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The map label for this gene is abcA [H]

Identifier: 119947062

GI number: 119947062

Start: 4281176

End: 4282498

Strand: Reverse

Name: abcA [H]

Synonym: Ping_3460

Alternate gene names: 119947062

Gene position: 4282498-4281176 (Counterclockwise)

Preceding gene: 119947063

Following gene: 119947061

Centisome position: 93.92

GC content: 32.35

Gene sequence:

>1323_bases
ATGTATTGTAATGAAACAATATTATCAGTGGATAATGTGAGTAAATGTTTTGAGATGTACAAGAAACCTTCTCATCGGTT
ATTACAAATGTTCTTAAGGCGTAAAAAACTCTATAAAGAATTCTGGGCATTAAAAAATATATCATTTAGCGTTTCTCGTG
GAGAGTCTTTAGGTATTATTGGCCGCAATGGTGCTGGTAAATCTACTTTATTACAAATAATTTGTGATACGTTGACACCC
ACTACTGGTGAAATAAAAGTCAACGGAAGGGTTGCCGCTTTACTTGAGCTTGGGGCAGGATTTAATCCTGAATTTACTGG
TAAGGATAATGTATATCTATGTGCATCTTTATATGGGATGTCAAATGATGAAATTGATGAACAATATGAAAATATTATTC
AATTTGCAGATATAGGTGAATTTATAAATCAAGTAGTAAAAACATACTCAAGTGGTATGTATGTTCGTTTAGCCTTTGCT
GTTATCGCCCATGTCAATGCAGATATGCTTATTATTGATGAAGCTTTAGCTGTTGGTGATGCTTTATTTACTCAAAAATG
TATGCGGTTTTTACGAGAGTTTAAAAAAACTGGAGTACTATTATTCGTTAGTCATGATACCTCGGCAGTTACAAATTTAT
GCGATAAAGCTGTTTGGTTGAAAAATGGTCAGTTGGAAAGCTTTGGTTCTGCAAAAGATGTCTCAGAGCAATATATGGCT
TTTCTATATCAATCAAAAATATCGTCTAAAGATAAAGAACCTAAAAAAGTACTGAAACAAAATAAAGCATTTAAAGATTT
CCGTCTTGACTTTATTAATTCAACAAATATTAGAAATGATATAAAAGTAATACAATTTGATGAATTAAATGTGAAATCTT
TTGGCCATGATGGAGCTAATTTTACAGATGTATATATAACCGATACGGATAATAATCCGTTAAGTTGGTTTGTTGGAGGG
GAAGATGTACGATTGAAATTAGTTGTGGATGTTTTATCTGAGCTAAAAAATCCCATAATTGGTTTTACAGTTAAAGATAA
GCTTGGTCAGCCTATATTTGGTGATAACACATATATATCTACATTAAATCATAATTTTTTGTGCGATGCGAATAATGTAT
TAAATGTTGAATTTAGTTTTCTAATGCCAATCTTGATGAATGGTGATTATTCATTATCTGTTGCCATCGCGGATGGTGAC
CAAGAAAGTCATGTTCAGCATCAATGGATAAATGATGCGTTGGTATTCAGATCCATGTCCACGTCTGCTAGCACTGGTTT
AGTAGGTATTCCGATGAAAGACATCAAATTTACAGTAAAATAG

Upstream 100 bases:

>100_bases
TCTATAACTTTAAATGGTTACGCAATCTATTTTTTTTCTTCAGCATTTATTTATTTATTGGGTTTTTTGTGGTTTCAAAA
ATTGAGAAAAGGTTTTAGCG

Downstream 100 bases:

>100_bases
GCGGGTATTGTGTCTCATATAGAACAGCAAGAGTTTTGTCAATCAGTTAGATTAAAGTTTTCTTCATTTTTTGAGTATAA
ATTTGTGCTTGATATTGGGT

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; arabinose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MYCNETILSVDNVSKCFEMYKKPSHRLLQMFLRRKKLYKEFWALKNISFSVSRGESLGIIGRNGAGKSTLLQIICDTLTP
TTGEIKVNGRVAALLELGAGFNPEFTGKDNVYLCASLYGMSNDEIDEQYENIIQFADIGEFINQVVKTYSSGMYVRLAFA
VIAHVNADMLIIDEALAVGDALFTQKCMRFLREFKKTGVLLFVSHDTSAVTNLCDKAVWLKNGQLESFGSAKDVSEQYMA
FLYQSKISSKDKEPKKVLKQNKAFKDFRLDFINSTNIRNDIKVIQFDELNVKSFGHDGANFTDVYITDTDNNPLSWFVGG
EDVRLKLVVDVLSELKNPIIGFTVKDKLGQPIFGDNTYISTLNHNFLCDANNVLNVEFSFLMPILMNGDYSLSVAIADGD
QESHVQHQWINDALVFRSMSTSASTGLVGIPMKDIKFTVK

Sequences:

>Translated_440_residues
MYCNETILSVDNVSKCFEMYKKPSHRLLQMFLRRKKLYKEFWALKNISFSVSRGESLGIIGRNGAGKSTLLQIICDTLTP
TTGEIKVNGRVAALLELGAGFNPEFTGKDNVYLCASLYGMSNDEIDEQYENIIQFADIGEFINQVVKTYSSGMYVRLAFA
VIAHVNADMLIIDEALAVGDALFTQKCMRFLREFKKTGVLLFVSHDTSAVTNLCDKAVWLKNGQLESFGSAKDVSEQYMA
FLYQSKISSKDKEPKKVLKQNKAFKDFRLDFINSTNIRNDIKVIQFDELNVKSFGHDGANFTDVYITDTDNNPLSWFVGG
EDVRLKLVVDVLSELKNPIIGFTVKDKLGQPIFGDNTYISTLNHNFLCDANNVLNVEFSFLMPILMNGDYSLSVAIADGD
QESHVQHQWINDALVFRSMSTSASTGLVGIPMKDIKFTVK
>Mature_440_residues
MYCNETILSVDNVSKCFEMYKKPSHRLLQMFLRRKKLYKEFWALKNISFSVSRGESLGIIGRNGAGKSTLLQIICDTLTP
TTGEIKVNGRVAALLELGAGFNPEFTGKDNVYLCASLYGMSNDEIDEQYENIIQFADIGEFINQVVKTYSSGMYVRLAFA
VIAHVNADMLIIDEALAVGDALFTQKCMRFLREFKKTGVLLFVSHDTSAVTNLCDKAVWLKNGQLESFGSAKDVSEQYMA
FLYQSKISSKDKEPKKVLKQNKAFKDFRLDFINSTNIRNDIKVIQFDELNVKSFGHDGANFTDVYITDTDNNPLSWFVGG
EDVRLKLVVDVLSELKNPIIGFTVKDKLGQPIFGDNTYISTLNHNFLCDANNVLNVEFSFLMPILMNGDYSLSVAIADGD
QESHVQHQWINDALVFRSMSTSASTGLVGIPMKDIKFTVK

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=242, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI27477115, Length=220, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI27436953, Length=210, Percent_Identity=27.6190476190476, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI27262624, Length=222, Percent_Identity=26.5765765765766, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI27262626, Length=222, Percent_Identity=26.5765765765766, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI6005701, Length=206, Percent_Identity=26.6990291262136, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI31657092, Length=220, Percent_Identity=22.2727272727273, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI30795238, Length=228, Percent_Identity=21.0526315789474, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI27881501, Length=228, Percent_Identity=21.0526315789474, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI116734710, Length=240, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788210, Length=288, Percent_Identity=26.3888888888889, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789032, Length=249, Percent_Identity=21.285140562249, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789751, Length=226, Percent_Identity=26.5486725663717, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786398, Length=318, Percent_Identity=24.2138364779874, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081782, Length=236, Percent_Identity=23.728813559322, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081709, Length=222, Percent_Identity=22.5225225225225, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790467, Length=206, Percent_Identity=25.2427184466019, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994943, Length=246, Percent_Identity=23.1707317073171, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787112, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786981, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI48995001, Length=228, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87081834, Length=200, Percent_Identity=26.5, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786319, Length=225, Percent_Identity=25.7777777777778, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786653, Length=235, Percent_Identity=24.6808510638298, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=241, Percent_Identity=24.896265560166, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71983516, Length=214, Percent_Identity=25.7009345794392, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983510, Length=214, Percent_Identity=25.7009345794392, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=214, Percent_Identity=25.7009345794392, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17510237, Length=245, Percent_Identity=23.265306122449, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=219, Percent_Identity=23.7442922374429, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323959, Length=204, Percent_Identity=25.9803921568627, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643672, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007184, Length=202, Percent_Identity=22.7722772277228, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221500365, Length=202, Percent_Identity=22.7722772277228, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=213, Percent_Identity=23.943661971831, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573571, Length=228, Percent_Identity=22.8070175438596, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28573573, Length=228, Percent_Identity=22.8070175438596, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648314, Length=200, Percent_Identity=23.5, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 49399; Mature: 49399

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCNETILSVDNVSKCFEMYKKPSHRLLQMFLRRKKLYKEFWALKNISFSVSRGESLGII
CCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEE
GRNGAGKSTLLQIICDTLTPTTGEIKVNGRVAALLELGAGFNPEFTGKDNVYLCASLYGM
ECCCCCHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCCCCCCCCCEEEEEEECCC
SNDEIDEQYENIIQFADIGEFINQVVKTYSSGMYVRLAFAVIAHVNADMLIIDEALAVGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHH
ALFTQKCMRFLREFKKTGVLLFVSHDTSAVTNLCDKAVWLKNGQLESFGSAKDVSEQYMA
HHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHH
FLYQSKISSKDKEPKKVLKQNKAFKDFRLDFINSTNIRNDIKVIQFDELNVKSFGHDGAN
HHHHHHHCCCCCCHHHHHHHCCCCHHHEEEEECCCCCCCCCEEEEEECCCHHHCCCCCCC
FTDVYITDTDNNPLSWFVGGEDVRLKLVVDVLSELKNPIIGFTVKDKLGQPIFGDNTYIS
EEEEEEEECCCCCEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCEEE
TLNHNFLCDANNVLNVEFSFLMPILMNGDYSLSVAIADGDQESHVQHQWINDALVFRSMS
ECCCCEEECCCCEEEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEECC
TSASTGLVGIPMKDIKFTVK
CCCCCCEEECCHHHCEEEEC
>Mature Secondary Structure
MYCNETILSVDNVSKCFEMYKKPSHRLLQMFLRRKKLYKEFWALKNISFSVSRGESLGII
CCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEE
GRNGAGKSTLLQIICDTLTPTTGEIKVNGRVAALLELGAGFNPEFTGKDNVYLCASLYGM
ECCCCCHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCCCCCCCCCEEEEEEECCC
SNDEIDEQYENIIQFADIGEFINQVVKTYSSGMYVRLAFAVIAHVNADMLIIDEALAVGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHH
ALFTQKCMRFLREFKKTGVLLFVSHDTSAVTNLCDKAVWLKNGQLESFGSAKDVSEQYMA
HHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHH
FLYQSKISSKDKEPKKVLKQNKAFKDFRLDFINSTNIRNDIKVIQFDELNVKSFGHDGAN
HHHHHHHCCCCCCHHHHHHHCCCCHHHEEEEECCCCCCCCCEEEEEECCCHHHCCCCCCC
FTDVYITDTDNNPLSWFVGGEDVRLKLVVDVLSELKNPIIGFTVKDKLGQPIFGDNTYIS
EEEEEEEECCCCCEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCEEE
TLNHNFLCDANNVLNVEFSFLMPILMNGDYSLSVAIADGDQESHVQHQWINDALVFRSMS
ECCCCEEECCCCEEEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEECC
TSASTGLVGIPMKDIKFTVK
CCCCCCEEECCHHHCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arabinose [Periplasm]; H2O [C]

Specific reaction: ATP + arabinose [Periplasm] + H2O = ADP + phosphate + arabinose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]