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The map label for this gene is pgk [H]

Identifier: 119944151

GI number: 119944151

Start: 476362

End: 477534

Strand: Direct

Name: pgk [H]

Synonym: Ping_0371

Alternate gene names: 119944151

Gene position: 476362-477534 (Clockwise)

Preceding gene: 119944147

Following gene: 119944152

Centisome position: 10.45

GC content: 42.71

Gene sequence:

>1173_bases
ATGTCAGTAAAGAAAATGGTAGATCAAGATTTAGCAGGCAAACGCGTATTTATTCGTCAAGATCTTAATGTGCCAATTAA
AAACGGTAAAGTTACATCTGATGCGCGTATCCGTGCTTCTATCCCAACAATTAAACTAGCGTTAGAAAAAGGCGCTAAAT
TAATGATCACATCTCACTTAGGTCGTCCCGTTGAAGGCGGTACTGCTGAAGAAAATGCCGCATTCTCTCTACAACCTGTG
GTTGATTATTTAAATGAAGCGTTAGATGTGCCCGTCCGTTTAGTCACTGATTACTTAAATGGTCTGGAAGTAAACCCAGG
TGAAGTCGTTGTTCTGGAAAACGTTCGTTTTAATAAAGGTGAAAAGAAAGATGAAGAAGGTCTTGCTAAGCAACTTGCTG
CACTTTGTGATGTTTACGTAATGGATGCATTCGGTACGGCTCACCGTGCTCAAGCATCGACTCACGGCATTGCTAAATTT
GCGCCTGTCGCATGCGCAGGCCCATTACTTGCCGCTGAGCTTGAAGCATTAGGTAAAGCAATGGACAATCCGGCTCGCCC
GTTAGTAGCTATCGTGGGTGGTTCTAAAGTATCTACCAAGCTTACGGTACTTGAGTCTCTCTCTAAAATTGCTGACCAAC
TTGTTGTTGGTGGTGGTATTGCTAATACCTTTATTGCAGCACAAGGCCATAATGTTGGTAAATCATTATATGAAGCCGAC
TTAGTTGAAACAGCTAAAAAACTAATGGTTGACTGTGCTATTCCTGTTGCGACAGATGTTGCTTGTGCTAAAGCCTTTGA
TGAAAACGCAGAAGCCGTTATTAAAAACGTGGCAGACGTGCAAGATGATGACATGATCTTCGATTTAGGTCCTGATTCAA
CAGCTGTATTAGCGGCTATCCTAAAAGATGCTAAAACTATTCTTTGGAATGGCCCGGTTGGGGTTTTTGAGTTTAAAAAC
TTTGAAGCGGGTACTGCTGGTATCGCAAAAGCGATTGCTGAATCCGATGCGTTCTCTGTTGCTGGTGGTGGTGATACATT
AGCTGCTATCGATAAATTTGGTATTACTGCAGATGTTTCTTACATCTCAACGGGCGGTGGTGCTTTCCTTGAATTTGTTG
AAGGTAAAGTCTTACCCGCAGTGGCCATGCTAGAGTCACGTGCAAATGCTTAA

Upstream 100 bases:

>100_bases
ACCTTCTGCCTGGAAAGCCATCATTTATGGTCTTGCTGATGACTGCATCTTCAAGTAATTTCAGTATATATAGTTTTAAA
ATCAAATGAGAGGACTCATC

Downstream 100 bases:

>100_bases
GAAAACAGTTAAAACGAGATAAATGCTCGTTTTTTCAATTCGATCTGATTTTTAATTTTATCCAATTTCCATTTTCGTGC
TTTTCATCACAAAATTGTGT

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSVKKMVDQDLAGKRVFIRQDLNVPIKNGKVTSDARIRASIPTIKLALEKGAKLMITSHLGRPVEGGTAEENAAFSLQPV
VDYLNEALDVPVRLVTDYLNGLEVNPGEVVVLENVRFNKGEKKDEEGLAKQLAALCDVYVMDAFGTAHRAQASTHGIAKF
APVACAGPLLAAELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAQGHNVGKSLYEAD
LVETAKKLMVDCAIPVATDVACAKAFDENAEAVIKNVADVQDDDMIFDLGPDSTAVLAAILKDAKTILWNGPVGVFEFKN
FEAGTAGIAKAIAESDAFSVAGGGDTLAAIDKFGITADVSYISTGGGAFLEFVEGKVLPAVAMLESRANA

Sequences:

>Translated_390_residues
MSVKKMVDQDLAGKRVFIRQDLNVPIKNGKVTSDARIRASIPTIKLALEKGAKLMITSHLGRPVEGGTAEENAAFSLQPV
VDYLNEALDVPVRLVTDYLNGLEVNPGEVVVLENVRFNKGEKKDEEGLAKQLAALCDVYVMDAFGTAHRAQASTHGIAKF
APVACAGPLLAAELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAQGHNVGKSLYEAD
LVETAKKLMVDCAIPVATDVACAKAFDENAEAVIKNVADVQDDDMIFDLGPDSTAVLAAILKDAKTILWNGPVGVFEFKN
FEAGTAGIAKAIAESDAFSVAGGGDTLAAIDKFGITADVSYISTGGGAFLEFVEGKVLPAVAMLESRANA
>Mature_389_residues
SVKKMVDQDLAGKRVFIRQDLNVPIKNGKVTSDARIRASIPTIKLALEKGAKLMITSHLGRPVEGGTAEENAAFSLQPVV
DYLNEALDVPVRLVTDYLNGLEVNPGEVVVLENVRFNKGEKKDEEGLAKQLAALCDVYVMDAFGTAHRAQASTHGIAKFA
PVACAGPLLAAELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAQGHNVGKSLYEADL
VETAKKLMVDCAIPVATDVACAKAFDENAEAVIKNVADVQDDDMIFDLGPDSTAVLAAILKDAKTILWNGPVGVFEFKNF
EAGTAGIAKAIAESDAFSVAGGGDTLAAIDKFGITADVSYISTGGGAFLEFVEGKVLPAVAMLESRANA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=422, Percent_Identity=38.1516587677725, Blast_Score=241, Evalue=7e-64,
Organism=Homo sapiens, GI31543397, Length=422, Percent_Identity=37.4407582938389, Blast_Score=241, Evalue=9e-64,
Organism=Escherichia coli, GI1789294, Length=388, Percent_Identity=74.7422680412371, Blast_Score=575, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17508823, Length=417, Percent_Identity=40.5275779376499, Blast_Score=268, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6319857, Length=419, Percent_Identity=39.618138424821, Blast_Score=261, Evalue=9e-71,
Organism=Drosophila melanogaster, GI17136394, Length=414, Percent_Identity=42.2705314009662, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24581203, Length=410, Percent_Identity=38.5365853658537, Blast_Score=240, Evalue=1e-63,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 40754; Mature: 40623

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00111 PGLYCERATE_KINASE ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKKMVDQDLAGKRVFIRQDLNVPIKNGKVTSDARIRASIPTIKLALEKGAKLMITSHL
CCHHHHHHHCCCCCEEEEEECCCCCCCCCEECCCCEEEECCCEEEEEECCCCEEEEEECC
GRPVEGGTAEENAAFSLQPVVDYLNEALDVPVRLVTDYLNGLEVNPGEVVVLENVRFNKG
CCCCCCCCCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
EKKDEEGLAKQLAALCDVYVMDAFGTAHRAQASTHGIAKFAPVACAGPLLAAELEALGKA
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCHHHCCHHHHHHHHHHHHH
MDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAQGHNVGKSLYEAD
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCHHHHEEEECCCCHHHHHHHHH
LVETAKKLMVDCAIPVATDVACAKAFDENAEAVIKNVADVQDDDMIFDLGPDSTAVLAAI
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
LKDAKTILWNGPVGVFEFKNFEAGTAGIAKAIAESDAFSVAGGGDTLAAIDKFGITADVS
HHHCCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCEEEEH
YISTGGGAFLEFVEGKVLPAVAMLESRANA
EEECCCHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVKKMVDQDLAGKRVFIRQDLNVPIKNGKVTSDARIRASIPTIKLALEKGAKLMITSHL
CHHHHHHHCCCCCEEEEEECCCCCCCCCEECCCCEEEECCCEEEEEECCCCEEEEEECC
GRPVEGGTAEENAAFSLQPVVDYLNEALDVPVRLVTDYLNGLEVNPGEVVVLENVRFNKG
CCCCCCCCCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
EKKDEEGLAKQLAALCDVYVMDAFGTAHRAQASTHGIAKFAPVACAGPLLAAELEALGKA
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCHHHCCHHHHHHHHHHHHH
MDNPARPLVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAQGHNVGKSLYEAD
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCHHHHEEEECCCCHHHHHHHHH
LVETAKKLMVDCAIPVATDVACAKAFDENAEAVIKNVADVQDDDMIFDLGPDSTAVLAAI
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
LKDAKTILWNGPVGVFEFKNFEAGTAGIAKAIAESDAFSVAGGGDTLAAIDKFGITADVS
HHHCCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCEEEEH
YISTGGGAFLEFVEGKVLPAVAMLESRANA
EEECCCHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA