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The map label for this gene is mraY

Identifier: 119944900

GI number: 119944900

Start: 1432584

End: 1433666

Strand: Direct

Name: mraY

Synonym: Ping_1144

Alternate gene names: 119944900

Gene position: 1432584-1433666 (Clockwise)

Preceding gene: 119944899

Following gene: 119944901

Centisome position: 31.42

GC content: 40.17

Gene sequence:

>1083_bases
ATGATCGTCTGGTTAGCAGAGTTACTTTCAAGCCAATTTACATTTTTAAATGTACTAACATATCTGTCAGTGCGAACAGT
TATGGCGGTATTAACCGCGTTAGCATTTTCGCTGTTTTTTGGGCCTAAATTAATACGTTTTTTACAAAAGTTTCAGATTG
GTCAAATCGTCCGGCAGGATGGCCCAGAATCTCATTTCAGTAAGGCTGGGACGCCAACCATGGGTGGTATTTTGATTCTT
GGTGCAATCACCTTCTCAAGCTTATTATGGGCTAGATTGGACAATTCTTATGTTTGGATAGTGCTGTTCACAACGCTTGC
TTTTGGTGCAATTGGTTTTATGGATGACTATTTAAAAGTGGTCCGTAAACACCCTGACGGTTTAATTGCCCGCTGGAAAT
ATTTTTGGCAATCTGTTACTGCGCTTGTTCTTGCTGTTGTCTTATTTTTAAGCGCAACAACGCCGGCGGAACTGACTTTT
GTTATGCCATTTTTTAAACAATATATGCCTTATCTTGGTTTGGCTTTTATTCCCTTAGTCTATTTTACCGTGGTAGGTAG
CAGTAATGCTGTTAATTTGACCGATGGTTTAGATGGATTGGCTATTATGCCGACTGTGATGGTTGCAGCTGCATTTGCAT
TAATTGCCTACCTGACAAGCCATGTTAATTATGCGCATTATTTGTATATTCCCTACATTCCTAAGGCCAGTGAATTGGTG
GTTATCTGCGGTACTATAGTAGGAGCGGGGTTAGGGTTTTTATGGTTCAATACCTATCCTGCACAAGTGTTTATGGGTGA
TGTGGGTTCACTGGCATTAGGGGCTTTACTCGGTGTAATTGCTGTTTTGGTTCGTCAAGAAATCCTGCTGGTTATTATGG
GGGGGATATTTGTAGTGGAAACACTGTCGGTTATTTTACAGGTAGGTTCATATAAAATGCGTAAACGGCGTATTTTTAGA
ATGGCACCCATTCATCATCATTATGAGAAAAAAGGTTGGCCTGAGCCGCGTGTTATTGTCCGTTTTTGGATTATTACCAT
AGTGTTAGTATTAATAGGTTTAGTGACCTTAAAGGTACGTTAA

Upstream 100 bases:

>100_bases
TTCAAAAATGGAAGAGGTTGTTAACTTTATCAAGCAGGCAGCCAATAAATTCAGCGCTTGATGTGCTAACAATAATAATT
AAATAATAGGGTATAAGACT

Downstream 100 bases:

>100_bases
AATGTCAAACCAACAGATTGCAGTACTAGGGCTTGGAGAAACCGGATTATCTTGTGTTAATTTTTTATTAAAACAAGGTG
AGCAAGTGACTGTATTTGAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIVWLAELLSSQFTFLNVLTYLSVRTVMAVLTALAFSLFFGPKLIRFLQKFQIGQIVRQDGPESHFSKAGTPTMGGILIL
GAITFSSLLWARLDNSYVWIVLFTTLAFGAIGFMDDYLKVVRKHPDGLIARWKYFWQSVTALVLAVVLFLSATTPAELTF
VMPFFKQYMPYLGLAFIPLVYFTVVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLTSHVNYAHYLYIPYIPKASELV
VICGTIVGAGLGFLWFNTYPAQVFMGDVGSLALGALLGVIAVLVRQEILLVIMGGIFVVETLSVILQVGSYKMRKRRIFR
MAPIHHHYEKKGWPEPRVIVRFWIITIVLVLIGLVTLKVR

Sequences:

>Translated_360_residues
MIVWLAELLSSQFTFLNVLTYLSVRTVMAVLTALAFSLFFGPKLIRFLQKFQIGQIVRQDGPESHFSKAGTPTMGGILIL
GAITFSSLLWARLDNSYVWIVLFTTLAFGAIGFMDDYLKVVRKHPDGLIARWKYFWQSVTALVLAVVLFLSATTPAELTF
VMPFFKQYMPYLGLAFIPLVYFTVVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLTSHVNYAHYLYIPYIPKASELV
VICGTIVGAGLGFLWFNTYPAQVFMGDVGSLALGALLGVIAVLVRQEILLVIMGGIFVVETLSVILQVGSYKMRKRRIFR
MAPIHHHYEKKGWPEPRVIVRFWIITIVLVLIGLVTLKVR
>Mature_360_residues
MIVWLAELLSSQFTFLNVLTYLSVRTVMAVLTALAFSLFFGPKLIRFLQKFQIGQIVRQDGPESHFSKAGTPTMGGILIL
GAITFSSLLWARLDNSYVWIVLFTTLAFGAIGFMDDYLKVVRKHPDGLIARWKYFWQSVTALVLAVVLFLSATTPAELTF
VMPFFKQYMPYLGLAFIPLVYFTVVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLTSHVNYAHYLYIPYIPKASELV
VICGTIVGAGLGFLWFNTYPAQVFMGDVGSLALGALLGVIAVLVRQEILLVIMGGIFVVETLSVILQVGSYKMRKRRIFR
MAPIHHHYEKKGWPEPRVIVRFWIITIVLVLIGLVTLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=67.2222222222222, Blast_Score=481, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PSYIN (A1SU16)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942580.1
- STRING:   A1SU16
- GeneID:   4623885
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1144
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   HATLSAY
- PhylomeDB:   A1SU16
- BioCyc:   PING357804:PING_1144-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40118; Mature: 40118

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16d2710c)-; HASH(0x175d0820)-; HASH(0x1760a9c8)-; HASH(0x1760a9d4)-; HASH(0x175d0934)-; HASH(0x1733d178)-; HASH(0x165d30cc)-; HASH(0x1761cef8)-; HASH(0x1760a74c)-; HASH(0x15fba8cc)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVWLAELLSSQFTFLNVLTYLSVRTVMAVLTALAFSLFFGPKLIRFLQKFQIGQIVRQD
CEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHFSKAGTPTMGGILILGAITFSSLLWARLDNSYVWIVLFTTLAFGAIGFMDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHH
VRKHPDGLIARWKYFWQSVTALVLAVVLFLSATTPAELTFVMPFFKQYMPYLGLAFIPLV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YFTVVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLTSHVNYAHYLYIPYIPKASELV
HHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHH
VICGTIVGAGLGFLWFNTYPAQVFMGDVGSLALGALLGVIAVLVRQEILLVIMGGIFVVE
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKMRKRRIFRMAPIHHHYEKKGWPEPRVIVRFWIITIVLVLIGLVTLKVR
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MIVWLAELLSSQFTFLNVLTYLSVRTVMAVLTALAFSLFFGPKLIRFLQKFQIGQIVRQD
CEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHFSKAGTPTMGGILILGAITFSSLLWARLDNSYVWIVLFTTLAFGAIGFMDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHH
VRKHPDGLIARWKYFWQSVTALVLAVVLFLSATTPAELTFVMPFFKQYMPYLGLAFIPLV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YFTVVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLTSHVNYAHYLYIPYIPKASELV
HHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHH
VICGTIVGAGLGFLWFNTYPAQVFMGDVGSLALGALLGVIAVLVRQEILLVIMGGIFVVE
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKMRKRRIFRMAPIHHHYEKKGWPEPRVIVRFWIITIVLVLIGLVTLKVR
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA