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The map label for this gene is uspA [H]

Identifier: 119944719

GI number: 119944719

Start: 1204814

End: 1205260

Strand: Direct

Name: uspA [H]

Synonym: Ping_0959

Alternate gene names: 119944719

Gene position: 1204814-1205260 (Clockwise)

Preceding gene: 119944718

Following gene: 119944725

Centisome position: 26.42

GC content: 39.15

Gene sequence:

>447_bases
ATGATGAACTATGAGCATATTTTAGTTACTGTTAATTTAACTAAAATCAACCAACAAGTCATTGATCGAGCGTTATCATT
AGCAAAAGCGACGGGCGCTAAAGTTTCATTCATTCATGTGGATCTCAGTTGTACAGAGAACTTTTCTATTTTAAGGGAGT
GTGATGAAACGCCTGCTGAAGAGATATCTAATTCGAAGAGTGCATCGAAAGAGGAATTACAACGGCAGTTGCAGGCATTA
GCTGATCGGGCTGATTACCCTATTACAAATACATTGGTCGTAAGCGGTGGATTGCGTTATAAATTGGAACAAACTATTCG
AAAAATGGATGTTGACCTGCTCGTTTGTGGACACCATCATAATTTTTGGAGCCGTGTTGTCTCTTCAGTGCGTGAGCTAG
TGGACACTTCTCCTATAGATTTACTTATTGTTCATCTAGATGACTGA

Upstream 100 bases:

>100_bases
CTAAGAACTCAAGGTTTTTTTGGGGCATTTTAAAAGAGTATTGTAATGAATTAATTGGCATTGGTGCTAATCTTAAGAGA
GAAAGCTGAAGGTGGAGAAA

Downstream 100 bases:

>100_bases
TCATTAATTTCGCTCACTCGTTATATTATCTGTGGCTTTATTTTTTTAACTGATAATGATCAGATTAAAAGCTGTTTTAT
CGCTTTGCACAGAGTGTATA

Product: universal stress protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MMNYEHILVTVNLTKINQQVIDRALSLAKATGAKVSFIHVDLSCTENFSILRECDETPAEEISNSKSASKEELQRQLQAL
ADRADYPITNTLVVSGGLRYKLEQTIRKMDVDLLVCGHHHNFWSRVVSSVRELVDTSPIDLLIVHLDD

Sequences:

>Translated_148_residues
MMNYEHILVTVNLTKINQQVIDRALSLAKATGAKVSFIHVDLSCTENFSILRECDETPAEEISNSKSASKEELQRQLQAL
ADRADYPITNTLVVSGGLRYKLEQTIRKMDVDLLVCGHHHNFWSRVVSSVRELVDTSPIDLLIVHLDD
>Mature_148_residues
MMNYEHILVTVNLTKINQQVIDRALSLAKATGAKVSFIHVDLSCTENFSILRECDETPAEEISNSKSASKEELQRQLQAL
ADRADYPITNTLVVSGGLRYKLEQTIRKMDVDLLVCGHHHNFWSRVVSSVRELVDTSPIDLLIVHLDD

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=147, Percent_Identity=39.4557823129252, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1788205, Length=146, Percent_Identity=30.8219178082192, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790358, Length=147, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=4e-13,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 16690; Mature: 16690

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNYEHILVTVNLTKINQQVIDRALSLAKATGAKVSFIHVDLSCTENFSILRECDETPAE
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHCCCCHH
EISNSKSASKEELQRQLQALADRADYPITNTLVVSGGLRYKLEQTIRKMDVDLLVCGHHH
HHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCC
NFWSRVVSSVRELVDTSPIDLLIVHLDD
HHHHHHHHHHHHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MMNYEHILVTVNLTKINQQVIDRALSLAKATGAKVSFIHVDLSCTENFSILRECDETPAE
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHCCCCHH
EISNSKSASKEELQRQLQALADRADYPITNTLVVSGGLRYKLEQTIRKMDVDLLVCGHHH
HHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCC
NFWSRVVSSVRELVDTSPIDLLIVHLDD
HHHHHHHHHHHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]