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The map label for this gene is dinG [H]

Identifier: 120608726

GI number: 120608726

Start: 12900

End: 15125

Strand: Direct

Name: dinG [H]

Synonym: Aave_0013

Alternate gene names: 120608726

Gene position: 12900-15125 (Clockwise)

Preceding gene: 120608724

Following gene: 120608727

Centisome position: 0.24

GC content: 72.55

Gene sequence:

>2226_bases
ATGTCTCAACAGGAGTGGGCCGCGCAGGCCCTGCAGTCTTTCGATGCGGTGGTGCAGGCCACCGAGGGCTTGCGCAGCCG
CGGCGGGCAGCGGCGCATGGCCGAGCAGGTGGCGCACACGTTCGCGCGGGCACAGCTCGGCAAGGTGGAGGCCGAAGACG
GCGACAGCGCGCCTGCGCCGCCCGCGCGCTCCATCGCGGTGGTGCAGGCCGGGACGGGCGTGGGCAAATCGCTCGCCTAC
AGCGTGCCGGCGATCGCCATGGCGCTTGCGCGCGGTACGCGCGTGCTGATTTCCACGGCCACCGTGGCGCTGCAGGAACA
GCTCGTGCAGAAGGACCTGCCGGCGCTCGCGGCCCGCATGCCGCAGCCCTTCCAGTTCGCGCTGGCCAAGGGGCGCGGCC
GCTACGTGTGCAAGCTCAAGCTGGAGCGCCTGGCAGGCACCGGGGAGGCCGGTGACGAGGGGCCCGAGGACGACCTGTTC
GCCGAGGAGGAGGCCGCGGCCCGCGCCGCCCGCCCGCGCCACGAGACCGAGGCACGCATGAAGTTCTACGCCACCATGGC
CGACGTGCTCGCGCGCGGCGCATGGGACGGCGACCGCGACACGCTGGAATCCCCGCCCGAGCCCGAGGTCTGGAGCCCGG
TGGCGGCCGAGGCCAGTTCCTGCACCGGCAAGCACTGCCCGGCCTTCGGCCAGTGCACCTACTACGACCGGCGCAAGGCA
CTGGTGGCCGCGCAGGTGATCGTGGCCAACCACGACCTGCTGCTGTCCTCGATCGGGGCGCGGCTGCTGCCCGAGCTGGA
CAACTGCCTGCTCGTGGTGGACGAAGCCCACCACCTGCCCTCCACCGCGCTCGACCAGTTCGCCTGCGAGGCGGACCTGA
GCCGGCTGAACTGGATCGACAAGCTCGCGAGCCGCGCGCTGCGCATCGGCACGCTGATGGAAGTCGAGGAAGTGGCGGAC
ATCCCCAACCATTCCGCCCGGCTGCGCGCCGCGCTGCAGGACGCGGCGCGCATGGTCATGGACGTGTACGGCGACGAACT
GCGCGCACCGCGGCCCGCCTGGGGCGGAGGGCGCACCGCATCCACGCAATCCTCCCGCATTCCCGCGGCCGCGGCGCCCA
CGCGCGCACGCGTCCCGGGAGGCGCGCTGCCCGAGGCGCTGGTGGAGCCCTTCAGCCAGGTGGCGCACCATGCGGCGGGC
TTTCTCGACGCGCTGCGCGCCATCGCCAAGGCGCTGCGCTCGGAAATGCGCGACAAGCCCGACGAGGCGCGGCGCCTGTC
CACGCTCTATGCGCAGATCGGCGCGCTCGCGCCCCGGCTGGAGGGCGTGCACGACACGGCCCAGCTGCTGCTGCAGGACG
CGCCGGAGGGCGCCGTGCCGGCAGCCAAGTGGTTCACGCTGGCGGTGGATGGCGACTTCATCGTCGTCAAGGCCCATGCC
AGCCCGGTACTGCCGGGCAATACGCTGCGCAACCACCTGTGGTCGGCCGTGCGCGGGGCCGTGCTCACCTCGGCCACGCT
CACGAGCTGCGGCCAGTTCGATTTCTTCCTGCGCGAGGCCGGCCTGCACGGCGACGACGCCGTCACCACCCTGGAAGTGC
CTAGCCCCTTCGACTATGCGCTGCAGGGCACGCTCGTGGCCACCGAGACCCAGGCCGATCCCCGGCAGGCGGCCGACTAC
ACCGCAGAAATGGTGGACGCGCTGCTGAGCGACCTCGCCATGGTCGAGGCCGGCGCCCTGGTGCTGTTCACCTCGCGCGA
CCAGATGCGGCAGGCCGTGGACGCACTGCCCACCGCCATGCGCAGCACGGTGCTGGTGCAGACGCAGATGCCGCGTTCCC
AGCTGCTGGCACGGCACCGCGAGCGCGTGGCGGCGGGCGAGCCGTCGATCATCTTCGGCATGCAGTCCTTCGGCGAGGGG
CTGGACCTGCCCGGGGCGCTCTGCGAATCGCTCTTCATCACCAAGCTGCCTTTCGCGCCGCCGGACGACCCGGTGGGCGA
GGCGCGGGCCGAGTGGCTGCGCGGCACGGGGCGCGACCCGTTCAGCGAACTCGTGGTGCCCGCCACGGCCATCCGGCTCG
CCCAGTGGGTGGGACGCGCCATCCGCACCGAGGAAGACCGCGCCCACGTCTATTGCTACGACAGGCGTCTGGTGCGCACG
GCCTACGGCCAGCGGCTGCTCAAGGGCCTGCCGCCGTTCACGCTGCAGCGCCGCACCGCGGCGTAG

Upstream 100 bases:

>100_bases
TGGCAGGCAGCTCGGGGTCTGTGGCTTTCCATGCTAGAAAGCGGGCCGCGCCCCGTCTGTAGTCCGCCGCGCACTGGCCT
GGCCGGTACACTACCACTGT

Downstream 100 bases:

>100_bases
CGCGCTTGGCGCGGGTCCAGGCGCTGGGCATCGGCGCCGCGGTGTCGGACGCACCCGACAGCCATGCGGCGGCGGGGCCG
ACCCCGGCAGGACTGCATGC

Product: ATP-dependent DNA helicase DinG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MSQQEWAAQALQSFDAVVQATEGLRSRGGQRRMAEQVAHTFARAQLGKVEAEDGDSAPAPPARSIAVVQAGTGVGKSLAY
SVPAIAMALARGTRVLISTATVALQEQLVQKDLPALAARMPQPFQFALAKGRGRYVCKLKLERLAGTGEAGDEGPEDDLF
AEEEAAARAARPRHETEARMKFYATMADVLARGAWDGDRDTLESPPEPEVWSPVAAEASSCTGKHCPAFGQCTYYDRRKA
LVAAQVIVANHDLLLSSIGARLLPELDNCLLVVDEAHHLPSTALDQFACEADLSRLNWIDKLASRALRIGTLMEVEEVAD
IPNHSARLRAALQDAARMVMDVYGDELRAPRPAWGGGRTASTQSSRIPAAAAPTRARVPGGALPEALVEPFSQVAHHAAG
FLDALRAIAKALRSEMRDKPDEARRLSTLYAQIGALAPRLEGVHDTAQLLLQDAPEGAVPAAKWFTLAVDGDFIVVKAHA
SPVLPGNTLRNHLWSAVRGAVLTSATLTSCGQFDFFLREAGLHGDDAVTTLEVPSPFDYALQGTLVATETQADPRQAADY
TAEMVDALLSDLAMVEAGALVLFTSRDQMRQAVDALPTAMRSTVLVQTQMPRSQLLARHRERVAAGEPSIIFGMQSFGEG
LDLPGALCESLFITKLPFAPPDDPVGEARAEWLRGTGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDRRLVRT
AYGQRLLKGLPPFTLQRRTAA

Sequences:

>Translated_741_residues
MSQQEWAAQALQSFDAVVQATEGLRSRGGQRRMAEQVAHTFARAQLGKVEAEDGDSAPAPPARSIAVVQAGTGVGKSLAY
SVPAIAMALARGTRVLISTATVALQEQLVQKDLPALAARMPQPFQFALAKGRGRYVCKLKLERLAGTGEAGDEGPEDDLF
AEEEAAARAARPRHETEARMKFYATMADVLARGAWDGDRDTLESPPEPEVWSPVAAEASSCTGKHCPAFGQCTYYDRRKA
LVAAQVIVANHDLLLSSIGARLLPELDNCLLVVDEAHHLPSTALDQFACEADLSRLNWIDKLASRALRIGTLMEVEEVAD
IPNHSARLRAALQDAARMVMDVYGDELRAPRPAWGGGRTASTQSSRIPAAAAPTRARVPGGALPEALVEPFSQVAHHAAG
FLDALRAIAKALRSEMRDKPDEARRLSTLYAQIGALAPRLEGVHDTAQLLLQDAPEGAVPAAKWFTLAVDGDFIVVKAHA
SPVLPGNTLRNHLWSAVRGAVLTSATLTSCGQFDFFLREAGLHGDDAVTTLEVPSPFDYALQGTLVATETQADPRQAADY
TAEMVDALLSDLAMVEAGALVLFTSRDQMRQAVDALPTAMRSTVLVQTQMPRSQLLARHRERVAAGEPSIIFGMQSFGEG
LDLPGALCESLFITKLPFAPPDDPVGEARAEWLRGTGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDRRLVRT
AYGQRLLKGLPPFTLQRRTAA
>Mature_740_residues
SQQEWAAQALQSFDAVVQATEGLRSRGGQRRMAEQVAHTFARAQLGKVEAEDGDSAPAPPARSIAVVQAGTGVGKSLAYS
VPAIAMALARGTRVLISTATVALQEQLVQKDLPALAARMPQPFQFALAKGRGRYVCKLKLERLAGTGEAGDEGPEDDLFA
EEEAAARAARPRHETEARMKFYATMADVLARGAWDGDRDTLESPPEPEVWSPVAAEASSCTGKHCPAFGQCTYYDRRKAL
VAAQVIVANHDLLLSSIGARLLPELDNCLLVVDEAHHLPSTALDQFACEADLSRLNWIDKLASRALRIGTLMEVEEVADI
PNHSARLRAALQDAARMVMDVYGDELRAPRPAWGGGRTASTQSSRIPAAAAPTRARVPGGALPEALVEPFSQVAHHAAGF
LDALRAIAKALRSEMRDKPDEARRLSTLYAQIGALAPRLEGVHDTAQLLLQDAPEGAVPAAKWFTLAVDGDFIVVKAHAS
PVLPGNTLRNHLWSAVRGAVLTSATLTSCGQFDFFLREAGLHGDDAVTTLEVPSPFDYALQGTLVATETQADPRQAADYT
AEMVDALLSDLAMVEAGALVLFTSRDQMRQAVDALPTAMRSTVLVQTQMPRSQLLARHRERVAAGEPSIIFGMQSFGEGL
DLPGALCESLFITKLPFAPPDDPVGEARAEWLRGTGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDRRLVRTA
YGQRLLKGLPPFTLQRRTAA

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787018, Length=746, Percent_Identity=30.4289544235925, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI1788110, Length=233, Percent_Identity=34.7639484978541, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010614
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650 [H]

Pfam domain/function: PF06733 DEAD_2 [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79907; Mature: 79775

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQEWAAQALQSFDAVVQATEGLRSRGGQRRMAEQVAHTFARAQLGKVEAEDGDSAPAP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PARSIAVVQAGTGVGKSLAYSVPAIAMALARGTRVLISTATVALQEQLVQKDLPALAARM
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHC
PQPFQFALAKGRGRYVCKLKLERLAGTGEAGDEGPEDDLFAEEEAAARAARPRHETEARM
CCCHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
KFYATMADVLARGAWDGDRDTLESPPEPEVWSPVAAEASSCTGKHCPAFGQCTYYDRRKA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH
LVAAQVIVANHDLLLSSIGARLLPELDNCLLVVDEAHHLPSTALDQFACEADLSRLNWID
HHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
KLASRALRIGTLMEVEEVADIPNHSARLRAALQDAARMVMDVYGDELRAPRPAWGGGRTA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STQSSRIPAAAAPTRARVPGGALPEALVEPFSQVAHHAAGFLDALRAIAKALRSEMRDKP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DEARRLSTLYAQIGALAPRLEGVHDTAQLLLQDAPEGAVPAAKWFTLAVDGDFIVVKAHA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECC
SPVLPGNTLRNHLWSAVRGAVLTSATLTSCGQFDFFLREAGLHGDDAVTTLEVPSPFDYA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCCHH
LQGTLVATETQADPRQAADYTAEMVDALLSDLAMVEAGALVLFTSRDQMRQAVDALPTAM
HCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHH
RSTVLVQTQMPRSQLLARHRERVAAGEPSIIFGMQSFGEGLDLPGALCESLFITKLPFAP
HHHEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHCCCCCC
PDDPVGEARAEWLRGTGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDRRLVRT
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
AYGQRLLKGLPPFTLQRRTAA
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SQQEWAAQALQSFDAVVQATEGLRSRGGQRRMAEQVAHTFARAQLGKVEAEDGDSAPAP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PARSIAVVQAGTGVGKSLAYSVPAIAMALARGTRVLISTATVALQEQLVQKDLPALAARM
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHC
PQPFQFALAKGRGRYVCKLKLERLAGTGEAGDEGPEDDLFAEEEAAARAARPRHETEARM
CCCHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
KFYATMADVLARGAWDGDRDTLESPPEPEVWSPVAAEASSCTGKHCPAFGQCTYYDRRKA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH
LVAAQVIVANHDLLLSSIGARLLPELDNCLLVVDEAHHLPSTALDQFACEADLSRLNWID
HHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
KLASRALRIGTLMEVEEVADIPNHSARLRAALQDAARMVMDVYGDELRAPRPAWGGGRTA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STQSSRIPAAAAPTRARVPGGALPEALVEPFSQVAHHAAGFLDALRAIAKALRSEMRDKP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DEARRLSTLYAQIGALAPRLEGVHDTAQLLLQDAPEGAVPAAKWFTLAVDGDFIVVKAHA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECC
SPVLPGNTLRNHLWSAVRGAVLTSATLTSCGQFDFFLREAGLHGDDAVTTLEVPSPFDYA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCCCHH
LQGTLVATETQADPRQAADYTAEMVDALLSDLAMVEAGALVLFTSRDQMRQAVDALPTAM
HCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHH
RSTVLVQTQMPRSQLLARHRERVAAGEPSIIFGMQSFGEGLDLPGALCESLFITKLPFAP
HHHEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHCCCCCC
PDDPVGEARAEWLRGTGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDRRLVRT
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
AYGQRLLKGLPPFTLQRRTAA
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8396546; 8385320 [H]