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The map label for this gene is nqrA

Identifier: 119944517

GI number: 119944517

Start: 941229

End: 942569

Strand: Direct

Name: nqrA

Synonym: Ping_0746

Alternate gene names: 119944517

Gene position: 941229-942569 (Clockwise)

Preceding gene: 119944516

Following gene: 119944518

Centisome position: 20.64

GC content: 41.69

Gene sequence:

>1341_bases
ATGATTACTATAAAAAAAGGACTGGATCTCCCTATTGCCGGCACACCAGAACAGGTTATTCATGATGGACCAAGCATCAC
TGAAATTGCGATACTGGGTGAAGAGTATGTAGGAATGCGTCCATTCATGGCAGTTAAAGTTGGCGATATCGTCAAAAAGG
GTCAAATTCTTTTTAGTGATAAAAGGAATTCCGGTGTGCATTTTACCTCTCCAGCATCCGGTACAGTGAAAGCAATTAAT
CGTGGGGCACAACGTGTTTTGCAGTCAGTTGTTATTGCTATAGAAGGCAAAGAAAGTATCTCTTTTCCTAAATATACAAG
TACAGAACTTAAAAACGTTGGCCGTGCTGAAATCGTTAAGAATTTAATCGATTCCGGTGCCTGGACGGCACTGCGTACTC
GCCCTTTCAGTAAAATACCTGCAGTTGATGCCGAGCCGGTTTCAATTTTTGTGACTGCAATGGATACCAATCCATTGGCA
GCTGATGCTGAATTAATTATTAATACCAATAAGCAGGCTTTTACTGACGGTTTAGCATTGTTAGAACAATTAACAGCTGG
CAAGGTTTATGTTTGTAAGGGTGAAACTAACCTGCCCAAATCTGAATCGGTAAATGTTGAAGAAAAGCTGTTTTCTGGTG
TTCACCCGGCAGGTTTAGCGGGAACGCATATTCATTTTATTGATCCTGTATCTGCTGTTAAACAGGTTTGGTCAATTAAC
TACCAGGATGTTATTGCCTTTGGTATGTTATTTACCACAGGTGAACTTTATACCAATAAAGTAATTTCACTTGCAGGCCC
GGCGGTGAAAAAACCGCGTTTATTACGTACCCATTATGGTGCCTCAATTAATCAGCTGACTAAAAATGAATTAATTGATG
ACGAAGTACGGGTGATTTCGGGTTCTGTTTTATGCGGTGTGACAGCAACAGCTGCGCATGCATACCTCGGACGCTACCAT
AATCAAATTTCTGTGTTAGCTGAAGGTTACGAGAAAGAGTTATTTGGTTGGGGTGTCCCCGGTAGTAAGAAACATTCTGT
CTCTAATGCTTTTATCTCTGCGTTCAATAGGGCAAAATCTTTTGCTTTTACAACCACCACAGGCGGTAGTAAGCGTGCAA
TGGTACCGATCGGTCAATATGAGCGCATTATGCCGCTGGATATTTTACCGACCAATTTGCTGCGTGACTTGATCGTTGGT
GATACTGAAGAAGCTCAGGCATTAGGCTGTTTAGAGTTAGATGAAGAGGATTTAGCACTATGTACTTATGTTTGCCCCGG
TAAATATGATTATGGTTCTGTGTTGCGTGCGAGCCTAAGCAAAATAGAGAAGGAAGGCTGA

Upstream 100 bases:

>100_bases
ACGTTTAATGATCGTTATTTTTTTAAAATCATGAAACGTGTAATGTTTTTATGCCGAAAGGCAACTAACATCCCATCCCT
TATACATAGTGCAAGAGAAT

Downstream 100 bases:

>100_bases
TAATGAATCTGAAGCATATAATTGAACAAATGGAACCGCATTTTGAGTCGGGAGGGCGTCATGCAAAATGGTACGCGCTG
TACGAAGCGGTCGCCACTTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MITIKKGLDLPIAGTPEQVIHDGPSITEIAILGEEYVGMRPFMAVKVGDIVKKGQILFSDKRNSGVHFTSPASGTVKAIN
RGAQRVLQSVVIAIEGKESISFPKYTSTELKNVGRAEIVKNLIDSGAWTALRTRPFSKIPAVDAEPVSIFVTAMDTNPLA
ADAELIINTNKQAFTDGLALLEQLTAGKVYVCKGETNLPKSESVNVEEKLFSGVHPAGLAGTHIHFIDPVSAVKQVWSIN
YQDVIAFGMLFTTGELYTNKVISLAGPAVKKPRLLRTHYGASINQLTKNELIDDEVRVISGSVLCGVTATAAHAYLGRYH
NQISVLAEGYEKELFGWGVPGSKKHSVSNAFISAFNRAKSFAFTTTTGGSKRAMVPIGQYERIMPLDILPTNLLRDLIVG
DTEEAQALGCLELDEEDLALCTYVCPGKYDYGSVLRASLSKIEKEG

Sequences:

>Translated_446_residues
MITIKKGLDLPIAGTPEQVIHDGPSITEIAILGEEYVGMRPFMAVKVGDIVKKGQILFSDKRNSGVHFTSPASGTVKAIN
RGAQRVLQSVVIAIEGKESISFPKYTSTELKNVGRAEIVKNLIDSGAWTALRTRPFSKIPAVDAEPVSIFVTAMDTNPLA
ADAELIINTNKQAFTDGLALLEQLTAGKVYVCKGETNLPKSESVNVEEKLFSGVHPAGLAGTHIHFIDPVSAVKQVWSIN
YQDVIAFGMLFTTGELYTNKVISLAGPAVKKPRLLRTHYGASINQLTKNELIDDEVRVISGSVLCGVTATAAHAYLGRYH
NQISVLAEGYEKELFGWGVPGSKKHSVSNAFISAFNRAKSFAFTTTTGGSKRAMVPIGQYERIMPLDILPTNLLRDLIVG
DTEEAQALGCLELDEEDLALCTYVCPGKYDYGSVLRASLSKIEKEG
>Mature_446_residues
MITIKKGLDLPIAGTPEQVIHDGPSITEIAILGEEYVGMRPFMAVKVGDIVKKGQILFSDKRNSGVHFTSPASGTVKAIN
RGAQRVLQSVVIAIEGKESISFPKYTSTELKNVGRAEIVKNLIDSGAWTALRTRPFSKIPAVDAEPVSIFVTAMDTNPLA
ADAELIINTNKQAFTDGLALLEQLTAGKVYVCKGETNLPKSESVNVEEKLFSGVHPAGLAGTHIHFIDPVSAVKQVWSIN
YQDVIAFGMLFTTGELYTNKVISLAGPAVKKPRLLRTHYGASINQLTKNELIDDEVRVISGSVLCGVTATAAHAYLGRYH
NQISVLAEGYEKELFGWGVPGSKKHSVSNAFISAFNRAKSFAFTTTTGGSKRAMVPIGQYERIMPLDILPTNLLRDLIVG
DTEEAQALGCLELDEEDLALCTYVCPGKYDYGSVLRASLSKIEKEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_PSYIN (A1SSY3)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942197.1
- STRING:   A1SSY3
- GeneID:   4623664
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0746
- eggNOG:   COG1726
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- BioCyc:   PING357804:PING_0746-MONOMER
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 48202; Mature: 48202

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLDLPIAGTPEQVIHDGPSITEIAILGEEYVGMRPFMAVKVGDIVKKGQILFSD
CEEECCCCCCCCCCCCHHHHCCCCCEEEEEEECHHHCCCCCEEEEEHHHHHHCCCEEEEC
KRNSGVHFTSPASGTVKAINRGAQRVLQSVVIAIEGKESISFPKYTSTELKNVGRAEIVK
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHCCCHHHHHH
NLIDSGAWTALRTRPFSKIPAVDAEPVSIFVTAMDTNPLAADAELIINTNKQAFTDGLAL
HHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHH
LEQLTAGKVYVCKGETNLPKSESVNVEEKLFSGVHPAGLAGTHIHFIDPVSAVKQVWSIN
HHHHCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHCCC
YQDVIAFGMLFTTGELYTNKVISLAGPAVKKPRLLRTHYGASINQLTKNELIDDEVRVIS
HHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHEE
GSVLCGVTATAAHAYLGRYHNQISVLAEGYEKELFGWGVPGSKKHSVSNAFISAFNRAKS
CCEEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCCCHHHHHHHHHHHHHHCC
FAFTTTTGGSKRAMVPIGQYERIMPLDILPTNLLRDLIVGDTEEAQALGCLELDEEDLAL
EEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCEECCCCCCEE
CTYVCPGKYDYGSVLRASLSKIEKEG
EEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLDLPIAGTPEQVIHDGPSITEIAILGEEYVGMRPFMAVKVGDIVKKGQILFSD
CEEECCCCCCCCCCCCHHHHCCCCCEEEEEEECHHHCCCCCEEEEEHHHHHHCCCEEEEC
KRNSGVHFTSPASGTVKAINRGAQRVLQSVVIAIEGKESISFPKYTSTELKNVGRAEIVK
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHCCCHHHHHH
NLIDSGAWTALRTRPFSKIPAVDAEPVSIFVTAMDTNPLAADAELIINTNKQAFTDGLAL
HHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHH
LEQLTAGKVYVCKGETNLPKSESVNVEEKLFSGVHPAGLAGTHIHFIDPVSAVKQVWSIN
HHHHCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHCCC
YQDVIAFGMLFTTGELYTNKVISLAGPAVKKPRLLRTHYGASINQLTKNELIDDEVRVIS
HHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHEE
GSVLCGVTATAAHAYLGRYHNQISVLAEGYEKELFGWGVPGSKKHSVSNAFISAFNRAKS
CCEEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCCCHHHHHHHHHHHHHHCC
FAFTTTTGGSKRAMVPIGQYERIMPLDILPTNLLRDLIVGDTEEAQALGCLELDEEDLAL
EEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCEECCCCCCEE
CTYVCPGKYDYGSVLRASLSKIEKEG
EEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA