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The map label for this gene is paaX [H]

Identifier: 119944433

GI number: 119944433

Start: 847021

End: 847878

Strand: Direct

Name: paaX [H]

Synonym: Ping_0661

Alternate gene names: 119944433

Gene position: 847021-847878 (Clockwise)

Preceding gene: 119944432

Following gene: 119944434

Centisome position: 18.58

GC content: 36.71

Gene sequence:

>858_bases
ATGACTTTCCTGGGTGATTATCTTTGCCATAGTGACAGTGCAATAGGGATGAGCAGCTTAATAAACTTCTTTGAATCTTT
AGGGTTCAATCAACGTTTTGTACGCTCATCCCTGTTTAGATTAAAACAAGACGGTTGGGTTGATGCAAAAAAAGTAGGCA
GGAAAAGCTATTATTATATGACGCCTGAGCGCTTTGATGAAATAAGAGAGGCGAACAAAAAAATTTATAATACCGAAAAG
CCGGCCTGGAATGGAAGATGGAATTTTATTCATATTCCCTCATCTACGATCACTGAATCAAACCTTAAAGGCAAAGAACT
GGCTAAATATGGTTTTGGAATACTCAATAAAGGAATGTATATTCAGGCAGATCAAGGACAAGCATTGCAACCTAGCTTTA
AACGGATCTTAAGTAAATGTTCAGATGCAACTATTTTGACTGGCGCAGAGCTTGTTTCATGCAAGGAAAAAAACAAAAGT
AAATTTGTTTCTGATACTTGGAATTTAGATAAAATCAATGACGATTACGGCGCTTTTGTCAATATGTTTGACCCAATAGA
GTTAATGATACAAGAGGCAGGCAGTGACGCCTTAGATAATGAAGATTGTTTCAAATTACGCCTTCTCCTGATCCATTTTT
ATAGACGTATTATTATTCGTGATCCTCTGCTTCCCGATGAATTCTTGCCTCATAATTGGAGTGGACGGCGTGCGCAAGAA
ATTACAATCAATATATACCAAAAAATTCATTTACAAGCCAAAGCTCATATAACAGAGCATGGTGAAACAATTGACGGGCT
ATTGCCTTTACTTGCATCGGATTATTATTCTCGTTTTAATGGTCTGGGTAATATTTAA

Upstream 100 bases:

>100_bases
GACTTAAAAATAATTATATTGAGGTTTTTTGAAAACAAAATTAAACGAATTTTTCACTTTAGCAATAGAGCATAATTATA
TTAGTGGAAGATCCTTAGTG

Downstream 100 bases:

>100_bases
TAATACAAAGGATTTAGCATGGCAATATATAAAATTGATGGAGTAACACCGGTCATTCACCCTAGCAGTTTTGTGCACCC
CAGTGCTGATATTATTGGTG

Product: PaaX domain-containing protein, C- domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTFLGDYLCHSDSAIGMSSLINFFESLGFNQRFVRSSLFRLKQDGWVDAKKVGRKSYYYMTPERFDEIREANKKIYNTEK
PAWNGRWNFIHIPSSTITESNLKGKELAKYGFGILNKGMYIQADQGQALQPSFKRILSKCSDATILTGAELVSCKEKNKS
KFVSDTWNLDKINDDYGAFVNMFDPIELMIQEAGSDALDNEDCFKLRLLLIHFYRRIIIRDPLLPDEFLPHNWSGRRAQE
ITINIYQKIHLQAKAHITEHGETIDGLLPLLASDYYSRFNGLGNI

Sequences:

>Translated_285_residues
MTFLGDYLCHSDSAIGMSSLINFFESLGFNQRFVRSSLFRLKQDGWVDAKKVGRKSYYYMTPERFDEIREANKKIYNTEK
PAWNGRWNFIHIPSSTITESNLKGKELAKYGFGILNKGMYIQADQGQALQPSFKRILSKCSDATILTGAELVSCKEKNKS
KFVSDTWNLDKINDDYGAFVNMFDPIELMIQEAGSDALDNEDCFKLRLLLIHFYRRIIIRDPLLPDEFLPHNWSGRRAQE
ITINIYQKIHLQAKAHITEHGETIDGLLPLLASDYYSRFNGLGNI
>Mature_284_residues
TFLGDYLCHSDSAIGMSSLINFFESLGFNQRFVRSSLFRLKQDGWVDAKKVGRKSYYYMTPERFDEIREANKKIYNTEKP
AWNGRWNFIHIPSSTITESNLKGKELAKYGFGILNKGMYIQADQGQALQPSFKRILSKCSDATILTGAELVSCKEKNKSK
FVSDTWNLDKINDDYGAFVNMFDPIELMIQEAGSDALDNEDCFKLRLLLIHFYRRIIIRDPLLPDEFLPHNWSGRRAQEI
TINIYQKIHLQAKAHITEHGETIDGLLPLLASDYYSRFNGLGNI

Specific function: Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons. Binds the consensus sequence 5'- WWTRTGATTCGYGWT-3'. Binding of paaX is specifically inhibited by phenylacetyl-coenzyme A [H]

COG id: COG3327

COG function: function code K; Phenylacetic acid-responsive transcriptional repressor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787666, Length=286, Percent_Identity=37.0629370629371, Blast_Score=197, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012906
- InterPro:   IPR013225
- InterPro:   IPR011965 [H]

Pfam domain/function: PF07848 PaaX; PF08223 PaaX_C [H]

EC number: NA

Molecular weight: Translated: 32819; Mature: 32688

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLGDYLCHSDSAIGMSSLINFFESLGFNQRFVRSSLFRLKQDGWVDAKKVGRKSYYYM
CCCCHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEE
TPERFDEIREANKKIYNTEKPAWNGRWNFIHIPSSTITESNLKGKELAKYGFGILNKGMY
CHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEE
IQADQGQALQPSFKRILSKCSDATILTGAELVSCKEKNKSKFVSDTWNLDKINDDYGAFV
EEECCCCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHH
NMFDPIELMIQEAGSDALDNEDCFKLRLLLIHFYRRIIIRDPLLPDEFLPHNWSGRRAQE
HHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEHE
ITINIYQKIHLQAKAHITEHGETIDGLLPLLASDYYSRFNGLGNI
EEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TFLGDYLCHSDSAIGMSSLINFFESLGFNQRFVRSSLFRLKQDGWVDAKKVGRKSYYYM
CCCHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEE
TPERFDEIREANKKIYNTEKPAWNGRWNFIHIPSSTITESNLKGKELAKYGFGILNKGMY
CHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEE
IQADQGQALQPSFKRILSKCSDATILTGAELVSCKEKNKSKFVSDTWNLDKINDDYGAFV
EEECCCCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHH
NMFDPIELMIQEAGSDALDNEDCFKLRLLLIHFYRRIIIRDPLLPDEFLPHNWSGRRAQE
HHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEHE
ITINIYQKIHLQAKAHITEHGETIDGLLPLLASDYYSRFNGLGNI
EEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]