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The map label for this gene is yegE [C]

Identifier: 119945531

GI number: 119945531

Start: 2225555

End: 2227519

Strand: Reverse

Name: yegE [C]

Synonym: Ping_1835

Alternate gene names: 119945531

Gene position: 2227519-2225555 (Counterclockwise)

Preceding gene: 119945535

Following gene: 119945530

Centisome position: 48.85

GC content: 37.3

Gene sequence:

>1965_bases
ATGAAGCGTAGTGTTAAAACCGAATTTTTTAAGTTTATCCACAGTACGTTACCCTCTTGGCTTATATTTTCATTAAGTCT
CTGTATTACCTTTATTGCTTGGTCGATCACGACCAAATCTAATCAACTCCATATCCAAGAGCTATTTAAATTTGAGGTGG
CCCAAACTATTCGCTCCATCGAACAGCGTATGCAGGAATATGAGCAAGTATTACGTGGCGGTGTAGGGTTATTTAAATCA
AGTGATCACGTTAATCGCCTCGAATTTCATCATTATATAAGTAATTTACACGTTGAAAAATATTTGACTGGTATTCAAGG
TATTGGCTATGCCGTCATGTTGAAACCAGAAGAAAAAGACACATTTGTTAATATGGTACGACTAGAAGGTTTCAATGATT
TCAGTGTCTTTCCAGAAGGATCTCGTGATAAATACAGTAGCATTCTCTATCTTGAGCCCTTCACGGCCAGAAATCAGCGA
GCGTTTGGATATGATATGTACTCAGAGGAGGCTCGCCATACCGCCATGGACATTGCCCGCGACAATGGTGATATCGCATA
TTCAGCTAAAGTTAAACTGGTTCAGGAAAATGGCGATGATTTACAGAATGGATTTCTCATCTATCTCCCTTTATATCGCA
ATGGTGCTCCTATTGAAAATATTTCTCAGCGTCAAAAAGAACTTATCGGATATGTATATAGCCCATTTCGTATTGATAAT
CTGATTAATGGCATTCTCTTAGGTGATGAAATTCGTCGCATAAACTTTTCAATATATGATGGACATTCAGAAAATGCAAA
TAATCTACTTTACGCTCCCGATAGAATTGGGGCCTATTTGCCTAGTGCTTATAAAAAAGAATCTAAACCTGCTTTTTACG
TTGTTAAGACGATTGAATTTCCAGGCCGAAATTGGACCATTCCCTTTTATAGTACCTCTGTTTTTGAAAAGAGTGTTGAA
AATAACCTAGCTAAATTAGTTGGCATATCAGGCATATTTGTATCGGTACTTTTGCTAATTGTAATGCTGAACATTACAAT
CACCGGGAAAAAATCTATGCAGGCGAAAGCGGAATTAGAAATATTAATTGATCGACTAAAAGCAGCCGCTTCAGCGGGAA
TTGTAGGGATTTGGGATTGGGATGTTGAAAAAAACATTCTGACTTGGGACTCCGTCATGTATAAATTATATGGTTTACAA
AAGTCAGATTTTGAAGATTTGTATGAAGCGTGGATTTCTAGAGTACACATAGATGACCGGATGCATATTGACGGTGAAAT
ACAGGCGGCCCTTAGACATGAACGAGAATATTGTCCTGAGTTTCGAGTTCTGTGGCCAGATAGCTCAGTTCATTATATTA
AAGCGGTATCAAAAACGACATTTGACGAAATAGGCAAGCCAATCCGAATGGTTGGCGTCAATTATGATATTACTGAACAA
AAAAAAATTCAAATGCGCCTTGATAAAGAGGCCTCATATGATCATTTAACGCACCTTCCTAATCGTCGTTTGCTCAATGA
TAGATTAAAGCAAGCGATAGCCTTTTCTAAACGCACTCAAAAAAATCTGGCTATTCTTTTTATTGATTTAGATGGATTTA
AAAGCATAAATGATAGCCATGGACATCAAGTCGGTGATTGGTTATTAACAGAAGTATCCAAACGTATTCAATATTGTTTG
CGCGCTACAGACACAGTTGGACGACTAGGAGGGGATGAGTTTGTAGTTGTACTCCCTGAAATTTATGAGAATGCCAAGGA
GGTAGCTAATAAAATACTAAATAGTTTAGAAGAGCCTTTTGTAATAACAAATAATGGTGTCCTTCATATTTCTTCAAGTA
TTGGAGTGGCAATTTATCCTCTGGATGCAAAAAGCCAAACTATGTTAATGGAGTGCGCTGATAAGGCGATGTATGAGGCA
AAAAAAAGAGGCCGTAATAAAGTTGTTTTTTTTGATGTTGCTTAA

Upstream 100 bases:

>100_bases
CTTACTCCACCAAGGGTTAAGGAGTTCATCGTGCACATTGTGGAAAAAATAGTGAAAGCTTTAATGGTCGGTAAATTGAC
TTTCAGGAGAATGGTTGCAG

Downstream 100 bases:

>100_bases
ATATCGTAATATAGATGGGTGTCTTGATTATGTCTCTTGATAATGATCTTTAACTGACCTAAATAACTCTATCGTTGGTA
CCGGCGAAGAAGGTAATTTT

Product: diguanylate cyclase with PAS/PAC sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MKRSVKTEFFKFIHSTLPSWLIFSLSLCITFIAWSITTKSNQLHIQELFKFEVAQTIRSIEQRMQEYEQVLRGGVGLFKS
SDHVNRLEFHHYISNLHVEKYLTGIQGIGYAVMLKPEEKDTFVNMVRLEGFNDFSVFPEGSRDKYSSILYLEPFTARNQR
AFGYDMYSEEARHTAMDIARDNGDIAYSAKVKLVQENGDDLQNGFLIYLPLYRNGAPIENISQRQKELIGYVYSPFRIDN
LINGILLGDEIRRINFSIYDGHSENANNLLYAPDRIGAYLPSAYKKESKPAFYVVKTIEFPGRNWTIPFYSTSVFEKSVE
NNLAKLVGISGIFVSVLLLIVMLNITITGKKSMQAKAELEILIDRLKAAASAGIVGIWDWDVEKNILTWDSVMYKLYGLQ
KSDFEDLYEAWISRVHIDDRMHIDGEIQAALRHEREYCPEFRVLWPDSSVHYIKAVSKTTFDEIGKPIRMVGVNYDITEQ
KKIQMRLDKEASYDHLTHLPNRRLLNDRLKQAIAFSKRTQKNLAILFIDLDGFKSINDSHGHQVGDWLLTEVSKRIQYCL
RATDTVGRLGGDEFVVVLPEIYENAKEVANKILNSLEEPFVITNNGVLHISSSIGVAIYPLDAKSQTMLMECADKAMYEA
KKRGRNKVVFFDVA

Sequences:

>Translated_654_residues
MKRSVKTEFFKFIHSTLPSWLIFSLSLCITFIAWSITTKSNQLHIQELFKFEVAQTIRSIEQRMQEYEQVLRGGVGLFKS
SDHVNRLEFHHYISNLHVEKYLTGIQGIGYAVMLKPEEKDTFVNMVRLEGFNDFSVFPEGSRDKYSSILYLEPFTARNQR
AFGYDMYSEEARHTAMDIARDNGDIAYSAKVKLVQENGDDLQNGFLIYLPLYRNGAPIENISQRQKELIGYVYSPFRIDN
LINGILLGDEIRRINFSIYDGHSENANNLLYAPDRIGAYLPSAYKKESKPAFYVVKTIEFPGRNWTIPFYSTSVFEKSVE
NNLAKLVGISGIFVSVLLLIVMLNITITGKKSMQAKAELEILIDRLKAAASAGIVGIWDWDVEKNILTWDSVMYKLYGLQ
KSDFEDLYEAWISRVHIDDRMHIDGEIQAALRHEREYCPEFRVLWPDSSVHYIKAVSKTTFDEIGKPIRMVGVNYDITEQ
KKIQMRLDKEASYDHLTHLPNRRLLNDRLKQAIAFSKRTQKNLAILFIDLDGFKSINDSHGHQVGDWLLTEVSKRIQYCL
RATDTVGRLGGDEFVVVLPEIYENAKEVANKILNSLEEPFVITNNGVLHISSSIGVAIYPLDAKSQTMLMECADKAMYEA
KKRGRNKVVFFDVA
>Mature_654_residues
MKRSVKTEFFKFIHSTLPSWLIFSLSLCITFIAWSITTKSNQLHIQELFKFEVAQTIRSIEQRMQEYEQVLRGGVGLFKS
SDHVNRLEFHHYISNLHVEKYLTGIQGIGYAVMLKPEEKDTFVNMVRLEGFNDFSVFPEGSRDKYSSILYLEPFTARNQR
AFGYDMYSEEARHTAMDIARDNGDIAYSAKVKLVQENGDDLQNGFLIYLPLYRNGAPIENISQRQKELIGYVYSPFRIDN
LINGILLGDEIRRINFSIYDGHSENANNLLYAPDRIGAYLPSAYKKESKPAFYVVKTIEFPGRNWTIPFYSTSVFEKSVE
NNLAKLVGISGIFVSVLLLIVMLNITITGKKSMQAKAELEILIDRLKAAASAGIVGIWDWDVEKNILTWDSVMYKLYGLQ
KSDFEDLYEAWISRVHIDDRMHIDGEIQAALRHEREYCPEFRVLWPDSSVHYIKAVSKTTFDEIGKPIRMVGVNYDITEQ
KKIQMRLDKEASYDHLTHLPNRRLLNDRLKQAIAFSKRTQKNLAILFIDLDGFKSINDSHGHQVGDWLLTEVSKRIQYCL
RATDTVGRLGGDEFVVVLPEIYENAKEVANKILNSLEEPFVITNNGVLHISSSIGVAIYPLDAKSQTMLMECADKAMYEA
KKRGRNKVVFFDVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=204, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787541, Length=187, Percent_Identity=36.8983957219251, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=41.6149068322981, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=36.1111111111111, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=34.2541436464088, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=33.8983050847458, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787262, Length=177, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=31.4917127071823, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=30.5389221556886, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081977, Length=150, Percent_Identity=32, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788956, Length=185, Percent_Identity=31.8918918918919, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788085, Length=178, Percent_Identity=29.7752808988764, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=121, Percent_Identity=33.8842975206612, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 75082; Mature: 75082

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS50839 CHASE ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSVKTEFFKFIHSTLPSWLIFSLSLCITFIAWSITTKSNQLHIQELFKFEVAQTIRSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHH
EQRMQEYEQVLRGGVGLFKSSDHVNRLEFHHYISNLHVEKYLTGIQGIGYAVMLKPEEKD
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
TFVNMVRLEGFNDFSVFPEGSRDKYSSILYLEPFTARNQRAFGYDMYSEEARHTAMDIAR
HHEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHC
DNGDIAYSAKVKLVQENGDDLQNGFLIYLPLYRNGAPIENISQRQKELIGYVYSPFRIDN
CCCCEEEEEEEEEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHH
LINGILLGDEIRRINFSIYDGHSENANNLLYAPDRIGAYLPSAYKKESKPAFYVVKTIEF
HHHCEEECCCEEEEEEEEECCCCCCCCCEEECCHHHHHHCCHHHCCCCCCEEEEEEEEEC
PGRNWTIPFYSTSVFEKSVENNLAKLVGISGIFVSVLLLIVMLNITITGKKSMQAKAELE
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHH
ILIDRLKAAASAGIVGIWDWDVEKNILTWDSVMYKLYGLQKSDFEDLYEAWISRVHIDDR
HHHHHHHHHHHCCEEEEEECCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCC
MHIDGEIQAALRHEREYCPEFRVLWPDSSVHYIKAVSKTTFDEIGKPIRMVGVNYDITEQ
EEECHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
KKIQMRLDKEASYDHLTHLPNRRLLNDRLKQAIAFSKRTQKNLAILFIDLDGFKSINDSH
HHEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
GHQVGDWLLTEVSKRIQYCLRATDTVGRLGGDEFVVVLPEIYENAKEVANKILNSLEEPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCE
VITNNGVLHISSSIGVAIYPLDAKSQTMLMECADKAMYEAKKRGRNKVVFFDVA
EEECCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MKRSVKTEFFKFIHSTLPSWLIFSLSLCITFIAWSITTKSNQLHIQELFKFEVAQTIRSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHH
EQRMQEYEQVLRGGVGLFKSSDHVNRLEFHHYISNLHVEKYLTGIQGIGYAVMLKPEEKD
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
TFVNMVRLEGFNDFSVFPEGSRDKYSSILYLEPFTARNQRAFGYDMYSEEARHTAMDIAR
HHEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHC
DNGDIAYSAKVKLVQENGDDLQNGFLIYLPLYRNGAPIENISQRQKELIGYVYSPFRIDN
CCCCEEEEEEEEEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHH
LINGILLGDEIRRINFSIYDGHSENANNLLYAPDRIGAYLPSAYKKESKPAFYVVKTIEF
HHHCEEECCCEEEEEEEEECCCCCCCCCEEECCHHHHHHCCHHHCCCCCCEEEEEEEEEC
PGRNWTIPFYSTSVFEKSVENNLAKLVGISGIFVSVLLLIVMLNITITGKKSMQAKAELE
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHH
ILIDRLKAAASAGIVGIWDWDVEKNILTWDSVMYKLYGLQKSDFEDLYEAWISRVHIDDR
HHHHHHHHHHHCCEEEEEECCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCC
MHIDGEIQAALRHEREYCPEFRVLWPDSSVHYIKAVSKTTFDEIGKPIRMVGVNYDITEQ
EEECHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
KKIQMRLDKEASYDHLTHLPNRRLLNDRLKQAIAFSKRTQKNLAILFIDLDGFKSINDSH
HHEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
GHQVGDWLLTEVSKRIQYCLRATDTVGRLGGDEFVVVLPEIYENAKEVANKILNSLEEPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCE
VITNNGVLHISSSIGVAIYPLDAKSQTMLMECADKAMYEAKKRGRNKVVFFDVA
EEECCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]