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The map label for this gene is kdpA

Identifier: 120609058

GI number: 120609058

Start: 380918

End: 382723

Strand: Direct

Name: kdpA

Synonym: Aave_0355

Alternate gene names: 120609058

Gene position: 380918-382723 (Clockwise)

Preceding gene: 120609057

Following gene: 120609059

Centisome position: 7.12

GC content: 69.71

Gene sequence:

>1806_bases
ATGACTGCCTCCGCCTGGGGCCTGCTGGCCCTTTTCCTGAGCGTGCTGGGCCTGCTGGCGTGGCCGCTGGGCCGGGGCCT
GGCCGCGGTGTGCGATGGGCGGCTTCCGGGCTGGATGCACCGCGCGGAGGCACCGCTCTATCGCCTGGCCGGCGTGCGGC
CGGAGGCGGGCATGCATTGGCGCCATTACGCGCTGGCGCTGCTGGCCTTCAATGCATTGGGCGTGTTCGCCGTGTATGCC
CTCCAGCGCCTGCAGGGTGTGCTGCCCCTGAATCCGCAGGGACTGCCCGCAGTGGCGGGCGATTCCGCGTTCAACACGGC
CGTGAGCTTCGTGTCGAACACCAACTGGCAGGGGTACGCGGGCGAGTCCACGATGGGCTACCTCGTGCAGATGCTCGGGC
TGTCGGTACAGAACTTCCTGTCCGCTGCGACCGGCATTGCCGTGGCTTTCGCGCTGGCACGGGGTTTCGCCGCGCGCGGT
GGCGATGGGGCCGGGCATGTGGGCAACTTCTGGGCGGACATCGTGCGCATCACGGCCTGGGTGCTGGTGCCGCTGTCCTT
CGTGCTCGCCGTCTTCCTCGCCGGGCAGGGCGTGATCCAGAACTTCACGGCCTACCAAGACGTGGCCACGGTGGAGGCGA
CCGTGTACCAGGACCCGCAATCCGATGCGCAGGGCCAGCCCCTGAAGGACGCGTCCGGCAACCCGCTCACCCGCGAGGTC
CGTACCCGCACGCAGACACTGCCCATGGGGCCCGTCGCGTCGCAGGAGGCGATCAAGATGCTGGGCACGAACGGCGGCGG
ATTCTTCAACGCCAACTCGGCGCATCCCTACGAGAACCCGACGCCGCTCACCAATTTAGCGCAGATGCTGGCGATCTTCC
TGGTTCCCGCGGCGCTGTGCTTCGCGTTCGGCCGGGTGGTGGGGGACTGGCGCCAGGGCGTGGCCATCCTCGCCGCGATG
ACGCTGATGTTCGTGGTGGCCGTGGTCGCGGTGACGGCGGCGGAGCAGGCGGGCAACCCGGCGCTGTCCGCGCTGGGTGC
CGACCCCGTGGCCTCCGCGCTGCAGGCCGGCGGCAACATGGAGGGCAAGGAGGTGCGCTTCGGCATTTCCGCCTCGGCGT
TGTTCGCGGCCGTCACCACCGCCGCTTCCTGCGGCGCCGTCAACGCCATGCACGATTCCTTCACGCCGCTGGGCGGCATG
GTGCCGATGGTGCTCATGCAGCTCGGCGAAGTGGTGTTCGGCGGTGCGGGCTCGGGCCTCTACGGCATGCTGGTGTTCGC
CATCCTCGCGGTGTTCATCGCCGGGCTGATGATCGGGCGCACGCCGGAGTACCTGGGCAAGAAGATCGAGGTGCGCGAGA
TGAAGCTGACCTCCGTCGCCATTCTCGTGACGCCGCTCCTCGTGCTGGTGGGCACCGCCGTGGCCGTGCTGGCGCCCGCG
GGCCAGGCCGGCATCGCGAACCCCGGGGCGCACGGTTTTTCCGAGGTGCTGTATGCGCTCACCTCGGCCGCCAACAACAA
CGGCAGCGCCTTCGCCGGGCTGTCCGCGAACACCCCGTTCTACAACGTGCTGCTGGCCCTGGCCATGTGGTTCGGCCGGT
TCGGCGTGATCGTGCCGGTGCTGGCCATCGCCGGTTCGCTGGCCGCCAAGAAGCGCCTGCCGCCCGGCCCCGGCACCATG
CCCACGCATGGCCCGCTGTTCGTGGCGCTGCTGGTGTTCACGGTGCTGCTCGTGGGGCTGCTGAATTACGTGCCTTCGCT
GGCGCTCGGCCCGGTGGTGGAGCACCTGGTGCTGCAGGCCCGGTGA

Upstream 100 bases:

>100_bases
CGATGATCGGCATCGACGTGCTCTACGGTTTCGGTGGCATCGTCGCGGTGCTGCTGTTCGCCTATCTGGTGTTCGCGCTG
ATCTGCGCGGAGGAGTTCTG

Downstream 100 bases:

>100_bases
GCGGGCGAGGAGAAGAACGACATGACGACCCCCCAATCCCCGGCCACGGCACCCGCCGCGGCCCCGGTTCCCTCGCGGAA
CCTCACGCTGTTCGACGCCG

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTASAWGLLALFLSVLGLLAWPLGRGLAAVCDGRLPGWMHRAEAPLYRLAGVRPEAGMHWRHYALALLAFNALGVFAVYA
LQRLQGVLPLNPQGLPAVAGDSAFNTAVSFVSNTNWQGYAGESTMGYLVQMLGLSVQNFLSAATGIAVAFALARGFAARG
GDGAGHVGNFWADIVRITAWVLVPLSFVLAVFLAGQGVIQNFTAYQDVATVEATVYQDPQSDAQGQPLKDASGNPLTREV
RTRTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPYENPTPLTNLAQMLAIFLVPAALCFAFGRVVGDWRQGVAILAAM
TLMFVVAVVAVTAAEQAGNPALSALGADPVASALQAGGNMEGKEVRFGISASALFAAVTTAASCGAVNAMHDSFTPLGGM
VPMVLMQLGEVVFGGAGSGLYGMLVFAILAVFIAGLMIGRTPEYLGKKIEVREMKLTSVAILVTPLLVLVGTAVAVLAPA
GQAGIANPGAHGFSEVLYALTSAANNNGSAFAGLSANTPFYNVLLALAMWFGRFGVIVPVLAIAGSLAAKKRLPPGPGTM
PTHGPLFVALLVFTVLLVGLLNYVPSLALGPVVEHLVLQAR

Sequences:

>Translated_601_residues
MTASAWGLLALFLSVLGLLAWPLGRGLAAVCDGRLPGWMHRAEAPLYRLAGVRPEAGMHWRHYALALLAFNALGVFAVYA
LQRLQGVLPLNPQGLPAVAGDSAFNTAVSFVSNTNWQGYAGESTMGYLVQMLGLSVQNFLSAATGIAVAFALARGFAARG
GDGAGHVGNFWADIVRITAWVLVPLSFVLAVFLAGQGVIQNFTAYQDVATVEATVYQDPQSDAQGQPLKDASGNPLTREV
RTRTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPYENPTPLTNLAQMLAIFLVPAALCFAFGRVVGDWRQGVAILAAM
TLMFVVAVVAVTAAEQAGNPALSALGADPVASALQAGGNMEGKEVRFGISASALFAAVTTAASCGAVNAMHDSFTPLGGM
VPMVLMQLGEVVFGGAGSGLYGMLVFAILAVFIAGLMIGRTPEYLGKKIEVREMKLTSVAILVTPLLVLVGTAVAVLAPA
GQAGIANPGAHGFSEVLYALTSAANNNGSAFAGLSANTPFYNVLLALAMWFGRFGVIVPVLAIAGSLAAKKRLPPGPGTM
PTHGPLFVALLVFTVLLVGLLNYVPSLALGPVVEHLVLQAR
>Mature_600_residues
TASAWGLLALFLSVLGLLAWPLGRGLAAVCDGRLPGWMHRAEAPLYRLAGVRPEAGMHWRHYALALLAFNALGVFAVYAL
QRLQGVLPLNPQGLPAVAGDSAFNTAVSFVSNTNWQGYAGESTMGYLVQMLGLSVQNFLSAATGIAVAFALARGFAARGG
DGAGHVGNFWADIVRITAWVLVPLSFVLAVFLAGQGVIQNFTAYQDVATVEATVYQDPQSDAQGQPLKDASGNPLTREVR
TRTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPYENPTPLTNLAQMLAIFLVPAALCFAFGRVVGDWRQGVAILAAMT
LMFVVAVVAVTAAEQAGNPALSALGADPVASALQAGGNMEGKEVRFGISASALFAAVTTAASCGAVNAMHDSFTPLGGMV
PMVLMQLGEVVFGGAGSGLYGMLVFAILAVFIAGLMIGRTPEYLGKKIEVREMKLTSVAILVTPLLVLVGTAVAVLAPAG
QAGIANPGAHGFSEVLYALTSAANNNGSAFAGLSANTPFYNVLLALAMWFGRFGVIVPVLAIAGSLAAKKRLPPGPGTMP
THGPLFVALLVFTVLLVGLLNYVPSLALGPVVEHLVLQAR

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family

Homologues:

Organism=Escherichia coli, GI1786915, Length=597, Percent_Identity=59.9664991624791, Blast_Score=659, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATKA_ACIAC (A1TJ24)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968736.1
- STRING:   A1TJ24
- GeneID:   4666100
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0355
- NMPDR:   fig|397945.5.peg.320
- eggNOG:   COG2060
- HOGENOM:   HBG291815
- OMA:   MSYLTQM
- PhylomeDB:   A1TJ24
- ProtClustDB:   PRK05482
- BioCyc:   AAVE397945:AAVE_0355-MONOMER
- HAMAP:   MF_00275
- InterPro:   IPR004623
- PIRSF:   PIRSF001294
- TIGRFAMs:   TIGR00680

Pfam domain/function: PF03814 KdpA

EC number: =3.6.3.12

Molecular weight: Translated: 62196; Mature: 62065

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe0cc150)-; HASH(0x10067968)-; HASH(0x1105dc80)-; HASH(0xffc71c4)-; HASH(0x10d9b9f4)-; HASH(0x110760d4)-; HASH(0xc4d8d08)-; HASH(0x1109643c)-; HASH(0x111208f4)-; HASH(0x10f2a968)-; HASH(0x1079a3b4)-; HASH(0x102f45d0)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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H
>Mature Secondary Structure 
TASAWGLLALFLSVLGLLAWPLGRGLAAVCDGRLPGWMHRAEAPLYRLAGVRPEAGMHW
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCHHHHCCCCCCCCCHH
RHYALALLAFNALGVFAVYALQRLQGVLPLNPQGLPAVAGDSAFNTAVSFVSNTNWQGYA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
GESTMGYLVQMLGLSVQNFLSAATGIAVAFALARGFAARGGDGAGHVGNFWADIVRITAW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
VLVPLSFVLAVFLAGQGVIQNFTAYQDVATVEATVYQDPQSDAQGQPLKDASGNPLTREV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHH
RTRTQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPYENPTPLTNLAQMLAIFLVPAALC
HHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FAFGRVVGDWRQGVAILAAMTLMFVVAVVAVTAAEQAGNPALSALGADPVASALQAGGNM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCC
EGKEVRFGISASALFAAVTTAASCGAVNAMHDSFTPLGGMVPMVLMQLGEVVFGGAGSGL
CCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCH
YGMLVFAILAVFIAGLMIGRTPEYLGKKIEVREMKLTSVAILVTPLLVLVGTAVAVLAPA
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQAGIANPGAHGFSEVLYALTSAANNNGSAFAGLSANTPFYNVLLALAMWFGRFGVIVPV
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAIAGSLAAKKRLPPGPGTMPTHGPLFVALLVFTVLLVGLLNYVPSLALGPVVEHLVLQA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
R
H

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA