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The map label for this gene is ychM [C]

Identifier: 119947307

GI number: 119947307

Start: 4521951

End: 4523681

Strand: Direct

Name: ychM [C]

Synonym: Ping_3713

Alternate gene names: 119947307

Gene position: 4521951-4523681 (Clockwise)

Preceding gene: 119947306

Following gene: 119947308

Centisome position: 99.17

GC content: 44.31

Gene sequence:

>1731_bases
ATGCCCGGGTTAGAAGGTCTGCTGAATTACCAACGGCAATGGTTTCGTGATGATATCCGTGCTGCGTTATCTGTGGTGGC
CGTTGCCCTGCCAGTTGCTATTGCCTATGCCCAATTGACCGGTGTTAATGCGGTAGTGGGGTTGTATTCCTGTATTCTAC
CAATGTTGGTTTATGCGCTATTTGGTACTTCACGGCAATTAATAGTGGGTCCCGATGCGGCAACCTGTGCGGTCATTGCA
GCAGTTGTAACCCCGTTAGCCGCTGGGGATCCGGTTAAACATTGGCAACTGGTTATGACCATGACCGGGATGACCGGTAT
TTGGTGTTTGCTTGCCAGTAGATTTAAGCTTGGAGTACTGGCTGACTTTCTGTCCAAACCGATTTTAATGGGGCTGTTAA
ATGGTGTTGCAATCACCATTATTGTCGGTCAATTTTCTAAAGTTTTTGGCTTTAAATTCGAACATCCTTATCTGATTGAA
CGCCTCGCTGACTTGCCCCGTTATATTACCCAATTTCATAGACCAACAATATTAATAAGCTTAGTGGCCCTATTTGTCTT
TTTGTTAATTAAACGTTTTCGTCCTCAGTGGCCTGCCGCATTAGCGGTGATGATAATCAGCGCTTTTGCGGTCTGGTTTT
TTAACTTGGGTACCTTTGAAATTAAAACAGTCGGGGCGATTCAATCTGGACTACCGATATTTCAGACACCGGCCTTTGAT
CTTGGTATAGCACGTGAACTGGTGATGCCGGCACTTAATCTGGCGATGGTAAGTTTTGTCAGTATGATGCTGACGGCACG
CAGTTTTGCAGCCAAAAATGGTTATGATATTGATGCTGATAAAGAGTTTATGGCTTTGGGTCTGGCTAATATCGCTTCCG
CATTCTCCCAGGGGTTTGCCGTCAGTGGTGCTGATTCGCGCACCGCCGTTAATGATGCCAATGGCGGGAAAACGCAGTGG
GTCTCTATTATAGCGGCTTTATTAATTACTCTGATCGCATTATTTTTGACTGCGCCATTACAATATATCCCTTCGGCAGC
ATTGGGTATTGTGCTGGTTATTGCATCCTTATCGCTGATTGATCTAAAGGCGCTGTGGCAGCTGCGCAAACGGGATAATT
CGGCTTTTTTTCTGGCGTTCACAACCTTATTAGCAGTGCTCTTTATTGGTGTTATTCCCGGGATCACTCTGGCAGTACTG
TTAGGTTTATTTCAATTCTTACGCGTTGTAATGCGCCCCACGGAGCAAGTGTTAGGTCTTGATCATAAAGGGGTCATACG
CAGCATAGATAGTGCGAAAAAAGCTATACCTATACATGGTGTATTTATTTATCGCTTTAATTCACCGCTGACCTATTTTA
ATGCGCTGTACTTTAAACGCCAGCTGCTTAGGAAGATAGCAGCTGAAGAAGGTGTTGAGTGTCTGATTATTGATGCAGTG
CCCTGTTTTACGCACTTAGATTTGAGTGTAATGGCCATGCTTGCAGATTTGCATATTATATTAAAAAAACTCGGTATTCG
CCTGGTGGTAGCGGGACGCAAGCGGCAAATGCTCAAGTGGTGTGAGTTAGCCAGTGTATCAACCACCGATGGCGGGGTAT
TGATACGTTCAGATCTTTATTTAGCATTAAAAATGAATCAAATCTATAAACAAGCACTCGCGGAGGGATTAGCACCTTTA
GTCCATAAACAACCCAACAATGAAGATGTCTTAATACACAGTCATTTATAG

Upstream 100 bases:

>100_bases
GTTTTTCTTTTATATCGGGCATAATATTGGGCACTTTCCGATTTTTAATTCTCCACAGATAAAGAGGTCCCCCTTGAAGT
TTGCTCGCTTGTATTCGTTT

Downstream 100 bases:

>100_bases
GGATATTAAGGTCTTTATTTTGGAAGATGAATAATCAAAGTGATGGTATAATATGCTGTTTTAAAATGTGTTTCATTTTA
ATAAACCGTCTGTCTGATGA

Product: sulphate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MPGLEGLLNYQRQWFRDDIRAALSVVAVALPVAIAYAQLTGVNAVVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIA
AVVTPLAAGDPVKHWQLVMTMTGMTGIWCLLASRFKLGVLADFLSKPILMGLLNGVAITIIVGQFSKVFGFKFEHPYLIE
RLADLPRYITQFHRPTILISLVALFVFLLIKRFRPQWPAALAVMIISAFAVWFFNLGTFEIKTVGAIQSGLPIFQTPAFD
LGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFMALGLANIASAFSQGFAVSGADSRTAVNDANGGKTQW
VSIIAALLITLIALFLTAPLQYIPSAALGIVLVIASLSLIDLKALWQLRKRDNSAFFLAFTTLLAVLFIGVIPGITLAVL
LGLFQFLRVVMRPTEQVLGLDHKGVIRSIDSAKKAIPIHGVFIYRFNSPLTYFNALYFKRQLLRKIAAEEGVECLIIDAV
PCFTHLDLSVMAMLADLHIILKKLGIRLVVAGRKRQMLKWCELASVSTTDGGVLIRSDLYLALKMNQIYKQALAEGLAPL
VHKQPNNEDVLIHSHL

Sequences:

>Translated_576_residues
MPGLEGLLNYQRQWFRDDIRAALSVVAVALPVAIAYAQLTGVNAVVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIA
AVVTPLAAGDPVKHWQLVMTMTGMTGIWCLLASRFKLGVLADFLSKPILMGLLNGVAITIIVGQFSKVFGFKFEHPYLIE
RLADLPRYITQFHRPTILISLVALFVFLLIKRFRPQWPAALAVMIISAFAVWFFNLGTFEIKTVGAIQSGLPIFQTPAFD
LGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFMALGLANIASAFSQGFAVSGADSRTAVNDANGGKTQW
VSIIAALLITLIALFLTAPLQYIPSAALGIVLVIASLSLIDLKALWQLRKRDNSAFFLAFTTLLAVLFIGVIPGITLAVL
LGLFQFLRVVMRPTEQVLGLDHKGVIRSIDSAKKAIPIHGVFIYRFNSPLTYFNALYFKRQLLRKIAAEEGVECLIIDAV
PCFTHLDLSVMAMLADLHIILKKLGIRLVVAGRKRQMLKWCELASVSTTDGGVLIRSDLYLALKMNQIYKQALAEGLAPL
VHKQPNNEDVLIHSHL
>Mature_575_residues
PGLEGLLNYQRQWFRDDIRAALSVVAVALPVAIAYAQLTGVNAVVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIAA
VVTPLAAGDPVKHWQLVMTMTGMTGIWCLLASRFKLGVLADFLSKPILMGLLNGVAITIIVGQFSKVFGFKFEHPYLIER
LADLPRYITQFHRPTILISLVALFVFLLIKRFRPQWPAALAVMIISAFAVWFFNLGTFEIKTVGAIQSGLPIFQTPAFDL
GIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFMALGLANIASAFSQGFAVSGADSRTAVNDANGGKTQWV
SIIAALLITLIALFLTAPLQYIPSAALGIVLVIASLSLIDLKALWQLRKRDNSAFFLAFTTLLAVLFIGVIPGITLAVLL
GLFQFLRVVMRPTEQVLGLDHKGVIRSIDSAKKAIPIHGVFIYRFNSPLTYFNALYFKRQLLRKIAAEEGVECLIIDAVP
CFTHLDLSVMAMLADLHIILKKLGIRLVVAGRKRQMLKWCELASVSTTDGGVLIRSDLYLALKMNQIYKQALAEGLAPLV
HKQPNNEDVLIHSHL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=497, Percent_Identity=26.5593561368209, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI39752683, Length=497, Percent_Identity=26.5593561368209, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI269784651, Length=493, Percent_Identity=25.7606490872211, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI94721259, Length=493, Percent_Identity=26.369168356998, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI94721255, Length=493, Percent_Identity=26.369168356998, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI94721253, Length=493, Percent_Identity=26.369168356998, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI94721257, Length=493, Percent_Identity=26.369168356998, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI262206105, Length=559, Percent_Identity=25.9391771019678, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI262206075, Length=559, Percent_Identity=25.9391771019678, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI262206069, Length=559, Percent_Identity=25.9391771019678, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI262206063, Length=559, Percent_Identity=25.9391771019678, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4505697, Length=509, Percent_Identity=26.7190569744597, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI45827802, Length=436, Percent_Identity=26.605504587156, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4557535, Length=509, Percent_Identity=25.7367387033399, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI47131207, Length=510, Percent_Identity=25.8823529411765, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI20336272, Length=510, Percent_Identity=25.8823529411765, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI16418413, Length=507, Percent_Identity=23.0769230769231, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI217272867, Length=507, Percent_Identity=23.0769230769231, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI100913030, Length=516, Percent_Identity=25.1937984496124, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI20336282, Length=494, Percent_Identity=24.8987854251012, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI16306483, Length=497, Percent_Identity=25.5533199195171, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI16418457, Length=505, Percent_Identity=24.950495049505, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI301601599, Length=505, Percent_Identity=24.950495049505, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI301601602, Length=241, Percent_Identity=27.8008298755187, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI65506789, Length=382, Percent_Identity=25.9162303664921, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI87081859, Length=434, Percent_Identity=23.0414746543779, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551690, Length=542, Percent_Identity=25.4612546125461, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI86565215, Length=514, Percent_Identity=25.875486381323, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17566848, Length=615, Percent_Identity=24.2276422764228, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI86564196, Length=492, Percent_Identity=25.8130081300813, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17562578, Length=496, Percent_Identity=26.008064516129, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193203292, Length=513, Percent_Identity=24.5614035087719, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI86564876, Length=388, Percent_Identity=23.9690721649485, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI86565209, Length=231, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI86565211, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325260, Length=512, Percent_Identity=23.6328125, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6323121, Length=469, Percent_Identity=25.1599147121535, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319771, Length=465, Percent_Identity=23.2258064516129, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI85815873, Length=437, Percent_Identity=27.0022883295195, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21358229, Length=463, Percent_Identity=26.5658747300216, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI19922482, Length=525, Percent_Identity=24.952380952381, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24649801, Length=454, Percent_Identity=27.3127753303965, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24666186, Length=546, Percent_Identity=22.5274725274725, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21355087, Length=466, Percent_Identity=25.9656652360515, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24647160, Length=465, Percent_Identity=26.0215053763441, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24651449, Length=480, Percent_Identity=24.5833333333333, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI21358633, Length=503, Percent_Identity=23.4592445328032, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24663084, Length=526, Percent_Identity=24.7148288973384, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21357695, Length=526, Percent_Identity=24.7148288973384, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 63017; Mature: 62886

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
>Mature Secondary Structure 
PGLEGLLNYQRQWFRDDIRAALSVVAVALPVAIAYAQLTGVNAVVGLYSCILPMLVYAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGTSRQLIVGPDAATCAVIAAVVTPLAAGDPVKHWQLVMTMTGMTGIWCLLASRFKLGVL
HCCCCEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADFLSKPILMGLLNGVAITIIVGQFSKVFGFKFEHPYLIERLADLPRYITQFHRPTILIS
HHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
LVALFVFLLIKRFRPQWPAALAVMIISAFAVWFFNLGTFEIKTVGAIQSGLPIFQTPAFD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCCCHH
LGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFMALGLANIASAFSQGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
VSGADSRTAVNDANGGKTQWVSIIAALLITLIALFLTAPLQYIPSAALGIVLVIASLSLI
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
DLKALWQLRKRDNSAFFLAFTTLLAVLFIGVIPGITLAVLLGLFQFLRVVMRPTEQVLGL
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
DHKGVIRSIDSAKKAIPIHGVFIYRFNSPLTYFNALYFKRQLLRKIAAEEGVECLIIDAV
CCHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
PCFTHLDLSVMAMLADLHIILKKLGIRLVVAGRKRQMLKWCELASVSTTDGGVLIRSDLY
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCEEEECCEE
LALKMNQIYKQALAEGLAPLVHKQPNNEDVLIHSHL
EEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]