGGACGATCGACGAAGCCTTCGAAAAGGCCAAGAAGGTCGCGTAA

Upstream 100 bases:

>100_bases
CAAGCTGGTCTACAACAAGACGCGCCAGGCCGCGATCACGAAGGAACTTTCGGAGATCGTCGCGGGTGCCGCGGCAGTTT
AAATTTTTGGAGCAAATGCA

Downstream 100 bases:

>100_bases
AGCGGCGTAATCGGCCACCTCGCGTCGTTGGCGTGCTCAATGTGCTCGATGCACATTTCCGCGCGCCGCCTAGCGATGCG
GCCGATTCCTTGCTTTCCCC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MAQENTQVNAGVQGKIVQCIGAVVDVEFPRDQMPKVYDALKLEGSPLTLEVQQQLGDGVVRTIALGSSDGLRRGLMVSNT
GNPITVPVGKATLGRIMDVLGSPIDERGPVSQELTASIHRKAPAYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGA
GVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMADSGVVNLEKLEDSKVAMVYGQMNEPPGNRLRVALTGL
TIAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLT
DPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQLDPQVVGEEHYQVARGVQGTLQRYKELRDIIAILGMDELAP
EDKLAVARARKIQRFLSQPFHVAEVFTGSPGKYVPLAETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKVA

Sequences:

>Translated_476_residues
MAQENTQVNAGVQGKIVQCIGAVVDVEFPRDQMPKVYDALKLEGSPLTLEVQQQLGDGVVRTIALGSSDGLRRGLMVSNT
GNPITVPVGKATLGRIMDVLGSPIDERGPVSQELTASIHRKAPAYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGA
GVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMADSGVVNLEKLEDSKVAMVYGQMNEPPGNRLRVALTGL
TIAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLT
DPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQLDPQVVGEEHYQVARGVQGTLQRYKELRDIIAILGMDELAP
EDKLAVARARKIQRFLSQPFHVAEVFTGSPGKYVPLAETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKVA
>Mature_475_residues
AQENTQVNAGVQGKIVQCIGAVVDVEFPRDQMPKVYDALKLEGSPLTLEVQQQLGDGVVRTIALGSSDGLRRGLMVSNTG
NPITVPVGKATLGRIMDVLGSPIDERGPVSQELTASIHRKAPAYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGAG
VGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMADSGVVNLEKLEDSKVAMVYGQMNEPPGNRLRVALTGLT
IAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTD
PSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQLDPQVVGEEHYQVARGVQGTLQRYKELRDIIAILGMDELAPE
DKLAVARARKIQRFLSQPFHVAEVFTGSPGKYVPLAETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKVA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=479, Percent_Identity=69.3110647181628, Blast_Score=656, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=310, Percent_Identity=28.7096774193548, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI50345984, Length=407, Percent_Identity=24.0786240786241, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI4757810, Length=407, Percent_Identity=24.0786240786241, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI19913428, Length=447, Percent_Identity=25.0559284116331, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI19913426, Length=408, Percent_Identity=24.5098039215686, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1790170, Length=464, Percent_Identity=80.6034482758621, Blast_Score=753, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=312, Percent_Identity=31.4102564102564, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1790172, Length=406, Percent_Identity=24.384236453202, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=470, Percent_Identity=68.7234042553192, Blast_Score=650, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=406, Percent_Identity=24.1379310344828, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=406, Percent_Identity=24.1379310344828, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=316, Percent_Identity=28.1645569620253, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17510931, Length=357, Percent_Identity=25.4901960784314, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17570191, Length=430, Percent_Identity=24.4186046511628, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=349, Percent_Identity=23.2091690544413, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=459, Percent_Identity=66.6666666666667, Blast_Score=620, Evalue=1e-178,
Organism=Saccharomyces cerevisiae, GI6319370, Length=427, Percent_Identity=26.463700234192, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319603, Length=436, Percent_Identity=25.6880733944954, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=217, Percent_Identity=25.3456221198157, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24638766, Length=467, Percent_Identity=69.3790149892934, Blast_Score=649, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=472, Percent_Identity=64.6186440677966, Blast_Score=605, Evalue=1e-173,
Organism=Drosophila melanogaster, GI20129479, Length=319, Percent_Identity=28.8401253918495, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24583988, Length=334, Percent_Identity=26.6467065868263, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583986, Length=334, Percent_Identity=26.6467065868263, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583984, Length=334, Percent_Identity=26.6467065868263, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658560, Length=407, Percent_Identity=24.3243243243243, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281361666, Length=405, Percent_Identity=25.1851851851852, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24646341, Length=405, Percent_Identity=25.1851851851852, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17136796, Length=405, Percent_Identity=25.1851851851852, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24583992, Length=320, Percent_Identity=26.25, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=53.2608695652174, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_ACIAC (A1TJ41)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968753.1
- ProteinModelPortal:   A1TJ41
- SMR:   A1TJ41
- STRING:   A1TJ41
- GeneID:   4665851
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0372
- NMPDR:   fig|397945.5.peg.335
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   A1TJ41
- ProtClustDB:   PRK09280
- BioCyc:   AAVE397945:AAVE_0372-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51378; Mature: 51247

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQENTQVNAGVQGKIVQCIGAVVDVEFPRDQMPKVYDALKLEGSPLTLEVQQQLGDGVV
CCCCCCEECCCCCHHHHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCEEEEEHHHHCCCCE
RTIALGSSDGLRRGLMVSNTGNPITVPVGKATLGRIMDVLGSPIDERGPVSQELTASIHR
EEEEECCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
KAPAYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHS
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHC
GLSVFAGVGERTREGNDFYHEMADSGVVNLEKLEDSKVAMVYGQMNEPPGNRLRVALTGL
CCCEECCCCCCCCCCCHHHHHHHCCCCEEHHHCCCCCEEEEEECCCCCCCCEEEEEEECH
TIAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITS
HHHHHHHHCCCEEEEEEECHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TKVGSITSIQAVYVPADDLTDPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQL
HCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCCEEEEEHHHHHHCCCCCCCCCCCHHHHC
DPQVVGEEHYQVARGVQGTLQRYKELRDIIAILGMDELAPEDKLAVARARKIQRFLSQPF
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCC
HVAEVFTGSPGKYVPLAETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKVA
EEEHEEECCCCCCCCHHHHHCCEEEEEECCCCCCCHHHEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQENTQVNAGVQGKIVQCIGAVVDVEFPRDQMPKVYDALKLEGSPLTLEVQQQLGDGVV
CCCCCEECCCCCHHHHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCEEEEEHHHHCCCCE
RTIALGSSDGLRRGLMVSNTGNPITVPVGKATLGRIMDVLGSPIDERGPVSQELTASIHR
EEEEECCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
KAPAYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHS
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHC
GLSVFAGVGERTREGNDFYHEMADSGVVNLEKLEDSKVAMVYGQMNEPPGNRLRVALTGL
CCCEECCCCCCCCCCCHHHHHHHCCCCEEHHHCCCCCEEEEEECCCCCCCCEEEEEEECH
TIAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITS
HHHHHHHHCCCEEEEEEECHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TKVGSITSIQAVYVPADDLTDPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQL
HCCCCCEEEEEEEECCCCCCCCCCCCHHHHCCCEEEEEHHHHHHCCCCCCCCCCCHHHHC
DPQVVGEEHYQVARGVQGTLQRYKELRDIIAILGMDELAPEDKLAVARARKIQRFLSQPF
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCC
HVAEVFTGSPGKYVPLAETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKVA
EEEHEEECCCCCCCCHHHHHCCEEEEEECCCCCCCHHHEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA