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The map label for this gene is panC

Identifier: 119944352

GI number: 119944352

Start: 758404

End: 759273

Strand: Reverse

Name: panC

Synonym: Ping_0579

Alternate gene names: 119944352

Gene position: 759273-758404 (Counterclockwise)

Preceding gene: 119944353

Following gene: 119944351

Centisome position: 16.65

GC content: 39.66

Gene sequence:

>870_bases
ATGCTTATTATTGATAATCCACAGCAACTACGTGAAAAGATAAAACAACTCAAACAGCAAGGGTCTGAAATTGCTTTTGT
GCCTACCATGGGAAATTTACATGAGGGGCATTTAACTCTAGTGCAGGCTGGCCAGAAAAAAGCTGCCGTGGTTATTGTGA
GTATTTTTATTAACCCGATGCAGTTTAATAATGCACAGGATTTGCTAAATTATCCAAAAACAATGGCGCAAGATTGTGAA
AAACTGGCGGCGGCTGGGGTAAATATTATTTTTACGCCCGCAGCGAGCAGCATTTATCCAAATGGTTTGAATGCTCAAAC
CTATGTTGAGGTGCCCCTTTTATCTAATTGTTTAGAAGGCGAACTTCGCCCAGGACATTTCCGCGGCATGAGCACCATAG
TGAATAAATTATTTAACCTTGTTCAACCTGATTATGCCTGTTTTGGTGAAAAAGACTTTCAGCAGTTAGCCATTGTCAAA
CAGATGGTAAGCGATTTAGGCATGCCCATTGAGATAATTCCGGTTGCGACTATGCGCGAAAAAAATGGCCTGGCGATGAG
TTCTCGCAATGGTAAACTGAGCAGCTTAGAAAAACAAAAAGCGCCTCTTTTAGCAAAAGTGATGAATCAATTAGCTGTTG
ATGTGCAAGCACAGAAAACTGAACTTTCAATATTAATAGATGATGCCTCAATCATCCTTAATAACGCCGGTTTTAATACC
GATGCTATCCATATTGTCGATGCACAAACATTACAGGCGGTGAATTGCCATAGTAAGGAAGCGGTTATTTTAATGGCGGC
TTTTTTAGGGGAAACACGTTTAATTGATAATAAAGTAGTCATCCTGAATCATTCGGCAACAAAAATTTAA

Upstream 100 bases:

>100_bases
ATATTCGCCAGGCGGTAACGCTTTATATAGATCAAGTTGAAAGCAGACAATTCCCGTCTGCTGAACACAGTTTTTATTAA
GTATATTGGCAGATAAAAAC

Downstream 100 bases:

>100_bases
GTGTAATTTCTTGGTGTTGCGTCGACTTTTAATCAATACGCCATCTTTCCTTGATGTTATAAATTTGACTTTCATCAAAG
CGCATTATAACTCTACAGAT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLIIDNPQQLREKIKQLKQQGSEIAFVPTMGNLHEGHLTLVQAGQKKAAVVIVSIFINPMQFNNAQDLLNYPKTMAQDCE
KLAAAGVNIIFTPAASSIYPNGLNAQTYVEVPLLSNCLEGELRPGHFRGMSTIVNKLFNLVQPDYACFGEKDFQQLAIVK
QMVSDLGMPIEIIPVATMREKNGLAMSSRNGKLSSLEKQKAPLLAKVMNQLAVDVQAQKTELSILIDDASIILNNAGFNT
DAIHIVDAQTLQAVNCHSKEAVILMAAFLGETRLIDNKVVILNHSATKI

Sequences:

>Translated_289_residues
MLIIDNPQQLREKIKQLKQQGSEIAFVPTMGNLHEGHLTLVQAGQKKAAVVIVSIFINPMQFNNAQDLLNYPKTMAQDCE
KLAAAGVNIIFTPAASSIYPNGLNAQTYVEVPLLSNCLEGELRPGHFRGMSTIVNKLFNLVQPDYACFGEKDFQQLAIVK
QMVSDLGMPIEIIPVATMREKNGLAMSSRNGKLSSLEKQKAPLLAKVMNQLAVDVQAQKTELSILIDDASIILNNAGFNT
DAIHIVDAQTLQAVNCHSKEAVILMAAFLGETRLIDNKVVILNHSATKI
>Mature_289_residues
MLIIDNPQQLREKIKQLKQQGSEIAFVPTMGNLHEGHLTLVQAGQKKAAVVIVSIFINPMQFNNAQDLLNYPKTMAQDCE
KLAAAGVNIIFTPAASSIYPNGLNAQTYVEVPLLSNCLEGELRPGHFRGMSTIVNKLFNLVQPDYACFGEKDFQQLAIVK
QMVSDLGMPIEIIPVATMREKNGLAMSSRNGKLSSLEKQKAPLLAKVMNQLAVDVQAQKTELSILIDDASIILNNAGFNT
DAIHIVDAQTLQAVNCHSKEAVILMAAFLGETRLIDNKVVILNHSATKI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=282, Percent_Identity=54.9645390070922, Blast_Score=325, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6322046, Length=302, Percent_Identity=33.4437086092715, Blast_Score=151, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_PSYIN (A1SSG8)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942032.1
- ProteinModelPortal:   A1SSG8
- SMR:   A1SSG8
- STRING:   A1SSG8
- GeneID:   4624134
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0579
- eggNOG:   COG0414
- HOGENOM:   HBG428839
- OMA:   DEAHDAK
- PhylomeDB:   A1SSG8
- BioCyc:   PING357804:PING_0579-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 31603; Mature: 31603

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: ACT_SITE 37-37 BINDING 61-61 BINDING 61-61 BINDING 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIDNPQQLREKIKQLKQQGSEIAFVPTMGNLHEGHLTLVQAGQKKAAVVIVSIFINPM
CEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEECCC
QFNNAQDLLNYPKTMAQDCEKLAAAGVNIIFTPAASSIYPNGLNAQTYVEVPLLSNCLEG
CCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECHHHHHHHCC
ELRPGHFRGMSTIVNKLFNLVQPDYACFGEKDFQQLAIVKQMVSDLGMPIEIIPVATMRE
CCCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
KNGLAMSSRNGKLSSLEKQKAPLLAKVMNQLAVDVQAQKTELSILIDDASIILNNAGFNT
CCCCEEECCCCCHHHHHHHCCHHHHHHHHHHHHCCEECCEEEEEEEECCEEEEECCCCCC
DAIHIVDAQTLQAVNCHSKEAVILMAAFLGETRLIDNKVVILNHSATKI
CEEEEEEHHHHHHHCCCCCCHHHHHHHHHCCCEEECCEEEEEECCCCCC
>Mature Secondary Structure
MLIIDNPQQLREKIKQLKQQGSEIAFVPTMGNLHEGHLTLVQAGQKKAAVVIVSIFINPM
CEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEECCC
QFNNAQDLLNYPKTMAQDCEKLAAAGVNIIFTPAASSIYPNGLNAQTYVEVPLLSNCLEG
CCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECHHHHHHHCC
ELRPGHFRGMSTIVNKLFNLVQPDYACFGEKDFQQLAIVKQMVSDLGMPIEIIPVATMRE
CCCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
KNGLAMSSRNGKLSSLEKQKAPLLAKVMNQLAVDVQAQKTELSILIDDASIILNNAGFNT
CCCCEEECCCCCHHHHHHHCCHHHHHHHHHHHHCCEECCEEEEEEEECCEEEEECCCCCC
DAIHIVDAQTLQAVNCHSKEAVILMAAFLGETRLIDNKVVILNHSATKI
CEEEEEEHHHHHHHCCCCCCHHHHHHHHHCCCEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA