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The map label for this gene is ftsW [H]

Identifier: 119944902

GI number: 119944902

Start: 1435005

End: 1436225

Strand: Direct

Name: ftsW [H]

Synonym: Ping_1146

Alternate gene names: 119944902

Gene position: 1435005-1436225 (Clockwise)

Preceding gene: 119944901

Following gene: 119944903

Centisome position: 31.47

GC content: 38.25

Gene sequence:

>1221_bases
ATGGCATTATTTAATCTTTTTATACAAAGGAGTACCAACAATTCCTCTGAGCCCTATGACAGGCAACTTTTAATTGCTAC
GTTTATTCTTATGTGTATTGGCATGGTGATTGTTGCATCTTCTTCAATTCCCGAAGGTATTGCCCTCTCAGCAGATCCCT
TTAGTTTTCTTAAGCGTCAAGCATTCTATTTATTACTTTGTTTAATACTGCTGTGCGCAGTTGTAAGTATTCCTATGGCA
CACTGGTATAAGCATCAAGGAATAATACTTAGTTTGATATTTTTAGGATTGATTGCGGTTCTGCTGGTGGGTACCGAAGT
AAACGGTGCGCATCGCTGGTTGCGATTAGGTCCTGCTAATATACAACCATCAGAATTTGCTAAGCCTGCGATTATTTTCT
TTTTAGCAAGTTATCTGTATCGCCGTCAAAAAGAAGTGATCGATACCATAAAAGGTTTTATGAAACCCCTGATAGTATTA
TTTGCTTTTTCATTATTGTTACTAAAACAGCCCGATTTGGGGTCAATAGTGGTCATTATTGTTATTATGATGGGGATGTT
ATTTATTGCCAATGCAAAGTTGATTTCATTTATTGGTATCGGAGCCGCGTTGTTGACTGCGATCATTGCGCTGATTATGA
CCTCATCTTATCGTATGGAACGTGTTTTTGGATTTTTAGATCCTTGGGCTGAGCCCTTTGGCCGAAGTTATCAATTAACT
CAATCGCTGATGGCCTTTGGCCGGGGTGGTTGGTTTGGACAAGGTTTAGGCAATTCCGTCCAAAAATTAGAATATCTACC
CGAAGCACATACGGATTTTATAATGGCAATACTGGCAGAAGAATTAGGTTTTATAGGTGTTAGTCTGGTCCTTATTTTGG
AATTTTATTTGGTTTATAAAGCCTTTTCTATTGGTAAAAATGCCCTTAAGCAAACCTTTGTTTTCGCTGGTTATGTTGCT
ATCGGTATTGCCATTTGGTTTTTTTTCCAAACGGCTGTTAATATTGGCGCTGCATCTGGCATTGCGCCAACCAAAGGGTT
AACGCTTCCTTTAGTGAGTTATGGCGGCTCTAGCCTGATTACTATCTCGCTGGCAATAGGTTTATTATTACGTATTGATT
ATGAAACCCGTATTGCAACTGCAGAAACGCTTATTAAAAAAATCAAAGGATCTAAAAAAGCTAAATTAAAAGAAACAGTA
GGTGAAGTTGATGCGCAATAA

Upstream 100 bases:

>100_bases
TAAGCCCTGCTTGTGCCAGTTTAGATATGTATAAAAACTTTATGCAACGAGGAGATCACTTTAAACGCTTAGTCAAGGCA
TTGCCAGCGAGAAAAAACTG

Downstream 100 bases:

>100_bases
AAAAACATTAGTGGTCATGGCAGGCGGTACCGGTGGGCATGTATTCCCGGGACTTGCAGTGGCAGATGCACTAAAAGAGC
AGGGTTGGGCAGTCAGTTGG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MALFNLFIQRSTNNSSEPYDRQLLIATFILMCIGMVIVASSSIPEGIALSADPFSFLKRQAFYLLLCLILLCAVVSIPMA
HWYKHQGIILSLIFLGLIAVLLVGTEVNGAHRWLRLGPANIQPSEFAKPAIIFFLASYLYRRQKEVIDTIKGFMKPLIVL
FAFSLLLLKQPDLGSIVVIIVIMMGMLFIANAKLISFIGIGAALLTAIIALIMTSSYRMERVFGFLDPWAEPFGRSYQLT
QSLMAFGRGGWFGQGLGNSVQKLEYLPEAHTDFIMAILAEELGFIGVSLVLILEFYLVYKAFSIGKNALKQTFVFAGYVA
IGIAIWFFFQTAVNIGAASGIAPTKGLTLPLVSYGGSSLITISLAIGLLLRIDYETRIATAETLIKKIKGSKKAKLKETV
GEVDAQ

Sequences:

>Translated_406_residues
MALFNLFIQRSTNNSSEPYDRQLLIATFILMCIGMVIVASSSIPEGIALSADPFSFLKRQAFYLLLCLILLCAVVSIPMA
HWYKHQGIILSLIFLGLIAVLLVGTEVNGAHRWLRLGPANIQPSEFAKPAIIFFLASYLYRRQKEVIDTIKGFMKPLIVL
FAFSLLLLKQPDLGSIVVIIVIMMGMLFIANAKLISFIGIGAALLTAIIALIMTSSYRMERVFGFLDPWAEPFGRSYQLT
QSLMAFGRGGWFGQGLGNSVQKLEYLPEAHTDFIMAILAEELGFIGVSLVLILEFYLVYKAFSIGKNALKQTFVFAGYVA
IGIAIWFFFQTAVNIGAASGIAPTKGLTLPLVSYGGSSLITISLAIGLLLRIDYETRIATAETLIKKIKGSKKAKLKETV
GEVDAQ
>Mature_405_residues
ALFNLFIQRSTNNSSEPYDRQLLIATFILMCIGMVIVASSSIPEGIALSADPFSFLKRQAFYLLLCLILLCAVVSIPMAH
WYKHQGIILSLIFLGLIAVLLVGTEVNGAHRWLRLGPANIQPSEFAKPAIIFFLASYLYRRQKEVIDTIKGFMKPLIVLF
AFSLLLLKQPDLGSIVVIIVIMMGMLFIANAKLISFIGIGAALLTAIIALIMTSSYRMERVFGFLDPWAEPFGRSYQLTQ
SLMAFGRGGWFGQGLGNSVQKLEYLPEAHTDFIMAILAEELGFIGVSLVLILEFYLVYKAFSIGKNALKQTFVFAGYVAI
GIAIWFFFQTAVNIGAASGIAPTKGLTLPLVSYGGSSLITISLAIGLLLRIDYETRIATAETLIKKIKGSKKAKLKETVG
EVDAQ

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=378, Percent_Identity=50.2645502645503, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1786853, Length=336, Percent_Identity=33.9285714285714, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44577; Mature: 44446

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFNLFIQRSTNNSSEPYDRQLLIATFILMCIGMVIVASSSIPEGIALSADPFSFLKRQ
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
AFYLLLCLILLCAVVSIPMAHWYKHQGIILSLIFLGLIAVLLVGTEVNGAHRWLRLGPAN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCC
IQPSEFAKPAIIFFLASYLYRRQKEVIDTIKGFMKPLIVLFAFSLLLLKQPDLGSIVVII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VIMMGMLFIANAKLISFIGIGAALLTAIIALIMTSSYRMERVFGFLDPWAEPFGRSYQLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHH
QSLMAFGRGGWFGQGLGNSVQKLEYLPEAHTDFIMAILAEELGFIGVSLVLILEFYLVYK
HHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFSIGKNALKQTFVFAGYVAIGIAIWFFFQTAVNIGAASGIAPTKGLTLPLVSYGGSSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHCCCCHHH
TISLAIGLLLRIDYETRIATAETLIKKIKGSKKAKLKETVGEVDAQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALFNLFIQRSTNNSSEPYDRQLLIATFILMCIGMVIVASSSIPEGIALSADPFSFLKRQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
AFYLLLCLILLCAVVSIPMAHWYKHQGIILSLIFLGLIAVLLVGTEVNGAHRWLRLGPAN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCC
IQPSEFAKPAIIFFLASYLYRRQKEVIDTIKGFMKPLIVLFAFSLLLLKQPDLGSIVVII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VIMMGMLFIANAKLISFIGIGAALLTAIIALIMTSSYRMERVFGFLDPWAEPFGRSYQLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHH
QSLMAFGRGGWFGQGLGNSVQKLEYLPEAHTDFIMAILAEELGFIGVSLVLILEFYLVYK
HHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFSIGKNALKQTFVFAGYVAIGIAIWFFFQTAVNIGAASGIAPTKGLTLPLVSYGGSSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHCCCCHHH
TISLAIGLLLRIDYETRIATAETLIKKIKGSKKAKLKETVGEVDAQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]