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The map label for this gene is hda [H]

Identifier: 119944829

GI number: 119944829

Start: 1345395

End: 1346123

Strand: Direct

Name: hda [H]

Synonym: Ping_1071

Alternate gene names: 119944829

Gene position: 1345395-1346123 (Clockwise)

Preceding gene: 119944828

Following gene: 119944835

Centisome position: 29.51

GC content: 38.41

Gene sequence:

>729_bases
ATGCCGCAGGATGAATTACGTTTTCAATATCCTTTATTAGCACTTAAATTTCCTGATGATGAAACCTTTGCAAGTTTTTA
TCCTGGTCAAAATTACAGTGTATTAACACAATTAAAAAATAGTGTTGTGGGTCTGGGTGAGCCGGTCTTATATATGTGGG
GAGAATCTGGTAGCGGTCGTTCTCATTTATTACATGCTTTATGTTCAGAAGTCGATGAGCGTGGCGACAGTGTTGCCTAT
ATTCCACTGCGACATTACCAGAGTATGACGTTAGATATTTTTGAAAATATGGAACAGGTAACGCTTGTCTGCATCGATGA
TATTGAGGAAATCGCCGGTGATGAAAAATGGGAAAAAGCACTTTTTGATTTTTATAATCGCTGGTCCGATAATAAAGAAA
ATCGTTCATCGGGTGCCAGTTTAGTGTTTTGCGCAAATCATTTACCTAAGCAACTTGGTCTAAAACTTAATGATCTTGTT
TCACGACTTGAATGGGGGGCTTGTTACCATTTAACCCCGCTTAATGAAGAAGACAAGCTAGGTGCTCTGCAATTACGTGC
TCAATTAAAGGGCATGAAGTTGCCTGTAGATGTTGGGCGTTTTTTATTAAATCGTCTATCACGGGATATGAATACGTTAT
TGGACACGCTTGATCAATTAGATAATGCATCGCTAGAAGCTAAGCGTAAATTAACGATTCCCTTTGTCAAAGAGGTATTA
GTCTTATAA

Upstream 100 bases:

>100_bases
TAATAGTTTTGAAAATGCACTTAATATACAAACTAACTTACAATTAGATGCTTCTCAAAGTGAACGTTTTCACTTTAACT
GGCGTTAATTAGGGAACTTC

Downstream 100 bases:

>100_bases
AGCTTGGGGATAAAGCACTTCAAGATGCAGCATCTTGAAGTGAGGGAAGTTGACTCTTTTCTAGTGACTCTTTTTCTTAC
GAATGCTTAAGCCTAATTCA

Product: chromosomal replication initiator, DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MPQDELRFQYPLLALKFPDDETFASFYPGQNYSVLTQLKNSVVGLGEPVLYMWGESGSGRSHLLHALCSEVDERGDSVAY
IPLRHYQSMTLDIFENMEQVTLVCIDDIEEIAGDEKWEKALFDFYNRWSDNKENRSSGASLVFCANHLPKQLGLKLNDLV
SRLEWGACYHLTPLNEEDKLGALQLRAQLKGMKLPVDVGRFLLNRLSRDMNTLLDTLDQLDNASLEAKRKLTIPFVKEVL
VL

Sequences:

>Translated_242_residues
MPQDELRFQYPLLALKFPDDETFASFYPGQNYSVLTQLKNSVVGLGEPVLYMWGESGSGRSHLLHALCSEVDERGDSVAY
IPLRHYQSMTLDIFENMEQVTLVCIDDIEEIAGDEKWEKALFDFYNRWSDNKENRSSGASLVFCANHLPKQLGLKLNDLV
SRLEWGACYHLTPLNEEDKLGALQLRAQLKGMKLPVDVGRFLLNRLSRDMNTLLDTLDQLDNASLEAKRKLTIPFVKEVL
VL
>Mature_241_residues
PQDELRFQYPLLALKFPDDETFASFYPGQNYSVLTQLKNSVVGLGEPVLYMWGESGSGRSHLLHALCSEVDERGDSVAYI
PLRHYQSMTLDIFENMEQVTLVCIDDIEEIAGDEKWEKALFDFYNRWSDNKENRSSGASLVFCANHLPKQLGLKLNDLVS
RLEWGACYHLTPLNEEDKLGALQLRAQLKGMKLPVDVGRFLLNRLSRDMNTLLDTLDQLDNASLEAKRKLTIPFVKEVLV
L

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=230, Percent_Identity=54.7826086956522, Blast_Score=251, Evalue=2e-68,
Organism=Escherichia coli, GI2367267, Length=235, Percent_Identity=22.9787234042553, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 27601; Mature: 27470

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQDELRFQYPLLALKFPDDETFASFYPGQNYSVLTQLKNSVVGLGEPVLYMWGESGSGR
CCCCHHEEECCEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCH
SHLLHALCSEVDERGDSVAYIPLRHYQSMTLDIFENMEQVTLVCIDDIEEIAGDEKWEKA
HHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCHHHEEEHHHHHHHHHHCCHHHHHH
LFDFYNRWSDNKENRSSGASLVFCANHLPKQLGLKLNDLVSRLEWGACYHLTPLNEEDKL
HHHHHHHHCCCCCCCCCCCEEEEECHHCHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCH
GALQLRAQLKGMKLPVDVGRFLLNRLSRDMNTLLDTLDQLDNASLEAKRKLTIPFVKEVL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHH
VL
CC
>Mature Secondary Structure 
PQDELRFQYPLLALKFPDDETFASFYPGQNYSVLTQLKNSVVGLGEPVLYMWGESGSGR
CCCHHEEECCEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCH
SHLLHALCSEVDERGDSVAYIPLRHYQSMTLDIFENMEQVTLVCIDDIEEIAGDEKWEKA
HHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCHHHEEEHHHHHHHHHHCCHHHHHH
LFDFYNRWSDNKENRSSGASLVFCANHLPKQLGLKLNDLVSRLEWGACYHLTPLNEEDKL
HHHHHHHHCCCCCCCCCCCEEEEECHHCHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCH
GALQLRAQLKGMKLPVDVGRFLLNRLSRDMNTLLDTLDQLDNASLEAKRKLTIPFVKEVL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHH
VL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA