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The map label for this gene is fnr [H]

Identifier: 119944692

GI number: 119944692

Start: 1166268

End: 1167017

Strand: Reverse

Name: fnr [H]

Synonym: Ping_0931

Alternate gene names: 119944692

Gene position: 1167017-1166268 (Counterclockwise)

Preceding gene: 119944693

Following gene: 119944691

Centisome position: 25.59

GC content: 38.13

Gene sequence:

>750_bases
ATGACTATGGAAAAAAGTAATACTAATCGAATTCAAAGCAGTCGTTCTGCTATTCATTGTCAAGACTGCAGTATAAGCCA
ATTGTGCATTCCTTATTCGCTCAATGAAGATGAATTAGAGCGTTTAGATAATATTATAGAGCGGAAAAAACCGATTCAAA
AAGGACAAGAAATATTTAAAGCGGGTCAAGAGATGAAATGCCTTTATGCCATTCGCTCTGGTACGTTAAAGTCCTATACG
ATTACAGAACAAGGTGATGAGCAAATTACTGCTTTTCATCTCGCTGGTGATTTAATTGGTTTTGATGCGATTAGCTCGGG
GACTCATCCAAGTTTCTCCCAAGCACTTGAAACTTCGATGATTTGTGAAATTCCCTATGACACACTGGATACACTTTCTA
TTAGCATGCCAAAGCTGAGGCAGCAAATATTACGCTTAATGAGCGGTGAAATTGTTGGCGATCAAAATATGATTTTATTA
CTTTCTAAGAAAAATGCTGAAGAACGACTTGCGTCGTTTATTTTCGACTTATCACAGCGTTTTGCGGCACGAGGATTTTC
ACCGAAAGAGTTTCGTTTATCTATGACGCGTGGCGATATCGGTAATTATTTAGGTCTCACGGTTGAAACTATCAGCCGTC
TTTTAGGACGTTTTCAAAAAATGGAGATGATTGCTGTTAAAGGTAAATATATTAGCATCTTAGATGATGCGCAACTGACT
CTTCTGGCTGGCGCATTGAAAAAAGATTAG

Upstream 100 bases:

>100_bases
ATTTGATACTTTCACTGTGATAAATATTTAATTATTAGCATCTATTCAAAGCAAGTTGAATAGATGCTAATATCGATGCG
TATCAATTATGGGAAAAATA

Downstream 100 bases:

>100_bases
GTTAACTCACAGATCTATAACTATCTGGTATAAGTAGCCTTTTGATCTAAAAAAAGCTAACAATTTTACTTTTTTTGATA
TAAGTTATAGGTATCTTTCA

Product: fumarate/nitrate reduction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTMEKSNTNRIQSSRSAIHCQDCSISQLCIPYSLNEDELERLDNIIERKKPIQKGQEIFKAGQEMKCLYAIRSGTLKSYT
ITEQGDEQITAFHLAGDLIGFDAISSGTHPSFSQALETSMICEIPYDTLDTLSISMPKLRQQILRLMSGEIVGDQNMILL
LSKKNAEERLASFIFDLSQRFAARGFSPKEFRLSMTRGDIGNYLGLTVETISRLLGRFQKMEMIAVKGKYISILDDAQLT
LLAGALKKD

Sequences:

>Translated_249_residues
MTMEKSNTNRIQSSRSAIHCQDCSISQLCIPYSLNEDELERLDNIIERKKPIQKGQEIFKAGQEMKCLYAIRSGTLKSYT
ITEQGDEQITAFHLAGDLIGFDAISSGTHPSFSQALETSMICEIPYDTLDTLSISMPKLRQQILRLMSGEIVGDQNMILL
LSKKNAEERLASFIFDLSQRFAARGFSPKEFRLSMTRGDIGNYLGLTVETISRLLGRFQKMEMIAVKGKYISILDDAQLT
LLAGALKKD
>Mature_248_residues
TMEKSNTNRIQSSRSAIHCQDCSISQLCIPYSLNEDELERLDNIIERKKPIQKGQEIFKAGQEMKCLYAIRSGTLKSYTI
TEQGDEQITAFHLAGDLIGFDAISSGTHPSFSQALETSMICEIPYDTLDTLSISMPKLRQQILRLMSGEIVGDQNMILLL
SKKNAEERLASFIFDLSQRFAARGFSPKEFRLSMTRGDIGNYLGLTVETISRLLGRFQKMEMIAVKGKYISILDDAQLTL
LAGALKKD

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=244, Percent_Identity=77.8688524590164, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27948; Mature: 27816

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMEKSNTNRIQSSRSAIHCQDCSISQLCIPYSLNEDELERLDNIIERKKPIQKGQEIFK
CCCCCCCCHHHHHCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHH
AGQEMKCLYAIRSGTLKSYTITEQGDEQITAFHLAGDLIGFDAISSGTHPSFSQALETSM
CCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHH
ICEIPYDTLDTLSISMPKLRQQILRLMSGEIVGDQNMILLLSKKNAEERLASFIFDLSQR
EEECCCCCHHHHCCCHHHHHHHHHHHHCCCEECCCCEEEEEECCCHHHHHHHHHHHHHHH
FAARGFSPKEFRLSMTRGDIGNYLGLTVETISRLLGRFQKMEMIAVKGKYISILDDAQLT
HHHCCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCHHH
LLAGALKKD
HHHHHHCCC
>Mature Secondary Structure 
TMEKSNTNRIQSSRSAIHCQDCSISQLCIPYSLNEDELERLDNIIERKKPIQKGQEIFK
CCCCCCCHHHHHCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHH
AGQEMKCLYAIRSGTLKSYTITEQGDEQITAFHLAGDLIGFDAISSGTHPSFSQALETSM
CCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHH
ICEIPYDTLDTLSISMPKLRQQILRLMSGEIVGDQNMILLLSKKNAEERLASFIFDLSQR
EEECCCCCHHHHCCCHHHHHHHHHHHHCCCEECCCCEEEEEECCCHHHHHHHHHHHHHHH
FAARGFSPKEFRLSMTRGDIGNYLGLTVETISRLLGRFQKMEMIAVKGKYISILDDAQLT
HHHCCCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCHHH
LLAGALKKD
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA