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The map label for this gene is fusA1 [H]

Identifier: 120609038

GI number: 120609038

Start: 366338

End: 368440

Strand: Direct

Name: fusA1 [H]

Synonym: Aave_0335

Alternate gene names: 120609038

Gene position: 366338-368440 (Clockwise)

Preceding gene: 120609037

Following gene: 120609039

Centisome position: 6.84

GC content: 63.29

Gene sequence:

>2103_bases
ATGGCACGCAAGACTCCCATCGAGCGCTACCGCAACATCGGTATCTCGGCCCACATCGACGCTGGCAAGACCACGACGAC
TGAACGTATCCTGTTCTACACGGGTGTGAACCACAAGATCGGCGAAGTGCACGACGGCGCTGCGACCATGGACTGGATGG
AGCAGGAGCAGGAGCGCGGCATCACGATCACGTCCGCCGCCACGACCTGCTTCTGGAAGGGCATGGACATGTCCTACCCC
GAGCACCGCTTCAACATCATCGACACCCCCGGCCACGTGGACTTCACCATCGAGGTGGAGCGTTCCATGCGCGTGCTGGA
CGGTGCCTGCATGGTCTATTGCGCCGTGGGTGGCGTGCAGCCCCAGTCGGAAACCGTCTGGCGCCAGGCCAACAAGTACA
AGGTGCCCCGCCTCGCGTTCGTCAACAAGATGGACCGTACCGGCGCCAACTTCTTCAAGGTCTATGACCAGATGCGCCTG
CGCCTGAAGGCCAACCCCGTGCCCGTCGTGATCCCGATCGGCGCCGAGGAAGGTTTCAAGGGCGTGGTCGATCTGCTCAA
GATGAAGGCCATCATCTGGGACGAAGCCTCCCAGGGCATGAAGTTCAACTACGAAGAGATCCCGGCCGACCTGGCGGAGT
CCGCCAAGGAATGGCGCGAGAAGATGGTCGAGGCCGCTGCCGAAGCGTCCGAAGAGCTGATGAACAAGTACCTGGAAGAG
GGCGACCTCTCCGAGGAAGAGATCAAGCTCGGCCTGCGCACGCGCACGATCGCCACCGAGATCCAGCCCATGCTGTGCGG
CACGGCGTTCAAGAACAAGGGCGTGCAGCGCATGCTGGACGCCGTGATCGACTACCTGCCTTCGCCCGTGGACATCCCGC
CCGTGGCCGGCACGGACGAAGACGAAGCCGAAACCACCCGCAAGGCGGATGACAACGAGAAGTTCTCGGCCCTCGCATTC
AAGCTGATGACCGACCCGTTCGTGGGCCAGCTGACCTTCGTGCGCGTGTATTCGGGCGTGCTCTCCAAGGGCGACAGCGT
TTACAACCCCGTCAAGGGCAAGAAGGAGCGCATCGGCCGTATCGTGCAGATGCACGCCAACGAACGCCTGGAAGTGGAAG
AAATCCGCGCCGGCGACATCGCCGCCTGCGTGGGCCTGAAGGACGTGACCACGGGTGAAACCCTGTGCGATCCCGAAGCC
ATCGTGACGCTGGAGCGCATGGTGTTCCCCGAGCCCGTGATCGCGCAGGCCGTGGAGCCCAAGACCAAGACCGACCAGGA
AAAGATGGGCATCGCGCTGCAGCGCCTGGCCGCCGAAGATCCGTCCTTCCGCGTGAAGACCGACGAGGAATCCGGCCAGA
CCATCATCTCGGGCATGGGCGAGCTCCACCTCGAAATCATCGTGGACCGCATGAAGCGCGAGTTCGGCGTGGAAGCCAAC
GTGGGCAAGCCGCAGGTGGCCTACCGCGAAACCATCCGCAAGACGGTGGAAGAGGCCGAAGGCAAGTTCGTGCGCCAGTC
CGGCGGCAAGGGCCAGTACGGCCACGTCGTGCTCAAGATCGAGCCGAACGAAGCCGGCAAGGGCATCGAGTTCGTGGACG
CCATCAAGGGCGGTGTGGTTCCCCGTGAATTCATCCCGGCCGTGGAAAAGGGCATCAACGAAGCCGTGACCCAGGGCGTG
CTGGCCGGCTATCCGGTGGTGGACGTGAAGGTCACGCTGCACTTCGGTTCGTACCACGACGTGGACTCGAACGAACTGGC
GTTCAAGATGGCCGCCATCTTCGGCTTCAAGGAAGGTTGCAAGAAGGCCGGTCCGGTCATCCTGGAACCCATGATGGCCG
TGGAAGTGGAGACGCCCGAAGACTACGCCGGTACCGTGATGGGCGACCTCTCGTCCCGCCGCGGCATGGTGCAGGGCATG
GACGACATGGTCGGCGGCGGCAAGGCCATCAAGGCCGAAGTGCCCCTGTCGGAAATGTTCGGCTACTCGACCGCGCTGCG
CTCCGCGACGCAAGGCCGTGCCACGTACACGATGGAGTTCAAGCACTACAGCGAAGCTCCGCGCAACGTGTCCGAAGCCA
TCATGGCCGCCCGCGCGAAGTAA

Upstream 100 bases:

>100_bases
AGCCACTTCCGCTTCTAAGCCCATCCCTTCATCTCGAAGGCCTGGAGCCCGATCCGCCCCACCGGCGGGCGGGCTCTTTG
GCTGTTAACGAAAGACCATC

Downstream 100 bases:

>100_bases
GTACCACCCCTGTGTCGCCTGCGGCGCCTCCCCCTCAAGGGGGCGCACGCAGCGGTCCGGCAAAGCCGGTCCCGCGCGTG
CCGCTGGCGTGGCCTGCTCC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G 1 [H]

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMDMSYP
EHRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQMRL
RLKANPVPVVIPIGAEEGFKGVVDLLKMKAIIWDEASQGMKFNYEEIPADLAESAKEWREKMVEAAAEASEELMNKYLEE
GDLSEEEIKLGLRTRTIATEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPVDIPPVAGTDEDEAETTRKADDNEKFSALAF
KLMTDPFVGQLTFVRVYSGVLSKGDSVYNPVKGKKERIGRIVQMHANERLEVEEIRAGDIAACVGLKDVTTGETLCDPEA
IVTLERMVFPEPVIAQAVEPKTKTDQEKMGIALQRLAAEDPSFRVKTDEESGQTIISGMGELHLEIIVDRMKREFGVEAN
VGKPQVAYRETIRKTVEEAEGKFVRQSGGKGQYGHVVLKIEPNEAGKGIEFVDAIKGGVVPREFIPAVEKGINEAVTQGV
LAGYPVVDVKVTLHFGSYHDVDSNELAFKMAAIFGFKEGCKKAGPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGM
DDMVGGGKAIKAEVPLSEMFGYSTALRSATQGRATYTMEFKHYSEAPRNVSEAIMAARAK

Sequences:

>Translated_700_residues
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMDMSYP
EHRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQMRL
RLKANPVPVVIPIGAEEGFKGVVDLLKMKAIIWDEASQGMKFNYEEIPADLAESAKEWREKMVEAAAEASEELMNKYLEE
GDLSEEEIKLGLRTRTIATEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPVDIPPVAGTDEDEAETTRKADDNEKFSALAF
KLMTDPFVGQLTFVRVYSGVLSKGDSVYNPVKGKKERIGRIVQMHANERLEVEEIRAGDIAACVGLKDVTTGETLCDPEA
IVTLERMVFPEPVIAQAVEPKTKTDQEKMGIALQRLAAEDPSFRVKTDEESGQTIISGMGELHLEIIVDRMKREFGVEAN
VGKPQVAYRETIRKTVEEAEGKFVRQSGGKGQYGHVVLKIEPNEAGKGIEFVDAIKGGVVPREFIPAVEKGINEAVTQGV
LAGYPVVDVKVTLHFGSYHDVDSNELAFKMAAIFGFKEGCKKAGPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGM
DDMVGGGKAIKAEVPLSEMFGYSTALRSATQGRATYTMEFKHYSEAPRNVSEAIMAARAK
>Mature_699_residues
ARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMDMSYPE
HRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQMRLR
LKANPVPVVIPIGAEEGFKGVVDLLKMKAIIWDEASQGMKFNYEEIPADLAESAKEWREKMVEAAAEASEELMNKYLEEG
DLSEEEIKLGLRTRTIATEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPVDIPPVAGTDEDEAETTRKADDNEKFSALAFK
LMTDPFVGQLTFVRVYSGVLSKGDSVYNPVKGKKERIGRIVQMHANERLEVEEIRAGDIAACVGLKDVTTGETLCDPEAI
VTLERMVFPEPVIAQAVEPKTKTDQEKMGIALQRLAAEDPSFRVKTDEESGQTIISGMGELHLEIIVDRMKREFGVEANV
GKPQVAYRETIRKTVEEAEGKFVRQSGGKGQYGHVVLKIEPNEAGKGIEFVDAIKGGVVPREFIPAVEKGINEAVTQGVL
AGYPVVDVKVTLHFGSYHDVDSNELAFKMAAIFGFKEGCKKAGPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGMD
DMVGGGKAIKAEVPLSEMFGYSTALRSATQGRATYTMEFKHYSEAPRNVSEAIMAARAK

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=703, Percent_Identity=45.0924608819346, Blast_Score=569, Evalue=1e-162,
Organism=Homo sapiens, GI19923640, Length=720, Percent_Identity=39.8611111111111, Blast_Score=470, Evalue=1e-132,
Organism=Homo sapiens, GI25306287, Length=720, Percent_Identity=37.7777777777778, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI25306283, Length=401, Percent_Identity=43.640897755611, Blast_Score=308, Evalue=2e-83,
Organism=Homo sapiens, GI4503483, Length=826, Percent_Identity=25.6658595641646, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI157426893, Length=153, Percent_Identity=33.9869281045752, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI94966754, Length=136, Percent_Identity=38.2352941176471, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI310132016, Length=120, Percent_Identity=38.3333333333333, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI310110807, Length=120, Percent_Identity=38.3333333333333, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI310123363, Length=120, Percent_Identity=38.3333333333333, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI1789738, Length=705, Percent_Identity=72.0567375886525, Blast_Score=1038, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=493, Percent_Identity=27.3833671399594, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI48994988, Length=182, Percent_Identity=36.2637362637363, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788922, Length=140, Percent_Identity=37.1428571428571, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17533571, Length=691, Percent_Identity=41.534008683068, Blast_Score=518, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17556745, Length=728, Percent_Identity=30.0824175824176, Blast_Score=315, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI17506493, Length=825, Percent_Identity=27.1515151515152, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17557151, Length=206, Percent_Identity=32.0388349514563, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988819, Length=146, Percent_Identity=32.1917808219178, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988811, Length=146, Percent_Identity=32.1917808219178, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=697, Percent_Identity=42.6111908177905, Blast_Score=553, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6322359, Length=793, Percent_Identity=30.8953341740227, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6324707, Length=836, Percent_Identity=25.5980861244019, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320593, Length=836, Percent_Identity=25.5980861244019, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323320, Length=226, Percent_Identity=30.0884955752212, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=144, Percent_Identity=37.5, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582462, Length=706, Percent_Identity=45.3257790368272, Blast_Score=594, Evalue=1e-170,
Organism=Drosophila melanogaster, GI221458488, Length=740, Percent_Identity=32.027027027027, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24585709, Length=822, Percent_Identity=25.9124087591241, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24585711, Length=822, Percent_Identity=25.9124087591241, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24585713, Length=822, Percent_Identity=25.9124087591241, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI78706572, Length=161, Percent_Identity=35.4037267080745, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28574573, Length=142, Percent_Identity=35.9154929577465, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 77383; Mature: 77251

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTCFWKGMDMSYPEHRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQ
EEEEECHHHHEECCCCCCCCCCCCEEECCCCCEEEEEEECHHHHHHHHHHEEEEECCCCC
PQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQMRLRLKANPVPVVIPIGAEEGFK
CCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCEEEEECCCCCCHH
GVVDLLKMKAIIWDEASQGMKFNYEEIPADLAESAKEWREKMVEAAAEASEELMNKYLEE
HHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLSEEEIKLGLRTRTIATEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPVDIPPVAGTDE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
DEAETTRKADDNEKFSALAFKLMTDPFVGQLTFVRVYSGVLSKGDSVYNPVKGKKERIGR
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IVQMHANERLEVEEIRAGDIAACVGLKDVTTGETLCDPEAIVTLERMVFPEPVIAQAVEP
HHHHHCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCC
KTKTDQEKMGIALQRLAAEDPSFRVKTDEESGQTIISGMGELHLEIIVDRMKREFGVEAN
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VGKPQVAYRETIRKTVEEAEGKFVRQSGGKGQYGHVVLKIEPNEAGKGIEFVDAIKGGVV
CCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCC
PREFIPAVEKGINEAVTQGVLAGYPVVDVKVTLHFGSYHDVDSNELAFKMAAIFGFKEGC
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KKAGPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGMDDMVGGGKAIKAEVPLSEMF
HHCCCEEECCEEEEEECCCCCCCCHHHHHHHHHCCHHHCHHHHCCCCCEEEECCCHHHHH
GYSTALRSATQGRATYTMEFKHYSEAPRNVSEAIMAARAK
HHHHHHHHHCCCCEEEEEEEHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTCFWKGMDMSYPEHRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQ
EEEEECHHHHEECCCCCCCCCCCCEEECCCCCEEEEEEECHHHHHHHHHHEEEEECCCCC
PQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQMRLRLKANPVPVVIPIGAEEGFK
CCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCEEEEECCCCCCHH
GVVDLLKMKAIIWDEASQGMKFNYEEIPADLAESAKEWREKMVEAAAEASEELMNKYLEE
HHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLSEEEIKLGLRTRTIATEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPVDIPPVAGTDE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
DEAETTRKADDNEKFSALAFKLMTDPFVGQLTFVRVYSGVLSKGDSVYNPVKGKKERIGR
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IVQMHANERLEVEEIRAGDIAACVGLKDVTTGETLCDPEAIVTLERMVFPEPVIAQAVEP
HHHHHCCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCC
KTKTDQEKMGIALQRLAAEDPSFRVKTDEESGQTIISGMGELHLEIIVDRMKREFGVEAN
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VGKPQVAYRETIRKTVEEAEGKFVRQSGGKGQYGHVVLKIEPNEAGKGIEFVDAIKGGVV
CCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCC
PREFIPAVEKGINEAVTQGVLAGYPVVDVKVTLHFGSYHDVDSNELAFKMAAIFGFKEGC
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KKAGPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGMDDMVGGGKAIKAEVPLSEMF
HHCCCEEECCEEEEEECCCCCCCCHHHHHHHHHCCHHHCHHHHCCCCCEEEECCCHHHHH
GYSTALRSATQGRATYTMEFKHYSEAPRNVSEAIMAARAK
HHHHHHHHHCCCCEEEEEEEHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA