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The map label for this gene is rihA [H]

Identifier: 119945596

GI number: 119945596

Start: 2319271

End: 2321514

Strand: Reverse

Name: rihA [H]

Synonym: Ping_1902

Alternate gene names: 119945596

Gene position: 2321514-2319271 (Counterclockwise)

Preceding gene: 119945600

Following gene: 119945595

Centisome position: 50.91

GC content: 37.66

Gene sequence:

>2244_bases
ATGAGAAAAATAGGACAAATAAAAAACTTAATTATTGATACTGATATGGGGTGGGATGATGTACTAGCTATCTTGCTGTT
AATCAAAAATCCTAATTATAATATTTTGGGCATTACGGTTACCGGTTGTGGCGAAACTCACTTAGAGCAAGGCGTCGAAT
TAGCATTACAACTTGTTACTTTAGGCAATCAGCCTGATATCTGTGTTTGTGCCGGAGCTGATAAAACAGGGCAATATAAC
CACCAATTCCCAGAATCTTTTAGGGATATGATGGATGATGCTTGTGGTTTAAGAGATAAACTACCTGCGGCAGAGAGCAC
AAAGGATCAACGTAATGCATGGGAATTTATCAACGATTGCTTAAACGAGCAAGAAAACCAAATCACTATTTTATCATTAG
GTGGTTTAACGAATATTCAAAAATTAATAGAAATGCAACCTTTCCCTGCGCTTGAAAATATAGAACGTATTGTTGTTATG
GGAGGTGCTATTGACGTTGATGGCAACGTGGCCGCGCTAAATAATTCAAATAAATATTGGGATCAGGGAACAGAATACGC
TTCAAATACTTATGCTGAATGGAATATTTTTTTAGATCCGAAAGCTGCTCAAGTTACTTTTAATTCCGGCATTCCTATTA
AATTAGTCCCTTTAGATGCATGTGATTACGCTATTTTAGATAAAACATACTACCAATTGGTCACCGCAAAAGATGCTGTT
GCAAACTTTGTCAGAGCGCTTTTATACCAAAAAACCGAGGGCTCAGCCCAAGAGAATATTCCTTTGCCTGTCTTCGATCC
TTTAGCGGCAATAGAAATGACCAATGATTTAGTAAAATCAAAATATGAAAAAATGCGTATAGGTGTTAAAACAACTGAAA
CAAAAAAAGATAATACCTGTGGGCAAACCTATATTACAACTAATAAATCTGTACCCGAAATTGAAGTTGTCACCAAAATA
TCAGCAAATGAATTTAAACAAAGATTTCAAGAATCTGTCAACTCGCCTCTGTGTCCGCGATTAAATGAAAACATAAGTAA
AAATATCGCTATTTTGATATACGATCAGATCGAAATTCAAGATTTCGCTGGTGCTTTTGAAATTTTTTCAGCAGCTCGTA
ATGATGATAATTCATCGGTGTTTAATGTTTTTACTGTGGCAGCAGATAAGGCACCGATAACCTGTAATTCAGGTGTTACA
CCCACAGGCGGAAAAAGTAGTTCCTTTAAAATAACAGCAGATCACACTTTAGATTGTCACCCGAAAATTGATACCTTATA
TATTATTGGCGGCCCAGGCATTGACGCTTTACTTGATAAAGAAGCGCAACAACCCTTCCTGACAGAATGGATTTCTATAG
TATCTGAGGAAGCTGATTATGTTGCAGGGACTTGTTCCGGCGCATTACTCCTAGTGCTTTCTAAACAATTAAAAAATATG
AATGTGACAACTCATCATACCCGTTTTGAGCAAATGGACGCGTTAAGTGAAAAGTACAGTTTAGGCCTTAACGTTTTAGA
TACACGTAATGGCGAGCAGTACATTCATAACCCCAGATCCAAATTTATGACTTCAGGTGGGGTCACATGTGGTCTTGCAC
TTTCTCTTCATATTGTTGAGTTATACCAAGGTTTAGCAAGAAAAGAGTCGCTAGCAAAAGATGTTCTGGAATATACCATT
CCCAGAGGTGTTGCACATCCTGAATCTTATAGCGCATCACATATGGATCCTGCTCATTTTGTGCTTGGTTTTTCACATCT
GAATATTATTGTTTCAGACTTAGCGATGATGGATGATGCAACTCGATTTTATAAAAGAACCTTAGGTTTTAGAGAGGCGT
GGAGTGTTTGGTTGTCACCGGAATCTTGTGAGCACTTTGCGAGAGATGCGGGTTTTGCCGATGGCAAAGGAAAAGTAATG
GTTCGTTTTCTGATCCATCCTAATGCTCAATTTCATTTAGAGTTAATGTATTATGAATACCCTAAAGGAAACCAGAAAAT
AAGCTTCCATAAAACAAATGATGTAGGTGGCATTAGGCATGTGGCATTAGAAGTAAATAATATTCTGGAAGTGTATGACT
GGTTAAAAAATCAGGAAGGAGTCAAAATGTTATCGGACACACCTCCTGAAAAATTAACACCTGATCCTCAAACATTTTTC
TATTGGATTGATCCCTATGGAGTGCAATGGGAAATGGAAGAAGGGAGACCCATGGCCAGAGTTATTAATGGCACTGTCGG
CTAA

Upstream 100 bases:

>100_bases
AGCACCCCAAAAAACGTTATTTTTGACATATATAAATTCCACTTCAACTATTTTTAACATCGCTGATATTGCTCAGTTAA
ATCATAAAAGGGAGCGTAAA

Downstream 100 bases:

>100_bases
TTTACTGTGCAGCTGTAAATAACTAAAAGAATAATATTTATATTAAAAAAGGGTAATAACATTATCTGTTATTACCCTTT
TTCTTACCTTATTTTCACTT

Product: inosine/uridine-preferring nucleoside hydrolase

Products: uracil; ribose; cytosine [C]

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MRKIGQIKNLIIDTDMGWDDVLAILLLIKNPNYNILGITVTGCGETHLEQGVELALQLVTLGNQPDICVCAGADKTGQYN
HQFPESFRDMMDDACGLRDKLPAAESTKDQRNAWEFINDCLNEQENQITILSLGGLTNIQKLIEMQPFPALENIERIVVM
GGAIDVDGNVAALNNSNKYWDQGTEYASNTYAEWNIFLDPKAAQVTFNSGIPIKLVPLDACDYAILDKTYYQLVTAKDAV
ANFVRALLYQKTEGSAQENIPLPVFDPLAAIEMTNDLVKSKYEKMRIGVKTTETKKDNTCGQTYITTNKSVPEIEVVTKI
SANEFKQRFQESVNSPLCPRLNENISKNIAILIYDQIEIQDFAGAFEIFSAARNDDNSSVFNVFTVAADKAPITCNSGVT
PTGGKSSSFKITADHTLDCHPKIDTLYIIGGPGIDALLDKEAQQPFLTEWISIVSEEADYVAGTCSGALLLVLSKQLKNM
NVTTHHTRFEQMDALSEKYSLGLNVLDTRNGEQYIHNPRSKFMTSGGVTCGLALSLHIVELYQGLARKESLAKDVLEYTI
PRGVAHPESYSASHMDPAHFVLGFSHLNIIVSDLAMMDDATRFYKRTLGFREAWSVWLSPESCEHFARDAGFADGKGKVM
VRFLIHPNAQFHLELMYYEYPKGNQKISFHKTNDVGGIRHVALEVNNILEVYDWLKNQEGVKMLSDTPPEKLTPDPQTFF
YWIDPYGVQWEMEEGRPMARVINGTVG

Sequences:

>Translated_747_residues
MRKIGQIKNLIIDTDMGWDDVLAILLLIKNPNYNILGITVTGCGETHLEQGVELALQLVTLGNQPDICVCAGADKTGQYN
HQFPESFRDMMDDACGLRDKLPAAESTKDQRNAWEFINDCLNEQENQITILSLGGLTNIQKLIEMQPFPALENIERIVVM
GGAIDVDGNVAALNNSNKYWDQGTEYASNTYAEWNIFLDPKAAQVTFNSGIPIKLVPLDACDYAILDKTYYQLVTAKDAV
ANFVRALLYQKTEGSAQENIPLPVFDPLAAIEMTNDLVKSKYEKMRIGVKTTETKKDNTCGQTYITTNKSVPEIEVVTKI
SANEFKQRFQESVNSPLCPRLNENISKNIAILIYDQIEIQDFAGAFEIFSAARNDDNSSVFNVFTVAADKAPITCNSGVT
PTGGKSSSFKITADHTLDCHPKIDTLYIIGGPGIDALLDKEAQQPFLTEWISIVSEEADYVAGTCSGALLLVLSKQLKNM
NVTTHHTRFEQMDALSEKYSLGLNVLDTRNGEQYIHNPRSKFMTSGGVTCGLALSLHIVELYQGLARKESLAKDVLEYTI
PRGVAHPESYSASHMDPAHFVLGFSHLNIIVSDLAMMDDATRFYKRTLGFREAWSVWLSPESCEHFARDAGFADGKGKVM
VRFLIHPNAQFHLELMYYEYPKGNQKISFHKTNDVGGIRHVALEVNNILEVYDWLKNQEGVKMLSDTPPEKLTPDPQTFF
YWIDPYGVQWEMEEGRPMARVINGTVG
>Mature_747_residues
MRKIGQIKNLIIDTDMGWDDVLAILLLIKNPNYNILGITVTGCGETHLEQGVELALQLVTLGNQPDICVCAGADKTGQYN
HQFPESFRDMMDDACGLRDKLPAAESTKDQRNAWEFINDCLNEQENQITILSLGGLTNIQKLIEMQPFPALENIERIVVM
GGAIDVDGNVAALNNSNKYWDQGTEYASNTYAEWNIFLDPKAAQVTFNSGIPIKLVPLDACDYAILDKTYYQLVTAKDAV
ANFVRALLYQKTEGSAQENIPLPVFDPLAAIEMTNDLVKSKYEKMRIGVKTTETKKDNTCGQTYITTNKSVPEIEVVTKI
SANEFKQRFQESVNSPLCPRLNENISKNIAILIYDQIEIQDFAGAFEIFSAARNDDNSSVFNVFTVAADKAPITCNSGVT
PTGGKSSSFKITADHTLDCHPKIDTLYIIGGPGIDALLDKEAQQPFLTEWISIVSEEADYVAGTCSGALLLVLSKQLKNM
NVTTHHTRFEQMDALSEKYSLGLNVLDTRNGEQYIHNPRSKFMTSGGVTCGLALSLHIVELYQGLARKESLAKDVLEYTI
PRGVAHPESYSASHMDPAHFVLGFSHLNIIVSDLAMMDDATRFYKRTLGFREAWSVWLSPESCEHFARDAGFADGKGKVM
VRFLIHPNAQFHLELMYYEYPKGNQKISFHKTNDVGGIRHVALEVNNILEVYDWLKNQEGVKMLSDTPPEKLTPDPQTFF
YWIDPYGVQWEMEEGRPMARVINGTVG

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=330, Percent_Identity=28.4848484848485, Blast_Score=83, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: NA

Molecular weight: Translated: 83333; Mature: 83333

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIGQIKNLIIDTDMGWDDVLAILLLIKNPNYNILGITVTGCGETHLEQGVELALQLVT
CCCHHHHHHEEEECCCCHHHHHHHHHEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHEE
LGNQPDICVCAGADKTGQYNHQFPESFRDMMDDACGLRDKLPAAESTKDQRNAWEFINDC
CCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHH
LNEQENQITILSLGGLTNIQKLIEMQPFPALENIERIVVMGGAIDVDGNVAALNNSNKYW
HCCCCCEEEEEEECCHHHHHHHHHCCCCCCHHCCCEEEEECCEEECCCCEEEECCCCCCC
DQGTEYASNTYAEWNIFLDPKAAQVTFNSGIPIKLVPLDACDYAILDKTYYQLVTAKDAV
CCCCCHHCCCEEEEEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
ANFVRALLYQKTEGSAQENIPLPVFDPLAAIEMTNDLVKSKYEKMRIGVKTTETKKDNTC
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCEECCCCCCCCC
GQTYITTNKSVPEIEVVTKISANEFKQRFQESVNSPLCPRLNENISKNIAILIYDQIEIQ
CCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEHH
DFAGAFEIFSAARNDDNSSVFNVFTVAADKAPITCNSGVTPTGGKSSSFKITADHTLDCH
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEECCEEECC
PKIDTLYIIGGPGIDALLDKEAQQPFLTEWISIVSEEADYVAGTCSGALLLVLSKQLKNM
CCCCEEEEEECCCHHHHHCHHCCCHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCC
NVTTHHTRFEQMDALSEKYSLGLNVLDTRNGEQYIHNPRSKFMTSGGVTCGLALSLHIVE
CCEEHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCHHHHEECCCCEEHHHHHHHHHH
LYQGLARKESLAKDVLEYTIPRGVAHPESYSASHMDPAHFVLGFSHLNIIVSDLAMMDDA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRFYKRTLGFREAWSVWLSPESCEHFARDAGFADGKGKVMVRFLIHPNAQFHLELMYYEY
HHHHHHHCCCHHHHEEECCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEEC
PKGNQKISFHKTNDVGGIRHVALEVNNILEVYDWLKNQEGVKMLSDTPPEKLTPDPQTFF
CCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEE
YWIDPYGVQWEMEEGRPMARVINGTVG
EEECCCCEEEECCCCCCHHHHHCCCCC
>Mature Secondary Structure
MRKIGQIKNLIIDTDMGWDDVLAILLLIKNPNYNILGITVTGCGETHLEQGVELALQLVT
CCCHHHHHHEEEECCCCHHHHHHHHHEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHEE
LGNQPDICVCAGADKTGQYNHQFPESFRDMMDDACGLRDKLPAAESTKDQRNAWEFINDC
CCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHH
LNEQENQITILSLGGLTNIQKLIEMQPFPALENIERIVVMGGAIDVDGNVAALNNSNKYW
HCCCCCEEEEEEECCHHHHHHHHHCCCCCCHHCCCEEEEECCEEECCCCEEEECCCCCCC
DQGTEYASNTYAEWNIFLDPKAAQVTFNSGIPIKLVPLDACDYAILDKTYYQLVTAKDAV
CCCCCHHCCCEEEEEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
ANFVRALLYQKTEGSAQENIPLPVFDPLAAIEMTNDLVKSKYEKMRIGVKTTETKKDNTC
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCEECCCCCCCCC
GQTYITTNKSVPEIEVVTKISANEFKQRFQESVNSPLCPRLNENISKNIAILIYDQIEIQ
CCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEHH
DFAGAFEIFSAARNDDNSSVFNVFTVAADKAPITCNSGVTPTGGKSSSFKITADHTLDCH
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEECCEEECC
PKIDTLYIIGGPGIDALLDKEAQQPFLTEWISIVSEEADYVAGTCSGALLLVLSKQLKNM
CCCCEEEEEECCCHHHHHCHHCCCHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCC
NVTTHHTRFEQMDALSEKYSLGLNVLDTRNGEQYIHNPRSKFMTSGGVTCGLALSLHIVE
CCEEHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCHHHHEECCCCEEHHHHHHHHHH
LYQGLARKESLAKDVLEYTIPRGVAHPESYSASHMDPAHFVLGFSHLNIIVSDLAMMDDA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRFYKRTLGFREAWSVWLSPESCEHFARDAGFADGKGKVMVRFLIHPNAQFHLELMYYEY
HHHHHHHCCCHHHHEEECCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEEC
PKGNQKISFHKTNDVGGIRHVALEVNNILEVYDWLKNQEGVKMLSDTPPEKLTPDPQTFF
CCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEE
YWIDPYGVQWEMEEGRPMARVINGTVG
EEECCCCEEEECCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: uridine; H2O; cytidine [C]

Specific reaction: uridine + H2O = uracil + ribose cytidine + H2O = cytosine + ribose [C]

General reaction: Pyrimidine-specific nucleoside hydrolase [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA