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The map label for this gene is tdk [H]

Identifier: 119944457

GI number: 119944457

Start: 871901

End: 872479

Strand: Reverse

Name: tdk [H]

Synonym: Ping_0685

Alternate gene names: 119944457

Gene position: 872479-871901 (Counterclockwise)

Preceding gene: 119944459

Following gene: 119944456

Centisome position: 19.13

GC content: 43.7

Gene sequence:

>579_bases
GTGGCGCAGCTCTATTTCTATCACTCAACCATGAATGCCGGTAAATCAACCTCTCTATTGCAATCCGCCTATAACTACCG
GGAGCGTGGCATGCAGTGCTTGGTCATGACACCCAGCATTGATAATCGCGCCGGCGTGGGGAAAGTCGCCTCGAGAATTG
GGCTGGAGTGTGATGCACAACTGTTTTCTGGTGAGGATAATTTAGCAAAAATGATAGAGATCGCCCATCGGGTAGAGCAT
CAGCATTGTATTCTAATTGATGAAGCACAATTTCTCACTAAAGAGCAGGTTAAACAGTTAACCTGGATCGTGGATAAGTT
ATCAATTCCTATTTTGTGTTACGGCATTAAAACCGATTTTCAAGGTGAATTATTTACCGGTAGCCACTATCTGCTGGCTT
GGGCTGATAAATTGGTTGAGTTAAAAACCATCTGCCACTGTGGCCGTAAAGCTAATATGGTGTTACGACTGGATAAACAG
GGTAAGCCAATCACCAAAGGAGCACAGGTTGAAATTGGCGGTAATGAAAGCTATGAATCCGTTTGCAGGAAACACTTTCG
CATTTTTATATGGGATTAA

Upstream 100 bases:

>100_bases
ATTAATTGCCCATCAGCACTGCGAAATAAACAATCAATTTAACTAACAGAATGTTATTATCAGCTCCCCCAATTTCTCTC
TCCCAATAAGGTACCTCTCT

Downstream 100 bases:

>100_bases
ATTTCTTTGATTTAAGCCAAATACCAGCAGGTTATCTTCATCATTTAGGACGAATCCTTCAACCGATAACAGCGAGCCTC
TCTTAATAAAAGACTTAAAA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAQLYFYHSTMNAGKSTSLLQSAYNYRERGMQCLVMTPSIDNRAGVGKVASRIGLECDAQLFSGEDNLAKMIEIAHRVEH
QHCILIDEAQFLTKEQVKQLTWIVDKLSIPILCYGIKTDFQGELFTGSHYLLAWADKLVELKTICHCGRKANMVLRLDKQ
GKPITKGAQVEIGGNESYESVCRKHFRIFIWD

Sequences:

>Translated_192_residues
MAQLYFYHSTMNAGKSTSLLQSAYNYRERGMQCLVMTPSIDNRAGVGKVASRIGLECDAQLFSGEDNLAKMIEIAHRVEH
QHCILIDEAQFLTKEQVKQLTWIVDKLSIPILCYGIKTDFQGELFTGSHYLLAWADKLVELKTICHCGRKANMVLRLDKQ
GKPITKGAQVEIGGNESYESVCRKHFRIFIWD
>Mature_191_residues
AQLYFYHSTMNAGKSTSLLQSAYNYRERGMQCLVMTPSIDNRAGVGKVASRIGLECDAQLFSGEDNLAKMIEIAHRVEHQ
HCILIDEAQFLTKEQVKQLTWIVDKLSIPILCYGIKTDFQGELFTGSHYLLAWADKLVELKTICHCGRKANMVLRLDKQG
KPITKGAQVEIGGNESYESVCRKHFRIFIWD

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=187, Percent_Identity=63.6363636363636, Blast_Score=260, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21819; Mature: 21687

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFYHSTMNAGKSTSLLQSAYNYRERGMQCLVMTPSIDNRAGVGKVASRIGLECDAQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHH
LFSGEDNLAKMIEIAHRVEHQHCILIDEAQFLTKEQVKQLTWIVDKLSIPILCYGIKTDF
EECCCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
QGELFTGSHYLLAWADKLVELKTICHCGRKANMVLRLDKQGKPITKGAQVEIGGNESYES
CCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHH
VCRKHFRIFIWD
HHHHCCEEEEEC
>Mature Secondary Structure 
AQLYFYHSTMNAGKSTSLLQSAYNYRERGMQCLVMTPSIDNRAGVGKVASRIGLECDAQ
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHH
LFSGEDNLAKMIEIAHRVEHQHCILIDEAQFLTKEQVKQLTWIVDKLSIPILCYGIKTDF
EECCCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
QGELFTGSHYLLAWADKLVELKTICHCGRKANMVLRLDKQGKPITKGAQVEIGGNESYES
CCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHH
VCRKHFRIFIWD
HHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]