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The map label for this gene is atpA1

Identifier: 119944246

GI number: 119944246

Start: 592449

End: 594008

Strand: Direct

Name: atpA1

Synonym: Ping_0470

Alternate gene names: 119944246

Gene position: 592449-594008 (Clockwise)

Preceding gene: 119944245

Following gene: 119944247

Centisome position: 12.99

GC content: 48.4

Gene sequence:

>1560_bases
ATGACTGATTTACAACAGGTAGTTGCGCATTCTTTTGCGGCATTAGCAGCTAGCCGCACAACTTTTCGAGCGCAGCTAAA
AGCGCGTGAAATTGGCATCATCAGCAGTGTTTCATTTGGTGTTGCTCAAGTATCCGGACTTGCAAATGTCGCCTCTGAGG
AAGTACTTAAATTTTCCGGTGATATTTACGGCATCGCTTTTAATGTCGATCAAGATAGCATTGGCGTGGTCTTATTAGGT
GATTACTGGCAGCTACAGAGCGGTGATGAAGTTGAACGAACTGGGCGCGTTATGGACGTAGCCGTCGGGTTGGGATTATT
AGGGCGGGTGATTGATCCGCTCGGGCGTCCTCTTGATGATAAAGGGCCTATCGAGAGCAGCGAAAGATTACCCGTTGAAC
GCCCGGCTGCACCCATTATGGACAGGGCCCCCGTGACTGTGCCGTTGCAAACGGGATTAAAAGTGATCGATGCGTTGATT
CCGATTGGACGGGGCCAGCGTGAACTGATTTTAGGAGATCGCCAGACCGGTAAAACCACTATTGCGATCGACACTATTCT
CAACCAGCATGATCAAAATGTGCTCTGTGTTTATTGTGCTATTGGCCAGCGAGCTTCGGCAGTGGCGAAAACCATTGCCA
TATTAAAAGCGAAAGGTGCGCTGGATTATACTCTGGTGATGGTCAGTGAAGGCAATGCACCCCCTGGTTTTGCTTATATT
GCACCTTATGCAGCGACCAGTATTGCCGAGTACTTTATGGAAAAAGGGCGGGATGTTTTAATTGTGTATGACGATCTTAC
CCAGCATGCCCGCGCTTACCGCGAACTGTCCTTACTGCTGCGCAGACCACCGGGACGGGAAGCATTTCCCGGTGATATTT
TCTATATTCATTCGCGTTTATTAGAACGTGCGACCTGCTTAAAACAGAGACACAAGGGCGGATCTCTCACCGCTCTGCCA
ATTATCGAGACAGAAGCGCAAAATATTTCAGCTTATATCCCCACTAACCTTATATCTATTACCGACGGGCAAATTTACCT
GTCTCCAACGCTGTTCGAATTAGGCATATTACCTGCAGTTGATGTCGGTCGATCGGTCTCGCGTGTTGGCGGGAAAGCCC
AGCGGCCAATGTACCGCGCGGTTGCCGCTAATCTCAAATTAACCTATGCACAATTTGAAGAGCTGGAAACATTCGCCCGC
TTTGGCGCACGCCTAGATCAAAATTCACAGGACATCATTACCAATGGACGCCGGATTAGAGCTAGCCTTAAGCAGCCACA
GTCATCTCCCATGACAGTGTTAGAACAAATTACGGTATTAATAGCGTTAACCGAGAAGCTCTTTGACACTGTGCCACTCT
TAAAAATGAGAGAGGCAGAGCAGGCCTTATGTCTGGCGACAACGGAGCTTCCCGAAGACTTTCTGAGCCGCTTTAACAGC
GCCAAAATTTTAAGCGACGATGATCGTAACCGCATTATCGATATTGCACGTATTACCTTAGCTCCTTTTCAGTCGCCTCC
CGATGAGGACAATGGAATAACGTCAACCCCGAGTAACTAA

Upstream 100 bases:

>100_bases
CAACATGCTATAAGCCGCCAGAGTGGTAGTGATGATTCGTTGCCGGCAGGCGCGACCTCTTTAGCCACACAGTTTACGGA
AAAACAGGAAAACCTTCCTA

Downstream 100 bases:

>100_bases
AATAGCGGTCATAGATAACAGCGGGAAGAATCATTATGAGCGACAGTATAGACAGCAGTGATGTACTAAAACGAAAAATT
AACAGTGCCAGTGATTTACA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MTDLQQVVAHSFAALAASRTTFRAQLKAREIGIISSVSFGVAQVSGLANVASEEVLKFSGDIYGIAFNVDQDSIGVVLLG
DYWQLQSGDEVERTGRVMDVAVGLGLLGRVIDPLGRPLDDKGPIESSERLPVERPAAPIMDRAPVTVPLQTGLKVIDALI
PIGRGQRELILGDRQTGKTTIAIDTILNQHDQNVLCVYCAIGQRASAVAKTIAILKAKGALDYTLVMVSEGNAPPGFAYI
APYAATSIAEYFMEKGRDVLIVYDDLTQHARAYRELSLLLRRPPGREAFPGDIFYIHSRLLERATCLKQRHKGGSLTALP
IIETEAQNISAYIPTNLISITDGQIYLSPTLFELGILPAVDVGRSVSRVGGKAQRPMYRAVAANLKLTYAQFEELETFAR
FGARLDQNSQDIITNGRRIRASLKQPQSSPMTVLEQITVLIALTEKLFDTVPLLKMREAEQALCLATTELPEDFLSRFNS
AKILSDDDRNRIIDIARITLAPFQSPPDEDNGITSTPSN

Sequences:

>Translated_519_residues
MTDLQQVVAHSFAALAASRTTFRAQLKAREIGIISSVSFGVAQVSGLANVASEEVLKFSGDIYGIAFNVDQDSIGVVLLG
DYWQLQSGDEVERTGRVMDVAVGLGLLGRVIDPLGRPLDDKGPIESSERLPVERPAAPIMDRAPVTVPLQTGLKVIDALI
PIGRGQRELILGDRQTGKTTIAIDTILNQHDQNVLCVYCAIGQRASAVAKTIAILKAKGALDYTLVMVSEGNAPPGFAYI
APYAATSIAEYFMEKGRDVLIVYDDLTQHARAYRELSLLLRRPPGREAFPGDIFYIHSRLLERATCLKQRHKGGSLTALP
IIETEAQNISAYIPTNLISITDGQIYLSPTLFELGILPAVDVGRSVSRVGGKAQRPMYRAVAANLKLTYAQFEELETFAR
FGARLDQNSQDIITNGRRIRASLKQPQSSPMTVLEQITVLIALTEKLFDTVPLLKMREAEQALCLATTELPEDFLSRFNS
AKILSDDDRNRIIDIARITLAPFQSPPDEDNGITSTPSN
>Mature_518_residues
TDLQQVVAHSFAALAASRTTFRAQLKAREIGIISSVSFGVAQVSGLANVASEEVLKFSGDIYGIAFNVDQDSIGVVLLGD
YWQLQSGDEVERTGRVMDVAVGLGLLGRVIDPLGRPLDDKGPIESSERLPVERPAAPIMDRAPVTVPLQTGLKVIDALIP
IGRGQRELILGDRQTGKTTIAIDTILNQHDQNVLCVYCAIGQRASAVAKTIAILKAKGALDYTLVMVSEGNAPPGFAYIA
PYAATSIAEYFMEKGRDVLIVYDDLTQHARAYRELSLLLRRPPGREAFPGDIFYIHSRLLERATCLKQRHKGGSLTALPI
IETEAQNISAYIPTNLISITDGQIYLSPTLFELGILPAVDVGRSVSRVGGKAQRPMYRAVAANLKLTYAQFEELETFARF
GARLDQNSQDIITNGRRIRASLKQPQSSPMTVLEQITVLIALTEKLFDTVPLLKMREAEQALCLATTELPEDFLSRFNSA
KILSDDDRNRIIDIARITLAPFQSPPDEDNGITSTPSN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=484, Percent_Identity=46.0743801652893, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI4757810, Length=484, Percent_Identity=46.0743801652893, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI32189394, Length=376, Percent_Identity=25.531914893617, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI19913426, Length=321, Percent_Identity=28.3489096573209, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913428, Length=321, Percent_Identity=27.7258566978193, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI19913424, Length=250, Percent_Identity=24, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1790172, Length=453, Percent_Identity=47.2406181015453, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1790170, Length=358, Percent_Identity=27.3743016759777, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788251, Length=285, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=453, Percent_Identity=48.1236203090508, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71988080, Length=459, Percent_Identity=47.7124183006536, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71988074, Length=453, Percent_Identity=44.1501103752759, Blast_Score=383, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17510931, Length=323, Percent_Identity=28.4829721362229, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=356, Percent_Identity=26.685393258427, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=317, Percent_Identity=27.4447949526814, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17565854, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=443, Percent_Identity=48.0812641083521, Blast_Score=428, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6322581, Length=454, Percent_Identity=27.5330396475771, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=320, Percent_Identity=28.75, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24658560, Length=483, Percent_Identity=44.3064182194617, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI281361666, Length=320, Percent_Identity=28.125, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24646341, Length=320, Percent_Identity=28.125, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI17136796, Length=320, Percent_Identity=28.125, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24638766, Length=376, Percent_Identity=25.2659574468085, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI28574560, Length=359, Percent_Identity=27.8551532033426, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20129479, Length=306, Percent_Identity=23.202614379085, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583988, Length=203, Percent_Identity=25.615763546798, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583986, Length=203, Percent_Identity=25.615763546798, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583984, Length=203, Percent_Identity=25.615763546798, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583992, Length=203, Percent_Identity=25.615763546798, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA1_PSYIN (A1SS62)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_941926.1
- ProteinModelPortal:   A1SS62
- SMR:   A1SS62
- STRING:   A1SS62
- GeneID:   4626747
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0470
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   NVLCVYC
- ProtClustDB:   PRK09281
- BioCyc:   PING357804:PING_0470-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR017710
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR03324
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 56660; Mature: 56529

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLQQVVAHSFAALAASRTTFRAQLKAREIGIISSVSFGVAQVSGLANVASEEVLKFSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHCHHHHHHHHHHHHHHHHHHHHHCC
DIYGIAFNVDQDSIGVVLLGDYWQLQSGDEVERTGRVMDVAVGLGLLGRVIDPLGRPLDD
CEEEEEEECCCCCCCEEEEECCEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
KGPIESSERLPVERPAAPIMDRAPVTVPLQTGLKVIDALIPIGRGQRELILGDRQTGKTT
CCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEE
IAIDTILNQHDQNVLCVYCAIGQRASAVAKTIAILKAKGALDYTLVMVSEGNAPPGFAYI
EEEEHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEE
APYAATSIAEYFMEKGRDVLIVYDDLTQHARAYRELSLLLRRPPGREAFPGDIFYIHSRL
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LERATCLKQRHKGGSLTALPIIETEAQNISAYIPTNLISITDGQIYLSPTLFELGILPAV
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEECCCEEEEECCEEEECCHHHHHCCCCHH
DVGRSVSRVGGKAQRPMYRAVAANLKLTYAQFEELETFARFGARLDQNSQDIITNGRRIR
HCCCHHHHHCCCCCCCHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHH
ASLKQPQSSPMTVLEQITVLIALTEKLFDTVPLLKMREAEQALCLATTELPEDFLSRFNS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHCCC
AKILSDDDRNRIIDIARITLAPFQSPPDEDNGITSTPSN
CCEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDLQQVVAHSFAALAASRTTFRAQLKAREIGIISSVSFGVAQVSGLANVASEEVLKFSG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHCHHHHHHHHHHHHHHHHHHHHHCC
DIYGIAFNVDQDSIGVVLLGDYWQLQSGDEVERTGRVMDVAVGLGLLGRVIDPLGRPLDD
CEEEEEEECCCCCCCEEEEECCEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
KGPIESSERLPVERPAAPIMDRAPVTVPLQTGLKVIDALIPIGRGQRELILGDRQTGKTT
CCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEE
IAIDTILNQHDQNVLCVYCAIGQRASAVAKTIAILKAKGALDYTLVMVSEGNAPPGFAYI
EEEEHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEE
APYAATSIAEYFMEKGRDVLIVYDDLTQHARAYRELSLLLRRPPGREAFPGDIFYIHSRL
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LERATCLKQRHKGGSLTALPIIETEAQNISAYIPTNLISITDGQIYLSPTLFELGILPAV
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEECCCEEEEECCEEEECCHHHHHCCCCHH
DVGRSVSRVGGKAQRPMYRAVAANLKLTYAQFEELETFARFGARLDQNSQDIITNGRRIR
HCCCHHHHHCCCCCCCHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHH
ASLKQPQSSPMTVLEQITVLIALTEKLFDTVPLLKMREAEQALCLATTELPEDFLSRFNS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHCCC
AKILSDDDRNRIIDIARITLAPFQSPPDEDNGITSTPSN
CCEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA