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The map label for this gene is carA [H]

Identifier: 119944657

GI number: 119944657

Start: 1122191

End: 1123327

Strand: Direct

Name: carA [H]

Synonym: Ping_0896

Alternate gene names: 119944657

Gene position: 1122191-1123327 (Clockwise)

Preceding gene: 119944656

Following gene: 119944658

Centisome position: 24.61

GC content: 43.01

Gene sequence:

>1137_bases
TTGAGTCATTCTGCCATATTGGTATTGGAAGATGGAACTGTATTTGAAGGTATCTCAATCGGTGCTGATGGTAGTTCTAT
CGGTGAGGTTGTTTTCAACACGTCAATGACGGGTTATCAGGAAATTTTAACAGATCCATCCTACGCACGCCAAATTGTTA
CATTAACCTACCCTCATATCGGAAATACCGGAACAAATAACGAAGACGAAGAGTCAACATCTATCCATGCCTGTGGTTTG
GTTATTCGTGATTTGCCGCTGCTTGCAAGCAATTTCCGTAATCAACTTGGGTTAAGTGATTATTTAAAAAAACATAATAT
TGTCGCTATTGCTGAAATTGATACACGTAAACTAACCCGTATTTTACGTGAAAAGGGTGCGCAAGCTGGTTGTATTGTTG
CGGATGAAAACCTCGATCAAGCGCTTGCTTTATCTCAAGCTAAAGCCTTTCCCGGTCTTAAAGGAATGGATTTGGCTAAG
GAAGTGAGTACTACTGAAGCCTATAATTGGGCACAGGGTAGCTGGACACTGACCGGCGGATTACCTGCAGATGCGACGGA
TTCGAAATATCATGTTGTCGCTTTTGATTATGGTGTTAAACGTAATATTTTACGTATGTTGGTTGACCGGGGCTGCCGCG
TAACGGTTGTGCCGGCACAAACTTCCGCAAGTGATGTATTAGCAATGAATCCTGATGGCATATTTCTGTCAAATGGCCCG
GGCGATCCGGAGCCTTGTACCTATGCGATTACCGCCATCCAAGAAATTCTAAAAACAGAGATTCCCGTCTTTGGTATCTG
TTTAGGCCATCAACTGCTTGCGTTAGCAAGTGGTGCTAAAACATCCAAAATGAAATTCGGTCATCATGGTGCCAACCATC
CGGTAAAAGATTTAGATCGTAATGTCGTTATGATTACCAGCCAAAATCATGGTTTTGCTGCTGATATATCATCATTACCG
GATAATTTGCGTGCCACGCATATTTCATTGTTTGATGGCTCACTGCAGGGAATGGCGCGTACTGATAAACCTGCATTTAG
TTTCCAAGGCCACCCAGAAGCAAGTCCGGGTCCGCATGATGCTGCGCCATTATTTAATCGCTTTATTGAGTTGATTGAAG
AGTACAAAAAAGCCTAG

Upstream 100 bases:

>100_bases
GTCGCCAATTTGCCAAAGTTTATGATTATTTGGTGGAAAAAAAACATTATTTTCCTCCAGTTATCAATAAATTTATTTTT
ATTTCCCTACGGAGGTTATT

Downstream 100 bases:

>100_bases
TTAATCAGAAAATAGAACACCGAATAGAAAGGTAAATTTCAGATGCCAAAACGTAATGACTTAAAAACTATCCTAATCAT
TGGCGCCGGACCGATTATTA

Product: carbamoyl-phosphate synthase, small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSHSAILVLEDGTVFEGISIGADGSSIGEVVFNTSMTGYQEILTDPSYARQIVTLTYPHIGNTGTNNEDEESTSIHACGL
VIRDLPLLASNFRNQLGLSDYLKKHNIVAIAEIDTRKLTRILREKGAQAGCIVADENLDQALALSQAKAFPGLKGMDLAK
EVSTTEAYNWAQGSWTLTGGLPADATDSKYHVVAFDYGVKRNILRMLVDRGCRVTVVPAQTSASDVLAMNPDGIFLSNGP
GDPEPCTYAITAIQEILKTEIPVFGICLGHQLLALASGAKTSKMKFGHHGANHPVKDLDRNVVMITSQNHGFAADISSLP
DNLRATHISLFDGSLQGMARTDKPAFSFQGHPEASPGPHDAAPLFNRFIELIEEYKKA

Sequences:

>Translated_378_residues
MSHSAILVLEDGTVFEGISIGADGSSIGEVVFNTSMTGYQEILTDPSYARQIVTLTYPHIGNTGTNNEDEESTSIHACGL
VIRDLPLLASNFRNQLGLSDYLKKHNIVAIAEIDTRKLTRILREKGAQAGCIVADENLDQALALSQAKAFPGLKGMDLAK
EVSTTEAYNWAQGSWTLTGGLPADATDSKYHVVAFDYGVKRNILRMLVDRGCRVTVVPAQTSASDVLAMNPDGIFLSNGP
GDPEPCTYAITAIQEILKTEIPVFGICLGHQLLALASGAKTSKMKFGHHGANHPVKDLDRNVVMITSQNHGFAADISSLP
DNLRATHISLFDGSLQGMARTDKPAFSFQGHPEASPGPHDAAPLFNRFIELIEEYKKA
>Mature_377_residues
SHSAILVLEDGTVFEGISIGADGSSIGEVVFNTSMTGYQEILTDPSYARQIVTLTYPHIGNTGTNNEDEESTSIHACGLV
IRDLPLLASNFRNQLGLSDYLKKHNIVAIAEIDTRKLTRILREKGAQAGCIVADENLDQALALSQAKAFPGLKGMDLAKE
VSTTEAYNWAQGSWTLTGGLPADATDSKYHVVAFDYGVKRNILRMLVDRGCRVTVVPAQTSASDVLAMNPDGIFLSNGPG
DPEPCTYAITAIQEILKTEIPVFGICLGHQLLALASGAKTSKMKFGHHGANHPVKDLDRNVVMITSQNHGFAADISSLPD
NLRATHISLFDGSLQGMARTDKPAFSFQGHPEASPGPHDAAPLFNRFIELIEEYKKA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=383, Percent_Identity=40.4699738903394, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI21361331, Length=387, Percent_Identity=35.9173126614987, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI169790915, Length=387, Percent_Identity=35.9173126614987, Blast_Score=217, Evalue=2e-56,
Organism=Escherichia coli, GI1786215, Length=379, Percent_Identity=78.1002638522427, Blast_Score=629, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193204318, Length=389, Percent_Identity=36.5038560411311, Blast_Score=228, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6324878, Length=389, Percent_Identity=41.1311053984576, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6322331, Length=393, Percent_Identity=37.1501272264631, Blast_Score=230, Evalue=3e-61,
Organism=Drosophila melanogaster, GI45555749, Length=392, Percent_Identity=39.030612244898, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24642586, Length=392, Percent_Identity=39.030612244898, Blast_Score=240, Evalue=1e-63,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40706; Mature: 40574

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSAILVLEDGTVFEGISIGADGSSIGEVVFNTSMTGYQEILTDPSYARQIVTLTYPHI
CCCCEEEEEECCCEEECEEECCCCCHHHHHEECCCCCHHHHHHCCHHHHCEEEEEECCCC
GNTGTNNEDEESTSIHACGLVIRDLPLLASNFRNQLGLSDYLKKHNIVAIAEIDTRKLTR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEEECCHHHHHH
ILREKGAQAGCIVADENLDQALALSQAKAFPGLKGMDLAKEVSTTEAYNWAQGSWTLTGG
HHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECC
LPADATDSKYHVVAFDYGVKRNILRMLVDRGCRVTVVPAQTSASDVLAMNPDGIFLSNGP
CCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEECCCC
GDPEPCTYAITAIQEILKTEIPVFGICLGHQLLALASGAKTSKMKFGHHGANHPVKDLDR
CCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHCCC
NVVMITSQNHGFAADISSLPDNLRATHISLFDGSLQGMARTDKPAFSFQGHPEASPGPHD
CEEEEEECCCCCEEEHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPLFNRFIELIEEYKKA
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHSAILVLEDGTVFEGISIGADGSSIGEVVFNTSMTGYQEILTDPSYARQIVTLTYPHI
CCCEEEEEECCCEEECEEECCCCCHHHHHEECCCCCHHHHHHCCHHHHCEEEEEECCCC
GNTGTNNEDEESTSIHACGLVIRDLPLLASNFRNQLGLSDYLKKHNIVAIAEIDTRKLTR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEEECCHHHHHH
ILREKGAQAGCIVADENLDQALALSQAKAFPGLKGMDLAKEVSTTEAYNWAQGSWTLTGG
HHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECC
LPADATDSKYHVVAFDYGVKRNILRMLVDRGCRVTVVPAQTSASDVLAMNPDGIFLSNGP
CCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEECCCC
GDPEPCTYAITAIQEILKTEIPVFGICLGHQLLALASGAKTSKMKFGHHGANHPVKDLDR
CCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHCCC
NVVMITSQNHGFAADISSLPDNLRATHISLFDGSLQGMARTDKPAFSFQGHPEASPGPHD
CEEEEEECCCCCEEEHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAPLFNRFIELIEEYKKA
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA