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The map label for this gene is rsmH

Identifier: 119944895

GI number: 119944895

Start: 1426374

End: 1427321

Strand: Direct

Name: rsmH

Synonym: Ping_1139

Alternate gene names: 119944895

Gene position: 1426374-1427321 (Clockwise)

Preceding gene: 119944894

Following gene: 119944896

Centisome position: 31.28

GC content: 44.09

Gene sequence:

>948_bases
ATGGCAAAACATACAACAGTATTATTGGATGAAGCGGTTAACGGCTTAGGTTTAAAAACAGACGGTATATATGTAGATGG
TACCTTTGGACGTGGAGGGCATTCTCGGCATATTCTTGGCCAGTTAGGGGCACAGGGAAGATTAATAGCAATCGATCGTG
ATCCACGTGCGATTGAGACCGGCGAAGCGCTGATGAAAGAAGATCCTCGTTTTACTATTATCCATGGTCCATTCTCCGGG
TTAGCGGAATATATAAAAGAGTTGGGGCTCGCAGGGCAAATAGATGGTGTGTTATTAGATCTGGGTGTTTCTTCTCCGCA
AATTGATGATGCTGATCGTGGTTTTAGTTTTATGCGTGATGGCCCGTTGGATATGCGCATGGATCCTACCTCGGGTATAA
GTGCAGCACAGTGGTTGGCAAAAGCGGATGTTGATGACATTGGATGGGTATTAAAAACCTTTGGAGAGGAAAAGTTTGCC
TTCCGTATTGCCCGCGCTATCGTTGCGGATCGCACGGAAACACCCTTTTTACGCACGCTGCAATTGGCTCAATTAATTGA
ACGTCTCTGTCCTAAAAGAGAAAAGAAAAAACATCCTGCAACCCGCAGTTTCCAGGCTATCCGGATTTATGTTAATAGTG
AATTGGAAGAGATTCATAAAGTACTTGATGGCGCACTGGAGATATTAGCTATTGGTGGACAGTTATCGGTGATCAGTTTC
CATTCTTTAGAAGACAGAATAGTTAAACGTTTTATACGTAAACAGGAGAAAGGGCGAGAGTACCCCCCCGGTTTACCCTT
AACAGAAGCACAGATGCAACATGGCAAAACGCTTAAATCTCTCGCTAAAGCACTAAAACCAAGTGCGGAAGAAATTAATG
AGAATACGCGAGCACGCAGCTCTGTTTTACGTGTTGCACAGAAAATAGCAGAACCAGAGAGCGAATAA

Upstream 100 bases:

>100_bases
GGGACGAAGATATGTGGAATCAACAGATAAAAAATGATTTAGAGGATGGGTTGCCGACAGGAATAGAATTAAGTTCAGGG
TTAAGGGAGTTTTCACTTTA

Downstream 100 bases:

>100_bases
CTTGAGCACACCCAATACGCATTTATTATGTTTAATAGCCACCGATTTACGCAAACATTTTTTTGCTGTTTTGGTTGGGA
TGCTGATTGTATGTAGCGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MAKHTTVLLDEAVNGLGLKTDGIYVDGTFGRGGHSRHILGQLGAQGRLIAIDRDPRAIETGEALMKEDPRFTIIHGPFSG
LAEYIKELGLAGQIDGVLLDLGVSSPQIDDADRGFSFMRDGPLDMRMDPTSGISAAQWLAKADVDDIGWVLKTFGEEKFA
FRIARAIVADRTETPFLRTLQLAQLIERLCPKREKKKHPATRSFQAIRIYVNSELEEIHKVLDGALEILAIGGQLSVISF
HSLEDRIVKRFIRKQEKGREYPPGLPLTEAQMQHGKTLKSLAKALKPSAEEINENTRARSSVLRVAQKIAEPESE

Sequences:

>Translated_315_residues
MAKHTTVLLDEAVNGLGLKTDGIYVDGTFGRGGHSRHILGQLGAQGRLIAIDRDPRAIETGEALMKEDPRFTIIHGPFSG
LAEYIKELGLAGQIDGVLLDLGVSSPQIDDADRGFSFMRDGPLDMRMDPTSGISAAQWLAKADVDDIGWVLKTFGEEKFA
FRIARAIVADRTETPFLRTLQLAQLIERLCPKREKKKHPATRSFQAIRIYVNSELEEIHKVLDGALEILAIGGQLSVISF
HSLEDRIVKRFIRKQEKGREYPPGLPLTEAQMQHGKTLKSLAKALKPSAEEINENTRARSSVLRVAQKIAEPESE
>Mature_314_residues
AKHTTVLLDEAVNGLGLKTDGIYVDGTFGRGGHSRHILGQLGAQGRLIAIDRDPRAIETGEALMKEDPRFTIIHGPFSGL
AEYIKELGLAGQIDGVLLDLGVSSPQIDDADRGFSFMRDGPLDMRMDPTSGISAAQWLAKADVDDIGWVLKTFGEEKFAF
RIARAIVADRTETPFLRTLQLAQLIERLCPKREKKKHPATRSFQAIRIYVNSELEEIHKVLDGALEILAIGGQLSVISFH
SLEDRIVKRFIRKQEKGREYPPGLPLTEAQMQHGKTLKSLAKALKPSAEEINENTRARSSVLRVAQKIAEPESE

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=348, Percent_Identity=38.2183908045977, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI165377202, Length=196, Percent_Identity=42.3469387755102, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1786270, Length=308, Percent_Identity=64.6103896103896, Blast_Score=407, Evalue=1e-115,
Organism=Drosophila melanogaster, GI62472493, Length=331, Percent_Identity=39.8791540785499, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28571637, Length=331, Percent_Identity=39.8791540785499, Blast_Score=193, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_PSYIN (A1SU11)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942575.1
- ProteinModelPortal:   A1SU11
- SMR:   A1SU11
- STRING:   A1SU11
- GeneID:   4623880
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1139
- eggNOG:   COG0275
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- PhylomeDB:   A1SU11
- BioCyc:   PING357804:PING_1139-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 34840; Mature: 34709

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: BINDING 52-52 BINDING 78-78 BINDING 100-100 BINDING 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHTTVLLDEAVNGLGLKTDGIYVDGTFGRGGHSRHILGQLGAQGRLIAIDRDPRAIET
CCCCHHHHHHHHHCCCCCEECCEEEECCCCCCCCCHHHHHHCCCCCEEEEECCCCCCHHH
GEALMKEDPRFTIIHGPFSGLAEYIKELGLAGQIDGVLLDLGVSSPQIDDADRGFSFMRD
HHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCC
GPLDMRMDPTSGISAAQWLAKADVDDIGWVLKTFGEEKFAFRIARAIVADRTETPFLRTL
CCCCEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
QLAQLIERLCPKREKKKHPATRSFQAIRIYVNSELEEIHKVLDGALEILAIGGQLSVISF
HHHHHHHHHCCHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEEEH
HSLEDRIVKRFIRKQEKGREYPPGLPLTEAQMQHGKTLKSLAKALKPSAEEINENTRARS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHH
SVLRVAQKIAEPESE
HHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKHTTVLLDEAVNGLGLKTDGIYVDGTFGRGGHSRHILGQLGAQGRLIAIDRDPRAIET
CCCHHHHHHHHHCCCCCEECCEEEECCCCCCCCCHHHHHHCCCCCEEEEECCCCCCHHH
GEALMKEDPRFTIIHGPFSGLAEYIKELGLAGQIDGVLLDLGVSSPQIDDADRGFSFMRD
HHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCC
GPLDMRMDPTSGISAAQWLAKADVDDIGWVLKTFGEEKFAFRIARAIVADRTETPFLRTL
CCCCEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
QLAQLIERLCPKREKKKHPATRSFQAIRIYVNSELEEIHKVLDGALEILAIGGQLSVISF
HHHHHHHHHCCHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEEEH
HSLEDRIVKRFIRKQEKGREYPPGLPLTEAQMQHGKTLKSLAKALKPSAEEINENTRARS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHH
SVLRVAQKIAEPESE
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA