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The map label for this gene is mocR [H]

Identifier: 119944342

GI number: 119944342

Start: 747679

End: 749178

Strand: Reverse

Name: mocR [H]

Synonym: Ping_0569

Alternate gene names: 119944342

Gene position: 749178-747679 (Counterclockwise)

Preceding gene: 119944351

Following gene: 119944341

Centisome position: 16.43

GC content: 46.07

Gene sequence:

>1500_bases
TTGGAATCATTAAGTAGCGATCTATTATTACAACGGTTTGCAGAGCAGTCCGATGAGAAACTTTATAAACGTCTGTATAA
CGCGATTCGCAGCACTATTCTAGAGGGTAGTTTGCTGCCGTCGAGCCGCTTACCTGCAACGCGTGATCTGGCAAAGGTAC
TGCAATTATCACGTAATACCGTCCTGACGGTTTACGATCAATTACAGGCAGAAGGTTATTTATTAACGCGCGCCGGCAGT
GGTACTTTTGTGGCGGAAACCCTGCCGGATAGTTACTTATCCAGCGAAAGCGTGCCCGATCAACTATCAATTAGCAGCCG
ACAAATTAAGCTATCCCAACGAGGTTGCACACTGCTTGGAGATGCCAGCGCAAGCCCTGAACAATGGGGTGCATTTATCC
CGGGGGTACCTGATGTTACGGCCTTTCCCCATCATTTATTCAGCAAAATTCAGGCACGCATTAATCGCCGTCCTCCGCCG
CAGGAGCTAAGCTACAGCAATCAGGGAGGCCACCCCGAATTACGTCATGCATTGGTTGATTATCTGCGCGTAGCACGTTC
AGTACGTTGCAGCGCGGATCAAATTCTGATTACCGAAGGAATTCACCAGGCCATTGATCTGGTCACCCGTCTATTATGTG
ATCCCGGGGATACAGTCTGGCTTGAAGAGCCTGGGTATTGGGGAATACGCAATATTCTGCACATGAATGAAGTTAATATT
CACCCGCTTCCGGTGGATAAATCAGGTCTGGTGTTACCTAAAAAAATAGAAAAAAAACCCAGTTTAACCTTCGTGACCCC
CTCCCATCAATATCCATTAGGGTCGGTAATGAGCCTCAGACGCAGACAGCGTTTGCTTTTGATGGCGGCAAAAACAGGAA
GTTGGATTATTGAGGACGATTACGATAGTGAGTTTCGCTTCTCCGGTCAGCCTATTCCCGCCCTGCAGGGCTTGCAATCC
GATGCACCGGTGATCTACATAGGCACTTTTAGTAAAACCTTATACCCGGCATTACGTATTGGCTATGTAGTCATACCCAA
ATCATTAATGAAACCATTAAAAACCGCCCATTCAGAATTATATCGCGGTGGCCACCTTCTGATTCAAAAAGCATTAGGAC
AGTTTATTCAAGAAGGTCACTACGCTGCCCATATTCGCAGGATGCGTTTACTCTATGCAAAACGCCGCGCCTTTTTGGTT
GAGTTAATTGAATCTCATTTAGGCAAAACAGCGCTAAGTGAATTCAATAGCAATGCAGGTTTACATCTCATTTTAAATCT
GCCGGATAACAGTAATGATGTCGCTATCAGTGAGGCCGCCAATGCACAGGGAGTGTTGGTCAGGCCGTTATCCCGTTATT
ACATGTTAGACAATGTACGACAAGGCTTACTGATGGGTTTTGCTTGTGTTCCTGAAGAGCAAATGGCTAAAGCCTTCACC
CTATTATTGGATTGTATACGCAACGCAAGCAGCAAGTTTGAGATAAACACAACACACTAA

Upstream 100 bases:

>100_bases
CAAGCTAGTATGTTAATAAAGTGTTACAACCGAGGGGATGTATTTATACGGCATGTGGTTGTATAATCTAGTACCAATTG
TTATTAATTAAGGGGGCCAA

Downstream 100 bases:

>100_bases
GCGATGAGATAGAGTTCACTGAACTTAAACGCTTAAACGAAAAAATTCCTGCTGACGTTAGTCAACAGGGATTTTTCTGG
ATTTAATTGCACAGCTTGTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MESLSSDLLLQRFAEQSDEKLYKRLYNAIRSTILEGSLLPSSRLPATRDLAKVLQLSRNTVLTVYDQLQAEGYLLTRAGS
GTFVAETLPDSYLSSESVPDQLSISSRQIKLSQRGCTLLGDASASPEQWGAFIPGVPDVTAFPHHLFSKIQARINRRPPP
QELSYSNQGGHPELRHALVDYLRVARSVRCSADQILITEGIHQAIDLVTRLLCDPGDTVWLEEPGYWGIRNILHMNEVNI
HPLPVDKSGLVLPKKIEKKPSLTFVTPSHQYPLGSVMSLRRRQRLLLMAAKTGSWIIEDDYDSEFRFSGQPIPALQGLQS
DAPVIYIGTFSKTLYPALRIGYVVIPKSLMKPLKTAHSELYRGGHLLIQKALGQFIQEGHYAAHIRRMRLLYAKRRAFLV
ELIESHLGKTALSEFNSNAGLHLILNLPDNSNDVAISEAANAQGVLVRPLSRYYMLDNVRQGLLMGFACVPEEQMAKAFT
LLLDCIRNASSKFEINTTH

Sequences:

>Translated_499_residues
MESLSSDLLLQRFAEQSDEKLYKRLYNAIRSTILEGSLLPSSRLPATRDLAKVLQLSRNTVLTVYDQLQAEGYLLTRAGS
GTFVAETLPDSYLSSESVPDQLSISSRQIKLSQRGCTLLGDASASPEQWGAFIPGVPDVTAFPHHLFSKIQARINRRPPP
QELSYSNQGGHPELRHALVDYLRVARSVRCSADQILITEGIHQAIDLVTRLLCDPGDTVWLEEPGYWGIRNILHMNEVNI
HPLPVDKSGLVLPKKIEKKPSLTFVTPSHQYPLGSVMSLRRRQRLLLMAAKTGSWIIEDDYDSEFRFSGQPIPALQGLQS
DAPVIYIGTFSKTLYPALRIGYVVIPKSLMKPLKTAHSELYRGGHLLIQKALGQFIQEGHYAAHIRRMRLLYAKRRAFLV
ELIESHLGKTALSEFNSNAGLHLILNLPDNSNDVAISEAANAQGVLVRPLSRYYMLDNVRQGLLMGFACVPEEQMAKAFT
LLLDCIRNASSKFEINTTH
>Mature_499_residues
MESLSSDLLLQRFAEQSDEKLYKRLYNAIRSTILEGSLLPSSRLPATRDLAKVLQLSRNTVLTVYDQLQAEGYLLTRAGS
GTFVAETLPDSYLSSESVPDQLSISSRQIKLSQRGCTLLGDASASPEQWGAFIPGVPDVTAFPHHLFSKIQARINRRPPP
QELSYSNQGGHPELRHALVDYLRVARSVRCSADQILITEGIHQAIDLVTRLLCDPGDTVWLEEPGYWGIRNILHMNEVNI
HPLPVDKSGLVLPKKIEKKPSLTFVTPSHQYPLGSVMSLRRRQRLLLMAAKTGSWIIEDDYDSEFRFSGQPIPALQGLQS
DAPVIYIGTFSKTLYPALRIGYVVIPKSLMKPLKTAHSELYRGGHLLIQKALGQFIQEGHYAAHIRRMRLLYAKRRAFLV
ELIESHLGKTALSEFNSNAGLHLILNLPDNSNDVAISEAANAQGVLVRPLSRYYMLDNVRQGLLMGFACVPEEQMAKAFT
LLLDCIRNASSKFEINTTH

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=360, Percent_Identity=26.9444444444444, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI33469970, Length=360, Percent_Identity=26.9444444444444, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4507369, Length=162, Percent_Identity=30.2469135802469, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787710, Length=447, Percent_Identity=25.7270693512304, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1790797, Length=422, Percent_Identity=25.8293838862559, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321236, Length=312, Percent_Identity=22.1153846153846, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55761; Mature: 55761

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLSSDLLLQRFAEQSDEKLYKRLYNAIRSTILEGSLLPSSRLPATRDLAKVLQLSRNT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
VLTVYDQLQAEGYLLTRAGSGTFVAETLPDSYLSSESVPDQLSISSRQIKLSQRGCTLLG
EEEEHHHHCCCCEEEEECCCCCEEEHHCCHHHHCCCCCCCCCCCCCCEEEECCCCCEEEE
DASASPEQWGAFIPGVPDVTAFPHHLFSKIQARINRRPPPQELSYSNQGGHPELRHALVD
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHH
YLRVARSVRCSADQILITEGIHQAIDLVTRLLCDPGDTVWLEEPGYWGIRNILHMNEVNI
HHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCC
HPLPVDKSGLVLPKKIEKKPSLTFVTPSHQYPLGSVMSLRRRQRLLLMAAKTGSWIIEDD
EECCCCCCCCCCCHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHEEEEEECCCCEEEECC
YDSEFRFSGQPIPALQGLQSDAPVIYIGTFSKTLYPALRIGYVVIPKSLMKPLKTAHSEL
CCCCEEECCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEEECHHHHHHHHHHHHHH
YRGGHLLIQKALGQFIQEGHYAAHIRRMRLLYAKRRAFLVELIESHLGKTALSEFNSNAG
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
LHLILNLPDNSNDVAISEAANAQGVLVRPLSRYYMLDNVRQGLLMGFACVPEEQMAKAFT
EEEEEECCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LLLDCIRNASSKFEINTTH
HHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MESLSSDLLLQRFAEQSDEKLYKRLYNAIRSTILEGSLLPSSRLPATRDLAKVLQLSRNT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
VLTVYDQLQAEGYLLTRAGSGTFVAETLPDSYLSSESVPDQLSISSRQIKLSQRGCTLLG
EEEEHHHHCCCCEEEEECCCCCEEEHHCCHHHHCCCCCCCCCCCCCCEEEECCCCCEEEE
DASASPEQWGAFIPGVPDVTAFPHHLFSKIQARINRRPPPQELSYSNQGGHPELRHALVD
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHH
YLRVARSVRCSADQILITEGIHQAIDLVTRLLCDPGDTVWLEEPGYWGIRNILHMNEVNI
HHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCC
HPLPVDKSGLVLPKKIEKKPSLTFVTPSHQYPLGSVMSLRRRQRLLLMAAKTGSWIIEDD
EECCCCCCCCCCCHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHEEEEEECCCCEEEECC
YDSEFRFSGQPIPALQGLQSDAPVIYIGTFSKTLYPALRIGYVVIPKSLMKPLKTAHSEL
CCCCEEECCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEEECHHHHHHHHHHHHHH
YRGGHLLIQKALGQFIQEGHYAAHIRRMRLLYAKRRAFLVELIESHLGKTALSEFNSNAG
HCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
LHLILNLPDNSNDVAISEAANAQGVLVRPLSRYYMLDNVRQGLLMGFACVPEEQMAKAFT
EEEEEECCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LLLDCIRNASSKFEINTTH
HHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]