Click here to switch to the map view.

The map label for this gene is pilE [H]

Identifier: 119944253

GI number: 119944253

Start: 603758

End: 604204

Strand: Direct

Name: pilE [H]

Synonym: Ping_0477

Alternate gene names: 119944253

Gene position: 603758-604204 (Clockwise)

Preceding gene: 119944252

Following gene: 119944254

Centisome position: 13.24

GC content: 40.27

Gene sequence:

>447_bases
ATGAAAAAAATACAATCGGGTTTTACATTAATAGAGCTGTTAATTGTTATTGCGATTATCGGTATTCTGGCGGCTGTGGC
GTTACCGACTTATAATACTTATACGAAAAAAGCGCAATTTTCTCAATTAATTGCGGCTGTTGGACCTATGAAAACTGCCG
TAGAAATTTGTGCTCAGCTAAATGCAACAACTGATGCTAATTTTTCAACCAACTGTATTCAAAATATAGATGATGTGCCT
AATACTTATACTATTAAGGGGGCTGCTGTAACCGCGACAGTAGCAAAGCATGCGAATGCTACTGCGGTTGCTGATAGCGA
TCTATATGTGTCAGCATCAAATGCAAATGCTATCGGTAGCTTAGGGGCTGCTTCTCTGTATTCTCTTGCGGCTGAGTGGG
AGCCTGATGGTTCAGTAACTTGGACTGCTGAAGAAGTTATAAACTAG

Upstream 100 bases:

>100_bases
CTTTTTTAATTTTTAATTATTAACCGTTACGCATTTTACGTTAATAAGAAAAAGGATAAAAGTTTAAAATAAACCAGTCT
TAATTATTAAGGAAGATACA

Downstream 100 bases:

>100_bases
TTAATGGCAACTCATCATATCAGCGGCCAGGCTTTTAGCCTGGCCGCTTTTTTTTACTCCCCTTTAATAAACTTCAGCAG
TTAACCAGCGCAGTTCTGCA

Product: prepilin-type cleavage/methylation

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKKIQSGFTLIELLIVIAIIGILAAVALPTYNTYTKKAQFSQLIAAVGPMKTAVEICAQLNATTDANFSTNCIQNIDDVP
NTYTIKGAAVTATVAKHANATAVADSDLYVSASNANAIGSLGAASLYSLAAEWEPDGSVTWTAEEVIN

Sequences:

>Translated_148_residues
MKKIQSGFTLIELLIVIAIIGILAAVALPTYNTYTKKAQFSQLIAAVGPMKTAVEICAQLNATTDANFSTNCIQNIDDVP
NTYTIKGAAVTATVAKHANATAVADSDLYVSASNANAIGSLGAASLYSLAAEWEPDGSVTWTAEEVIN
>Mature_148_residues
MKKIQSGFTLIELLIVIAIIGILAAVALPTYNTYTKKAQFSQLIAAVGPMKTAVEICAQLNATTDANFSTNCIQNIDDVP
NTYTIKGAAVTATVAKHANATAVADSDLYVSASNANAIGSLGAASLYSLAAEWEPDGSVTWTAEEVIN

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=54, Percent_Identity=50, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 15412; Mature: 15412

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIQSGFTLIELLIVIAIIGILAAVALPTYNTYTKKAQFSQLIAAVGPMKTAVEICAQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHC
NATTDANFSTNCIQNIDDVPNTYTIKGAAVTATVAKHANATAVADSDLYVSASNANAIGS
CCCCCCCCCHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCEEECCCEEEECCCCCCHHH
LGAASLYSLAAEWEPDGSVTWTAEEVIN
HHHHHHHHHHHCCCCCCCEEEEHHHHCC
>Mature Secondary Structure
MKKIQSGFTLIELLIVIAIIGILAAVALPTYNTYTKKAQFSQLIAAVGPMKTAVEICAQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHC
NATTDANFSTNCIQNIDDVPNTYTIKGAAVTATVAKHANATAVADSDLYVSASNANAIGS
CCCCCCCCCHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCEEECCCEEEECCCCCCHHH
LGAASLYSLAAEWEPDGSVTWTAEEVIN
HHHHHHHHHHHCCCCCCCEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 9515697 [H]