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The map label for this gene is manX [C]

Identifier: 120609055

GI number: 120609055

Start: 378005

End: 378457

Strand: Direct

Name: manX [C]

Synonym: Aave_0352

Alternate gene names: 120609055

Gene position: 378005-378457 (Clockwise)

Preceding gene: 120609054

Following gene: 120609056

Centisome position: 7.06

GC content: 70.42

Gene sequence:

>453_bases
ATGAGCACGCGCATCCTCCTCATCGCCCACGCCCCGCTGGCCCATGCGCTGCGCGCCTGCGCCCTGCACGTGTTCCCCGA
TACCGCCGACGACATCCTGGCGCTCGACGTGCATCCGAATGCCCCTCCGGAGGACACGCTGGCTGCCGCGCGCATCCTGC
TCGACGGGGCGGGCGGGGACGCTCCCATCCTCGTGCTGACGGACGTGTTCGGCGCGACCCCGTGCAACGTGGCCCAGCGC
CTCGTGGACGGGGAGCGCTCGCGGCTGGTCACCGGGGTGAACCTGCCGATGCTGTTGCGCGCGGTGAGCTACCGCCGCGA
GCCGCTCGAGGCGCTCGTCGCCCGCGCGATCGCGGGCGGCACCCAGGGGGTGATGCAGGTCGCTGTGGCCGCGCCACAGA
ACCAGACACGACGGTCCCACCATGATCAAGACGAATATCACCATCAGCAATAA

Upstream 100 bases:

>100_bases
CTCTACCACGCGGTGATCTACAGCCCGCAACCGCGGGCTGCGGTGGCGGACACGTTCTTCCCCGGGCTCGCATTGCGATA
ATGCGGCCCATCGATTCCCC

Downstream 100 bases:

>100_bases
GCTGGGCCTGCACGCCCGGGCATCCGCCAAACTCACCAAACTGGCGGGCAGCTTTCCCTGCGAGGTGTGGATGGCCCGGG
GCGAGCGCCGCGTGAATGCC

Product: PTS system fructose subfamily transporter subunit IIA

Products: protein histidine; sugar phosphate

Alternate protein names: PTS System Fructose-Specific IIA Component; IIA Component Of Sugar Transport PTS System; Protein-N P-Phosphohistidine-Sugar Phosphotransferase; Sugar Transport PTS System IIA Component; PTS System Fructose Subfamily Transporter Subunit IIA; PTS System Fructose IIA Component Family Protein; Pts System IIa Component; Pts System Fructose Subfamily IIa Component; Phosphotransferase Mannose/Fructose-Specific Component IIA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSTRILLIAHAPLAHALRACALHVFPDTADDILALDVHPNAPPEDTLAAARILLDGAGGDAPILVLTDVFGATPCNVAQR
LVDGERSRLVTGVNLPMLLRAVSYRREPLEALVARAIAGGTQGVMQVAVAAPQNQTRRSHHDQDEYHHQQ

Sequences:

>Translated_150_residues
MSTRILLIAHAPLAHALRACALHVFPDTADDILALDVHPNAPPEDTLAAARILLDGAGGDAPILVLTDVFGATPCNVAQR
LVDGERSRLVTGVNLPMLLRAVSYRREPLEALVARAIAGGTQGVMQVAVAAPQNQTRRSHHDQDEYHHQQ
>Mature_149_residues
STRILLIAHAPLAHALRACALHVFPDTADDILALDVHPNAPPEDTLAAARILLDGAGGDAPILVLTDVFGATPCNVAQRL
VDGERSRLVTGVNLPMLLRAVSYRREPLEALVARAIAGGTQGVMQVAVAAPQNQTRRSHHDQDEYHHQQ

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 16069; Mature: 15937

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRILLIAHAPLAHALRACALHVFPDTADDILALDVHPNAPPEDTLAAARILLDGAGGD
CCCEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHEECCCCC
APILVLTDVFGATPCNVAQRLVDGERSRLVTGVNLPMLLRAVSYRREPLEALVARAIAGG
CCEEEEECCCCCCHHHHHHHHHCCCHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCC
TQGVMQVAVAAPQNQTRRSHHDQDEYHHQQ
HHHHHHHHHCCCCCHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
STRILLIAHAPLAHALRACALHVFPDTADDILALDVHPNAPPEDTLAAARILLDGAGGD
CCEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHEECCCCC
APILVLTDVFGATPCNVAQRLVDGERSRLVTGVNLPMLLRAVSYRREPLEALVARAIAGG
CCEEEEECCCCCCHHHHHHHHHCCCHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCC
TQGVMQVAVAAPQNQTRRSHHDQDEYHHQQ
HHHHHHHHHCCCCCHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA