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The map label for this gene is kdpE [H]

Identifier: 120609062

GI number: 120609062

Start: 388414

End: 389124

Strand: Direct

Name: kdpE [H]

Synonym: Aave_0359

Alternate gene names: 120609062

Gene position: 388414-389124 (Clockwise)

Preceding gene: 120609061

Following gene: 120609063

Centisome position: 7.26

GC content: 73.14

Gene sequence:

>711_bases
ATGACCCAGCACCCGCGCACCGCGATCGTGATCGAGGACGAGCCCCAGATCCGCCGCTTCGTGCGCGGCGCGCTTGAGGA
GGAGGGCTGGCAGGTGCACGAGGCTGCCACGTTGCGCGAGGGGCTGTCGGCTGCCGGCACGCGCCAGCCCGACCTGCTGG
TGCTGGACCTGGGGCTACCCGACGGCGACGGCGTGGCACTGATCCGCGACGTGCGCGGCTGGTCGGCCGTACCCATCATC
GTGCTCTCCGCGCGCACCGACGAGGCGGACAAGATCGCCGCCCTCGACGCGGGCGCGGACGACTACCTCACCAAGCCTTT
CGGCACGGGCGAATTGCTCGCACGCGTGCGCGCCAATCTGCGCAGGCCGCGGCCCGCCACCGGGCAGGGCCTGCAGGCCG
AGGCCGCCGAGCCGGTGTTCCGCTTCGGCGACATCGAGGTGGACCGGGGGGCGCGCCTCGTGCGGCGCGCGGGTACGGTC
GTTCACCTCACGCCCACCGAGTACCGCATGCTCACCGTCCTGGTGGCCAACGCGGGCCGCGTCATCACCCAGCGCCAGCT
GCTGCGCGAGGTCTGGGGCCCGGCGCGTTCCGACCAGAGCCATTACCTGCGCATCTACATGGGCCACCTGCGCCAGAAGC
TGGAGGCCGACCCCGCGCAGCCGCGCCACCTGCTGACCGAGACCGGGGTGGGGTACCGCCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCAACCCGCCTGCCGTGGGGGAAGCCGCCGAGCTCCCGGATGAAGACGCTTCCGACTCCCCCGGGGCCGATCGCAACCTC
TCCTGAATGAATGCCCGCCG

Downstream 100 bases:

>100_bases
CGCTTTGCGGCGGATTGACGCGGCGCGCCGTGCTTTTTACGCCGTTTTGATGCGCCCGTTCCTAGACTGAAGGCCTGTTC
CATCCTGCTTCGCACAAGCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTQHPRTAIVIEDEPQIRRFVRGALEEEGWQVHEAATLREGLSAAGTRQPDLLVLDLGLPDGDGVALIRDVRGWSAVPII
VLSARTDEADKIAALDAGADDYLTKPFGTGELLARVRANLRRPRPATGQGLQAEAAEPVFRFGDIEVDRGARLVRRAGTV
VHLTPTEYRMLTVLVANAGRVITQRQLLREVWGPARSDQSHYLRIYMGHLRQKLEADPAQPRHLLTETGVGYRLAA

Sequences:

>Translated_236_residues
MTQHPRTAIVIEDEPQIRRFVRGALEEEGWQVHEAATLREGLSAAGTRQPDLLVLDLGLPDGDGVALIRDVRGWSAVPII
VLSARTDEADKIAALDAGADDYLTKPFGTGELLARVRANLRRPRPATGQGLQAEAAEPVFRFGDIEVDRGARLVRRAGTV
VHLTPTEYRMLTVLVANAGRVITQRQLLREVWGPARSDQSHYLRIYMGHLRQKLEADPAQPRHLLTETGVGYRLAA
>Mature_235_residues
TQHPRTAIVIEDEPQIRRFVRGALEEEGWQVHEAATLREGLSAAGTRQPDLLVLDLGLPDGDGVALIRDVRGWSAVPIIV
LSARTDEADKIAALDAGADDYLTKPFGTGELLARVRANLRRPRPATGQGLQAEAAEPVFRFGDIEVDRGARLVRRAGTVV
HLTPTEYRMLTVLVANAGRVITQRQLLREVWGPARSDQSHYLRIYMGHLRQKLEADPAQPRHLLTETGVGYRLAA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=61.8421052631579, Blast_Score=291, Evalue=2e-80,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=34.8017621145374, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=32.4786324786325, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=32.0175438596491, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=35.1931330472103, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.1877729257642, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.140350877193, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=34.453781512605, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.0396475770925, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=33.6244541484716, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.4372294372294, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.0175438596491, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=29.6650717703349, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=30.1652892561983, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=105, Percent_Identity=29.5238095238095, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26043; Mature: 25912

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHPRTAIVIEDEPQIRRFVRGALEEEGWQVHEAATLREGLSAAGTRQPDLLVLDLGLP
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC
DGDGVALIRDVRGWSAVPIIVLSARTDEADKIAALDAGADDYLTKPFGTGELLARVRANL
CCCCEEEEEECCCCCCCEEEEEECCCCCCHHEEEECCCCCHHCCCCCCHHHHHHHHHHHH
RRPRPATGQGLQAEAAEPVFRFGDIEVDRGARLVRRAGTVVHLTPTEYRMLTVLVANAGR
CCCCCCCCCCCCCCCCCCHHHCCCEEECHHHHHHHHCCCEEEECCCCCEEEEEEECCCCC
VITQRQLLREVWGPARSDQSHYLRIYMGHLRQKLEADPAQPRHLLTETGVGYRLAA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECC
>Mature Secondary Structure 
TQHPRTAIVIEDEPQIRRFVRGALEEEGWQVHEAATLREGLSAAGTRQPDLLVLDLGLP
CCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC
DGDGVALIRDVRGWSAVPIIVLSARTDEADKIAALDAGADDYLTKPFGTGELLARVRANL
CCCCEEEEEECCCCCCCEEEEEECCCCCCHHEEEECCCCCHHCCCCCCHHHHHHHHHHHH
RRPRPATGQGLQAEAAEPVFRFGDIEVDRGARLVRRAGTVVHLTPTEYRMLTVLVANAGR
CCCCCCCCCCCCCCCCCCHHHCCCEEECHHHHHHHHCCCEEEECCCCCEEEEEEECCCCC
VITQRQLLREVWGPARSDQSHYLRIYMGHLRQKLEADPAQPRHLLTETGVGYRLAA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]